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ClinicalTrials.gov public records Last synced Jul 23, 2026, 11:16 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Breast Implantation Clear all
Completed Phase 3 Interventional Accepts healthy volunteers

The Use of Pecs Blocks in Combination With Exparel in Breast Reconstruction Surgery

NCT05171179
View directory record Official record
Conditions
Mammaplasty
Interventions
Breast Reconstruction (Mammaplasty), Pecs blocks, Exparel, Bupivacaine
Procedure · Device · Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 23, 2025 · Synced Jul 23, 2026, 11:16 AM EDT
Active, not recruiting Not applicable Interventional

Split Chest Breast Neurotization

NCT05757778
View directory record Official record
Conditions
Breast Implant; Complications
Interventions
Sensory Nerve Coaptation
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Jul 23, 2026, 11:16 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Autologous Fat Grafting to the Breast

NCT00775788
View directory record Official record
Conditions
Micromastia, Breast Ptosis, Implant Failure, Breast Reconstruction, Congenital Malformations
Interventions
Autologous Fat Grafting to Breasts
Procedure
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
17 Years to 70 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
2
States / cities
Metairie, Louisiana • New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Nov 17, 2008 · Synced Jul 23, 2026, 11:16 AM EDT
Completed Not applicable Interventional Results available

Sientra Sponsored Silimed Gel-Filled Breast Implant Core Clinical Study

NCT00905645
View directory record Official record
Conditions
Breast Augmentation, Breast Reconstruction, Breast Revision
Interventions
Silimed Gel-Filled Mammary Implant
Device
Lead sponsor
Tiger Biosciences, LLC.
Industry
Eligibility
18 Years and older · Female only
Enrollment
1,788 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2018
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Jan 10, 2024 · Synced Jul 23, 2026, 11:16 AM EDT
Completed Not applicable Interventional

Prospective Trial of Subcutaneous Versus Subpectoral 2-Staged Implant-Based Breast Reconstruction

NCT02775409
View directory record Official record
Conditions
Breast Reconstruction Following Mastectomy
Interventions
Subcutaneous placement, Submuscular placement
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 29, 2021 · Synced Jul 23, 2026, 11:16 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

NATRELLE® 410 Full and Moderate Height/Projection Breast Implant Continued Access Post-Approval Study

NCT01853605
View directory record Official record
Conditions
Breast Augmentation, Breast Reconstruction, Breast Implant Revision
Interventions
Anatomically shaped silicone gel-filled breast implants
Device
Lead sponsor
Allergan
Industry
Eligibility
18 Years and older · Female only
Enrollment
3,811 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2014
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 10, 2015 · Synced Jul 23, 2026, 11:16 AM EDT
Recruiting Not applicable Interventional

Impact of Pectoral Versus Paravertebral Blocks on Pain and Physical Well-Being in Implant-Based Breast Reconstruction

NCT07209436
View directory record Official record
Conditions
Breast Reconstruction
Interventions
Paravertebral block (single injection), Pectoral block
Procedure
Lead sponsor
Amy Colwell
Other
Eligibility
18 Years and older
Enrollment
212 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Jul 23, 2026, 11:16 AM EDT
Terminated Phase 2Phase 3 Interventional Results available

The Effect of Nitroglycerin Ointment, Fluorescent Angiography, and Incisional Negative Pressure Wound Therapy on Mastectomy Skin Flap Perfusion-Related Problems

NCT03716050
View directory record Official record
Conditions
Perfusion; Complications
Interventions
Nitroglycerin, Negative Pressure Wound Therapy/ Wound VAC, Fluorescent Angiography with indocyanine-green (not to exceed 5mg/kg), No treatment
Drug · Device · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 20, 2020 · Synced Jul 23, 2026, 11:16 AM EDT
Completed No phase listed Observational

Tissue Expansion in Breast Reconstruction Without Drains

NCT03784859
View directory record Official record
Conditions
Breast Cancer, Hereditary Breast and Ovarian Cancer Syndrome, Breast Implant; Complications
Interventions
Insertion of Tissue Expander with Fluid Reservoir
Device
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
21 Years and older · Female only
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 5, 2020 · Synced Jul 23, 2026, 11:16 AM EDT
Completed Not applicable Interventional

Reusable Versus Disposable Draping System in Breast Reconstruction Surgery

NCT01176786
View directory record Official record
Conditions
Mastectomy, Infections, Breast Reconstruction
Interventions
Culture Swabs, Rodac Plate Cultures
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Female only
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 6, 2017 · Synced Jul 23, 2026, 11:16 AM EDT
Completed Not applicable Interventional Results available

SERI® Surgical Scaffold for Soft Tissue Support in Revision Augmentation Surgery

NCT02030938
View directory record Official record
Conditions
Subjects Requiring Revision Breast Augmentation Surgery
Interventions
SERI® Surgical Scaffold
Device
Lead sponsor
Sofregen Medical, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
5
States / cities
La Jolla, California • San Francisco, California • Troy, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 27, 2021 · Synced Jul 23, 2026, 11:16 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Early Versus Standard Postpartum Insertion of the Etonogestrel Contraceptive Implant

NCT00847587
View directory record Official record
Conditions
Complications; Contraceptive, Female Lactation
Interventions
Etonogestrel contraceptive implant
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 17, 2016 · Synced Jul 23, 2026, 11:16 AM EDT
Recruiting Not applicable Interventional

Pulsed Lavage in Implant-Based Breast Reconstruction

NCT05585710
View directory record Official record
Conditions
Breast Reconstruction
Interventions
Pulsed Lavage Washout, Implant-based breast reconstruction, Bilateral or unilateral mastectomy, Tissue expander, Acellular dermal matrix
Other · Procedure · Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Jul 23, 2026, 11:16 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Labor and Delivery Implant Insertion: A Randomized Controlled Trial

NCT02866643
View directory record Official record
Conditions
Postpartum Contraception, Family Planning
Interventions
Etonogestrel-Immediate, Etonogestrel-Delayed
Drug
Lead sponsor
Stanford University
Other
Eligibility
Female only
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jul 24, 2022 · Synced Jul 23, 2026, 11:16 AM EDT
Recruiting Phase 2 Interventional

Microbiome and Association With Implant Infections

NCT05020574
View directory record Official record
Conditions
Breast Cancer, Breast Cancer Female, Genetic Predisposition to Disease
Interventions
Cephalexin
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Jul 23, 2026, 11:16 AM EDT
Active, not recruiting No phase listed Observational

Safety Follow-up Study in Subjects With Silicone Gel-filled Breast Implants as Compared Both to Saline-filled Breast Implants and to National Norms

NCT00443274
View directory record Official record
Conditions
Breast Implant
Interventions
NBIR - US National Breast Implant Registry, 410 Arm, BIFs - Breast Implant Follow-Up Study
Other · Device
Lead sponsor
Allergan
Industry
Eligibility
18 Years to 99 Years · Female only
Enrollment
56,460 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2029
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Jul 15, 2025 · Synced Jul 23, 2026, 11:16 AM EDT
Completed Not applicable Interventional Results available

Blossom Smart Expander Technology in Breast Reconstruction in Participants With Breast Cancer Undergoing Mastectomy

NCT03657069
View directory record Official record
Conditions
Breast Carcinoma, Breast Disorder
Interventions
Blossom, Breast-Q -Reconstruction module (preoperative) version 2.0 satisfaction with breasts questionnaire
Device · Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jan 21, 2024 · Synced Jul 23, 2026, 11:16 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Motiva Implants® Post-Approval Study

NCT06938399
View directory record Official record
Conditions
Breast Implant
Interventions
Silicone gel-filled breast implants - Motiva Implants®, Aesthetic Surgery
Device · Other
Lead sponsor
Motiva USA LLC
Industry
Eligibility
22 Years and older · Female only
Enrollment
2,400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2037
U.S. locations
33
States / cities
Beverly Hills, California • Camp Pendleton, California • Los Gatos, California + 26 more
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Jul 23, 2026, 11:16 AM EDT
Terminated Phase 2 Interventional Results available

A Prospective Trial to Reduce Post-Operative Pain in Implant Based Breast Reconstruction

NCT02044302
View directory record Official record
Conditions
Post-operative Pain
Interventions
Bupivacaine, Botulinum Toxins, Analgesics
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 9, 2017 · Synced Jul 23, 2026, 11:16 AM EDT
Terminated No phase listed Observational

Long Term Function Outcomes and Pain in Implant-based Post-mastectomy Breast Reconstruction

NCT04477538
View directory record Official record
Conditions
Post-mastectomy Breast Reconstruction
Interventions
Post-mastectomy breast reconstruction physical well-being survey
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 4, 2024 · Synced Jul 23, 2026, 11:16 AM EDT
Completed Not applicable Interventional

RCT Implant Based Breast Reconstruction

NCT04558138
View directory record Official record
Conditions
Mastectomy
Interventions
Discharge timing
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
19 Years to 80 Years · Female only
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Jul 23, 2026, 11:16 AM EDT
Recruiting Not applicable Interventional

Randomized Feasibility Trial for Mesh in Pre-Pectoral Reconstruction

NCT05190978
View directory record Official record
Conditions
Breast Cancer, Breast Implant; Complications, Infection or Inflammation
Interventions
Acellular Dermal Matrix, Reconstruction without ADM
Device · Procedure
Lead sponsor
University of California, Los Angeles
Other
Eligibility
22 Years to 75 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Jul 23, 2026, 11:16 AM EDT
Recruiting Not applicable Interventional

Breast Mesh Used in Two-staged Breast Reconstruction

NCT04967976
View directory record Official record
Conditions
Breast Cancer, Radiation, Breast Reconstruction, Synthetic Mesh
Interventions
TiLoop Bra mesh in expander-implant breast reconstrution, sub-pectoral expander-implant breast reconstruction
Procedure
Lead sponsor
Tianjin Medical University Cancer Institute and Hospital
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 19, 2021 · Synced Jul 23, 2026, 11:16 AM EDT
Recruiting Not applicable Interventional

Tissue Reinforcement for Breast Reconstruction (TRBR) Pivotal Clinical Study (REDEFINE)

NCT06556654
View directory record Official record
Conditions
Breast Reconstruction Surgery
Interventions
TRBR Device
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
22 Years and older · Female only
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
20
States / cities
Scottsdale, Arizona • Tucson, Arizona • Irvine, California + 15 more
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Jul 23, 2026, 11:16 AM EDT