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Showing 1–24 of 99 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Breast Lymphedema Clear all
Completed Phase 2 Interventional

Acupuncture for the Treatment of Chronic Lymphedema

NCT01003951
View directory record Official record
Conditions
Breast Cancer, Lymphedema
Interventions
Acupuncture
Procedure
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 15, 2012 · Synced Sep 14, 2026, 2:50 PM EDT
Completed Not applicable Interventional

Pilot Usability and Feasibility Testing on Kinect-Enhanced Training System for Lymphatic Exercises

NCT03999177
View directory record Official record
Conditions
Breast Cancer, Lymphedema
Interventions
Kinect-TOLF Training System
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years to 90 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 9, 2020 · Synced Sep 14, 2026, 2:50 PM EDT
Completed No phase listed Observational

Self-Care for Lymphedema in Patients With Breast Cancer

NCT00670644
View directory record Official record
Conditions
Breast Cancer
Interventions
questionnaire administration, survey administration, quality-of-life assessment
Other · Procedure
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 120 Years · Female only
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
3
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 9, 2017 · Synced Sep 14, 2026, 2:50 PM EDT
Completed Not applicable Interventional

Non-Invasive Imaging for Cording in Breast Cancer Patients

NCT01427166
View directory record Official record
Conditions
Breast Cancer
Interventions
Non invasive venous ultrasound
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 15, 2016 · Synced Sep 14, 2026, 2:50 PM EDT
Completed Early Phase 1 Interventional

Single-Photon Emission Computed Tomography, Computed Tomography Lymphoscintigraphy, and Intensity-Modulated Radiation Therapy in Treating Patients Who Have Undergone Surgery for Stage I or Stage II Breast Cancer

NCT00743314
View directory record Official record
Conditions
Breast Cancer, Lymphedema
Interventions
screening questionnaire administration, computed tomography, lymphoscintigraphy, single photon emission computed tomography, intensity-modulated radiation therapy, technetium Tc 99m sulfur colloid
Other · Procedure · Radiation
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 120 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 8, 2018 · Synced Sep 14, 2026, 2:50 PM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

LYT-100 in Patients With BCRL

NCT04243837
View directory record Official record
Conditions
Breast Cancer Related Lymphoedema, Lymphoedema
Interventions
LYT-100 BCRL, Placebo BCRL
Drug
Lead sponsor
PureTech
Industry
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
4
States / cities
Duarte, California • Los Angeles, California • Maitland, Florida + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 22, 2024 · Synced Sep 14, 2026, 2:50 PM EDT
Recruiting Not applicable Interventional

LYMPHA Procedure for the Prevention of Lymphedema After Axillary Lymphadenectomy

NCT05366699
View directory record Official record
Conditions
Lymphedema, Breast Cancer, Lymphedema
Interventions
axillary lymphadenectomy with immediate lymphatic reconstruction (LYMPHA), Axillary lymphadenetomy alone, axillary lymphadenectomy with soft tissue reinforcement
Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2030
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 14, 2026, 2:50 PM EDT
Terminated Not applicable Interventional

Identification of a Screening Tool and Treatment of Lymphedema Secondary to the Management of Breast Cancer Study

NCT00282529
View directory record Official record
Conditions
Breast Cancer, Lymphedema
Interventions
High Risk Lymphedema Education and Device Intervention
Device
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 23, 2017 · Synced Sep 14, 2026, 2:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Bioelectrical Impedance for Self-monitoring of Lymphedema

NCT01385488
View directory record Official record
Conditions
Lymphedema
Interventions
self-monitor arm volume
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
21 Years and older
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 9, 2017 · Synced Sep 14, 2026, 2:50 PM EDT
Completed No phase listed Observational

Exercise Program of Breast Cancer Patients Undergoing Chemotherapy With or Without Radiation

NCT01157767
View directory record Official record
Conditions
Breast Cancer
Interventions
standardized regimen of exercises, including a warm-up period, ROM arm exercises, and strength training exercises.
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 31, 2021 · Synced Sep 14, 2026, 2:50 PM EDT
Completed Not applicable Interventional

Expressive Writing in Improving Quality of Life in Patients With Breast Cancer and Lymphedema

NCT00679185
View directory record Official record
Conditions
Breast Cancer, Fatigue, Lymphedema
Interventions
expressive writing
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
21 Years to 80 Years · Female only
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
3
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 9, 2017 · Synced Sep 14, 2026, 2:50 PM EDT
Completed Phase 1 Interventional

A Pilot Study of VEGF Inhibition in Patients With Lymphedema Following Breast Cancer Treatment

NCT00393497
View directory record Official record
Conditions
Breast Cancer, Lymphedema
Interventions
bevacizumab
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older · Female only
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 21, 2014 · Synced Sep 14, 2026, 2:50 PM EDT
Completed Not applicable Interventional Results available

Lymphedema Prophylaxis in Breast Cancer Survivors Who Show Early Evidence of High-risk Status

NCT00383500
View directory record Official record
Conditions
Lymphedema, Breast Cancer
Interventions
Flexitouch, Class 1 compression garment
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 29, 2017 · Synced Sep 14, 2026, 2:50 PM EDT
Completed No phase listed Observational

BCRL Prevention Pilot

NCT01166672
View directory record Official record
Conditions
Obesity, Breast Cancer
Interventions
Not listed
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 11, 2012 · Synced Sep 14, 2026, 2:50 PM EDT
Completed Phase 4 Interventional

A Comparison of Dermal Autograft to AlloDerm in Breast Reconstruction

NCT01561287
View directory record Official record
Conditions
Mastectomy Related Lymphedema, Breast Reconstruction, Breast Cancer
Interventions
Dermal Autograft, AlloDerm
Procedure
Lead sponsor
University of Kentucky
Other
Eligibility
Female only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated May 10, 2016 · Synced Sep 14, 2026, 2:50 PM EDT
Recruiting Phase 4 Interventional

Post-mastectomy Recovery: Comparing Preoperative PECS-II Blocks With Intraoperative Pectoral Blocks

NCT06574022
View directory record Official record
Conditions
Mastectomy; Lymphedema, Breast Cancer
Interventions
Bupivacain, Exparel, Intraoperative Pecs II block (IOB) & superior AT (EX or BP), Preoperative Pecs II block (POB) & superior AT (EX or BP)
Drug · Procedure
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Sep 14, 2026, 2:50 PM EDT
Completed Not applicable Interventional Results available

Treatment of Breast Cancer-related Lymphedema With a Negative Pressure Device

NCT03252145
View directory record Official record
Conditions
Lymphedema, Secondary, Lymphedema of Upper Limb
Interventions
PhysioTouch, Manual Lymph Drainage (MLD)
Device · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 14, 2021 · Synced Sep 14, 2026, 2:50 PM EDT
Not listed Not applicable Interventional

The Use of Bioimpedance to Determine Pre-Clinical Lymphedema in the Post-Operative Breast Cancer Patient

NCT01521000
View directory record Official record
Conditions
Breast Cancer
Interventions
Garment Sleeve
Device
Lead sponsor
Main Line Health
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Bryn Mawr, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 29, 2012 · Synced Sep 14, 2026, 2:50 PM EDT
Completed Phase 4 Interventional Results available

Low Level Laser Treatment and Breast Cancer Related Lymphedema

NCT00852930
View directory record Official record
Conditions
Lymphedema
Interventions
laser and MLD combined, laser alone, manual lymphatic drainage
Procedure
Lead sponsor
Vanderbilt University
Other
Eligibility
21 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 10, 2017 · Synced Sep 14, 2026, 2:50 PM EDT
Not listed Phase 1 Interventional

Safety Study of Bevacizumab to Treat Women With a History of Breast Cancer and Suffering From Upper Extremity Lymphedema

NCT00318513
View directory record Official record
Conditions
Lymphedema
Interventions
Bevacizumab
Drug
Lead sponsor
Premiere Oncology of Arizona
Other
Eligibility
0 Years and older · Female only
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated May 9, 2006 · Synced Sep 14, 2026, 2:50 PM EDT
Not listed Not applicable Interventional

The Effect of Hand Exercises on Upper Limb Volume, Quality of Life, and Hand Function in Breast Cancer Survivors

NCT05983380
View directory record Official record
Conditions
Breast Cancer Lymphedema
Interventions
Hand Mobility and Grip Strengthening Exercises, Usual Care
Other
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
3
States / cities
Albuquerque, New Mexico • Rio Rancho, New Mexico • Santa Fe, New Mexico
Source: ClinicalTrials.gov public record
Updated Apr 16, 2024 · Synced Sep 14, 2026, 2:50 PM EDT
Active, not recruiting Phase 3 Interventional

Axillary Reverse Mapping in Preventing Lymphedema in Patients With Breast Cancer Undergoing Axillary Lymph Node Dissection

NCT03927027
View directory record Official record
Conditions
Breast Cancer Stage I, Breast Cancer Stage II, Breast Cancer Stage III
Interventions
Isosulfan Blue, Axillary Lymph Node Dissection, Mapping, Quality-of-Life Assessment, Questionnaire Administration
Drug · Procedure · Other
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
18 Years and older · Female only
Enrollment
534 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
96
States / cities
Little Rock, Arkansas • La Jolla, California • Martinez, California + 75 more
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Sep 14, 2026, 2:50 PM EDT
Completed Not applicable Interventional Results available

Home-based Compression Therapy for Arm and Truncal Lymphedema in Breast Cancer

NCT00880022
View directory record Official record
Conditions
Arm Lymphedema, Truncal Lymphedema, Breast Cancer
Interventions
Flexitouch System
Device
Lead sponsor
Vanderbilt University
Other
Eligibility
21 Years and older
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 4, 2017 · Synced Sep 14, 2026, 2:50 PM EDT
Completed Not applicable Interventional

Aquatic Exercise Study for Breast Cancer Patients With Lymphedema

NCT00498771
View directory record Official record
Conditions
Lymphedema
Interventions
Aquatic Exercise arm
Behavioral
Lead sponsor
Baylor Research Institute
Other
Eligibility
21 Years to 90 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 11, 2017 · Synced Sep 14, 2026, 2:50 PM EDT