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ClinicalTrials.gov public records Last synced Oct 4, 2026, 5:10 PM EDT

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Showing 73–96 of 100 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Breast Lymphedema Clear all
Completed Not applicable Interventional Results available

Intraoperative Evaluation of Axillary Lymphatics

NCT05094102
View directory record Official record
Conditions
Lymphedema, Surgery, Breast Cancer
Interventions
OnLume Imaging System, Indocyanine green
Device · Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older · Female only
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 13, 2024 · Synced Oct 4, 2026, 5:10 PM EDT
Completed Phase 2 Interventional

Horse Chestnut Seed Extract for Lymphedema

NCT00213928
View directory record Official record
Conditions
Lymphedema of Arm
Interventions
Horse Chestnut Seed Extract
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
17 Years and older · Female only
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 2, 2015 · Synced Oct 4, 2026, 5:10 PM EDT
Terminated Not applicable Interventional

Intensive Education in Increasing Understanding of Lymphedema in Patients With Breast Cancer Undergoing Surgery

NCT02073045
View directory record Official record
Conditions
Breast Cancer, Lymphedema
Interventions
educational intervention, lymphedema survey
Other
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 23, 2015 · Synced Oct 4, 2026, 5:10 PM EDT
Recruiting No phase listed Observational

Screening For BCRL In Targeted Therapy For Breast Cancer

NCT05142800
View directory record Official record
Conditions
Lymphedema, Lymphedema Arm, Lymphedema of Upper Arm, Lymphedema of Upper Limb, Lymphedema of the Hands, Edema, Edema Arm, Breast Cancer Lymphedema, Breast Cancer Metastatic, Breast Cancer Stage, Breast Cancer
Interventions
Perometer, SOZO device
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
261 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 4, 2026, 5:10 PM EDT
Completed Phase 2 Interventional

Pycnogenol for the Treatment of Lymphedema of the Arm in Breast Cancer Survivors

NCT00064857
View directory record Official record
Conditions
Lymphedema, Breast, Cancer
Interventions
Pycnogenol
Drug
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 22, 2008 · Synced Oct 4, 2026, 5:10 PM EDT
Terminated Not applicable Interventional

Hatha Yoga in Breast Cancer Survivors

NCT02923037
View directory record Official record
Conditions
Breast Carcinoma, Lymphedema
Interventions
Yoga, tape measurement of arm, Quality-of-Life Assessment, ldex measurement of arms
Procedure · Other
Lead sponsor
Vanderbilt-Ingram Cancer Center
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 26, 2019 · Synced Oct 4, 2026, 5:10 PM EDT
Recruiting Phase 4 Interventional

Post-mastectomy Recovery: Comparing Preoperative PECS-II Blocks With Intraoperative Pectoral Blocks

NCT06574022
View directory record Official record
Conditions
Mastectomy; Lymphedema, Breast Cancer
Interventions
Bupivacain, Exparel, Intraoperative Pecs II block (IOB) & superior AT (EX or BP), Preoperative Pecs II block (POB) & superior AT (EX or BP)
Drug · Procedure
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Oct 4, 2026, 5:10 PM EDT
Recruiting No phase listed Observational

Lymphedema Surveillance Study

NCT02743858
View directory record Official record
Conditions
Breast Cancer, Lymphedema
Interventions
Bilateral arm measurements, Body mass index (BMI), Quality of Life Questionnaire, Blood draw
Other · Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
1,250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2027
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Oct 4, 2026, 5:10 PM EDT
Not listed Not applicable Interventional

The Use of Bioimpedance to Determine Pre-Clinical Lymphedema in the Post-Operative Breast Cancer Patient

NCT01521000
View directory record Official record
Conditions
Breast Cancer
Interventions
Garment Sleeve
Device
Lead sponsor
Main Line Health
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Bryn Mawr, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 30, 2012 · Synced Oct 4, 2026, 5:10 PM EDT
Completed Not applicable Interventional Results available

Treatment of Breast Cancer-related Lymphedema With a Negative Pressure Device

NCT03252145
View directory record Official record
Conditions
Lymphedema, Secondary, Lymphedema of Upper Limb
Interventions
PhysioTouch, Manual Lymph Drainage (MLD)
Device · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 15, 2021 · Synced Oct 4, 2026, 5:10 PM EDT
Completed Not applicable Interventional

Enhancing Management of Chronic Pain and Symptoms Among Women Treated for Breast Cancer (Lymph-Flow)

NCT02462226
View directory record Official record
Conditions
Breast Cancer, Pain, Lymphedema
Interventions
The-Optimal-Lymph-Flow, Arm Precaution
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years to 89 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 20, 2017 · Synced Oct 4, 2026, 5:10 PM EDT
Not listed Not applicable Interventional

Same-Day Discharge After Nipple-sparing Mastectomy or Skin-sparing Mastectomy With Breast Reconstruction

NCT04596683
View directory record Official record
Conditions
Breast Cancer, Mastectomy; Lymphedema, Same Day Surgery, Nipple-sparing Mastectomy, Skin-sparing Mastectomy
Interventions
Same-day NSM or SSM
Procedure
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 22, 2020 · Synced Oct 4, 2026, 5:10 PM EDT
Recruiting Not applicable Interventional

Lymphovenous Bypass Procedure Before Underarm Lymph Node Surgery in Preventing Lymphedema in Patients With Inflammatory or Locally Advanced Non-inflammatory Breast Cancer or Melanoma

NCT03941756
View directory record Official record
Conditions
Anatomic Stage III Breast Cancer AJCC v8, Breast Inflammatory Carcinoma, Locally Advanced Breast Carcinoma, Melanoma
Interventions
Indocyanine Green, Lymphangiography, Lymphovenous Bypass
Drug · Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
252 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Oct 4, 2026, 5:10 PM EDT
Completed Not applicable Interventional

Liposuction for Arm Lymphedema Following Breast Cancer Surgery

NCT00816985
View directory record Official record
Conditions
Breast Cancer
Interventions
Liposuction, Quality of Life Questionnaires
Procedure · Other
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2021
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jun 24, 2021 · Synced Oct 4, 2026, 5:10 PM EDT
Terminated Not applicable Interventional Results available

Early Detection and Intervention for Mild and Moderate Lymphedema in Patients Treated for Breast Cancer

NCT00959985
View directory record Official record
Conditions
Lymphedema, Breast Cancer
Interventions
Compression Sleeve, Short-Stretch Compression Bandage
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 30, 2017 · Synced Oct 4, 2026, 5:10 PM EDT
Recruiting No phase listed Observational

Prediction Of Lymphedema In Patients With Inflammatory BreastCancer Using Preoperative Bioimpedance Measurements

NCT07855627
View directory record Official record
Conditions
Lymphedema, Inflammatory Breast Cancer (IBC), Preoperative, Bioimpedance Measurement
Interventions
Neoadjuvant therapy
Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 4, 2026, 5:10 PM EDT
Recruiting Not applicable Interventional

LymphBridge: Surgical Evaluation for Breast Cancer-Associated Lymphedema (BioBridge)

NCT04606030
View directory record Official record
Conditions
Lymphedema, Edema
Interventions
BioBridge® Collagen Matrix, Vascularized Lymph Node Transfer (VLNT)
Device · Procedure
Lead sponsor
Fibralign Corporation
Industry
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
2
States / cities
Chicago, Illinois • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 11, 2025 · Synced Oct 4, 2026, 5:10 PM EDT
Completed Not applicable Interventional

Pilot Usability and Feasibility Testing on Kinect-Enhanced Training System for Lymphatic Exercises

NCT03999177
View directory record Official record
Conditions
Breast Cancer, Lymphedema
Interventions
Kinect-TOLF Training System
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years to 90 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 10, 2020 · Synced Oct 4, 2026, 5:10 PM EDT
Recruiting Not applicable Interventional

A Non-randomized, Open-Label Study to Evaluate the Safety and Effectiveness of the Dayspring Technology for Patients With Breast Cancer Related Lymphedema (BCRL) After Lymphatic Surgery

NCT04888975
View directory record Official record
Conditions
Lymphedema, Lymphedema, Breast Cancer, Lymphedema Arm
Interventions
Dayspring Active Wearable Compression System
Device
Lead sponsor
Koya Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated May 20, 2021 · Synced Oct 4, 2026, 5:10 PM EDT
Completed Not applicable Interventional Results available

Study of Prone Accelerated Breast And Nodal IMRT

NCT02308488
View directory record Official record
Conditions
Lymphedema
Interventions
Intensity-modulated radiation therapy (IMRT)
Radiation
Lead sponsor
NYU Langone Health
Other
Eligibility
36 Years to 90 Years · Female only
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 27, 2023 · Synced Oct 4, 2026, 5:10 PM EDT
Completed No phase listed Interventional Results available

Education With or Without Exercise and Counseling in Preventing Lymphedema in Women With Stage I, Stage II, or Stage III Breast Cancer Who Are Undergoing Axillary Lymph Node Dissection

NCT00376597
View directory record Official record
Conditions
Lymphedema
Interventions
quality of life assessment, educational intervention, Physical therapy
Other · Procedure
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2017
U.S. locations
76
States / cities
Castro Valley, California • Concord, California • Fremont, California + 58 more
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 4, 2026, 5:10 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Morbidity After Diagnosis and Treatment of Breast Cancer Patients

NCT00027118
View directory record Official record
Conditions
Breast Cancer, Shoulder, Lymphedema, Fatigue
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years to 85 Years
Enrollment
326 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Oct 4, 2026, 5:10 PM EDT
Not listed Phase 1 Interventional

Safety Study of Bevacizumab to Treat Women With a History of Breast Cancer and Suffering From Upper Extremity Lymphedema

NCT00318513
View directory record Official record
Conditions
Lymphedema
Interventions
Bevacizumab
Drug
Lead sponsor
Premiere Oncology of Arizona
Other
Eligibility
0 Years and older · Female only
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated May 10, 2006 · Synced Oct 4, 2026, 5:10 PM EDT
Terminated Phase 1Phase 2 Interventional Results available

Axillary Lymph Node Preservation Surgery in Reducing Lymphedema in Patients With Breast Cancer

NCT00932035
View directory record Official record
Conditions
Breast Cancer
Interventions
axillary lymph node dissection, isosulfan blue based lymphatic mapping, quality-of-life assessment, Questionnaire administration
Procedure · Drug · Other
Lead sponsor
City of Hope Medical Center
Other
Eligibility
Female only
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
3
States / cities
Duarte, California • Sacramento, California • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 7, 2017 · Synced Oct 4, 2026, 5:10 PM EDT