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ClinicalTrials.gov public records Last synced Oct 21, 2026, 10:42 PM EDT

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Showing 1–24 of 56 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Breast Tomosynthesis Clear all
Completed Early Phase 1 Interventional

A Comparison of Breast Tomosynthesis Mammography and Conventional Breast Imaging in the Characterization of Breast Masses

NCT00826488
View directory record Official record
Conditions
Fibrocystic Disease of Breast, Breast Cancer
Interventions
Digital Breast Tomosynthesis
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
35 Years to 80 Years · Female only
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 2, 2015 · Synced Oct 21, 2026, 10:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Molecular Breast Imaging and Digital Breast Tomosynthesis in Screening Patients With Dense Breast Tissue

NCT03220893
View directory record Official record
Conditions
Breast Carcinoma
Interventions
Digital Breast Tomosynthesis (DBT), Scintimammography
Procedure · Radiation
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years to 75 Years · Female only
Enrollment
3,023 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
5
States / cities
Detroit, Michigan • Rochester, Minnesota • Toledo, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 21, 2026, 10:42 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Evaluating Image Quality and Comfort of an Investigational Curved Paddle Compared to a Standard Paddle

NCT03611543
View directory record Official record
Conditions
Breast Cancer
Interventions
Standard of Care Flat Paddle, Investigational Curved Paddle
Device
Lead sponsor
Hologic, Inc.
Industry
Eligibility
25 Years and older · Female only
Enrollment
443 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
4
States / cities
Stamford, Connecticut • Rochester, New York • Addison, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated May 21, 2025 · Synced Oct 21, 2026, 10:42 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Delphinus SoftVue Prospective Case Collection - ARM 1

NCT03257839
View directory record Official record
Conditions
Breast Neoplasms
Interventions
Routine Full-Field Digital Mammography, Routine Digital Breast Tomosynthesis, Automated Whole Breast Ultrasound
Device
Lead sponsor
Delphinus Medical Technologies, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
7,409 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
10
States / cities
Los Angeles, California • Miami Beach, Florida • Savannah, Georgia + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 5, 2021 · Synced Oct 21, 2026, 10:42 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Acquisition of Breast Mammography Images

NCT02156258
View directory record Official record
Conditions
Breast Cancer
Interventions
FFDM Mammography, DBT Mammography
Device
Lead sponsor
Fujifilm Medical Systems USA, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
1,232 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
5
States / cities
Scottsdale, Arizona • Iowa City, Iowa • Rochester, New York + 2 more
Source: ClinicalTrials.gov public record
Updated May 20, 2020 · Synced Oct 21, 2026, 10:42 PM EDT
Completed Not applicable Interventional

Evaluation of a 3-D Tomosynthesis Mammography System Used in Conjunction With Conventional 2-D Digital Mammography

NCT00754598
View directory record Official record
Conditions
Breast Cancer
Interventions
Tomosynthesis digital mammography imaging system
Device
Lead sponsor
Hologic, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
1,183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
5
States / cities
New Haven, Connecticut • Iowa City, Iowa • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 12, 2022 · Synced Oct 21, 2026, 10:42 PM EDT
Completed No phase listed Observational

Simulated Screening Study for Breast Imaging

NCT01807754
View directory record Official record
Conditions
Breast Cysts, Breast Tumors
Interventions
X-ray and ultrasound imaging scanning, Photoacoustic imaging scans for breast cancer screening
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
30 Years to 80 Years · Female only
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 21, 2020 · Synced Oct 21, 2026, 10:42 PM EDT
Active, not recruiting Not applicable Interventional

Project 1: Self-Triage by 2D Full-field Digital Mammography or Synthetic Images

NCT05960188
View directory record Official record
Conditions
Breast Cancer Screening
Interventions
AI Opinion
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 21, 2026, 10:42 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Biennial CEM in Women With a Personal History of Breast Cancer

NCT06105749
View directory record Official record
Conditions
Breast Cancer, Breast Neoplasms, Breast Cancer Female, Neoplasms
Interventions
contrast-enhanced mammography
Device
Lead sponsor
Wendie Berg
Other
Eligibility
30 Years to 79 Years · Female only
Enrollment
1,600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2031
U.S. locations
6
States / cities
Bethel Park, Pennsylvania • Cranberry Township, Pennsylvania • Monroeville, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 21, 2026, 10:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Multi-Reader Multi-Case Controlled Clinical Trial to Assess the Fujifilm FFDM and DBT Reader Training Program

NCT02685566
View directory record Official record
Conditions
Breast Cancer
Interventions
FFDM Plus DBT, FFDM
Device
Lead sponsor
Fujifilm Medical Systems USA, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
5
States / cities
Scottsdale, Arizona • Iowa City, Iowa • Rochester, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 21, 2023 · Synced Oct 21, 2026, 10:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Assessment of Digital Breast Tomosynthesis (DBT) in the Screening Environment

NCT01106911
View directory record Official record
Conditions
Breast Abnormalities
Interventions
tomosynthesis and screening mammography
Device
Lead sponsor
University of Pittsburgh
Other
Eligibility
35 Years to 55 Years · Female only
Enrollment
1,080 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2010
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 25, 2016 · Synced Oct 21, 2026, 10:42 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Comparison of Breast Cancer Screening With CESM to DBT in Women With Dense Breasts

NCT05625659
View directory record Official record
Conditions
Breast Cancer
Interventions
Dual-Energy Contrast-Enhanced Spectral Mammography (CESM)
Diagnostic Test
Lead sponsor
American College of Radiology
Other
Eligibility
45 Years to 74 Years · Female only
Enrollment
2,032 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
12
States / cities
Birmingham, Alabama • Boca Raton, Florida • The Villages, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 21, 2026, 10:42 PM EDT
Completed Early Phase 1 Interventional

Detection and/or Evaluation of Dense Breast Abnormalities Using Tomosynthesis and Digital Mammography

NCT00722059
View directory record Official record
Conditions
Breast Neoplasms, Breast Abnormalities
Interventions
Breast Tomosynthesis
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
30 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 3, 2014 · Synced Oct 21, 2026, 10:42 PM EDT
Terminated Early Phase 1 Interventional

Comparison of CE-DBT and MRI in Patients With Known Breast Lesions

NCT05754749
View directory record Official record
Conditions
Breast Cancer
Interventions
Iohexol 350 Mg/mL Injectable Solution
Drug
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 21, 2026, 10:42 PM EDT
Completed Not applicable Interventional Results available

Efficacy of Digital Breast Tomosynthesis + Standard 2- Dimensional Mammography in Breast Cancer

NCT03190083
View directory record Official record
Conditions
Breast Cancer
Interventions
2-dimensional mammogram, digital breast tomosynthesis (DBT)
Device
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
25 Years to 85 Years · Female only
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 27, 2022 · Synced Oct 21, 2026, 10:42 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

B.Brilliant Revelation Comparision Study

NCT07067788
View directory record Official record
Conditions
Breast Cancer Screening
Interventions
Breast Imaging
Diagnostic Test
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 24, 2026 · Synced Oct 21, 2026, 10:42 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers Results available

Abbreviated Breast MRI and Digital Tomosynthesis Mammography in Screening Women With Dense Breasts

NCT02933489
View directory record Official record
Conditions
Asymptomatic
Interventions
Contrast-enhanced Magnetic Resonance Imaging, Digital Tomosynthesis Mammography, Quality-of-Life Assessment, Questionnaire Administration
Diagnostic Test · Other
Lead sponsor
ECOG-ACRIN Cancer Research Group
Network
Eligibility
40 Years to 75 Years · Female only
Enrollment
1,516 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2026
U.S. locations
67
States / cities
Gilbert, Arizona • Pasadena, California • Denver, Colorado + 54 more
Source: ClinicalTrials.gov public record
Updated Feb 25, 2026 · Synced Oct 21, 2026, 10:42 PM EDT
Completed No phase listed Observational

Delphinus SoftVue Prospective Case Collection - ARM 2

NCT02977247
View directory record Official record
Conditions
Breast Neoplasms
Interventions
Non-Interventional, Automated Whole Breast Ultrasound
Other · Device
Lead sponsor
Delphinus Medical Technologies, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
1,150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
10
States / cities
Los Angeles, California • Miami Beach, Florida • Savannah, Georgia + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 5, 2021 · Synced Oct 21, 2026, 10:42 PM EDT
Not listed No phase listed Observational

Assessing Breast Density's Value in Imaging - A Comparative Effectiveness Study

NCT02980848
View directory record Official record
Conditions
Breast Cancer
Interventions
Screening digital mammography, Screening digital breast tomosynthesis, Screening breast magnetic resonance imaging, Diagnostic mammography, Pre-operative breast magnetic resonance imaging
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 89 Years · Female only
Enrollment
1,341,172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
7
States / cities
Davis, California • San Francisco, California • Chicago, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated Nov 17, 2021 · Synced Oct 21, 2026, 10:42 PM EDT
Terminated Not applicable Interventional Results available

Assessment of Diagnostic Accuracy and Performance of Digital Breast Tomosynthesis Compared to Mammography

NCT02540083
View directory record Official record
Conditions
Breast Cancer, Tumors, Breast
Interventions
DBT and FFDM
Device
Lead sponsor
GE Healthcare
Industry
Eligibility
30 Years and older · Female only
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
2
States / cities
Greenville, North Carolina • Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Feb 5, 2019 · Synced Oct 21, 2026, 10:42 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

A Comparison of Recall Rates Between Conventional 2d Mammography and 2d Plus 3d (Tomosynthesis) Mammography in a Screening Population

NCT01569802
View directory record Official record
Conditions
Breast Cancer
Interventions
Not listed
Lead sponsor
Rose Imaging Specialists, P.A.
Other
Eligibility
30 Years and older · Female only
Enrollment
10,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2012
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 3, 2012 · Synced Oct 21, 2026, 10:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Assessment of Periodic Screening of Women With Denser Breast Using WBUS and DBT

NCT02643966
View directory record Official record
Conditions
Breast Cancer
Interventions
Whole breast ultrasound
Device
Lead sponsor
Wendie Berg
Other
Eligibility
40 Years to 75 Years · Female only
Enrollment
6,266 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2022
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 29, 2023 · Synced Oct 21, 2026, 10:42 PM EDT
Completed Not applicable Interventional Results available

Computed Tomography Versus Standard 2D Mammography Versus 3D Tomosynthesis

NCT01852032
View directory record Official record
Conditions
Breast Cancer
Interventions
Tomosynthesis Breast Scanning, Breast CT Scanning
Radiation
Lead sponsor
University of California, Davis
Other
Eligibility
35 Years and older · Female only
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Apr 17, 2018 · Synced Oct 21, 2026, 10:42 PM EDT
Completed Not applicable Interventional Results available

Multicenter Hologic Tomosynthesis Study

NCT00971087
View directory record Official record
Conditions
Breast Cancer
Interventions
Hologic Selenia Dimensions Digital Breast Tomosynthesis System
Device
Lead sponsor
Hologic, Inc.
Industry
Eligibility
18 Years to 110 Years · Female only
Enrollment
3,521 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
22
States / cities
Scottsdale, Arizona • Newport Beach, California • Sacramento, California + 19 more
Source: ClinicalTrials.gov public record
Updated Feb 26, 2025 · Synced Oct 21, 2026, 10:42 PM EDT