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ClinicalTrials.gov public records Last synced Nov 3, 2026, 2:04 AM EST

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Showing 97–120 of 163 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Breathing Exercise Clear all
Completed No phase listed Observational

Study of Exercise and Heart Function in Patients With Heart Failure and Pulmonary Vascular Disease

NCT01418248
View directory record Official record
Conditions
Exercise Tolerance, Dyspnea, Heart Failure, Pulmonary Hypertension
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 9, 2014 · Synced Nov 3, 2026, 2:04 AM EST
Completed Not applicable Interventional Results available

Leg Exercise During ECMO

NCT03135210
View directory record Official record
Conditions
Refractory Respiratory Failure
Interventions
Open-Chain Leg Exercise, Closed-Chain Leg Exercise
Other · Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 70 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 21, 2021 · Synced Nov 3, 2026, 2:04 AM EST
Completed Not applicable Interventional

Augmenting a Post-Stroke Wellness Program With Respiratory Muscle Training

NCT05819333
View directory record Official record
Conditions
Stroke
Interventions
Exercise Program + Respiratory Strength Training, Exercise Program + Respiratory Relaxation Training
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 95 Years
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Nov 3, 2026, 2:04 AM EST
Completed Not applicable Interventional

Respiratory Muscle Training in L-Onset Pompe Disease (LOPD)

NCT02801539
View directory record Official record
Conditions
Glycogen Storage Disease Type II
Interventions
RMT therapy using modified RMT device, Sham-RMT therapy using modified RMT device
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 30, 2019 · Synced Nov 3, 2026, 2:04 AM EST
Terminated Not applicable Interventional Results available

Impact of Respiratory Training in Lymphoma Survivors

NCT05938127
View directory record Official record
Conditions
Hodgkin Lymphoma, Non Hodgkin Lymphoma
Interventions
Inspiratory muscle strength training, Sham Inspiratory muscle strength training
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 80 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
2
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Nov 3, 2026, 2:04 AM EST
Completed Phase 3 Interventional Results available

To Evaluate the Effect of Inhaled Medication Together With Exercise and Activity Training on Exercise Capacity and Daily Activities in Patients With Chronic Lung Disease With Obstruction of Airways

NCT02085161
View directory record Official record
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
placebo to tiotropium + olodaterol, tiotropium +olodaterol, tiotropium
Drug
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
40 Years to 75 Years
Enrollment
304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
3
States / cities
San Diego, California • Torrance, California • Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 6, 2017 · Synced Nov 3, 2026, 2:04 AM EST
Recruiting Phase 1Phase 2 Interventional

Low-Tech Treatments for Obstructive Sleep Apnea

NCT07301710
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA), Traumatic Brain Injury (TBI)
Interventions
High-Resistance Breathing and Drinking Exercises, Low-Resistance Breathing and Drinking Exercises
Behavioral
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Nov 3, 2026, 2:04 AM EST
Enrolling by invitation Not applicable Interventional

Targeted Prehabilitation With Physical Exercise and Inspiratory Muscle Training for Elderly Frail Patients Prior to Ventral Hernia Repair

NCT06874413
View directory record Official record
Conditions
Frailty, Ventral Hernia
Interventions
Prehabilitation, Standard of Care (SOC)
Behavioral · Other
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
65 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Nov 3, 2026, 2:04 AM EST
Completed Not applicable Interventional

Reducing Sedentary Behavior to Improve Sleep: an Ancillary Study to the RESET BP Clinical Trial

NCT03946228
View directory record Official record
Conditions
Sleep, Obstructive Sleep Apnea, Insomnia
Interventions
Behavioral Intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
21 Years to 65 Years
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 7, 2023 · Synced Nov 3, 2026, 2:04 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

Leveraging Exercise Stress Echocardiography for Heart Failure With Preserved Ejection Fraction

NCT06927973
View directory record Official record
Conditions
Chest Pain, Shortness of Breath
Interventions
Echocardiogram
Diagnostic Test
Lead sponsor
Duke University
Other
Eligibility
50 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Nov 3, 2026, 2:04 AM EST
Not yet recruiting Not applicable Interventional

Inspiratory Muscle Strength Training in Adults With Type 1 Diabetes

NCT07859943
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
High-Resistance Inspiratory Muscle Strength Training, Sham Inspiratory Muscle Strength Training
Device
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 35 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
2
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Nov 3, 2026, 2:04 AM EST
Completed Phase 2 Interventional

Nitric Oxide Inhalation Therapy to Relieve Chest Pain in Patients With Coronary Artery Disease

NCT00014040
View directory record Official record
Conditions
Coronary Disease, Myocardial Ischemia
Interventions
Nitric Oxide and INOpulse Delivery System
Drug
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
Not listed
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2003
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Nov 3, 2026, 2:04 AM EST
Active, not recruiting No phase listed Observational

Measuring Outcomes of Activity in Intensive Care

NCT03115840
View directory record Official record
Conditions
Critical Illness, Sepsis, Mechanical Ventilation, Physical Activity, Disability Physical, Muscle Weakness, Cognitive Impairment
Interventions
Not listed
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
312 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2030
U.S. locations
2
States / cities
Columbus, Ohio • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Nov 3, 2026, 2:04 AM EST
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Effects of Tiotropium on Breathing Capacity and Exercise Limitation in Early Stages of Chronic Obstructive Pulmonary Disease

NCT01072396
View directory record Official record
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
Tiotropium, Placebo
Drug
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
40 Years and older
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
11
States / cities
Birmingham, Alabama • Jasper, Alabama • Torrance, California + 8 more
Source: ClinicalTrials.gov public record
Updated Dec 24, 2013 · Synced Nov 3, 2026, 2:04 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

Covid-19 Virtual Recovery Study

NCT04950725
View directory record Official record
Conditions
Covid19
Interventions
Strength RMT, Strength RMT and nasal breathing, Endurance RMT, Endurance RMT and nasal breathing, Low dose RMT
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
2,268 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 21, 2023 · Synced Nov 3, 2026, 2:04 AM EST
Completed Phase 2 Interventional

Inhaled Iloprost in Adults With Abnormal Pulmonary Pressure and Associated With Idiopathic Pulmonary Fibrosis

NCT00109681
View directory record Official record
Conditions
Pulmonary Fibrosis, Pulmonary Hypertension
Interventions
Iloprost Inhalation Solution (Ventavis)
Drug
Lead sponsor
Actelion
Industry
Eligibility
40 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
17
States / cities
Birmingham, Alabama • Los Angeles, California • San Diego, California + 14 more
Source: ClinicalTrials.gov public record
Updated Feb 15, 2010 · Synced Nov 3, 2026, 2:04 AM EST
Completed Not applicable Interventional Results available

Effects of a Walking Program and Inspiratory Muscle Training in Individuals With Chronic Heart Failure

NCT01560871
View directory record Official record
Conditions
Heart Failure NYHA Class II, Heart Failure NYHA Class III
Interventions
High-intensity IMT plus walking, Low-intensity IMT plus walking
Behavioral
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 90 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
2
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Nov 3, 2026, 2:04 AM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy Study of Mindfulness-Based Exercise for Posttraumatic Stress Disorder (PTSD)

NCT01462045
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Mindfulness-based exercise
Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
21 Years and older
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Jan 6, 2015 · Synced Nov 3, 2026, 2:04 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

Lifestyle Interventions for Seniors With Apnea

NCT01422863
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Lifestyle Intervention
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
60 Years to 75 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 18, 2017 · Synced Nov 3, 2026, 2:04 AM EST
Completed Phase 3 Interventional Results available

A Study to Determine the Effect of Tiotropium + Olodaterol Fixed Dose Combination on Exercise Endurance Time During Constant Work Rate Cycle Ergometry Test in COPD

NCT01525615
View directory record Official record
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
Respimat inhaler, tiotropium+olodaterol (low dose), tiotropium + olodaterol (high dose), placebo to tiotropium+olodaterol
Device · Drug
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
40 Years to 75 Years
Enrollment
404 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
15
States / cities
Torrance, California • Hartford, Connecticut • Springfield, Illinois + 12 more
Source: ClinicalTrials.gov public record
Updated Aug 29, 2016 · Synced Nov 3, 2026, 2:04 AM EST
Completed Not applicable Interventional

Inspiratory Muscle Training Post-Liver Transplant

NCT03130608
View directory record Official record
Conditions
Liver Disease Chronic, Muscle Weakness, Respiratory Insufficiency
Interventions
Inspiratory Muscle Training
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 21, 2021 · Synced Nov 3, 2026, 2:04 AM EST
Completed No phase listed Observational

Modifying Exercise for the COPD Patient

NCT02143206
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease, Arthritis, Pain
Interventions
Not listed
Lead sponsor
Angela N Fellner PhD CCRP
Other
Eligibility
18 Years to 99 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 22, 2018 · Synced Nov 3, 2026, 2:04 AM EST
Not listed Not applicable Interventional

Impact of Customized Respiratory Training on Cardiopulmonary Function in Parkison's Disease

NCT05287243
View directory record Official record
Conditions
Parkinson Disease
Interventions
inspiratory muscle training
Other
Lead sponsor
University of St. Augustine for Health Sciences
Other
Eligibility
30 Years to 99 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated May 9, 2023 · Synced Nov 3, 2026, 2:04 AM EST
Terminated Phase 2 Interventional Results available

Acute Effects of Inhaled Treprostinil in Fontan Patients

NCT02769624
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
Treprostinil, Placebo
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 29, 2020 · Synced Nov 3, 2026, 2:04 AM EST