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ClinicalTrials.gov public records Last synced Nov 3, 2026, 11:59 AM EST

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Showing 145–163 of 163 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Breathing Exercise Clear all
Recruiting Not applicable Interventional

Functional Improvement in OSA and COPD With a Telehealth LifeStyle and Exercise Intervention

NCT06390345
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease, Obstructive Sleep Apnea, Overweight and Obesity
Interventions
FOCuSEd Integrated Intervention, Enhanced Usual Care
Other
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
5
States / cities
Boise, Idaho • Chicago, Illinois • Minneapolis, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Nov 3, 2026, 11:59 AM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparing Nose & Mouth Breathing During Exercise

NCT05702047
View directory record Official record
Conditions
Healthy
Interventions
Nose-only breathing, Mouth-only breathing
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 30 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Nov 15, 2024 · Synced Nov 3, 2026, 11:59 AM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study Will Test the Theory That Training With the Facial-Flex Exercise Device Will Improve Snoring in Patients

NCT01554904
View directory record Official record
Conditions
Primary Snoring, Sleep Apnea
Interventions
Facial-Flex
Device
Lead sponsor
Facial Concepts, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 1, 2013 · Synced Nov 3, 2026, 11:59 AM EST
Completed Not applicable Interventional

Pranayama Breathing and Uncontrolled Hypertension

NCT03320577
View directory record Official record
Conditions
Uncontrolled Hypertension
Interventions
Class instruction of breathing exercises, DVD instruction of breathing exercises, Control
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
22 Years and older
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 10, 2023 · Synced Nov 3, 2026, 11:59 AM EST
Completed Phase 2 Interventional Results available

Fentanyl Pectin Nasal Spray (FNPS) for Exercise-Induced Breakthrough Dyspnea

NCT01832402
View directory record Official record
Conditions
Advanced Cancers
Interventions
Fentanyl Pectin Nasal Spray, Placebo Nasal Spray, Walk Test, Questionnaires, Mental Ability Tests
Drug · Other · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 8, 2023 · Synced Nov 3, 2026, 11:59 AM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

A Study Of Resilience And Mental Well-Being Through Breathing Practice For Clinical Care Professionals

NCT07218458
View directory record Official record
Conditions
Burnout, Healthcare Workers, Breathing Exercises
Interventions
Structured Breathing
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
4
States / cities
Albert Lea, Minnesota • Mankato, Minnesota • Eau Claire, Wisconsin + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 2, 2026 · Synced Nov 3, 2026, 11:59 AM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Breathing Training and Nitrate on Exercise at Simulated Altitude

NCT07216755
View directory record Official record
Conditions
Healthy Adults, Mechanical Ventilation Dependence, Hypoxia, Exercise Training, Exercise Intolerance, Dietary Supplement, Nitrate Supplementation, Inspiratory Muscle Training
Interventions
Respiratory Muscle Training (RMT), Sham Respiratory Muscle Training, Dietary Supplement: Beetroot Juice Concentrate, placebo beverage
Device · Dietary Supplement
Lead sponsor
Embry-Riddle Aeronautical University
Other
Eligibility
18 Years to 40 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Daytona Beach, Florida
Source: ClinicalTrials.gov public record
Updated Oct 15, 2025 · Synced Nov 3, 2026, 11:59 AM EST
Recruiting Phase 1Phase 2 Interventional

Low-Tech Treatments for Obstructive Sleep Apnea

NCT07301710
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA), Traumatic Brain Injury (TBI)
Interventions
High-Resistance Breathing and Drinking Exercises, Low-Resistance Breathing and Drinking Exercises
Behavioral
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Nov 3, 2026, 11:59 AM EST
Completed Phase 1 Interventional

Inspiratory Muscle Training in Ventilator Dependent Patients

NCT00419458
View directory record Official record
Conditions
Failure to Wean, Respiratory Failure, Ventilator Dependent
Interventions
inspiratory muscle strength training
Procedure
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
16 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 9, 2009 · Synced Nov 3, 2026, 11:59 AM EST
Terminated No phase listed Observational Accepts healthy volunteers

Myocardial Performance at Rest and During Exercise in Heart Failure With Preserved Ejection Fraction

NCT01747785
View directory record Official record
Conditions
Heart Failure
Interventions
Cardiac rehabilitation, Myocardial deformation imaging, Cardiopulmonary exercise test
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
La Crosse, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 17, 2016 · Synced Nov 3, 2026, 11:59 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

Breathing Regulation Training for Individuals With Panic Disorder

NCT00183521
View directory record Official record
Conditions
Panic Disorder
Interventions
Raise-CO2 breathing regulation training, Lower-CO2 breathing regulation training, Control
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 60 Years
Enrollment
136 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Dec 2, 2011 · Synced Nov 3, 2026, 11:59 AM EST
Completed Phase 3 Interventional

Ventilatory Muscle Training in Stroke

NCT02828943
View directory record Official record
Conditions
Stroke, Pulmonary Ventilation, Exercise Therapy
Interventions
IMT with High Resistance EMT, IMT with Low Resistance EMT
Behavioral
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 17, 2019 · Synced Nov 3, 2026, 11:59 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

This Study Explores Whether Adding Natural Elements Like Plants and Sunlight to Indoor Gyms Makes Exercise Feel Easier, More Enjoyable, and Improves Performance. By Comparing Workouts in Nature-inspired and Plain Gym Settings, it Aims to Find Better Ways to Design Fitness Spaces in Cities.

NCT06928311
View directory record Official record
Conditions
Biophilic Environmental Design, Traditional Exercise Design
Interventions
Exercise Environment
Other
Lead sponsor
Colorado State University
Other
Eligibility
18 Years to 25 Years · Male only
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Nov 3, 2026, 11:59 AM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy Study of Mindfulness-Based Exercise for Posttraumatic Stress Disorder (PTSD)

NCT01462045
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Mindfulness-based exercise
Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
21 Years and older
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Jan 6, 2015 · Synced Nov 3, 2026, 11:59 AM EST
Completed Phase 3 Interventional Results available

To Evaluate the Effect of Inhaled Medication Together With Exercise and Activity Training on Exercise Capacity and Daily Activities in Patients With Chronic Lung Disease With Obstruction of Airways

NCT02085161
View directory record Official record
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
placebo to tiotropium + olodaterol, tiotropium +olodaterol, tiotropium
Drug
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
40 Years to 75 Years
Enrollment
304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
3
States / cities
San Diego, California • Torrance, California • Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 6, 2017 · Synced Nov 3, 2026, 11:59 AM EST
Completed No phase listed Observational

Effect of Nasal CPAP on Cardiopulmonary Exercise Testing in Patients With Overlap Syndrome

NCT01033266
View directory record Official record
Conditions
Obstructive Sleep Apnea, Chronic Obstructive Pulmonary Disease
Interventions
CPET
Diagnostic Test
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
2
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 14, 2020 · Synced Nov 3, 2026, 11:59 AM EST
Completed Phase 2 Interventional Results available

Feasibility of Home-based Exercise Program for Adults With Cystic Fibrosis

NCT05239611
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
Xenon MRI
Diagnostic Test
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Nov 3, 2026, 11:59 AM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of High Velocity/Hyperoxic Breathing Therapy on Blood Lactate Decline

NCT05984186
View directory record Official record
Conditions
Dyspnea, Lactic Acidosis, Muscle, Breathlessness, Exercise, Recovery
Interventions
High Velocity Therapy
Device
Lead sponsor
Vapotherm, Inc.
Industry
Eligibility
18 Years to 30 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 8, 2024 · Synced Nov 3, 2026, 11:59 AM EST
Completed Phase 2 Interventional

Effect of Ventilation-Feedback Training on Exercise Performance in COPD

NCT00037973
View directory record Official record
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
ventilation feedback, exercise
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
40 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2003
U.S. locations
1
States / cities
Hines, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 16, 2010 · Synced Nov 3, 2026, 11:59 AM EST