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Showing 1–24 of 161 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Breathing Exercises Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Sleep Apnea, Cardiovascular and Exercise Study

NCT03219749
View directory record Official record
Conditions
Obstructive Sleep Apnea, Vascular Diseases, Obesity
Interventions
exercise training
Behavioral
Lead sponsor
Towson University
Other
Eligibility
30 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Towson, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 9, 2019 · Synced Sep 3, 2026, 2:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

High Altitude and Exogenous Carbohydrate Oxidation

NCT03851744
View directory record Official record
Conditions
Glucose Metabolism, High Altitude
Interventions
Sea Level, High Altitude
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 39 Years · Male only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 1, 2021 · Synced Sep 3, 2026, 2:13 PM EDT
Terminated Not applicable Interventional Results available

A Randomized Control Trial Treating Depression With Yoga and Coherent Breathing Versus Walking in Veterans

NCT03489122
View directory record Official record
Conditions
Depressive Disorder, Major, Post Traumatic Stress Disorder
Interventions
yoga, walking
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Bedford, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 10, 2025 · Synced Sep 3, 2026, 2:13 PM EDT
Completed Phase 3 Interventional Results available

Effect on Exercise Endurance and Lung Hyperinflation of Tiotropium + Olodaterol in COPD Patients.

NCT01533935
View directory record Official record
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
Placebo, tiotropium + Olodaterol, Tiotropium, Olodaterol, Respimat
Drug · Device
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
40 Years to 75 Years
Enrollment
291 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
11
States / cities
Phoenix, Arizona • Austell, Georgia • Baltimore, Maryland + 8 more
Source: ClinicalTrials.gov public record
Updated Sep 14, 2015 · Synced Sep 3, 2026, 2:13 PM EDT
Completed Phase 3 Interventional

Ventilatory Muscle Training in Stroke

NCT02828943
View directory record Official record
Conditions
Stroke, Pulmonary Ventilation, Exercise Therapy
Interventions
IMT with High Resistance EMT, IMT with Low Resistance EMT
Behavioral
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 16, 2019 · Synced Sep 3, 2026, 2:13 PM EDT
Completed No phase listed Observational

Sleep Apnea in Heart Failure With Preserved Ejection Fraction

NCT05008432
View directory record Official record
Conditions
Heart Failure, Obstructive Sleep Apnea
Interventions
Home sleep apnea testing
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 99 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 27, 2024 · Synced Sep 3, 2026, 2:13 PM EDT
Completed No phase listed Observational

Effect of Nasal CPAP on Cardiopulmonary Exercise Testing in Patients With Overlap Syndrome

NCT01033266
View directory record Official record
Conditions
Obstructive Sleep Apnea, Chronic Obstructive Pulmonary Disease
Interventions
CPET
Diagnostic Test
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
2
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 13, 2020 · Synced Sep 3, 2026, 2:13 PM EDT
Recruiting Not applicable Interventional

Combined Respiratory Training in Persons With ALS

NCT05913882
View directory record Official record
Conditions
ALS, Respiratory Insufficiency, Dysphagia
Interventions
Respiratory Muscle Strength Training (LVR+EMST)
Device
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 90 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Sep 3, 2026, 2:13 PM EDT
Completed Phase 2 Interventional

Nurse Managed Upper Body Strength Training in Chronic Obstructive Pulmonary Disease (COPD)

NCT01057797
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Exercise-specific self-efficacy, Gentle chair exercise, upper body strength training
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
45 Years and older
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 26, 2010 · Synced Sep 3, 2026, 2:13 PM EDT
Recruiting Not applicable Interventional

Effect of Inspiratory Muscle Training on Physiological Function and Clinical Outcomes After Lung Transplant

NCT04783155
View directory record Official record
Conditions
Post-Lung Transplantation Bronchiectasis
Interventions
POWERBreathe Plus®, Cardiopulmonary rehabilitation post lung transplant
Device · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 5, 2026 · Synced Sep 3, 2026, 2:13 PM EDT
Recruiting Phase 2 Interventional

Respiratory Muscle Training Before Surgery in Preventing Lung Complications in Patients With Stage I-IIIB Lung Cancer

NCT04067830
View directory record Official record
Conditions
Stage I Lung Cancer AJCC v8, Stage IA1 Lung Cancer AJCC v8, Stage IA2 Lung Cancer AJCC v8, Stage IA3 Lung Cancer AJCC v8, Stage IB Lung Cancer AJCC v8, Stage II Lung Cancer AJCC v8, Stage IIA Lung Cancer AJCC v8, Stage IIB Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8
Interventions
Best Practice, Laparoscopic Surgery, Quality-of-Life Assessment, Questionnaire Administration, Respiratory Muscle Training Device, Video-Assisted Thoracic Surgery
Other · Procedure · Device
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 3, 2026, 2:13 PM EDT
Recruiting Not applicable Interventional

Inclined Versus Standard Exercise for COPD Patients

NCT06749262
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
walking on incline or walking at increasing speed for 36 visits
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
45 Years to 80 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 3, 2026, 2:13 PM EDT
Completed No phase listed Observational Results available

BRAIN, Symptoms, and Physical Activity in COPD

NCT04291131
View directory record Official record
Conditions
COPD, Chronic Musculoskeletal Pain
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years and older · Male only
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 14, 2025 · Synced Sep 3, 2026, 2:13 PM EDT
Completed Not applicable Interventional Results available

Innovation in Pulmonary Rehabilitation

NCT00123422
View directory record Official record
Conditions
Pulmonary Disease, Pulmonary Emphysema
Interventions
Breathing retraining, Heliox, Exercise
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
40 Years and older
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Hines, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 15, 2014 · Synced Sep 3, 2026, 2:13 PM EDT
Completed Not applicable Interventional

Project 4B: Lower Extremity Strength Training in ICU Patients

NCT02467023
View directory record Official record
Conditions
Sepsis
Interventions
Muscle stimulation with Niveus medical stimulator, measurement of maximal isometric twitch strength, Muscle Biopsy, Muscle Biopsy Medication: Lidocaine, Muscle Biopsy Medication: Versed, Muscle Biopsy Medication: Fentanyl, Blood and Urine Sampling, ineffective muscle stimulation
Device · Procedure · Drug + 1 more
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 18, 2018 · Synced Sep 3, 2026, 2:13 PM EDT
Not listed No phase listed Observational

Gas Exchange for Predicting Hospital Heart Failure Readmissions

NCT01960218
View directory record Official record
Conditions
Acute Decompensated Heart Failure
Interventions
Not listed
Lead sponsor
Shape Medical Systems, Inc.
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
7
States / cities
Washington D.C., District of Columbia • Champaign, Illinois • Boston, Massachusetts + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 3, 2014 · Synced Sep 3, 2026, 2:13 PM EDT
Completed No phase listed Observational

EMPOWER-PULM (PULMonary Outcomes in Older Adults Empowered With Movement to Prevent Obesity and Weight Regain)

NCT03621098
View directory record Official record
Conditions
Obesity, Pulmonary Disease, Dyspnea
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years to 85 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 5, 2019 · Synced Sep 3, 2026, 2:13 PM EDT
Completed Not applicable Interventional Results available

Respiratory Muscle Training (RMT) in ALS

NCT04224961
View directory record Official record
Conditions
ALS
Interventions
Respiratory Muscle Training
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Sep 3, 2026, 2:13 PM EDT
Not listed Not applicable Interventional

Impact of Customized Respiratory Training on Cardiopulmonary Function in Parkison's Disease

NCT05287243
View directory record Official record
Conditions
Parkinson Disease
Interventions
inspiratory muscle training
Other
Lead sponsor
University of St. Augustine for Health Sciences
Other
Eligibility
30 Years to 99 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated May 8, 2023 · Synced Sep 3, 2026, 2:13 PM EDT
Completed Phase 2 Interventional

Inhaled Iloprost, Dynamic Hyperinflation, and Oxidative Stress in COPD Patients

NCT01941225
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Inhaled iloprost 5.0 mcg, Placebo
Drug
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
40 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Dec 15, 2016 · Synced Sep 3, 2026, 2:13 PM EDT
Completed No phase listed Observational

Study of Exercise and Heart Function in Patients With Heart Failure and Pulmonary Vascular Disease

NCT01418248
View directory record Official record
Conditions
Exercise Tolerance, Dyspnea, Heart Failure, Pulmonary Hypertension
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 8, 2014 · Synced Sep 3, 2026, 2:13 PM EDT
Not listed Not applicable Interventional

Walking and Blood Pressure in Older Adults With Respiratory Impairment.

NCT06033417
View directory record Official record
Conditions
Respiratory Impairment, Elevated Blood Pressure, Physical Inactivity
Interventions
Increased lifestyle walking (intervention), Health education only (control)
Other
Lead sponsor
Iowa State University
Other
Eligibility
65 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Ames, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 12, 2023 · Synced Sep 3, 2026, 2:13 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Three New Ideas to Protect Special Forces From the Stress of High Altitude

NCT02463357
View directory record Official record
Conditions
Mountain Sickness
Interventions
Quercetin, Nifedipine extended release, Methazolamide, Metformin, Placebo, Nitrite
Dietary Supplement · Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Alma, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 29, 2021 · Synced Sep 3, 2026, 2:13 PM EDT
Completed Phase 2 Interventional Results available

Effect of iNO on Invasively Derived Pulmonary Pressures in Patients With PAH

NCT02734953
View directory record Official record
Conditions
Pulmonary Arterial Hypertension
Interventions
Nitric Oxide
Drug
Lead sponsor
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Other
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 23, 2018 · Synced Sep 3, 2026, 2:13 PM EDT