- Conditions
- Age-related Macular Degeneration, Age-related Maculopathy
- Interventions
- Observational-1, Observational-2
- Other
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 49 Years and older
- Enrollment
- 603 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2027
- U.S. locations
- 2
- States / cities
- Los Angeles, California • Pittsburgh, Pennsylvania
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Showing 25–48
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- Conditions
- PTSD, Sleep, Obstructive Sleep Apnea, Quality of Life
- Interventions
- Not listed
- Lead sponsor
- Veterans Medical Research Foundation
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 59 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Sleep Related Breathing Disorder, Snoring, Obstructive Sleep Apnea (OSA), Open Bite, Occlusal Changes, Tooth Migration, Posterior Open Bite
- Interventions
- AM Aligner, Exercise
- Device · Behavioral
- Lead sponsor
- Isabel Moreno Hay
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Lexington, Kentucky
- Conditions
- Diabetes Mellitus, Hypertension, Metabolic Disease, Obesity, Sleep Apnea Syndrome
- Interventions
- Orlistat, Placebo
- Drug
- Lead sponsor
- Jack Yanovski
- NIH
- Eligibility
- 12 Years to 17 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1998 – 2011
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- Pregnancy Related, Sleep Disordered Breathing, Obesity
- Interventions
- Not listed
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 20 Years to 39 Years · Female only
- Enrollment
- 19 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Sleep Related Breathing Disorder, Congestive Heart Failure
- Interventions
- CRT with atrial overdrive pacing
- Device
- Lead sponsor
- VA Pittsburgh Healthcare System
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 19 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2008
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Recurrent Tonsillitis, Obstructive Sleep Apnea, Sleep Disordered Breathing, Adverse Reaction to Drug
- Interventions
- Ibuprofen, Hydrocodone-Acetaminophen
- Drug
- Lead sponsor
- Emory University
- Other
- Eligibility
- 4 Years to 17 Years
- Enrollment
- 45 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
- Conditions
- Obstructive Sleep Apnea, PTSD, Posttraumatic Stress Disorder
- Interventions
- CBT-OSA, Sleep Education
- Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 76 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2023
- U.S. locations
- 1
- States / cities
- Palo Alto, California
- Conditions
- Pregnancy Complicated by Cardiovascular Disorders as Postpartum Condition, Delivered During Previous Episode, Breathing-Related Sleep Disorder
- Interventions
- Not listed
- Lead sponsor
- RTI International
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 4,509 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2020
- U.S. locations
- 15
- States / cities
- Fountain Valley, California • Long Beach, California • Orange, California + 10 more
- Conditions
- Cardiopulmonary Failure, Myocardial Infarction (MI), Heart Decompensation, Heart Failure, HFrEF - Heart Failure with Reduced Ejection Fraction, HFpEF - Heart Failure with Preserved Ejection Fraction, Syncopation, Syncope, Ischemic Cardiovascular Disease, STEMI, STEMI (ST Elevation MI), Atrial Fibrillation (AF), Atrial Enlargement, LVF, Conduction Defect, Conduction Abnormalities, Heart Block, Valvular Diseases, Cardiac Output, Low, Stroke Volume, Stroke Volume Variation, Hyperkalemia, Hypercalcemia, Hypocalcemia, LV Dysfunction, QT Prolongation, Sudden Cardiac Death Due to Cardiac Arrhythmia, Ventricular Arrhythmia, Pacing, Pacing Induced Dyssynchrony, Silent Ischemia, Pericarditis, Sleep Related Breathing Disorder, RSA, Apnea, Obstructive, Cardiac Output Measurement, Respiratory Impedance, CRT And/or ICD, Infarction, Cardiomyopathies, Primary, Hypertrophy
- Interventions
- SUBPROTOCOL A, SUBPROTOCOL B, SUBPROTOCOL C, SUBPROTOCOL D, SUBPROTOCOL E, SUBPROTOCOL F, SUBPROTOCOL G, SUBPROTOCOL H
- Device
- Lead sponsor
- Peerbridge Health, Inc
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 15,000 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Melbourne, Florida
- Conditions
- Obstructive Sleep Apnea
- Interventions
- CPAP, MAD
- Device
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 42 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2017
- U.S. locations
- 1
- States / cities
- Buffalo, New York
- Conditions
- Sleep Apnea, Obstructive
- Interventions
- Continuous Positive Airway Pressure (CPAP)
- Device
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 144 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2006 – 2011
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Obstructive Sleep Apnea, Fetal Growth Restriction, Pregnancy Related
- Interventions
- S9 VPAP Adapt
- Device
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 18 Years to 50 Years · Female only
- Enrollment
- 3 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 2
- States / cities
- St Louis, Missouri • Rochester, New York
- Conditions
- Sleep Apnea Syndromes, Insomnia Disorder, Stress Disorders, Post-Traumatic
- Interventions
- Apnea and Insomnia Relief (AIR), Sleep Education (SE)
- Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2025
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Periodic Fever, Aphthous Stomatitis, Pharyngitis, And Cervical Adenitis (Pfapa), Obstructive Sleep Apnea, Tonsillitis, Tonsil Disorder, Sleep Disordered Breathing
- Interventions
- Not listed
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Eligibility
- 1 Month to 99 Years
- Enrollment
- 1,500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2038
- U.S. locations
- 3
- States / cities
- Washington D.C., District of Columbia • Indianapolis, Indiana • Bethesda, Maryland
- Conditions
- Sleep Apnea, Obstructive, Obesity
- Interventions
- Propofol Alone, Propofol+Benzo/Opioids
- Drug
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2014
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Obstructive Sleep Apnea, Hypercapnia, Spinal Cord Injury
- Interventions
- BiPAP, BiPAP/AVAPS (Phillips Respironics)
- Device
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 93 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2016
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Asthma Control, Pulmonary Function, Quality of Life, Stress, Sleep Quality
- Interventions
- Energy Recovery Ventilator, Portable Air Cleaner, Energy Recovery Ventilator (Sham), Portable Air Cleaner (Sham)
- Device
- Lead sponsor
- The University of Texas at Arlington
- Other
- Eligibility
- 5 Years and older
- Enrollment
- 80 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 2
- States / cities
- Arlington, Texas • Plano, Texas
- Conditions
- Sleep Disorder; Breathing-Related
- Interventions
- Standard of Care, Mask Advice Tool
- Other
- Lead sponsor
- Philips Respironics
- Industry
- Eligibility
- 21 Years to 85 Years
- Enrollment
- 310 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2020
- U.S. locations
- 5
- States / cities
- Kissimmee, Florida • Chevy Chase, Maryland • Youngstown, Ohio + 2 more
- Conditions
- Diabetic Retinopathy, Macular Degeneration, Glaucoma, Retinitis Pigmentosa, Vision Disorders, Acute Coronary Syndrome, Implantable Defibrillator User, Congestive Heart Failure, Hypertrophic Obstructive Cardiomyopathy, Orthostatic Hypotension, Syncope, Presyncope, Narcolepsy, Dementia, Multiple Sclerosis, Parkinson Disease, Brain Injuries, Spinal Cord Injuries, Stroke, Vertigo, Dizziness, Seizures, Substance Use, Insulin Dependent Diabetes Mellitus, Arthritis, Foot--Abnormalities, Chronic Obstructive Pulmonary Disease, Obstructive Sleep Apnea, End Stage Renal Disease, Sleep Apnea, Insomnia, Restless Legs Syndrome
- Interventions
- Driving Decision Aid, Older Drivers Website
- Behavioral
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 529 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2023
- U.S. locations
- 3
- States / cities
- La Jolla, California • Aurora, Colorado • Indianapolis, Indiana
- Conditions
- Obstructive Sleep Apnea Syndrome, Cleft Lip/Palate
- Interventions
- Not listed
- Lead sponsor
- University of Rochester
- Other
- Eligibility
- 1 Year to 18 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2009
- U.S. locations
- 1
- States / cities
- Rochester, New York
- Conditions
- Sleep Apnea, Age
- Interventions
- 1) hyperventilation via noninvasive positive pressure ventilation 2) multiple trials of episodic hypoxia
- Other
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years to 89 Years
- Enrollment
- 92 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2015
- U.S. locations
- 1
- States / cities
- Detroit, Michigan
- Conditions
- Obstructive Sleep Apnea, Pregnancy Related, Insulin Sensitivity
- Interventions
- Continuous Positive Airway Pressure
- Device
- Lead sponsor
- Barnes-Jewish Hospital
- Other
- Eligibility
- 20 Years to 39 Years · Female only
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Burnout, Professional, Stress, Psychological, Stress, Physiological, Psychological Well-Being, Mind-Body Therapies, Work Related Stress
- Interventions
- Sudarshan Kriya Yoga (SKY) Breathing and Sahaj Meditation, Health Education Program (HEP)
- Behavioral · Other
- Lead sponsor
- Lancaster General Hospital
- Other
- Eligibility
- 25 Years to 70 Years
- Enrollment
- 180 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2026
- U.S. locations
- 6
- States / cities
- Boston, Massachusetts • Plainsboro, New Jersey • Lancaster, Pennsylvania + 1 more