- Conditions
- Postoperative Pain
- Interventions
- HTX-011, Luer Lock applicator, Vial access device, aprepitant
- Drug · Device
- Lead sponsor
- Heron Therapeutics
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 78 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
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Showing 25–48
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- Conditions
- Hyperpronated Foot, Reconstruction Surgeries of the Foot, Fixation of Fractures and Fusion (Bunionectomy Osteotomies) of the Foot/Ankle, Fixation of Small Bone Fragments of the Foot/Ankle, Lisfranc Arthrodesis, Mono or Bi-cortical Osteotomies in the Forefoot, First Metatarsophalangeal Arthrodesis, Akin Osteotomy, Midfoot and Hindfoot Arthrodeses or Osteotomies, Fixation of Osteotomies for Hallux Valgus Treatment (Scarf and Chevron), Arthrodesis of the Metatarsocuneiform Joint to Reposition and Stabilize Metatarsus Primus Varus, Osteotomy Fixation of Hallux Valgus Repair (Such as Scarf and Chevron Etc.), Medial Ankle Stabilization, Tibiotalocalcaneal Arthrodesis
- Interventions
- Products listed in Group/Cohort Description
- Device
- Lead sponsor
- Arthrex, Inc.
- Industry
- Eligibility
- 2 Years and older
- Enrollment
- 700 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2027
- U.S. locations
- 5
- States / cities
- Sacramento, California • Chicago, Illinois • Nashville, Tennessee + 2 more
- Conditions
- Pain, Post-operative
- Interventions
- N1539, Intravenous Placebo
- Drug
- Lead sponsor
- Baudax Bio
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 59 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015
- U.S. locations
- 1
- States / cities
- Pasadena, Maryland
- Conditions
- Hallux Valgus, Bunionectomy
- Interventions
- ALX006 (bupivacaine extended-release injection), Bupivacaine Hcl 0.25% Inj, Sciatic Nerve Block
- Drug · Procedure
- Lead sponsor
- Rebel Medicine Inc
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 1
- States / cities
- Millcreek, Utah
- Conditions
- Postoperative Pain
- Interventions
- Pregabalin, Acetaminophen, Placebo 1, Placebo 2
- Drug · Other
- Lead sponsor
- Nevakar, Inc.
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 87 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020
- U.S. locations
- 2
- States / cities
- Pasadena, California • Bellaire, Texas
- Conditions
- Pain, Postoperative, Bunion
- Interventions
- COV795, Placebo
- Drug
- Lead sponsor
- Mallinckrodt
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 329 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 5
- States / cities
- Bakersfield, California • Pasadena, California • Pasadena, Maryland + 2 more
- Conditions
- Pain, Post-surgical
- Interventions
- valdecoxib, valdecoxib/placebo, placebo
- Drug
- Lead sponsor
- Pfizer
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 360 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2002 – 2003
- U.S. locations
- 21
- States / cities
- Phoenix, Arizona • Tempe, Arizona • Anaheim, California + 10 more
- Conditions
- Pain
- Interventions
- CA-008, Ketorolac, Acetaminophen IV, Fentanyl, Bupivacaine Hydrochloride, Lidocaine HCl, Celecoxib, Acetaminophen Oral, Lidocaine Hydrochloride, Exparel
- Drug
- Lead sponsor
- Concentric Analgesics
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019
- U.S. locations
- 1
- States / cities
- Pasadena, California
- Conditions
- Acute Pain
- Interventions
- VX-993, HB/APAP, Placebo (matched to VX-993), Placebo (matched to HB/APAP)
- Drug
- Lead sponsor
- Vertex Pharmaceuticals Incorporated
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 367 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 14
- States / cities
- Sheffield, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 11 more
- Conditions
- Bunionectomy, Pain, Postoperative Pain, Acute Pain
- Interventions
- CG5503 IR, Morphine, Placebo
- Drug
- Lead sponsor
- Grünenthal GmbH
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 291 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2008
- U.S. locations
- 6
- States / cities
- Pasadena, Maryland • Austin, Texas • Houston, Texas + 3 more
- Conditions
- Bunions, Postoperative Pain
- Interventions
- HTX-034 low dose, HTX-034 high dose, Luer lock applicator, Bupivacaine HCl
- Drug · Device
- Lead sponsor
- Heron Therapeutics
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 78 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 4
- States / cities
- Phoenix, Arizona • Bellaire, Texas • San Antonio, Texas + 1 more
- Conditions
- Acute Pain
- Interventions
- XG005 tablet, Placebo tablet
- Drug
- Lead sponsor
- Xgene Pharmaceutical Group
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 450 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 8
- States / cities
- Phoenix, Arizona • San Diego, California • Hialeah, Florida + 5 more
- Conditions
- Acute Pain
- Interventions
- Oliceridine, Placebo, Morphine
- Drug
- Lead sponsor
- Trevena Inc.
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 418 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2017
- U.S. locations
- 7
- States / cities
- Phoenix, Arizona • Anaheim, California • Pasadena, California + 4 more
- Conditions
- Medial or Lateral Instability Repairs/Reconstructions, Hallux Valgus Repairs, Achilles Tendon Repairs/Reconstructions, Midfoot Reconstructions, Metatarsal Ligament/Tendon Repairs/Reconstructions, Bunionectomy, Scapholunate Ligament Reconstructions, Ulnar, Lateral Epicondylitis Repair, Bicep Tendon Reattachments
- Interventions
- Spyromite, Dynomite, Raptomite, Footprint Ultra PK SL
- Device
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 140 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019
- U.S. locations
- 3
- States / cities
- Charlotte, North Carolina • Chardon, Ohio • Grapevine, Texas
- Conditions
- Bunion, Post-operative Pain
- Interventions
- Local anesthetic injection of CPL-01, Naropin, 0.5% Injectable Solution, Placebo, Morphine rescue medication, Acetaminophen rescue medication, Oxycodone rescue medication, Bunionectomy
- Drug · Procedure
- Lead sponsor
- Cali Pharmaceuticals LLC
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 616 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- Acute Pain
- Interventions
- SUZ, HB/APAP, Placebo (matched to SUZ), Placebo (matched to HB/APAP)
- Drug
- Lead sponsor
- Vertex Pharmaceuticals Incorporated
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 1,075 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 21
- States / cities
- Sheffield, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 18 more
- Conditions
- Acute Pain
- Interventions
- VX-150, Placebo
- Drug
- Lead sponsor
- Vertex Pharmaceuticals Incorporated
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 250 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 6
- States / cities
- Phoenix, Arizona • Anaheim, California • Pasadena, California + 3 more
- Conditions
- Hallux Valgus
- Interventions
- TLC590, Naropin®, Normal Saline, Bupivacaine
- Drug
- Lead sponsor
- Taiwan Liposome Company
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2020
- U.S. locations
- 5
- States / cities
- Phoenix, Arizona • Anaheim, California • Pasadena, Maryland + 2 more
- Conditions
- Arthralgia, Bunion, Hallux Valgus, Pain
- Interventions
- Tapentadol (CG5503), oxycodone, placebo
- Drug
- Lead sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 901 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008
- U.S. locations
- 7
- States / cities
- Glendale, California • Pasadena, Maryland • Austin, Texas + 4 more
- Conditions
- Pain Management
- Interventions
- Tramadol, Placebo
- Drug · Other
- Lead sponsor
- Avenue Therapeutics, Inc.
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 409 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 5
- States / cities
- Bakersfield, California • Pasadena, California • Pasadena, Maryland + 2 more
- Conditions
- Pain
- Interventions
- TV-46763, Placebo
- Drug
- Lead sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 569 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 8
- States / cities
- Phoenix, Arizona • Anaheim, California • Bakersfield, California + 5 more
- Conditions
- Pain, Post-operative
- Interventions
- Intranasal Dexmedetomidine, Intranasal Placebo
- Drug
- Lead sponsor
- Baudax Bio
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 168 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 3
- States / cities
- Bakersfield, California • Pasadena, California • San Antonio, Texas
- Conditions
- Pain
- Interventions
- Hydrocodone/Acetaminophen Extended Release, Acetaminophen, Morphine Extended Release, Placebo
- Drug
- Lead sponsor
- AbbVie (prior sponsor, Abbott)
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 250 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2010
- U.S. locations
- 4
- States / cities
- Peoria, Arizona • Austin, Texas • San Marcos, Texas + 1 more
- Conditions
- Post-surgical Pain
- Interventions
- CA-008, Placebo, Ketorolac, Acetaminophen, Oxycodone, Bupivacaine Hydrochloride
- Drug
- Lead sponsor
- Concentric Analgesics
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 147 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018
- U.S. locations
- 3
- States / cities
- Pasadena, California • Pasadena, Maryland • Houston, Texas