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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Burn Pain Clear all
Completed Phase 2 Interventional

Extension Study of ACTIQ Treatment for Children and Adolescents With Breakthrough Pain

NCT00236093
View directory record Official record
Conditions
Pain, Cancer, Sickle Cell Anemia, Severe Burns
Interventions
ACTIQ (Oral Transmucosal Fentanyl Citrate [OTFC])
Drug
Lead sponsor
Cephalon
Industry
Eligibility
3 Years to 15 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2006
U.S. locations
26
States / cities
Little Rock, Arkansas • Orange, California • Palo Alto, California + 21 more
Source: ClinicalTrials.gov public record
Updated May 8, 2014 · Synced Jul 22, 2026, 5:20 PM EDT
Completed Phase 2 Interventional

Immune Mechanisms of Vitamin D to Reduce Chronic Pain After Burn

NCT05619289
View directory record Official record
Conditions
Burn Injury, Chronic Pain
Interventions
Ergocalciferol, Placebo
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Jul 22, 2026, 5:20 PM EDT
Withdrawn Phase 2 Interventional

Pilot Study to Compare Topical Voriconazole to Placebo as a Pain Reducing Agent

NCT02689713
View directory record Official record
Conditions
Pain, Thermal Injury, Burns, Hyperalgesia
Interventions
Voriconazole (topical), Topical Sterile Water Placebo Group
Drug
Lead sponsor
Kenneth Hargreaves
Other
Eligibility
18 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Dec 16, 2018 · Synced Jul 22, 2026, 5:20 PM EDT
Terminated Phase 1Phase 2 Interventional

ST266 Versus Standard Care In Treating Partial Thickness Burns

NCT00886470
View directory record Official record
Conditions
Burns
Interventions
ST266
Biological
Lead sponsor
Noveome Biotherapeutics, formerly Stemnion
Industry
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
14
States / cities
Mobile, Alabama • Los Angeles, California • Gainesville, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated May 14, 2019 · Synced Jul 22, 2026, 5:20 PM EDT
Terminated Not applicable Interventional Results available

Feasibility Study of New Method of Diagnostic and Prediction of Painful CIPN

NCT03206216
View directory record Official record
Conditions
Burning Pain, Impaired Balance, Malignant Ovarian Neoplasm, Numbness, Peripheral Neuropathy, Pain, Acute, Tingling
Interventions
Diode Laser fiber type Selective Stimulator (DLss)
Diagnostic Test
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Dec 18, 2018 · Synced Jul 22, 2026, 5:20 PM EDT
Completed Not applicable Interventional

Effects of Venlafaxine on Chronic Neuropathic Pain Following Spinal Cord Injury

NCT00167856
View directory record Official record
Conditions
Neuropathic Pain, Pain, Spinal Cord Injuries
Interventions
Venalafaxine hydrochloride
Drug
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 70 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 26, 2014 · Synced Jul 22, 2026, 5:20 PM EDT
Completed Phase 3 Interventional Results available

Phase 3 Gene Therapy for Painful Diabetic Neuropathy

NCT02427464
View directory record Official record
Conditions
Painful Diabetic Neuropathy, Diabetic Neuropathy, Painful
Interventions
Engensis (VM202), placebo
Biological · Other
Lead sponsor
Helixmith Co., Ltd.
Industry
Eligibility
18 Years to 75 Years
Enrollment
507 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
25
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Los Gatos, California + 22 more
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Jul 22, 2026, 5:20 PM EDT
Completed Not applicable Interventional

VRH Pain Reduction During Burn Wound Care and Physical Therapy

NCT00260221
View directory record Official record
Conditions
Burn
Interventions
using VR hypnosis/distraction and audio hypnosis
Behavioral
Lead sponsor
National Institute of General Medical Sciences (NIGMS)
NIH
Eligibility
7 Years to 85 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2011
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 7, 2013 · Synced Jul 22, 2026, 5:20 PM EDT
Not yet recruiting Not applicable Interventional

VR-PAT and fNIRS to Identify CNS Biomarkers of Pain

NCT06303687
View directory record Official record
Conditions
Acute Pain, Pediatric ALL, Procedural Pain, Burns
Interventions
VR-PAT
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
6 Years to 17 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 23, 2025 · Synced Jul 22, 2026, 5:20 PM EDT
Completed Not applicable Interventional

Virtual Reality Analgesia for Pediatric Burn Survivors

NCT03491657
View directory record Official record
Conditions
Pain, Acute
Interventions
virtual reality distraction (Yes VR), music distraction (No VR)
Behavioral
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
6 Years to 17 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 10, 2018 · Synced Jul 22, 2026, 5:20 PM EDT
Recruiting Phase 4 Interventional

Low-Dose Ketamine Infusion During Burn Wound Care

NCT06506565
View directory record Official record
Conditions
Burn, Pain, Dissociation, Opioid
Interventions
Ketamine, 0.9% NaCl
Drug
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 12, 2024 · Synced Jul 22, 2026, 5:20 PM EDT
Active, not recruiting Not applicable Interventional

Conditioning & Open-Label Placebo (COLP) for Opioid Management in Intensive Inpatient Rehabilitation

NCT05351333
View directory record Official record
Conditions
Spinal Cord Injuries, Polytrauma, Burns
Interventions
placebo
Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 26, 2025 · Synced Jul 22, 2026, 5:20 PM EDT
Completed Phase 2 Interventional Results available

Burn Healing and Analgesia With Propranolol

NCT00934947
View directory record Official record
Conditions
Burns, Pain
Interventions
Propranolol, Placebo, Propanolol
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 59 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
4
States / cities
Washington D.C., District of Columbia • Chapel Hill, North Carolina • Wake Forest, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 16, 2017 · Synced Jul 22, 2026, 5:20 PM EDT
Not yet recruiting Not applicable Interventional

Banana Leaves as a Wound Dressing for Partial Thickness Second Degree Burns in Adult Patients.

NCT07453732
View directory record Official record
Conditions
Partial-thickness Burn, Pain, Second Degree Burn
Interventions
Banana leaf dressing
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Jul 22, 2026, 5:20 PM EDT
Completed Phase 3 Interventional Results available

Extension of Phase 3 Gene Therapy for Painful Diabetic Neuropathy

NCT04055090
View directory record Official record
Conditions
Painful Diabetic Neuropathy, Diabetic Neuropathy, Painful
Interventions
Long-Term Follow-Up of Patients who Received Engensis (VM202), Long-Term Follow-Up of Patients who Received Placebo
Genetic · Drug
Lead sponsor
Helixmith Co., Ltd.
Industry
Eligibility
18 Years to 75 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
14
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Sacramento, California + 11 more
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Jul 22, 2026, 5:20 PM EDT
Completed Phase 2Phase 3 Interventional

VR for Burn Dressing Changes at Home

NCT04548635
View directory record Official record
Conditions
Burns, Acute Pain, Procedural Pain
Interventions
VR-PAT
Device
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
5 Years to 17 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 29, 2024 · Synced Jul 22, 2026, 5:20 PM EDT
Recruiting Not applicable Interventional

VR-PMR for Post-Burn Symptoms

NCT07317271
View directory record Official record
Conditions
Burn, Chronic Pain Following Thermal Burn Injury, Non-Pharmacological Interventions, Virtual Reality, Sleep Disturbance, Anxiety, Depressive Symptoms, Fatigue Symptom, Pruritus, Burn Injury, Progressive Muscle Relaxation
Interventions
Virtual Reality-Enhanced Progressive Muscle Relaxation, Standard Progressive Muscle Relaxation
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Jul 22, 2026, 5:20 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

A Trial Comparing a Cellulose Dressing to Two Standard of Care Dressings in Treating Split Thickness Donor Sites in Burn and Wound Patients.

NCT05499104
View directory record Official record
Conditions
Donor Sites, Wound Heal, Wound Drainage, Pain Management
Interventions
NovaDress, Mepilex Ag, Xeroform
Device
Lead sponsor
Joseph M. Still Research Foundation, Inc.
Other
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 11, 2022 · Synced Jul 22, 2026, 5:20 PM EDT
Completed Not applicable Interventional

Take Charge of Burn Pain

NCT02661724
View directory record Official record
Conditions
Burn Related Pain
Interventions
TCBR-Pain
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 70 Years
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 30, 2019 · Synced Jul 22, 2026, 5:20 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

A Postmarket Randomized Study of the Treatment of Superficial Partial-Thickness Burns Using Two Dressings

NCT01067729
View directory record Official record
Conditions
Burns
Interventions
AWBAT Wound Dressing, AWBAT™, Biobrane®
Device
Lead sponsor
Aubrey Inc.
Industry
Eligibility
1 Year to 70 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2009
U.S. locations
3
States / cities
Irvine, California • Columbia, Missouri • Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 25, 2015 · Synced Jul 22, 2026, 5:20 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Reduction in Pain Intensity Following IV or Oral Pain-relieving Products

NCT02678416
View directory record Official record
Conditions
Pain
Interventions
IV Acetaminophen (Treatment A), Oral Acetaminophen (Treatment B), Placebo (Treatment C), Morphine (Treatment D)
Drug · Other
Lead sponsor
Mallinckrodt
Industry
Eligibility
18 Years to 55 Years · Male only
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 4, 2020 · Synced Jul 22, 2026, 5:20 PM EDT
Completed Phase 4 Interventional Results available

Liposomal Bupivacaine Versus Lidocaine for Skin Graft Donor Site Pain

NCT03854344
View directory record Official record
Conditions
Pain, Postoperative, Burns
Interventions
Lidocaine Hydrochloride, Liposomal bupivacaine, Bupivacaine Hydrochloride
Drug
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Jul 22, 2026, 5:20 PM EDT
Completed Phase 3 Interventional Results available

Open Multi-centre Investigation to Evaluate Signs and Symptoms of Local Inflammation/Infection on Chronic Ulcers and Partial Thickness Burns When Using Mepilex Border Ag as an Anti-microbial Wound Dressing

NCT01214811
View directory record Official record
Conditions
Inflammation, Burns, Ulcers
Interventions
Mepilex Border Ag
Device
Lead sponsor
Molnlycke Health Care AB
Industry
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
3
States / cities
Momtgomery, Alabama • Iowa City, Iowa • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Mar 7, 2013 · Synced Jul 22, 2026, 5:20 PM EDT
Completed Phase 2Phase 3 Interventional

Virtual Reality Pain Control During Burn Wound Care

NCT00261690
View directory record Official record
Conditions
Burn
Interventions
Virtual Reality Distraction
Behavioral
Lead sponsor
National Institute of General Medical Sciences (NIGMS)
NIH
Eligibility
6 Years to 60 Years
Enrollment
184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2012
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 18, 2013 · Synced Jul 22, 2026, 5:20 PM EDT