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ClinicalTrials.gov public records Last synced Oct 5, 2026, 2:30 PM EDT

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Showing 49–72 of 204 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Bypass, Gastric Clear all
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

SH Dr. Chen Gastric Bypass Study

NCT05357443
View directory record Official record
Conditions
Gastric Bypass
Interventions
Gastric bypass with transection of vagal nerves, Gastric bypass without transection of vagal nerves
Procedure
Lead sponsor
Sanford Health
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Fargo, North Dakota
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Oct 5, 2026, 2:30 PM EDT
Active, not recruiting No phase listed Observational

Transoral Fundoplication Prior to Sleeve Gastrectomy Versus RNY Gastric Bypass on GERD Symptoms in Bariatric Patients

NCT05365087
View directory record Official record
Conditions
Gastroesophageal Reflux Disease
Interventions
Transoral Fundoplication and Sleeve Gastrectomy, Gastric Bypass
Procedure
Lead sponsor
Lexington Health Incorporated
Other
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2032
U.S. locations
1
States / cities
West Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated May 8, 2025 · Synced Oct 5, 2026, 2:30 PM EDT
Completed Phase 1Phase 2 Interventional

Does Weight Loss Surgery and Probiotic Supplementation Lead to a "Lean" Gut Microbiota?

NCT01870544
View directory record Official record
Conditions
Obesity
Interventions
Lactobacillus Rhamnosus GG, Placebo
Dietary Supplement
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 10, 2016 · Synced Oct 5, 2026, 2:30 PM EDT
Withdrawn Not applicable Interventional

Evaluation of Safety and Efficacy of the EndoLift Liver Retractor

NCT02008409
View directory record Official record
Conditions
Minimally Invasive Surgical Procedure, Laparoscopic Gastric Banding, Laparoscopic Roux-en-Y Gastric Bypass, Laparoscopic Sleeve Gastrectomy, Laparoscopic Fundoplication Procedure, Laparoscopic Heller Myotomy, Laparoscopic Paraesophageal Hernia Repair, Laparoscopic Gastric Resection
Interventions
EndoLift Liver Retractor
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 5, 2015 · Synced Oct 5, 2026, 2:30 PM EDT
Completed Not applicable Interventional Results available

Surgery or Lifestyle With Intensive Medical Management in the Treatment of Type 2 Diabetes

NCT01073020
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Obesity
Interventions
Allergan Adjustable Gastric Band Surgery, Intensive Medical Diabetes & Weight Management (Why WAIT) - Band Group, Roux-en-Y Gastric Bypass (RYGB) Surgery, Intensive Medical Diabetes & Weight Management (Why WAIT) - Bypass Group
Device · Other · Procedure
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
21 Years to 65 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 28, 2021 · Synced Oct 5, 2026, 2:30 PM EDT
Not listed Not applicable Interventional

Roux-en-Y-Gastric Bypass vs. Lifestyle Modification and Medical Therapy in the Treatment of Type 2 Diabetes

NCT01231308
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Roux-en-Y-Gastric Bypass, Intensive lifestyle modification and Optimal medical Therapy
Procedure · Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
21 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 24, 2012 · Synced Oct 5, 2026, 2:30 PM EDT
Completed Phase 4 Interventional Results available

Pramlintide (Symlin) for the Treatment of Hypoglycemia Following Gastric Bypass Surgery

NCT01841359
View directory record Official record
Conditions
Hypoglycemia, Evidence of Previous Gastric Surgery
Interventions
Pramlintide
Drug
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
21 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 29, 2023 · Synced Oct 5, 2026, 2:30 PM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Endostapler Gastric Bypass Study

NCT04712526
View directory record Official record
Conditions
Obesity
Interventions
AEON Endostapler
Device
Lead sponsor
Lexington Medical Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Holyoke, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 4, 2023 · Synced Oct 5, 2026, 2:30 PM EDT
Active, not recruiting No phase listed Observational

Biological Sample Repository for Gastrointestinal Disorders

NCT05874726
View directory record Official record
Conditions
Obesity, Obesity, Morbid, Obesity, Primary, Gastro-Intestinal Disorder, Overweight and Obesity, Overweight, Overweight or Obesity, Diabetes Type 2, Diabetes Mellitus, Diabetes Mellitus, Type 2, Hypertension, Hyperlipidemias, Sleep Apnea, GERD, Gastroesophageal Reflux, Musculoskeletal Pain Disorder, Cancer
Interventions
Blood Collection, Urine Collection, Tissue Sample Collection
Diagnostic Test
Lead sponsor
Pichamol Jirapinyo, MD, MPH
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Oct 5, 2026, 2:30 PM EDT
Completed Not applicable Interventional

Mechanisms of Diabetes Relapse After Bariatric Surgery

NCT01516320
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Roux-en-Y Gastric Bypass, Laparoscopic adjustable gastric banding, Vertical Sleeve Gastrectomy
Procedure
Lead sponsor
Blandine Laferrere
Other
Eligibility
18 Years to 65 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 1, 2017 · Synced Oct 5, 2026, 2:30 PM EDT
Completed Not applicable Interventional

Enhanced Recovery After Surgery in Laparoscopic Sleeve Gastrectomy

NCT03520803
View directory record Official record
Conditions
Obesity
Interventions
Enhanced recovery after surgery protocol
Other
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 9, 2021 · Synced Oct 5, 2026, 2:30 PM EDT
Not listed Not applicable Interventional

Laparoscopic Gastric Bypass for Type 2 Diabetes Mellitus With Body Mass Index (BMI) < 35

NCT00999050
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Gastric bypass for diabetic patients <35 BMI
Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 4, 2011 · Synced Oct 5, 2026, 2:30 PM EDT
Terminated Phase 1Phase 2 Interventional Accepts healthy volunteers

Safety, Tolerability, and Pharmacodynamics of NOV-001 in Adult Subjects

NCT04909723
View directory record Official record
Conditions
Healthy Volunteers, Enteric Hyperoxaluria
Interventions
NOV-001, NB1000S, NB2000P, Placebo
Combination Product · Biological · Drug
Lead sponsor
Novome Biotechnologies Inc
Industry
Eligibility
18 Years to 65 Years
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
19
States / cities
Birmingham, Alabama • Scottsdale, Arizona • Daytona Beach, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated May 17, 2023 · Synced Oct 5, 2026, 2:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Tri Staple Technology Stapler Used in Gastric Bypass

NCT01026103
View directory record Official record
Conditions
Sleep Apnea, Hypertension, Hyperlipidemia, Coronary Artery Disease, Gastroesophageal Reflux Disease, Osteoarthritis, Diabetes
Interventions
Tri Staple Technology stapler
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 14, 2014 · Synced Oct 5, 2026, 2:30 PM EDT
Active, not recruiting No phase listed Observational

Comparison Between Gastric Band, Laparoscopic Sleeve Gastrectomy, Gastric Bypass Surgeries

NCT02004561
View directory record Official record
Conditions
Obese Adolescents
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
14 Years to 19 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Oct 5, 2026, 2:30 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Ghrelin and Insulin Resistance

NCT00884494
View directory record Official record
Conditions
Obesity, Insulin Resistance, Normal Weight,Healthy Controls
Interventions
Ghrelin infusion to assess effects on insulin sensitivity
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 20, 2017 · Synced Oct 5, 2026, 2:30 PM EDT
Completed Not applicable Interventional

Effect of Meal Number, Frequency, and Form on Satiety and Metabolism After Weight Loss Surgery

NCT01938469
View directory record Official record
Conditions
Gastric Bypass Surgery, Obesity
Interventions
Liquid Meal, Solid Meal
Other
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
21 Years to 60 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 29, 2016 · Synced Oct 5, 2026, 2:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nutritional Effect of an Amino Acid Mixture on Lean Body Mass (LBM) in Post-bariatric Surgery Patients

NCT00473356
View directory record Official record
Conditions
Obesity, Post-gastric Bypass
Interventions
receive amino acid supplement
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 19, 2013 · Synced Oct 5, 2026, 2:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Use of Radiofrequency Ablation for RGB Salvage

NCT01910688
View directory record Official record
Conditions
Obesity
Interventions
RFA treatment
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
2
States / cities
Lebanon, New Hampshire • New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 24, 2016 · Synced Oct 5, 2026, 2:30 PM EDT
Completed Not applicable Interventional

DSS: Diabetes Surgery Study - Intensive Medical Management of Type 2 Diabetes, With and Without Gastric Bypass Surgery

NCT00641251
View directory record Official record
Conditions
Type 2 Diabetes, Cardiovascular Disease
Interventions
intensive medical management, RYGB & IMM
Other
Lead sponsor
Medtronic - MITG
Industry
Eligibility
30 Years to 67 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
3
States / cities
Minneapolis, Minnesota • Rochester, Minnesota • New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 29, 2017 · Synced Oct 5, 2026, 2:30 PM EDT
Completed Not applicable Interventional

Metabolic Surgery Versus Medical Management for Resolution of Type II Diabetes

NCT01044602
View directory record Official record
Conditions
Obesity, Type 2 Diabetes Mellitus
Interventions
Laboratory evaluations, sleep study, Best Medical Management, Roux-en-Y gastric bypass surgery
Other · Procedure
Lead sponsor
David Bradley MD
Other
Eligibility
25 Years to 70 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 21, 2015 · Synced Oct 5, 2026, 2:30 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effects of Bariatric Surgery on Insulin

NCT00535600
View directory record Official record
Conditions
Obesity, Bariatric Surgery, Gastric Bypass, Weight Loss, Hyperglycemia
Interventions
Not listed
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 96 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2014
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Oct 5, 2026, 2:30 PM EDT
Terminated No phase listed Observational Results available

Metabolic Factors of Outcomes From Gastric Bypass Surgery

NCT01347840
View directory record Official record
Conditions
Obesity
Interventions
Not listed
Lead sponsor
Ethicon Endo-Surgery
Industry
Eligibility
18 Years to 65 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated May 21, 2012 · Synced Oct 5, 2026, 2:30 PM EDT
Completed Not applicable Interventional Results available

Evaluation of Endostapled Anastomoses for Laparoscopic Gastric Bypass (EEA-LGB)

NCT00254072
View directory record Official record
Conditions
Morbid Obesity
Interventions
3.5 mm vs 4.8 mm Stapler During Laparoscopic Gastric Bypass
Procedure
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 60 Years
Enrollment
355 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
6
States / cities
Orange, California • Tampa, Florida • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 18, 2010 · Synced Oct 5, 2026, 2:30 PM EDT