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ClinicalTrials.gov public records Last synced Oct 16, 2026, 8:38 AM EDT

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Showing 841–864 of 1,399 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: CAD - Coronary Artery Disease Clear all
Completed Phase 2 Interventional Results available

Effects of Magnesium on Individuals Undergoing Coronary Artery Bypass Graft Surgery

NCT00041392
View directory record Official record
Conditions
Coronary Disease, Heart Diseases, Cardiovascular Diseases, Neurologic Manifestations
Interventions
Magnesium, 0.9% saline
Drug
Lead sponsor
Duke University
Other
Eligibility
55 Years and older
Enrollment
389 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2009
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 30, 2013 · Synced Oct 16, 2026, 8:38 AM EDT
Terminated No phase listed Observational

Assessing Diagnostic Value of Non-invasive FFR-CT in Coronary Care in the Emergency Department

NCT05325112
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
FFR-CT
Diagnostic Test
Lead sponsor
HeartFlow, Inc.
Industry
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
2
States / cities
Worcester, Massachusetts • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 16, 2026, 8:38 AM EDT
Terminated Not applicable Interventional Results available

Simultaneous Assessment of FFR and SPECT

NCT02749045
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
SPECT imaging
Radiation
Lead sponsor
Prem Soman
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 2, 2022 · Synced Oct 16, 2026, 8:38 AM EDT
Recruiting No phase listed Observational

OPN Balloon for SAFE Recanalization of Calcified Coronary Lesions

NCT07646444
View directory record Official record
Conditions
Coronary Arterial Disease (CAD), In Stent Restenosis, Calcified Coronary Lesions
Interventions
non compliant balloon
Device
Lead sponsor
Minneapolis Heart Institute Foundation
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 16, 2026, 8:38 AM EDT
Completed Not applicable Interventional Results available

Piloting the IPROACTIF Program to Preserve Functioning and Prevent Cognitive Decline

NCT04682977
View directory record Official record
Conditions
Heart Disease (Coronary Artery Disease, Ischemic Heart Disease, Hypertensive Heart Disease), Uncontrolled Diabetes (HBA1c ≥ 10)
Interventions
IPROACTIF (Integrated PRimary Care and Occupational Therapy for Aging and Chronic Disease Treatment to preserve Independence and Functioning), Usual primary care services
Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
55 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 19, 2025 · Synced Oct 16, 2026, 8:38 AM EDT
Completed Phase 1 Interventional

Assessment of Coronary Plaque Composition

NCT01581632
View directory record Official record
Conditions
Coronary Atherosclerosis, Endothelial Dysfunction, Coronary Small Vessel Disease
Interventions
LipiScan/LipiScan IVUS
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 5, 2019 · Synced Oct 16, 2026, 8:38 AM EDT
Completed Not applicable Interventional

Early Identification of Subclinical Atherosclerosis Using Non-Invasive Imaging Research (EISNER)

NCT00927693
View directory record Official record
Conditions
Atherosclerosis, Coronary Artery Disease
Interventions
Coronary Artery Calcium (CAC) Scan
Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
45 Years to 80 Years
Enrollment
2,137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2010
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 29, 2011 · Synced Oct 16, 2026, 8:38 AM EDT
Terminated Not applicable Interventional

Safety and Efficacy Study of the SoundBite™ Crossing System With ACTIVE Wire in Coronary CTOs.

NCT03521804
View directory record Official record
Conditions
Chronic Total Occlusion of Coronary Artery
Interventions
SoundBite™ Crossing System Active Wire 14
Device
Lead sponsor
SoundBite Medical Solutions, Inc.
Industry
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 6, 2023 · Synced Oct 16, 2026, 8:38 AM EDT
Not listed No phase listed Observational

Assessment of Catheter-based Interrogation and Standard Techniques for Fractional Flow Reserve Measurement

NCT02577484
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
RXi System, Pressure Wire
Device
Lead sponsor
Acist Medical Systems
Industry
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
12
States / cities
La Jolla, California • Long Beach, California • Stanford, California + 8 more
Source: ClinicalTrials.gov public record
Updated Dec 6, 2016 · Synced Oct 16, 2026, 8:38 AM EDT
Completed No phase listed Observational Results available

Multi-center Prospective Study to Evaluate Outcomes of the Moderate to Severely Calcified Coronary Lesions (MACE)

NCT01930214
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Percutaneous Coronary Intervention
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
34
States / cities
Little Rock, Arkansas • Glendale, California • Hartford, Connecticut + 30 more
Source: ClinicalTrials.gov public record
Updated Jul 18, 2023 · Synced Oct 16, 2026, 8:38 AM EDT
Completed No phase listed Observational

Pilot Study on the Effect of High Clopidogrel Maintenance Dosing

NCT01118793
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Clopidogrel
Drug
Lead sponsor
Scripps Health
Other
Eligibility
18 Years to 85 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 23, 2022 · Synced Oct 16, 2026, 8:38 AM EDT
Active, not recruiting Not applicable Interventional

The Minimally Invasive Coronary Surgery Compared to STernotomy Coronary Artery Bypass Grafting Trial

NCT03447938
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
MICS CABG, Conventional CABG
Procedure
Lead sponsor
Ottawa Heart Institute Research Corporation
Other
Eligibility
18 Years and older
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2028
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • La Crosse, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Oct 16, 2026, 8:38 AM EDT
Completed Phase 2 Interventional Results available

Polypill in Acute Coronary Syndrome

NCT05514938
View directory record Official record
Conditions
Acute Coronary Syndrome, Lipid Disorder, Coronary Artery Disease
Interventions
Polypill, Usual Care (individual medications prescribed by primary cardiologist)
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 16, 2026, 8:38 AM EDT
Completed Not applicable Interventional Results available

Dynamic Coronary Roadmap for Contrast Reduction

NCT04085614
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Percutaneous Coronary Intervention (PCI) with Dynamic Coronary Roadmap, Percutaneous Coronary Intervention (PCI) without Dynamic Coronary Roadmap
Device
Lead sponsor
Philips Clinical & Medical Affairs Global
Industry
Eligibility
18 Years and older
Enrollment
371 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
Denver, Colorado • New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 8, 2024 · Synced Oct 16, 2026, 8:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Plasma TMAO and Choline Levels in Individuals With Metabolic Syndrome - Comparison Between Eggs and Choline Supplement.

NCT03877003
View directory record Official record
Conditions
Coronary Artery Disease, Diabetes, Metabolic Syndrome
Interventions
Eggs
Other
Lead sponsor
University of Connecticut
Other
Eligibility
35 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
2
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 3, 2020 · Synced Oct 16, 2026, 8:38 AM EDT
Completed Not applicable Interventional Results available

Clinical Investigation for Safety and Efficacy Study of CELT ACD (Arterial ClosureDevice)

NCT01600482
View directory record Official record
Conditions
Cardiac Disease, Coronary Artery Disease
Interventions
CELT ACD
Device
Lead sponsor
Vasorum Ltd
Industry
Eligibility
18 Years and older
Enrollment
241 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
2
States / cities
Camden, New Jersey • New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 23, 2017 · Synced Oct 16, 2026, 8:38 AM EDT
Recruiting No phase listed Observational

A Precision Medicine Approach to Identify Patients Undergoing Elective PCI at Risk of Peri-PCI Myocardial Infarction

NCT05332262
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Assessment of platelet reactivity, Troponin measurement
Diagnostic Test
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 16, 2026, 8:38 AM EDT
Completed Phase 4 Interventional Results available

Switching From DAPT to Dual Pathway Inhibition With Low-dose Rivaroxaban in Adjunct to Aspirin in Patients With Coronary Artery Disease

NCT04006288
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Clopidogrel, Prasugrel, ticagrelor, aspirin, rivaroxaban
Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 26, 2023 · Synced Oct 16, 2026, 8:38 AM EDT
Completed Not applicable Interventional Results available

Absorb IV Randomized Controlled Trial

NCT02173379
View directory record Official record
Conditions
Coronary Artery Disease, Coronary Artery Stenosis, Coronary Disease, Coronary Stenosis
Interventions
Absorb BVS, XIENCE
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
2,604 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
98
States / cities
Birmingham, Alabama • Chandler, Arizona • Gilbert, Arizona + 82 more
Source: ClinicalTrials.gov public record
Updated Oct 30, 2023 · Synced Oct 16, 2026, 8:38 AM EDT
Terminated Phase 1Phase 2 Interventional

Red Blood Cell Transfusion in Patients With Coronary Artery Disease (CAD)

NCT01504945
View directory record Official record
Conditions
Acute Coronary Syndrome, Anemia
Interventions
RBC transfusion, Normal saline infusion
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 100 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 23, 2018 · Synced Oct 16, 2026, 8:38 AM EDT
Completed No phase listed Observational Results available

Disrupt CAD III Post-Approval Study (PAS)

NCT05021757
View directory record Official record
Conditions
Coronary Artery Disease, Myocardial Infarction
Interventions
Shockwave C2 Coronary IVL
Device
Lead sponsor
Shockwave Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1,212 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Feb 1, 2024 · Synced Oct 16, 2026, 8:38 AM EDT
Not yet recruiting Not applicable Interventional

Inorganic Nitrate as a Treatment for ANOCA: NO-ANOCA

NCT06948201
View directory record Official record
Conditions
Coronary Microvascular Dysfunction (CMD), Angina Patients With Non-obstructive Coronary Artery Disease
Interventions
70mL Nitrate Rich Beetroot Juice followed by placebo (Nitrate depleted beetroot juice), Placebo (70 mL Nitrate depleted beetroot juice) followed by 70mL Nitrate Rich Beetroot Juice
Dietary Supplement
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older · Female only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 29, 2025 · Synced Oct 16, 2026, 8:38 AM EDT
Terminated Phase 4 Interventional Results available

Evaluation of a Combined Near Infrared Spectroscopy (NIRS) and Intravascular Ultrasound (IVUS) Catheter for Detection of Lipid Rich Plaque

NCT01506960
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
InfraReDx Lipiscan IVUS
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 79 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 18, 2013 · Synced Oct 16, 2026, 8:38 AM EDT
Completed Phase 4 Interventional Results available

Anti-inflammatory Effects of Colchicine in PCI

NCT01709981
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Colchicine, Placebo
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
3
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 25, 2022 · Synced Oct 16, 2026, 8:38 AM EDT