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ClinicalTrials.gov public records Last synced Nov 6, 2026, 6:30 AM EST

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Showing 1–24 of 496 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: CHF - Congestive Heart Failure Clear all

Conditions: Congenital Heart Disease
Interventions: Not listed
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: 18 Years to 80 Years
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2019
U.S. locations: 3
States / cities: Washington D.C., District of Columbia • Bethesda, Maryland

Conditions: Congestive Heart Failure, Cardiac Resynchronization Therapy
Interventions: Kronos LV-T, Lumax HF-T; Device
Lead sponsor: Biotronik, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 12
States / cities: Phoenix, Arizona • Scottsdale, Arizona • Wilmington, Delaware + 9 more

Conditions: Heart Failure, Congestive, Chronic Heart Failure, Depression
Interventions: Sertraline, Placebo; Drug
Lead sponsor: Duke University; Other
Eligibility: 45 Years and older
Enrollment: 469 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2008
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Congestive Heart Failure
Interventions: Monitoring on heart failure therapy; Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 21 Years to 100 Years
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Heart Failure, Congestive
Interventions: KW-3902IV; Drug
Lead sponsor: NovaCardia, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA); Industry
Eligibility: 18 Years and older
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2004
U.S. locations: 10
States / cities: Stanford, California • Washington D.C., District of Columbia • Sarasota, Florida + 7 more

Conditions: Diastolic Heart Failure
Interventions: Atorvastatin, placebo; Drug · Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Heart Failure
Interventions: Medtronic Pacemaker; Device
Lead sponsor: Columbia University; Other
Eligibility: 18 Years to 90 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: New York, New York

Conditions: Congestive Heart Failure, Non-ischemic Cardiomyopathy
Interventions: Triheptanoin oil; Drug
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Atrial Fibrillation, Congestive Heart Failure
Interventions: Not listed
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: 18 Years and older
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Heart Failure
Interventions: CHF Self-management Education (Web-based Education); Behavioral
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: Not listed
Enrollment: 700 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Ends 2004
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Congestive Heart Failure
Interventions: Blood Volume Analysis, Echocardiogram; Procedure
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Heart Failure, Congestive
Interventions: Not listed
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1988 – 2028
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Congestive Heart Failure, Chronic Obstructive Pulmonary Disease, Diabetes
Interventions: Home care telemedicine; Procedure
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Ends 2004
U.S. locations: 2
States / cities: Ann Arbor, Michigan • Indianapolis, Nebraska

Conditions: Congestive Heart Failure, Coronary Artery Disease, Myocardial Infarction
Interventions: MyoCell™ Autologous Myoblasts; Drug
Lead sponsor: Bioheart, Inc.; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006
U.S. locations: 5
States / cities: Fort Lauderdale, Florida • Atlanta, Georgia • Chicago, Illinois + 2 more

Conditions: Cardiac Failure, Congestive Heart Failure
Interventions: Heart Failure Disease Management Program, Heart Failure Usual Care; Other
Lead sponsor: University of Colorado, Denver; Other
Eligibility: Not listed
Enrollment: 713 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2019
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Congestive Heart Failure
Interventions: CRT Algorithm; Device
Lead sponsor: Deborah Heart and Lung Center; Other
Eligibility: 18 Years and older
Enrollment: 92 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Browns Mills, New Jersey

Conditions: Heart Decompensation
Interventions: Kaneka Liposorber; Device
Lead sponsor: Patrick Moriarty, MD, FACP, FACC; Other
Eligibility: 18 Years to 85 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Congestive Heart Failure
Interventions: Aquadex system, IV diuretic; Device · Drug
Lead sponsor: Nuwellis, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2005
U.S. locations: 1
States / cities: Lombard, Illinois

Conditions: Metastatic Cancer, Congestive Heart Failure, Chronic Obstructive Pulmonary Disease, Parkinson Disease, Interstitial Lung Disease, Amyotrophic Lateral Sclerosis, End Stage Liver Disease, End Stage Renal Disease, Diabetes Complications
Interventions: Respecting Choices First Steps, Five Wishes Form; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 65 Years and older
Enrollment: 790 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 4
States / cities: Birmingham, Alabama • Atlanta, Georgia • Columbia, South Carolina + 1 more

Conditions: Congestive Heart Failure, Atrial Arrhythmia, Atrial Tachyarrhythmia, Atrial Fibrillation
Interventions: Cardiac Resynchronization Therapy+Implantable Cardioverter Defibrillator; Device
Lead sponsor: Medtronic Cardiac Rhythm and Heart Failure; Industry
Eligibility: 18 Years and older
Enrollment: 270 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 30
States / cities: Anchorage, Alaska • Phoenix, Arizona • Santa Monica, California + 27 more

Conditions: Coronary Artery Disease, Congestive Heart Failure
Interventions: Treatment group; Biological
Lead sponsor: University of Louisville; Other
Eligibility: 18 Years to 75 Years
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Louisville, Kentucky

Conditions: Congestive Heart Failure, Systolic Dysfunction
Interventions: Not listed
Lead sponsor: Trinity Health Of New England; Other
Eligibility: 18 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Hartford, Connecticut

Conditions: Cardiovascular Diseases, Heart Diseases, Heart Failure, Congestive
Interventions: Mechanical Circulatory Support Device (MCSD); Device
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: 1 Day and older
Enrollment: 23,472 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2017
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Heart Failure Congestive
Interventions: Bumetanide, intranasal 4mg; Drug
Lead sponsor: Prisma Health-Upstate; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Greenville, South Carolina

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Myocardial Perfusion and Scarring in Congenital Heart Disease

TRIAGE-CRT Telemonitoring in Patients With CHF and Indication of CRT-D

Antidepressant Medication Treatment for Depression in Individuals With Chronic Heart Failure

Plasma ExtrAcellular RNAs and Biomarkers of Heart FaiLure During Decongestion: PEARL-HF Study

Dose Escalation Study of KW-3902 on Diuresis in Subjects With Congestive Heart Failure (CHF).

Effects of Statin Therapy on Vascular Properties and Outcomes in Diastolic Heart Failure Patients

Cardiovascular and Neurohormonal Effects of Faster Atrial Pacing Rate

Study of the Acute Effects of Triheptanoin in Heart Failure

AVJ Ablation Followed by Resynchronization Therapy in Patients With CHF and AF

Trial of a Tailored Message Program to Implement CHF Guidelines

Correlation of Intrathoracic Impedance Measures With Blood Plasma Volume in Congestive Heart Failure

Magnetic Resonance Spectroscopy Studies of Cardiac Muscle Metabolism

An Evaluation of Home-Based Telemedicine Services

Autologous Cultured Myoblasts (BioWhittaker) Transplanted Via Myocardial Injection

Heart Failure Management Program Versus Usual Care

Paced And Sensed Electrical Delay in CRT Therapy (PASED CRT)

Treating Congestive Heart Failure Using a Device to Remove Cholesterol

Ultrafiltration Versus Intravenous (IV) Diuretics for Patients Hospitalized for Acute Decompensated Heart Failure: (UNLOAD)

Reducing Disparities in the Quality of Advance Care Planning for Older Adults

Clinical Investigation of the Medtronic Concerto™ Device

Cardiac Stem Cell Infusion in Patients With Ischemic CardiOmyopathy (SCIPIO)

Effect of Post Discharge Follow-up on Readmission Rates for Congestive Heart Failure Patients

Interagency Registry for Mechanically Assisted Circulatory Support (Intermacs)

VAPorized Administration of Bumetanide for Outpatient Relief in Heart Failure