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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: CLBP - Chronic Low Back Pain Clear all
Terminated Not applicable Interventional

Feasibility of Telehealth Mindfulness for Back Pain in the Emergency Department

NCT04783532
View directory record Official record
Conditions
Low Back Pain, Back Pain, Pain, Chronic Low-back Pain
Interventions
Telehealth Mindfulness Program
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 30, 2022 · Synced Jun 26, 2026, 3:52 AM EDT
Completed Phase 4 Interventional Results available

Effectiveness of Ultrasound Guided Platelet Rich Plasma Injections in the Sacroiliac Joint

NCT03122119
View directory record Official record
Conditions
Chronic Low Back Pain, Sacroiliitis, Sacroiliac; Backache, Platelet Rich Plasma, Platelet, Injection Site, Ultrasound Therapy; Complications, Treatment
Interventions
Platelet Rich Plasma Joint Injection
Drug
Lead sponsor
Star Spine and Sport
Other
Eligibility
18 Years to 80 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Golden, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 27, 2023 · Synced Jun 26, 2026, 3:52 AM EDT
Completed Phase 3 Interventional

Open Label Safety and Tolerability Study of COV155 in Subjects With Osteoarthritis (OA) or Chronic Low Back Pain (CLBP)

NCT01722864
View directory record Official record
Conditions
Osteoarthritis, Knee, Osteoarthritis, Hip, Chronic Low Back Pain
Interventions
COV155
Drug
Lead sponsor
Mallinckrodt
Industry
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
34
States / cities
Anaheim, California • Lomita, California • Santa Ana, California + 24 more
Source: ClinicalTrials.gov public record
Updated Oct 18, 2016 · Synced Jun 26, 2026, 3:52 AM EDT
Completed Not applicable Interventional

Optimizing Chronic Pain Management Through Patient Engagement With Quality of Life Measures

NCT04168437
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Health-Related Quality of Life Report
Other
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
21 Years to 79 Years
Enrollment
331 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated May 18, 2022 · Synced Jun 26, 2026, 3:52 AM EDT
Active, not recruiting Not applicable Interventional

TeleYoga for Chronic Low Back Pain: A Quantitative and Qualitative Study

NCT07216417
View directory record Official record
Conditions
Low Back Pain
Interventions
Yoga, Mindfulness
Behavioral
Lead sponsor
Taylor Rees
Other
Eligibility
30 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Jun 26, 2026, 3:52 AM EDT
Completed Not applicable Interventional Results available

Targeted Interventions to Prevent Chronic Low Back Pain in High Risk Patients

NCT02647658
View directory record Official record
Conditions
Low Back Pain
Interventions
Guideline Based Care plus Psychologically Informed Physical Therapy, Guideline Based Care (GBC)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
2,300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
5
States / cities
Baltimore, Maryland • Boston, Massachusetts • Pittsburgh, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 9, 2020 · Synced Jun 26, 2026, 3:52 AM EDT
Active, not recruiting Not applicable Interventional Results available

EaseVRx-8w+ for the Treatment of Chronic Lower Back Pain

NCT05263037
View directory record Official record
Conditions
Chronic Low-back Pain, Anxiety, Depression
Interventions
EaseVRx, Sham VR
Device
Lead sponsor
AppliedVR Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
1,093 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Van Nuys, California
Source: ClinicalTrials.gov public record
Updated Jan 28, 2025 · Synced Jun 26, 2026, 3:52 AM EDT
Completed Not applicable Interventional Results available

Imaging Study of Chronic Low Back Pain in Patients Taking Pain Medication

NCT00388414
View directory record Official record
Conditions
Low Back Pain
Interventions
duloxetine, Placebo
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 60 Years · Male only
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 10, 2017 · Synced Jun 26, 2026, 3:52 AM EDT
Terminated Phase 4 Interventional Results available

Percutaneous Neuromodulation Therapy (PNT) With Chronic Low Back Pain Patients

NCT00290238
View directory record Official record
Conditions
Low Back Pain
Interventions
Vertis Percutaneous Neuromodulation Therapy (PNT), Transcutaneous Electrical Nerve Stimulation (TENS)
Device
Lead sponsor
RS Medical
Industry
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
8
States / cities
La Jolla, California • Atlanta, Georgia • Eugene, Oregon + 5 more
Source: ClinicalTrials.gov public record
Updated May 31, 2009 · Synced Jun 26, 2026, 3:52 AM EDT
Recruiting Phase 2 Interventional

Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression

NCT06419439
View directory record Official record
Conditions
Chronic Low Back Pain, Depression
Interventions
Ketamine hydrochloride, Minimally Enhanced Usual Care, Brief narrative intervention
Drug · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Jun 26, 2026, 3:52 AM EDT
Completed Phase 3 Interventional

Non-Invasive Targeted Electronic Pain Control Device ("Biowave System") Versus Transcutaneous Electrical Nerve Stimulation (TENS) for the Symptomatic Treatment of Chronic Low Back Pain

NCT00277797
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Biowave Targeted Non-Invasive Electronic Pain Control Device, TENS (Transcutaneous Electrical Nerve Stimulation) device
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 16, 2013 · Synced Jun 26, 2026, 3:52 AM EDT
Completed Not applicable Interventional

Virtual Reality Trial Using EaseVRx For Chronic Low Back Pain

NCT04415177
View directory record Official record
Conditions
Chronic Lower Back Pain
Interventions
EaseVRx headset with active intervention, EaseVRx headset without active intervention
Device
Lead sponsor
AppliedVR Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 10, 2022 · Synced Jun 26, 2026, 3:52 AM EDT
Completed Not applicable Interventional Results available

Trial of Scrambler Therapy or Sham Treatment for Low Back Pain

NCT01896687
View directory record Official record
Conditions
Low Back Pain
Interventions
Scrambler
Device
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 13, 2017 · Synced Jun 26, 2026, 3:52 AM EDT
Suspended Not applicable Interventional

Chromatic Retinal Stimulation to Reduce Chronic Pain and Pain Sensitivity

NCT05956067
View directory record Official record
Conditions
Chronic Low-back Pain, Chronic Pain, Fibromyalgia
Interventions
Green Light stimulation, Equal Energy White stimulation, S-cone modulating white light
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Jun 26, 2026, 3:52 AM EDT
Recruiting Not applicable Interventional

A Multicomponent Intervention for Patients With Lumbosacral Radiculopathy: Move-MORE

NCT07125027
View directory record Official record
Conditions
Lumbosacral Radiculopathy, Sciatica, Chronic Low Back Pain With a Neuropathic Component, Radiculopathy Lumbar, Chronic Pain (Back / Neck)
Interventions
Move-MORE
Behavioral
Lead sponsor
National University of Natural Medicine
Other
Eligibility
18 Years to 66 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 11, 2025 · Synced Jun 26, 2026, 3:52 AM EDT
Recruiting Not applicable Interventional

How Osteopathic Treatment Affects the Leg and Foot in People With Low Back Pain

NCT07193212
View directory record Official record
Conditions
Chronic Low Back Pain (CLBP)
Interventions
Osteopathic Manipulative Treatment
Other
Lead sponsor
Edward Via Virginia College of Osteopathic Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Jun 26, 2026, 3:52 AM EDT
Completed Phase 4 Interventional Results available

The Back Pain Consortium Research Program Study

NCT04870957
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
PainGuide, MBSR, PT and exercise, Self -administered acupressure, Duloxetine, Pro-Diary monitor
Behavioral · Device · Drug
Lead sponsor
University of Michigan
Other
Eligibility
25 Years to 70 Years
Enrollment
494 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Jun 26, 2026, 3:52 AM EDT
Completed Phase 3 Interventional Results available

Efficacy Study to Evaluate Buprenorphine HCl Buccal Film in Opioid-Experienced Subjects

NCT01675167
View directory record Official record
Conditions
Low Back Pain
Interventions
Buprenorphine, Placebo
Drug
Lead sponsor
BioDelivery Sciences International
Industry
Eligibility
18 Years and older
Enrollment
815 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
66
States / cities
Birmingham, Alabama • Haleyville, Alabama • Mobile, Alabama + 57 more
Source: ClinicalTrials.gov public record
Updated Feb 26, 2017 · Synced Jun 26, 2026, 3:52 AM EDT
Completed Not applicable Interventional

Chronic Low Back Pain Graded - Exposure Psychoeducation Intervention

NCT03909048
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Interactive - Psychoeducation, Non-interactive Psychoeducation
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 30, 2019 · Synced Jun 26, 2026, 3:52 AM EDT
Completed Not applicable Interventional

A Pilot Study Examining the Efficacy of Biomodulator Treatment for Chronic Low Back Pain

NCT02707094
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Biomodulator, Usual Care (Medication + Exercise)
Device · Other
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 62 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 4, 2018 · Synced Jun 26, 2026, 3:52 AM EDT
Completed Phase 3 Interventional Results available

Phase 3 Study of Hydrocodone Bitartrate Controlled-release Capsules in Subjects With Chronic Low Back Pain

NCT01081912
View directory record Official record
Conditions
Back Pain Lower Back Chronic
Interventions
Placebo, Hydrocodone bitartrate
Drug
Lead sponsor
Zogenix, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
510 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
51
States / cities
Phoenix, Arizona • Jonesboro, Arkansas • Anaheim, California + 47 more
Source: ClinicalTrials.gov public record
Updated Dec 7, 2022 · Synced Jun 26, 2026, 3:52 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Partial Sleep Restriction in Chronic Low Back Pain: A Feasibility Study

NCT07008924
View directory record Official record
Conditions
Chronic Low-back Pain, Insomnia, Sleep
Interventions
No intervention is provided. We monitor natural recovery to full sleep.
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
25 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jun 5, 2025 · Synced Jun 26, 2026, 3:52 AM EDT
Recruiting Not applicable Interventional

Phenotyping Response to Spinal Cord Stimulation in Chronic Low Back Pain

NCT06310226
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Epidural electrical spinal cord stimulator
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Jun 26, 2026, 3:52 AM EDT
Terminated Phase 2 Interventional

A Dose-ranging Study of the Safety and Effectiveness of JNJ-42160443 as add-on Treatment in Patients With Low Back Pain

NCT00973024
View directory record Official record
Conditions
Low Back Pain, Low Back Pain, Recurrent
Interventions
JNJ-42160443 3 mg, JNJ-42160443 1 mg, JNJ-42160443 6 mg/3mg, JNJ-42160443 10 mg, Matching Placebo
Drug
Lead sponsor
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Industry
Eligibility
18 Years to 80 Years
Enrollment
389 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
41
States / cities
Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 38 more
Source: ClinicalTrials.gov public record
Updated Jun 5, 2016 · Synced Jun 26, 2026, 3:52 AM EDT