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Showing 1–19 of 19 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: CMC Arthritis Clear all
Recruiting No phase listed Observational

Study on Basal Joint Arthritis Prospective

NCT01376024
View directory record Official record
Conditions
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2027
U.S. locations
3
States / cities
Rochester, Minnesota • New York, New York • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Jul 22, 2026, 10:21 PM EDT
Completed Phase 2Phase 3 Interventional

Double-Blind,Randomized,Placebo-Controlled Efficacy & Safety Study of EUFLEXXA™ for Treatment of OA of the First CMC

NCT00423371
View directory record Official record
Conditions
Osteoarthritis
Interventions
sodium hyaluronate, placebo
Device
Lead sponsor
Ferring Pharmaceuticals
Industry
Eligibility
40 Years and older
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
St. Petersburg, Florida
Source: ClinicalTrials.gov public record
Updated May 18, 2011 · Synced Jul 22, 2026, 10:21 PM EDT
Recruiting Phase 3 Interventional

NSAID Injection Versus Corticosteroid Injection for Basilar Thumb Arthritis

NCT05992883
View directory record Official record
Conditions
Thumb Osteoarthritis
Interventions
Ketorolac, Triamcinolone
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 22, 2026 · Synced Jul 22, 2026, 10:21 PM EDT
Not listed Not applicable Interventional

Safety and Effectiveness of Cartiva Implant in the Treatment of First CMC Joint Osteoarthritis Compared to LRTI (GRIP 2)

NCT03247439
View directory record Official record
Conditions
Osteoarthritis
Interventions
Cartiva
Device
Lead sponsor
Cartiva, Inc.
Industry
Eligibility
22 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
5
States / cities
San Diego, California • Atlanta, Georgia • Indianapolis, Indiana + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 2, 2020 · Synced Jul 22, 2026, 10:21 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Prevalence of the Linburg-Comstock Variation

NCT06142370
View directory record Official record
Conditions
Anomaly; Hand
Interventions
Descriptive
Other
Lead sponsor
Russell Sage College
Other
Eligibility
35 Years to 89 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Nov 20, 2023 · Synced Jul 22, 2026, 10:21 PM EDT
Completed Not applicable Interventional

Postoperative Rehabilitation Following Trapeziectomy and Ligament Reconstruction Tendon Interposition

NCT01425034
View directory record Official record
Conditions
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Interventions
casts for the thumb, Motion group
Other
Lead sponsor
University of Utah
Other
Eligibility
40 Years to 80 Years
Enrollment
234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2019
U.S. locations
1
States / cities
Murray, Utah
Source: ClinicalTrials.gov public record
Updated Aug 19, 2019 · Synced Jul 22, 2026, 10:21 PM EDT
Not listed Not applicable Interventional

Efficacy of a Single Injection of CTM for Post-Operative CMC Arthritis

NCT06171529
View directory record Official record
Conditions
Osteoarthritis, Osteoarthritis Thumb Base Joint, Carpometacarpal Osteoarthritis, Thumb
Interventions
CTM, Placebo
Device · Other
Lead sponsor
Indiana Hand to Shoulder Center
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 27, 2024 · Synced Jul 22, 2026, 10:21 PM EDT
Enrolling by invitation Phase 1 Interventional

Oral Curcumin for the Treatment of Pain of Thumb Base Joint (CMC) Arthritis

NCT06359665
View directory record Official record
Conditions
Arthritis of Carpometacarpal Joint of Left Thumb, Arthritis of Carpometacarpal Joint of Right Thumb
Interventions
Curcumin, Placebo
Drug
Lead sponsor
Brent DeGeorge
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Jul 22, 2026, 10:21 PM EDT
Completed Not applicable Interventional

Suture Fixation System Versus Tendonous Reconstruction in Carpometacarpal (CMC) Arthroplasty

NCT01121874
View directory record Official record
Conditions
Thumb Carpometacarpal Arthritis
Interventions
Ligament reconstruction with suture fixation system, Ligament Reconstruction with Tendon Interposition (LRTI)
Procedure
Lead sponsor
J&M Shuler
Industry
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 14, 2018 · Synced Jul 22, 2026, 10:21 PM EDT
Recruiting Phase 2 Interventional

Randomized Placebo Controlled Study of Triamcinolone Acetonide Extended Release Injection for Thumb (CMC) Osteoarthritis

NCT06237153
View directory record Official record
Conditions
Carpometacarpal (CMC) Osteoarthritis
Interventions
Triamcinolone Acetonide extended release suspension
Drug
Lead sponsor
Marie Badalamente
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Jan 31, 2024 · Synced Jul 22, 2026, 10:21 PM EDT
Completed Not applicable Interventional Results available

Pulsed Electromagnetic Field (PEMF) Therapy in Thumb CMC Arthritis

NCT05315297
View directory record Official record
Conditions
Thumb Osteoarthritis
Interventions
PEMF device, Sham PEMF device
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Aug 2, 2025 · Synced Jul 22, 2026, 10:21 PM EDT
Completed Phase 4 Interventional

Use of FlexHD as Post Trapeziectomy Spacer

NCT01998594
View directory record Official record
Conditions
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Interventions
Arthroplasty
Procedure
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 6, 2019 · Synced Jul 22, 2026, 10:21 PM EDT
Recruiting Not applicable Interventional

Woodcasting Versus Thermoplast Splint in CMC Arthroplasty

NCT06876350
View directory record Official record
Conditions
Carpometacarpal (CMC) Joint Arthritis
Interventions
Woodcasting Splint, Control (Standard treatment)
Other
Lead sponsor
Foundation for Orthopaedic Research and Education
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Mar 16, 2025 · Synced Jul 22, 2026, 10:21 PM EDT
Not listed Not applicable Interventional

Psychosocial Factors a Prognostic Study of Pain in Patients With CMC Osteoarthritis

NCT03821298
View directory record Official record
Conditions
Pain, Osteoarthritis
Interventions
Standard of Care Hand Therapy
Other
Lead sponsor
Gannon University
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Ruskin, Florida
Source: ClinicalTrials.gov public record
Updated Jul 30, 2019 · Synced Jul 22, 2026, 10:21 PM EDT
Completed Not applicable Interventional Results available

LRTI vs Internal Brace for CMC OA

NCT03971188
View directory record Official record
Conditions
Thumb Carpometacarpal Osteoarthritis
Interventions
Trapeziectomy with Internal Brace
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
50 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
3
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 5, 2025 · Synced Jul 22, 2026, 10:21 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Oval-8 Splinting Versus Standardized Treatment With Tee Pee or Forearm Based Thumb Spica Splinting

NCT02266095
View directory record Official record
Conditions
Carpometacarpal (CMC) Joint Arthritis
Interventions
Oval-8 Splint, Tee Pee Splint, Forearm Based Splint
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 3, 2016 · Synced Jul 22, 2026, 10:21 PM EDT
Completed No phase listed Observational

CMC Arthritis - Neoprene Vs. Thermoplast Short Opponens Splinting

NCT00438763
View directory record Official record
Conditions
Carpometacarpal Thumb Arthritis
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 26, 2013 · Synced Jul 22, 2026, 10:21 PM EDT
Recruiting Not applicable Interventional

Trapeziectomy and Suture Suspensionplasty for Thumb Carpometacarpal Arthritis - Is In-Clinic Therapy Needed?

NCT06820528
View directory record Official record
Conditions
CMC Arthritis, Occupational Therapy, Hand Arthritis
Interventions
Occupational Therapy, Home Exercise Program
Behavioral
Lead sponsor
Julie Nuelle
Other
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Jul 22, 2026, 10:21 PM EDT