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Showing 1–21 of 21 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Calcium Pyrophosphate Deposition Disease Clear all
Recruiting Not applicable Interventional

Pectoralis Minor Release Versus Non-release in RSA

NCT06292169
View directory record Official record
Conditions
Reverse Total Shoulder Arthroplasty, Rotator Cuff Tear Arthropathy, Advanced Glenohumeral Osteoarthritis
Interventions
Pectoralis Minor Release, RSA
Procedure
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Sep 22, 2026, 10:55 AM EDT
Not listed Not applicable Interventional

Subscapularis Repair in Reverse Shoulder Arthroplasty

NCT05438914
View directory record Official record
Conditions
Rotator Cuff Tear Arthropathy
Interventions
Repair of the subscapularis
Device
Lead sponsor
Arthrex, Inc.
Industry
Eligibility
18 Years to 100 Years
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
6
States / cities
Phoenix, Arizona • Denver, Colorado • Medford, Oregon + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 29, 2024 · Synced Sep 22, 2026, 10:55 AM EDT
Completed Early Phase 1 Interventional Results available

Effect of Probenecid on Synovial Fluid ATP Levels in CPPD

NCT02243631
View directory record Official record
Conditions
Calcium Pyrophosphate Deposition Disease
Interventions
Probenecid
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 99 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 25, 2022 · Synced Sep 22, 2026, 10:55 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Abduction Brace Versus Antirotation Sling for Immobilization Following Reverse Shoulder Arthroplasty and Rotator Cuff Repair

NCT03488433
View directory record Official record
Conditions
Rotator Cuff Tear Arthropathy, Rotator Cuff Tear
Interventions
Abduction brace, Antirotation sling
Device
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 18, 2019 · Synced Sep 22, 2026, 10:55 AM EDT
Active, not recruiting Not applicable Interventional

Sling vs No Sling After Reverse Total Shoulder Arthroplasty

NCT06092996
View directory record Official record
Conditions
Shoulder Disease, Rotator Cuff Tear Arthropathy, Shoulder Osteoarthritis
Interventions
Time of Sling Use
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 100 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Sep 22, 2026, 10:55 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Reverse Total Shoulder Arthroplasty: A Data Analysis on Patients Undergoing Reverse Total Shoulder Arthroplasty

NCT03617107
View directory record Official record
Conditions
Osteo Arthritis Shoulders, Proximal Humeral Fracture, Rotator Cuff Tear, Rotator Cuff Tear Arthropathy
Interventions
reverse total shoulder arthroplasty
Other
Lead sponsor
The Orthopaedic Research & Innovation Foundation
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Edgewood, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 24, 2019 · Synced Sep 22, 2026, 10:55 AM EDT
Completed Not applicable Interventional Results available

Effect of Ibuprofen on Postoperative Opiate Medication Use and Shoulder Functional Outcomes

NCT02588027
View directory record Official record
Conditions
Rotator Cuff Tear Arthropathy
Interventions
Ibuprofen, Placebo
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Sep 22, 2026, 10:55 AM EDT
Completed Not applicable Interventional Results available

Impact of Humeral Component Version on Outcomes Following RTSA

NCT03111147
View directory record Official record
Conditions
Rotator Cuff Tear Arthropathy
Interventions
0 degrees humeral component version, 30 degrees humeral component retroversion
Device
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 4, 2024 · Synced Sep 22, 2026, 10:55 AM EDT
Completed Not applicable Interventional

Local Infiltration Analgesia Vs. Interscalene Block in Total Shoulder Arthorplasty

NCT04415931
View directory record Official record
Conditions
Shoulder Osteoarthritis, Cuff Tear Arthropathy, Massive Rotator Cuff Tear
Interventions
Local infiltration analgesia, Interscalene block
Procedure
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 13, 2023 · Synced Sep 22, 2026, 10:55 AM EDT
Completed No phase listed Observational Results available

Prediction of Development of Scapular Notching Following Reverse Total Shoulder Arthroplasty

NCT02052466
View directory record Official record
Conditions
Osteoarthritis, Rotator Cuff Tear Arthropathy, Reverse Total Shoulder Arthroplasty, Scapular Notching
Interventions
Not listed
Lead sponsor
Eric Ricchetti
Other
Eligibility
Not listed
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 8, 2017 · Synced Sep 22, 2026, 10:55 AM EDT
Active, not recruiting No phase listed Observational

Database Retrieval for the Comprehensive Shoulder

NCT03409718
View directory record Official record
Conditions
Osteoarthritis of the Shoulder, Avascular Necrosis, Rheumatoid Arthritis, Prior Failed Revision, Correction of Functional Deformity, Fracture of Proximal End of Humerus, Cuff Tear Arthropathy
Interventions
Biomet Comprehensive Shoulder System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2026
U.S. locations
1
States / cities
Towson, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Sep 22, 2026, 10:55 AM EDT
Withdrawn Not applicable Interventional

Effect of Postop Rehab Methods on Outcomes Following Reverse Shoulder Arthroplasty

NCT04285606
View directory record Official record
Conditions
Rotator Cuff Tear Arthropathy, Shoulder Osteoarthritis
Interventions
Patient-led rehab with short immobilization
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 20, 2022 · Synced Sep 22, 2026, 10:55 AM EDT
Completed Not applicable Interventional

Home Exercise vs PT for Reverse Total Shoulder Arthroplasty

NCT03719859
View directory record Official record
Conditions
Shoulder Arthritis, Rotator Cuff Tear Arthropathy
Interventions
Physical Therapy, Home Therapy
Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
7
States / cities
Denver, Colorado • Washington D.C., District of Columbia • Chicago, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 21, 2025 · Synced Sep 22, 2026, 10:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Telerehabilitation After Shoulder Arthroplasty

NCT05499728
View directory record Official record
Conditions
Arthritis Shoulder Glenohumoral Joint, Rotator Cuff Tear Arthropathy, Arthropathy Shoulder
Interventions
Telerehabilitation; physical therapy via telecommunication device (i.e. online video conferencing)
Other
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Sep 22, 2026, 10:55 AM EDT
Completed No phase listed Observational

The Effects of Platelet Rich Plasma on the Integrity of Rotator Cuff Repair

NCT01424969
View directory record Official record
Conditions
Rotator Cuff Tear Arthropathy
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
50 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 13, 2014 · Synced Sep 22, 2026, 10:55 AM EDT
Recruiting Phase 2 Interventional

Colchicine to Reduce Your SympToms And Lower Levels of Inflammation, Zeroing in on Effective CPPD Disease Treatment

NCT06855433
View directory record Official record
Conditions
CPPD - Calcium Pyrophosphate Deposition Disease
Interventions
Colchicine Pill, Placebo
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
40 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
5
States / cities
Birmingham, Alabama • Los Angeles, California • Boston, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 20, 2026 · Synced Sep 22, 2026, 10:55 AM EDT
Not listed Not applicable Interventional

Impact of Glenosphere Size on Range of Motion in Female Patients Undergoing Reverse Shoulder Arthroplasty

NCT04093804
View directory record Official record
Conditions
Rotator Cuff Tear Arthropathy, Massive Irreparable Rotator Cuff Tear
Interventions
Glenosphere size for Reverse Shoulder Arthroplasty
Device
Lead sponsor
Fondren Orthopedic Group L.L.P.
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 17, 2019 · Synced Sep 22, 2026, 10:55 AM EDT
Completed No phase listed Observational

Functional and Radiographic Outcomes After Shoulder Surgery

NCT01405781
View directory record Official record
Conditions
Shoulder Pain, Osteoarthritis of Glenohumeral Joint, Rotator Cuff Tear Arthropathy
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
1,034 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2024
U.S. locations
2
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 12, 2025 · Synced Sep 22, 2026, 10:55 AM EDT
Recruiting No phase listed Observational

Exactech Shoulder Post Market Clinical Follow-up Study

NCT05603728
View directory record Official record
Conditions
Osteo Arthritis Shoulders, Osteonecrosis, Rotator Cuff Tears, Rotator Cuff Tear Arthropathy, Ankylosing Spondylitis, Post-traumatic Osteoarthritis, Rheumatoid Arthritis, Fracture, Infections
Interventions
Not listed
Lead sponsor
Exactech
Industry
Eligibility
21 Years and older
Enrollment
20,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2031
U.S. locations
24
States / cities
Laguna Woods, California • Redwood City, California • Stockton, California + 20 more
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Sep 22, 2026, 10:55 AM EDT
Recruiting No phase listed Observational

Perform Humeral System Study

NCT05067543
View directory record Official record
Conditions
Osteoarthritis Shoulder, Avascular Necrosis, Post-traumatic Arthrosis of Other Joints, Shoulder Region, Rotator Cuff Tear Arthropathy
Interventions
Tornier Perform Humeral - Stem
Device
Lead sponsor
Stryker Trauma and Extremities
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Timeline
2021 – 2037
U.S. locations
7
States / cities
Lexington, Kentucky • Eagan, Minnesota • Rochester, Minnesota + 4 more
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 22, 2026, 10:55 AM EDT
Recruiting Phase 4 Interventional

Bioinductive Patch for Full-Thickness Rotator Cuff Tears

NCT05439850
View directory record Official record
Conditions
Rotator Cuff Tears, Rotator Cuff Tear Arthropathy
Interventions
arthroscopic rotator cuff repair, Bioinductive implant, Ultrasound Imaging
Procedure · Biological · Diagnostic Test
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 22, 2026, 10:55 AM EDT