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ClinicalTrials.gov public records Last synced Oct 22, 2026, 2:23 PM EDT

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Showing 1–24 of 292 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Calculi Clear all
Completed Not applicable Interventional

Night Time Use of Thiazide Diuretics for Improved Reduction in Stone Risk in Stone Formers With Elevated Urine Calcium

NCT02711670
View directory record Official record
Conditions
Kidney Stones
Interventions
chlorthalidone, Hydrochlorothiazide
Drug
Lead sponsor
VA New York Harbor Healthcare System
Federal
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 27, 2023 · Synced Oct 22, 2026, 2:23 PM EDT
Recruiting Phase 1Phase 2 Interventional

CB-103 With Either Lenvatinib or Abemaciclib in Patients With NOTCH ACC

NCT05774899
View directory record Official record
Conditions
Adenoid Cystic Carcinoma, Metastatic Adenoid Cystic Carcinoma, Recurrent Adenoid Cystic Carcinoma
Interventions
CB-103, Abemaciclib, Lenvatinib
Drug
Lead sponsor
Michael J. Dennis, MD
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 22, 2026, 2:23 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Oxalate Formation From Ascorbic Acid

NCT04603898
View directory record Official record
Conditions
Kidney Stone
Interventions
Low Oxalate Diet, Carbon-13 Ascorbic Acid Oral Load
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 22, 2026, 2:23 PM EDT
Recruiting Early Phase 1 Interventional

NSAIDs Stent Study

NCT03638999
View directory record Official record
Conditions
Ureteral Stent Placement, Kidney Stone
Interventions
Ketorolac Trometamol 30Mg/1mL Injection, Normal saline
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Oct 22, 2026, 2:23 PM EDT
Recruiting Not applicable Interventional

FANS vs CVAC for Medium to Large Stones

NCT07514351
View directory record Official record
Conditions
Kidney Stones, Nephrolithiasis
Interventions
ureteroscopy, CVAC
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 22, 2026, 2:23 PM EDT
Completed Phase 1 Interventional

Use of Tolvaptan to Reduce Urinary Supersaturation: a Pilot Proof of Principle Study

NCT02096965
View directory record Official record
Conditions
Nephrolithiasis, Calcium Oxalate, Nephrolithiasis, Calcium Phosphate
Interventions
Tolvaptan, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 30, 2016 · Synced Oct 22, 2026, 2:23 PM EDT
Completed Phase 4 Interventional Results available

Tamsulosin for Urolithiasis in the Emergency Dept

NCT00382265
View directory record Official record
Conditions
Ureterolithiases
Interventions
tamsulosin, Placebo
Drug · Other
Lead sponsor
Andrew Meltzer
Other
Eligibility
18 Years and older
Enrollment
512 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2017
U.S. locations
4
States / cities
Birmingham, Alabama • Washington D.C., District of Columbia • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 10, 2018 · Synced Oct 22, 2026, 2:23 PM EDT
Completed Not applicable Interventional

Ultrasound Imaging of Kidney Stones and Lithotripsy

NCT02214836
View directory record Official record
Conditions
Kidney Stones, Nephrolithiasis, Urolithiasis, Ureter Stones
Interventions
Verasonics Data Acquisition System (VDAS)
Device
Lead sponsor
University of Washington
Other
Eligibility
21 Years and older
Enrollment
219 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 22, 2026, 2:23 PM EDT
Not listed No phase listed Observational

Interventional Endoscopy Database for Pancreatico-biliary, Gastrointestinal and Esophageal Disorders

NCT01438385
View directory record Official record
Conditions
Ampullary Cancer, Duodenal Cancer, Bile Duct Cancer, Bile Duct Disorders, Gallstones, Obstructive Jaundice, Pancreatic Disorders (Noncancerous), Colorectal Cancer, Esophageal Cancer, Barrett's Esophagus, Gastric Malignancies, Pancreatic Cancer, Pediatric Gastroenterology, Cholangiocarcinoma, Pancreatic Pseudocysts, Acute and Chronic Pancreatitis, Recurrent Pancreatitis, Cholangitis, Bile Leak, Biliary Strictures, Pancreatic Divisum, Biliary and Pancreatic Stones, Choledocholithiasis
Interventions
Interventional Endoscopy
Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
12,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 20, 2017 · Synced Oct 22, 2026, 2:23 PM EDT
Active, not recruiting Not applicable Interventional

Methocarbamol vs Oxybutynin for Management of Pain and Discomfort S/P Ureteroscopy Procedure

NCT05100017
View directory record Official record
Conditions
Kidney Calculi, Kidney Diseases, Nephrolithiasis, Urolithiasis, Ureteral Diseases, Ureteral Calculi
Interventions
Methocarbamol, Oxybutynin
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 80 Years
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 22, 2026, 2:23 PM EDT
Withdrawn Not applicable Interventional

Hybrid Transvaginal-Transabdominal Endoscopic Surgery

NCT01039129
View directory record Official record
Conditions
Gallstones, Appendicitis, Pelvic Pain
Interventions
Endoscopic Cholecystectomy, Endoscopic Appendectomy, Endoscopic Peritoneoscopy
Procedure
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years to 60 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 21, 2015 · Synced Oct 22, 2026, 2:23 PM EDT
Not yet recruiting No phase listed Observational

Modified SOLTIVE Study

NCT07838077
View directory record Official record
Conditions
Calculi, Renal, Calculi, Urinary, Benign Prostatic Hyperplasia
Interventions
SOLTIVE Premium SuperPulsed Laser System
Device
Lead sponsor
Olympus Corporation of the Americas
Industry
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 22, 2026, 2:23 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Meditation Effects on Discomfort, Pain InTerference, and AnxieTy After urEteroscopy

NCT06783946
View directory record Official record
Conditions
Kidney Stone, Pain, Postoperative, Anxiety Postoperative
Interventions
Meditation
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
12 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Oct 22, 2026, 2:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

ToothWave Calculus Reduction and Accumulation Prevention Study

NCT04596761
View directory record Official record
Conditions
Gingivitis, Plaque, Calculus, Dental
Interventions
RF-utilizing powered toothbrush, Control placebo with no RF
Device
Lead sponsor
Home Skinovations Ltd.
Industry
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 23, 2021 · Synced Oct 22, 2026, 2:23 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Oxalate-Driven Host Responses in Kidney Stone Disease

NCT05417568
View directory record Official record
Conditions
Kidney Stones
Interventions
Low Oxalate Diet, High Oxalate Diet
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 60 Years
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 15, 2026 · Synced Oct 22, 2026, 2:23 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Study Of The Safety And Pharmacokinetics Of CE-326,597 In Patients With Asymptomatic Gallstones

NCT00576589
View directory record Official record
Conditions
Obesity
Interventions
CE-326,597, Placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 65 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
12
States / cities
Anniston, Alabama • Phoenix, Arizona • Anaheim, California + 8 more
Source: ClinicalTrials.gov public record
Updated Jan 18, 2010 · Synced Oct 22, 2026, 2:23 PM EDT
Completed Not applicable Interventional

ESWL Versus SOPIL for Treatment of Pancreatic Duct Stones

NCT04158297
View directory record Official record
Conditions
Chronic Pancreatitis, Pancreatic Duct Stone
Interventions
ESWL vs SOPIL
Procedure
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 15, 2025 · Synced Oct 22, 2026, 2:23 PM EDT
Completed Early Phase 1 Interventional

Effect of a High Citrate Beverage on Urine Chemistry in Urinary Stone Disease

NCT04697706
View directory record Official record
Conditions
Urinary Stone
Interventions
Moonstone, Water
Dietary Supplement · Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 6, 2021 · Synced Oct 22, 2026, 2:23 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Ureteroscopic Laser Modality on Total Lasing Time and Total Energy in Patients With Large, Dense Renal Calculi

NCT05869890
View directory record Official record
Conditions
Renal Calculi
Interventions
MOSES laser system
Device
Lead sponsor
Albany Medical College
Other
Eligibility
18 Years to 80 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Feb 21, 2025 · Synced Oct 22, 2026, 2:23 PM EDT
Terminated Not applicable Interventional Results available

MOSES Lithotripsy Technology Applied to Stone Fragmentation During Ureteroscopy

NCT03995758
View directory record Official record
Conditions
Kidney Calculi
Interventions
MOSES
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 4, 2025 · Synced Oct 22, 2026, 2:23 PM EDT
Recruiting Early Phase 1 Interventional

SGLT2i in Kidney Stones

NCT07055282
View directory record Official record
Conditions
Kidney Stones
Interventions
Empagliflozin (Jardiance®)
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 70 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 22, 2026, 2:23 PM EDT
Completed Not applicable Interventional Results available

Effect of Tamsulosin on Stone Expulsion and Pain Resolution in ED Patients With Ureterolithiasis

NCT00762424
View directory record Official record
Conditions
Kidney Stone
Interventions
Flowmax, placebo
Drug
Lead sponsor
WellSpan Health
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
York, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 17, 2014 · Synced Oct 22, 2026, 2:23 PM EDT
Terminated Not applicable Interventional

Mobile Health Platform for Surveillance of Kidney Stone

NCT05389982
View directory record Official record
Conditions
Stone, Kidney
Interventions
mHealth (GetWell), Standard Care
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Oct 22, 2026, 2:23 PM EDT
Completed Not applicable Interventional Results available

TCUPS- Tolvaptan Use in Cystinuria and Urolithiasis: A Pilot Study

NCT02538016
View directory record Official record
Conditions
Cystinuria
Interventions
Tolvaptan
Drug
Lead sponsor
Caleb Nelson
Other
Eligibility
12 Years to 29 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 10, 2020 · Synced Oct 22, 2026, 2:23 PM EDT