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Showing 1–24 of 203 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cancer Related Pain Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Defining TRPV4 Contribution of Schwann Cells to Oral Cancer Pain

NCT07095608
View directory record Official record
Conditions
Oral Cancer, Squamous Cell Carcinoma
Interventions
Pressure and stretch sensitivity testing
Behavioral
Lead sponsor
New York University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Sep 6, 2026, 5:32 AM EDT
Completed Not applicable Interventional

Pilot Trial of Opioid Taper Support

NCT01883882
View directory record Official record
Conditions
Chronic Non-cancer Pain
Interventions
opioid taper support
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 80 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 23, 2016 · Synced Sep 6, 2026, 5:32 AM EDT
Withdrawn Not applicable Interventional

Acupuncture for Mucositis Pain in Cancer Care

NCT00549835
View directory record Official record
Conditions
Mucositis, Pain, Leukemia
Interventions
Real Acupuncture, Sham Acupuncture
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 7, 2015 · Synced Sep 6, 2026, 5:32 AM EDT
Completed Not applicable Interventional

Pain Coping Skills for Colorectal Cancer Survivors

NCT02706301
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Telephone-Based Coping Skills Training (CST)
Behavioral
Lead sponsor
Duke University
Other
Eligibility
21 Years to 80 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 16, 2019 · Synced Sep 6, 2026, 5:32 AM EDT
Completed Not applicable Interventional Results available

STAMP+CBT mHealth for Cancer Pain

NCT05403801
View directory record Official record
Conditions
Active Cancer, Active Cancer Treatment, Advanced Cancer, Palliative Care, Chronic Pain Due to Cancer
Interventions
STAMP+CBT application
Behavioral
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
3
States / cities
Boston, Massachusetts • Methuen, Massachusetts • Londonderry, New Hampshire
Source: ClinicalTrials.gov public record
Updated Dec 31, 2024 · Synced Sep 6, 2026, 5:32 AM EDT
Recruiting Not applicable Interventional

Cognitive Behavioral Theory-assisted Virtual Reality for Chronic CANcer Pain (VR-CAN)

NCT07318519
View directory record Official record
Conditions
Cancer, Cancer Pain, Chronic Cancer Pain
Interventions
VR-CAN prototype chronic cancer pain therapy -- virtual reality program delivering CBT for chronic cancer pain management, Active Control -- two-dimensional tablet-delivered intervention
Device
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 5, 2026 · Synced Sep 6, 2026, 5:32 AM EDT
Completed Phase 3 Interventional

Long-Term Safety Evaluation Of Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain

NCT00241722
View directory record Official record
Conditions
Bowel Dysfunction, Constipation
Interventions
Alvimopan, Placebo
Drug
Lead sponsor
Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Industry
Eligibility
18 Years and older
Enrollment
805 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
143
States / cities
Birmingham, Alabama • Huntsville, Alabama • Mobile, Alabama + 120 more
Source: ClinicalTrials.gov public record
Updated Aug 29, 2017 · Synced Sep 6, 2026, 5:32 AM EDT
Terminated Not applicable Interventional

Improving Outcomes and Lowering Costs by Integration of Primary Care Providers and Pain Medicine Physicians for Pain Pts

NCT02484937
View directory record Official record
Conditions
Back Pain, Chronic Pain, Pain, Intractable
Interventions
Group 2 (PCP Treatment), Group 1 (PMS Treatment)
Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 28, 2022 · Synced Sep 6, 2026, 5:32 AM EDT
Completed Phase 2 Interventional Results available

Phase 2 Randomized, Double-Blind, Placebo-Controlled, Parallel Group Trial of Linaclotide Administered to Patients With Opioid-Induced Constipation Receiving Chronic Opioid Treatment for Non-Cancer Pain

NCT02270983
View directory record Official record
Conditions
Opioid-Induced Constipation
Interventions
Linaclotide 145 micrograms, Linaclotide 290 micrograms, Placebo
Drug
Lead sponsor
Forest Laboratories
Industry
Eligibility
18 Years and older
Enrollment
254 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
77
States / cities
Anniston, Alabama • Foley, Alabama • Phoenix, Arizona + 67 more
Source: ClinicalTrials.gov public record
Updated Apr 7, 2019 · Synced Sep 6, 2026, 5:32 AM EDT
Recruiting Not applicable Interventional

Stereotactic MRI-guided Focused Ultrasound Mesencephalotomy

NCT07405645
View directory record Official record
Conditions
Head Neck Cancer, Squamous Cell Cancer of Head and Neck (SCCHN), Cancer Pain
Interventions
ExAblate Neuro
Device
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
6
States / cities
Boston, Massachusetts • New York, New York • Portland, Oregon + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Sep 6, 2026, 5:32 AM EDT
Completed Not applicable Interventional

Virtual Reality for Cancer Pain Management

NCT04572074
View directory record Official record
Conditions
Cancer, Cancer Pain
Interventions
Guided imagery, Virtual reality
Other
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Dec 4, 2022 · Synced Sep 6, 2026, 5:32 AM EDT
Completed No phase listed Observational

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care

NCT01431326
View directory record Official record
Conditions
Adenovirus, Anesthesia, Anxiety, Anxiolysis, Autism, Autistic Disorder, Bacterial Meningitis, Bacterial Septicemia, Benzodiazepine, Bipolar Disorder, Bone and Joint Infections, Central Nervous System Infections, Convulsions, Cytomegalovirus Retinitis, Early-onset Schizophrenia Spectrum Disorders, Epilepsy, General Anesthesia, Gynecologic Infections, Herpes Simplex Virus, Infantile Hemangioma, Infection, Inflammation, Inflammatory Conditions, Intra-abdominal Infections, Lower Respiratory Tract Infections, Migraines, Pain, Pneumonia, Schizophrenia, Sedation, Seizures, Skeletal Muscle Spasms, Skin and Skin-structure Infections, Treatment-resistant Schizophrenia, Urinary Tract Infections, Withdrawal, Sepsis, Gram-negative Infection, Bradycardia, Cardiac Arrest, Cardiac Arrhythmia, Staphylococcal Infections, Nosocomial Pneumonia, Neuromuscular Blockade, Methicillin Resistant Staphylococcus Aureus, Endocarditis, Neutropenia, Headache, Fibrinolytic Bleeding, Pulmonary Arterial Hypertension, CMV Retinitis, Hypertension, Chronic Kidney Diseases, Hyperaldosteronism, Hypokalemia, Heart Failure, Hemophilia, Heavy Menstrual Bleeding, Insomnia
Interventions
The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:
Drug
Lead sponsor
Daniel Benjamin
Other
Eligibility
Up to 21 Years
Enrollment
3,520 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2019
U.S. locations
43
States / cities
Anchorage, Alaska • Little Rock, Arkansas • La Jolla, California + 37 more
Source: ClinicalTrials.gov public record
Updated Sep 5, 2023 · Synced Sep 6, 2026, 5:32 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Open-Label Extension to Evaluate the Long-Term Safety, Tolerability and Analgesic Efficacy

NCT00904280
View directory record Official record
Conditions
Cancers, Pain, Lower Back Pain
Interventions
Oxymorphone ER
Drug
Lead sponsor
Endo USA Inc., a Keenova Therapeutics Company
Industry
Eligibility
18 Years to 75 Years
Enrollment
239 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2003
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated May 18, 2009 · Synced Sep 6, 2026, 5:32 AM EDT
Recruiting Phase 2 Interventional

Efficacy and Safety Study of Halneuron in the Treatment of Chemotherapy-Induced Neuropathic Pain

NCT06848348
View directory record Official record
Conditions
Chemotherapy Induced Neuropathic Pain, Chemotherapy Induced Pain Neuropathy, Chemotherapy Induced Pain
Interventions
Halneuron, Placebo, Halneuron (Open Label Extension)
Drug
Lead sponsor
Dogwood Therapeutics Inc.
Industry
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
25
States / cities
Sheffield, Alabama • Glendale, Arizona • Phoenix, Arizona + 21 more
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 6, 2026, 5:32 AM EDT
Completed Not applicable Interventional

Randomized Controlled Trial of Virtual Reality Assisted Guided Imagery (VRAGI) for Pain in Advanced Cancer Patients.

NCT05348174
View directory record Official record
Conditions
Cancer Pain, Oncology, Virtual Reality, Depression, Anxiety
Interventions
Virtual Reality Assisted Guided Imagery (VRAGI)
Behavioral
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years to 65 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
3
States / cities
Clemson, South Carolina • Columbia, South Carolina • Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 18, 2025 · Synced Sep 6, 2026, 5:32 AM EDT
Completed Not applicable Interventional

The First Therapeutic Intervention in Malignant Pleural Effusion Trial

NCT00896285
View directory record Official record
Conditions
Malignant Pleural Effusion, Pleural Effusion
Interventions
Large bore chest drain + NSAID based analgesic regimen, Small bore chest drain + NSAID based analgesic regimen, Large bore chest drain + opiate based analgesic regimen, Small bore chest drain + opiate based analgesic regimen
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 19, 2015 · Synced Sep 6, 2026, 5:32 AM EDT
Completed Phase 3 Interventional

Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain

NCT00256932
View directory record Official record
Conditions
Bowel Dysfunction, Constipation
Interventions
alvimopan, Placebo
Drug
Lead sponsor
Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Industry
Eligibility
18 Years and older
Enrollment
518 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
137
States / cities
Birmingham, Alabama • Calera, Alabama • Muscle Shoals, Alabama + 114 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2015 · Synced Sep 6, 2026, 5:32 AM EDT
Completed Not applicable Interventional

Improving Cancer Pain Management Using AHCPR Cancer Pain Guidelines

NCT00012896
View directory record Official record
Conditions
Cancers, Pain
Interventions
Telephone Care + Educational (AV Materials)
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
Not listed
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2004
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 6, 2015 · Synced Sep 6, 2026, 5:32 AM EDT
Completed Not applicable Interventional

Acupressure for Children in Treatment for a Childhood Cancer

NCT03313193
View directory record Official record
Conditions
Treatment-Related Cancer
Interventions
Acupressure for Children in Treatment for a Childhood Cancer
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
5 Years to 24 Years
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 10, 2019 · Synced Sep 6, 2026, 5:32 AM EDT
Terminated Phase 3 Interventional

Fentanyl Transdermal Matrix Patch ZR-02-01 to Treat Moderate to Severe Cancer Pain

NCT00126789
View directory record Official record
Conditions
Pain, Cancer
Interventions
Fentanyl Transdermal Matrix Patch ZR-02-01
Drug
Lead sponsor
ZARS Pharma Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
2
States / cities
Loma Linda, California • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 4, 2012 · Synced Sep 6, 2026, 5:32 AM EDT
Completed Not applicable Interventional

Balancing Method for Pain Related to Advanced Cancer

NCT04176575
View directory record Official record
Conditions
Pain, Cancer, Metastatic Cancer, Invasive Cancer
Interventions
Acupuncture
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 23, 2024 · Synced Sep 6, 2026, 5:32 AM EDT
Completed Phase 3 Interventional Results available

Sativex® for Relieving Persistent Pain in Participants With Advanced Cancer

NCT01262651
View directory record Official record
Conditions
Pain, Advanced Cancer
Interventions
Nabiximols, Placebo (GA-0034)
Drug
Lead sponsor
GW Pharmaceuticals Ltd
Industry
Eligibility
18 Years and older
Enrollment
397 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
25
States / cities
Phoenix, Arizona • El Cajon, California • Gilroy, California + 19 more
Source: ClinicalTrials.gov public record
Updated Apr 22, 2018 · Synced Sep 6, 2026, 5:32 AM EDT
Completed Not applicable Interventional

Reiki Therapy to Improve Key Symptoms in Integrative Oncology Clinic (REIKI)

NCT06354049
View directory record Official record
Conditions
Cancer Pain, Oncology Pain
Interventions
Reiki
Other
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years to 89 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Sep 6, 2026, 5:32 AM EDT
Completed Phase 2 Interventional

Effects of Pet Therapy on Pain in Cancer Patients

NCT00431639
View directory record Official record
Conditions
Cancer
Interventions
Animal Assisted Therapy
Behavioral
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years to 110 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 10, 2019 · Synced Sep 6, 2026, 5:32 AM EDT