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Showing 1–24 of 53 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Vaping THC From Electronic Cigarettes

NCT02955329
Conditions
Marijuana Dependence
Interventions
Nicotine, Cannabis, PAX Loose Leaf Vaporizer
Drug · Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 70 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
San Francisco, California
Conditions
Cigarette Smoking-Related Carcinoma
Interventions
Non-Interventional Study
Other
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years to 30 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Buffalo, New York
Conditions
Cannabis Use, Tobacco Use Disorder, Drug Use Disorder
Interventions
N-Acetyl cysteine, Placebo comparator, Cognitive behavioral therapy (CBT)
Drug · Other · Behavioral
Lead sponsor
Ellen Herbst
Other
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
San Francisco, California
Conditions
Perinatal, Cannabis Use, Tobacco Use, Smoking Cessation
Interventions
Perinatal smoking cessation treatment and maintenance sessions
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Tobacco Use Disorder, Cannabis Use Disorder
Interventions
Varenicline, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Effects of Dronabinol (Oral THC) on Cannabis Use

NCT01394185
Conditions
Marijuana Smoking
Interventions
Dronabinol 120mg/day, Placebo, Dronabinol 240mg/day
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Not applicable Interventional Accepts healthy volunteers

THC Crossover Study

NCT04429568
Conditions
THC, Cannabis, Cannabis Smoking, Cannabis Use, Unspecified, Cigarette Smoking, Tobacco Use, Nicotine Dependence, Nicotine Withdrawal, Cardiovascular Risk Factor
Interventions
Smoked Cannabis, Vaped Cannabis, Tobacco Cigarette
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
2
States / cities
San Francisco, California
Recruiting Phase 1 Interventional Accepts healthy volunteers

Effect of Cannabis on Cigarette Use Behavior

NCT06609083
Conditions
Cannabis Use, Tobacco Use, Cigarette Smoking
Interventions
THC 30mg, THC 5mg, THC 0mg, Cigarette Full Nicotine, Cigarette Reduced Nicotine
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Baltimore, Maryland
Completed No phase listed Observational Accepts healthy volunteers

Screening Protocol for Research Participants

NCT01010620
Conditions
Schizophrenia, Substance Abuse, Cocaine Abuse, Tobacco Use Disorder
Interventions
Various Screening psychiatric and medical assessments
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 64 Years
Enrollment
523 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2019
U.S. locations
1
States / cities
Catonsville, Maryland
Recruiting Phase 1 Interventional Accepts healthy volunteers

Effect of Cannabis on E-Cigarette Use Behavior

NCT06609109
Conditions
Cannabis Use, Tobacco Use, Electronic Cigarette Use
Interventions
THC High Dose, THC Low Dose, THC 0mg, E-Cigarette Full Nicotine, E-Cigarette Placebo Nicotine
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Alcohol Drinking, Cigarette Smoking, Marijuana Smoking
Interventions
Project CHOICE
Behavioral
Lead sponsor
RAND
Other
Eligibility
11 Years to 15 Years
Enrollment
6,455 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Conditions
HIV Positive, Marijuana Smoking
Interventions
Not listed
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 70 Years
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Detroit, Michigan
Conditions
Alcohol Drinking, Marijuana Smoking
Interventions
brief counseling
Behavioral
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
18 Years and older
Enrollment
554 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Providence, Rhode Island
Completed Not applicable Interventional Results available

Mobile Contingency Management for Marijuana and Tobacco Cessation

NCT02869451
Conditions
Cigarette Smoking, Marijuana Abuse
Interventions
bupropion, transdermal nicotine patch, Nicotine polacrilex, nicotine lozenge, counseling for marijuana and smoking cessation, mobile contingency management
Drug · Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 70 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers Results available

Project CheckUP: A Brief Behavioral Intervention for Quitline Callers Who Use Marijuana (MJ) and Tobacco

NCT04737772
Conditions
Smoking Cessation, Marijuana Use
Interventions
Behavioral: Quitline treatment as usual, QL Marijuana Check-Up intervention (QL-MJCU)
Behavioral
Lead sponsor
Consumer Wellness Solutions
Industry
Eligibility
21 Years and older
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Cannabis
Interventions
iTBS
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2029
U.S. locations
1
States / cities
Durham, North Carolina
Recruiting Not applicable Interventional Accepts healthy volunteers

Perceptual Influences From Smoking Cannabis: an Experimental Study

NCT06588582
Conditions
Cannabis Use, Stress
Interventions
Water Temperature Variation - WW, Water Temperature Variation - CW
Other
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
21 Years to 65 Years
Enrollment
166 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Boulder, Colorado
Completed Not applicable Interventional Accepts healthy volunteers Results available

Families With Substance Use and Psychosis: A Pilot Study

NCT04284813
Conditions
Psychosis, Substance Use, Substance Use Disorders, Family, Tobacco Use, Nicotine Use Disorder, Cigarette Smoking, Cannabis, Marijuana, Alcohol Use Disorder, Alcohol, Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Mental Disorder
Interventions
CRAFT-FT
Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Belmont, Massachusetts
Conditions
Vaping
Interventions
Social Media Intervention
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
13 Years to 21 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
San Francisco, California
Not listed Not applicable Interventional Accepts healthy volunteers

Guiding Good Choices for Health

NCT04040153
Conditions
Adolescent Substance Use
Interventions
Guiding Good Choices
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
11 Years to 12 Years
Enrollment
3,636 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
3
States / cities
Oakland, California • Aurora, Colorado • Detroit, Michigan
Conditions
Cannabis Dependence, Nicotine Dependence
Interventions
Cognitive Behavioral Therapy, Nicotine Replacement Therapy
Behavioral · Drug
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Belmont, Massachusetts
Conditions
THC, Cannabis, Cannabis Use, Cannabis Smoking, Tobacco Use, Vaping
Interventions
Cannabis, Nicotine, Pax Loose Leaf Vaporizer, Placebo Marijuana
Drug · Device · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
San Francisco, California
Suspended Not applicable Interventional Accepts healthy volunteers

Cannabis THC Potency, Metabolism, and Cognitive Impairment in Young Adults

NCT06077292
Conditions
Cannabis Use, THC, Marijuana Use, Cognitive Impairment, THC Vaping
Interventions
15% THC Potency Reduction, 35% THC Potency Reduction
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 25 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Francisco, California
Recruiting Phase 4 Interventional Accepts healthy volunteers

E-cigarette Cessation in Adults Who Co-use Cannabis

NCT06688539
Conditions
Nicotine Dependence, Tobacco Use Disorder
Interventions
Varenicline Pill, Contingency management, Counseling
Drug · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 40 Years
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
3
States / cities
Charleston, South Carolina • Lancaster, South Carolina • Pickens, South Carolina