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ClinicalTrials.gov public records Last synced Oct 21, 2026, 10:35 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 73–96 of 269 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Cannabis Use Disorders Clear all
Completed Phase 2 Interventional

CBD for the Treatment of Alcohol Use Disorder

NCT04873453
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Cannabidiol, Placebo
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
21 Years to 60 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced Oct 21, 2026, 10:35 PM EDT
Recruiting Not applicable Interventional

Integrated Treatment for Enhancing Growth in Recovery During Adolescence

NCT06395467
View directory record Official record
Conditions
Alcohol Use Disorder, Cannabis Use Disorder
Interventions
InTEGRA, MET/CBT
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
14 Years to 21 Years
Enrollment
294 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
Farmington, Connecticut • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 6, 2026 · Synced Oct 21, 2026, 10:35 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Cannabis Effects on Brain Morphology in Aging

NCT01874886
View directory record Official record
Conditions
Study Focuses on Brain Morphology and Cognition in Older Subjects
Interventions
Not listed
Lead sponsor
University of California, Los Angeles
Other
Eligibility
60 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 3, 2020 · Synced Oct 21, 2026, 10:35 PM EDT
Completed Not applicable Interventional

Peer Approaches to Substances in Early Psychosis Programs: A Pilot Study of a Peer-Led Intervention

NCT04517279
View directory record Official record
Conditions
Psychotic Disorders, Substance Use
Interventions
Peer Approach to Substances in Early Psychosis Programs, Usual Care Peer Services
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
15 Years to 32 Years
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
15
States / cities
Austin, Texas • Beaumont, Texas • Big Spring, Texas + 12 more
Source: ClinicalTrials.gov public record
Updated Dec 19, 2025 · Synced Oct 21, 2026, 10:35 PM EDT
Recruiting Phase 3 Interventional Accepts healthy volunteers

Cannabis-Tobacco Co-Use Treatment Study

NCT06883162
View directory record Official record
Conditions
Tobacco Use Disorder, Tobacco Use Cessation, Cannabis Use, Cannabis Use Disorder, Marijuana Use
Interventions
Varenicline, Counseling, Psychosocial modules
Drug · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Oct 21, 2026, 10:35 PM EDT
Completed Not applicable Interventional Results available

Mobile Contingency Management for Marijuana and Tobacco Cessation

NCT02869451
View directory record Official record
Conditions
Cigarette Smoking, Marijuana Abuse
Interventions
bupropion, transdermal nicotine patch, Nicotine polacrilex, nicotine lozenge, counseling for marijuana and smoking cessation, mobile contingency management
Drug · Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 70 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 7, 2020 · Synced Oct 21, 2026, 10:35 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Clinician Practice Companion to Address Youth Substance Use

NCT07725289
View directory record Official record
Conditions
Substance Use, Substance-Related Disorders, Adolescent Substance Use, Cannabis Use, Opioid Use Disorder, Drug Overdose, Overdose Prevention, Co-occurring Mental Health Conditions
Interventions
Practice Companion
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
14 Years to 24 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 21, 2026, 10:35 PM EDT
Completed Phase 4 Interventional Results available

Clozapine for Cannabis Use in Schizophrenia

NCT01639872
View directory record Official record
Conditions
Schizophrenia, Cannabis Abuse, Cannabis Dependence, Dual Diagnosis
Interventions
Clozapine, Risperidone
Drug
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 55 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
9
States / cities
Garden Grove, California • Oakland, California • Miami, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated May 5, 2020 · Synced Oct 21, 2026, 10:35 PM EDT
Completed Phase 2 Interventional Results available

Fatty Acid Amide Hydrolase (FAAH) Inhibitor Treatment of Cannabis Use Disorder (CUD)

NCT03386487
View directory record Official record
Conditions
Cannabis Use Disorder
Interventions
PF 04457845, Placebo Oral Tablet
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 60 Years
Enrollment
228 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
4
States / cities
New Haven, Connecticut • Baltimore, Maryland • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 14, 2024 · Synced Oct 21, 2026, 10:35 PM EDT
Completed Phase 2Phase 3 Interventional Results available

N-Acetylcysteine for Youth Cannabis Use Disorder

NCT03055377
View directory record Official record
Conditions
Cannabis Use Disorder
Interventions
N-acetyl cysteine, Placebo oral capsule
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
14 Years to 21 Years
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 17, 2024 · Synced Oct 21, 2026, 10:35 PM EDT
Completed Not applicable Interventional Results available

Impact of Reduced Cannabis Use on Functional Outcomes

NCT03681353
View directory record Official record
Conditions
Cannabis, Cannabis Use
Interventions
Mobile Contingency Management, active
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 5, 2021 · Synced Oct 21, 2026, 10:35 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Neural Correlates of Cannabis Use

NCT03104257
View directory record Official record
Conditions
Cannabis Dependence, Healthy
Interventions
[11-C]OMAR
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years
Enrollment
162 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 21, 2025 · Synced Oct 21, 2026, 10:35 PM EDT
Completed Phase 4 Interventional

Evaluation of Suvorexant for Reduction of Brain Reactivity in Patients With Cannabis Use Disorder (Pilot Study)

NCT06584942
View directory record Official record
Conditions
Cue-reactivity, Cannabis Use Disorder, Functional MRI, Orexin Antagonist
Interventions
Suvorexant
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 21, 2026, 10:35 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The Community Youth Development Study: A Test of Communities That Care

NCT01088542
View directory record Official record
Conditions
Substance Abuse, Juvenile Delinquency, Sexual Behavior, Criminal Behavior, Violence, Depression, Anxiety, Suicide, Sexually Transmitted Infection, Educational Attainment
Interventions
Communities That Care
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
10 Years and older
Enrollment
52,323 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 7, 2025 · Synced Oct 21, 2026, 10:35 PM EDT
Completed Not applicable Interventional

A Real-time, Contextual Intervention Using Mobile Technology to Reduce Marijuana Use in Youth

NCT01762696
View directory record Official record
Conditions
Marijuana Abuse
Interventions
MET, MOMENT
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
15 Years to 24 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
2
States / cities
Boston, Massachusetts • Jamaica Plain, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 12, 2016 · Synced Oct 21, 2026, 10:35 PM EDT
Completed Phase 4 Interventional Results available

N-Acetylcysteine for Smoking Cessation in Tobacco and Cannabis Co-Use

NCT04627922
View directory record Official record
Conditions
Cannabis Use, Tobacco Use Disorder, Drug Use Disorder
Interventions
N-Acetyl cysteine, Placebo comparator, Cognitive behavioral therapy (CBT)
Drug · Other · Behavioral
Lead sponsor
Ellen Herbst
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 21, 2026, 10:35 PM EDT
Completed No phase listed Observational

Consequences of Marijuana Use in HIV-infected Youth

NCT03927053
View directory record Official record
Conditions
Youth With HIV
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
21 Years to 28 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
2
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 13, 2023 · Synced Oct 21, 2026, 10:35 PM EDT
Terminated Phase 2 Interventional

Sex Differences in Neurobehavioral Response to THC

NCT07225777
View directory record Official record
Conditions
Cannabis Use Disorder
Interventions
Dronabinol, Placebo
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 45 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 21, 2026, 10:35 PM EDT
Recruiting Not applicable Interventional

Neuroimaging of Adolescent Cannabis Use Treatment

NCT07340554
View directory record Official record
Conditions
Cannabis Use, Cannabis Dependence, Cannabis Use Disorder, Cannabis Abuse, Cannabis Intoxication, Cannabis Smoking, Cannabis Withdrawal, Cannabis-Related Disorder, Cannabis Abuse, in Remission, Cannabis Abuse, Episodic Use, Marijuana, Marijuana Abuse, Marijuana Use, Marijuana Smoking, Marijuana Dependence, Marijuana User, Marijuana-Related Disorder, Marijuana Use Disorder, Addiction, Addiction, Substance, Substance Use, Substance Use Disorders, Substance Dependence, Substance Abuse, Substance Related Problem, Substance Abuse Drug Chronic
Interventions
Contingency Management, Elastic Net Regression
Behavioral · Device
Lead sponsor
Indiana University
Other
Eligibility
14 Years to 17 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 21, 2026, 10:35 PM EDT
Not listed Not applicable Interventional

Breathwork-assisted Treatment for Cannabis Use Disorder

NCT05219825
View directory record Official record
Conditions
Addiction, Substance Abuse, Cannabis Use Disorder, Cannabis Use, Cannabis Dependence, Cannabis Abuse
Interventions
Breathwork workshop
Behavioral
Lead sponsor
Elias Dakwar
Other
Eligibility
18 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 21, 2026, 10:35 PM EDT
Recruiting No phase listed Observational

Study of an Oral Fluid Testing Approach

NCT06891235
View directory record Official record
Conditions
Cannabis Use, Cannabis Intoxication, Cannabis Use Disorder
Interventions
Biologic testing for THC
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
18 Years to 30 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 21, 2026, 10:35 PM EDT
Not yet recruiting Early Phase 1 Interventional Accepts healthy volunteers

Lung Health and Breath Biomarkers: Acute Effects of Inhaled Cannabis

NCT07694466
View directory record Official record
Conditions
Cannabis Use, Tobacco, Biomarkers
Interventions
Cannabis (THC), Tobacco Cigarette
Drug
Lead sponsor
Hannah Harris
Other
Eligibility
18 Years to 55 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 21, 2026, 10:35 PM EDT
Not yet recruiting Not applicable Interventional

Applying Neuromodulation to Boost the Efficacy of Motivational Interviewing

NCT07787572
View directory record Official record
Conditions
Cannabis Use Disorder
Interventions
transcranial alternating current stimulation, sham transcranial alternating current stimulation, Motivational interviewing (MI)
Device · Behavioral
Lead sponsor
The Mind Research Network
Other
Eligibility
21 Years to 65 Years
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 21, 2026, 10:35 PM EDT
Completed No phase listed Observational Results available

Cannabis Use in Cancer Patients

NCT03617692
View directory record Official record
Conditions
Solid Tumor, Adult
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
21 Years to 100 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
2
States / cities
Aurora, Colorado • Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 11, 2024 · Synced Oct 21, 2026, 10:35 PM EDT