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ClinicalTrials.gov public records Last synced Sep 7, 2026, 11:34 AM EDT

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Showing 1–24 of 264 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cannabis-use Disorders Clear all
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Effects of Dronabinol (Oral THC) on Cannabis Use

NCT01394185
View directory record Official record
Conditions
Marijuana Smoking
Interventions
Dronabinol 120mg/day, Placebo, Dronabinol 240mg/day
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 2, 2017 · Synced Sep 7, 2026, 11:34 AM EDT
Completed Not applicable Interventional

Improving Brief Marijuana Interventions With a Behavioral Economic Supplement

NCT02837315
View directory record Official record
Conditions
Marijuana Use
Interventions
Brief Motivational Intervention (BMI), Substance-Free Activity Session (SFAS), Relaxation Session
Behavioral
Lead sponsor
University of Memphis
Other
Eligibility
18 Years and older
Enrollment
133 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated May 1, 2017 · Synced Sep 7, 2026, 11:34 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Neural Correlates of Cannabis Use

NCT03104257
View directory record Official record
Conditions
Cannabis Dependence, Healthy
Interventions
[11-C]OMAR
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years
Enrollment
162 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Sep 7, 2026, 11:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Gender-Responsive Drug Use Treatment for Juvenile Justice Girls

NCT02293057
View directory record Official record
Conditions
Drug Use
Interventions
VOICES Group, Girl Health Group
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
12 Years to 24 Years · Female only
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 22, 2020 · Synced Sep 7, 2026, 11:34 AM EDT
Completed Not applicable Interventional

Gender/Sex & CUD Remission

NCT04964739
View directory record Official record
Conditions
Cannabis Use Disorder, Mild, Cannabis Use Disorder, Moderate, Cannabis Use Disorder, Severe
Interventions
Cognitive Behavioral Therapy (CBT4CBT)
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Sep 7, 2026, 11:34 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Effects of Smoked Marijuana on Risk Taking and Decision Making Tasks

NCT00373399
View directory record Official record
Conditions
Marijuana Use Disorder
Interventions
Inactive Marijuana (0% THC), Low THC marijuana (1.8 %THC), High THC marijuana (3.9% THC)
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
21 Years to 45 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 18, 2018 · Synced Sep 7, 2026, 11:34 AM EDT
Completed Phase 2 Interventional Results available

Gabapentin for Bipolar & Cannabis Use Disorders

NCT03334721
View directory record Official record
Conditions
Bipolar I Disorder, Bipolar II Disorder, Cannabis Use Disorder, Substance Use Disorders
Interventions
Gabapentin, Placebo Oral Capsule
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 12, 2020 · Synced Sep 7, 2026, 11:34 AM EDT
Recruiting Not applicable Interventional

Targeting Insomnia to Improve Outcomes in Adults With Problematic Cannabis Use

NCT05814822
View directory record Official record
Conditions
Insomnia
Interventions
Cognitive Behavioral Therapy for insomnia (CBTi-CB-TM), Sleep Hygiene Education (SHE-TM)
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
21 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 7, 2026, 11:34 AM EDT
Completed Not applicable Interventional

Targeting Tobacco Cessation During Treatment for Cannabis Use Disorders

NCT01834794
View directory record Official record
Conditions
Cannabis Dependence
Interventions
MET/CBT/CM plus NRT
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
2
States / cities
Concord, New Hampshire • Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Jan 13, 2019 · Synced Sep 7, 2026, 11:34 AM EDT
Active, not recruiting Not applicable Interventional

Evaluation of a Brief Computerized and Smart Phone-based Intervention for Stress in Regular Cannabis Users

NCT06085222
View directory record Official record
Conditions
Cannabis Use Disorder
Interventions
Emotional Engagement Distress Tolerance Intervention, Health Education Intervention
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 30 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 7, 2026, 11:34 AM EDT
Completed Phase 2 Interventional Results available

Pharmacological Treatment of Comorbid Alcohol and Marijuana Withdrawal and Dependence

NCT02210195
View directory record Official record
Conditions
Cannabis Dependence, Alcohol Dependence, Cannabis Use Disorder, Alcohol Use Disorder
Interventions
aprepitant, Placebo, Manual-guided behavioral counseling
Drug · Behavioral
Lead sponsor
The Scripps Research Institute
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Aug 1, 2017 · Synced Sep 7, 2026, 11:34 AM EDT
Not yet recruiting Phase 1 Interventional

Cannabis and Opioid Use Disorder, Study 2

NCT07661446
View directory record Official record
Conditions
Opioid Use Disorders, Cannabis Use
Interventions
Inhaled Cannabis, Intranasal Opioid
Drug
Lead sponsor
University of Kentucky
Other
Eligibility
18 Years to 55 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Sep 7, 2026, 11:34 AM EDT
Not yet recruiting Early Phase 1 Interventional Accepts healthy volunteers

Research Investigating Drug Effects-2 (RiDE-2)

NCT06758596
View directory record Official record
Conditions
Cannabis Use, Substance Use Disorder (SUD), Healthy
Interventions
Placebo Oral Capsule, THC
Drug
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 21 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Sep 7, 2026, 11:34 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Skills for Talking About Cannabis for Families of Young Adults With Psychosis

NCT06961877
View directory record Official record
Conditions
Caregiver Burden, Cannabis Use, Expressed Emotion, Communications Skills
Interventions
Cannabis Conversation Skills for Families (CCSF)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced Sep 7, 2026, 11:34 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Emerging Adults Who Use Alcohol and Marijuana

NCT01473719
View directory record Official record
Conditions
Alcohol Use, Marijuana Use, Sexually Transmitted Infections
Interventions
motivational intervention, health education
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 25 Years
Enrollment
566 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 17, 2017 · Synced Sep 7, 2026, 11:34 AM EDT
Completed Phase 2 Interventional

Effect of PP-01 on Cannabis Withdrawal Syndrome

NCT05494437
View directory record Official record
Conditions
Cannabis Withdrawal
Interventions
PP-01 High Dose, PP-01 Low Dose, Placebo, Nabilone, Gabapentin
Combination Product · Drug
Lead sponsor
PleoPharma, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
18
States / cities
Glendale, California • Lemon Grove, California • Orange, California + 15 more
Source: ClinicalTrials.gov public record
Updated Aug 15, 2024 · Synced Sep 7, 2026, 11:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

TACUNA (Traditions and Connections for Urban Native Americans)

NCT04617938
View directory record Official record
Conditions
Opioid Use, Alcohol Drinking, Marijuana Use
Interventions
TACUNA plus Wellness Circle, Opioid Education Workshop
Behavioral
Lead sponsor
RAND
Other
Eligibility
18 Years to 25 Years
Enrollment
541 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
3
States / cities
Los Angeles, California • Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 7, 2026, 11:34 AM EDT
Completed Not applicable Interventional Results available

Screening to Augment Referral to Treatment- Project START

NCT01539525
View directory record Official record
Conditions
Alcohol Abuse, Tobacco Use Disorder, Marijuana Abuse, Substance-Related Disorders
Interventions
Motivational Interview, Treatment as Usual
Behavioral · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
439 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 13, 2017 · Synced Sep 7, 2026, 11:34 AM EDT
Not yet recruiting Not applicable Interventional

Transcranial Magnetic Stimulation for Adolescents and Young Adults With Cannabis Use Disorder

NCT07634835
View directory record Official record
Conditions
Cannabis Use, Cannabis Use Disorder
Interventions
Magstim SuperRapid2, Sham rTMS
Device
Lead sponsor
University of Minnesota
Other
Eligibility
15 Years to 21 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 7, 2026, 11:34 AM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Wayne State Warriors Marijuana Clinical Research Program: Cannabinoid Adjunct to Prolonged Exposure & Recovery

NCT06222268
View directory record Official record
Conditions
PTSD, Post Traumatic Stress Disorder, Suicide, Cannabis Use
Interventions
Cannabidiol (CBD) only, Placebo only, Delta-9-tetrahydrocannabinol (THC) only, THC:CBD 1:1
Drug
Lead sponsor
Leslie Lundahl
Other
Eligibility
18 Years to 60 Years
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 7, 2026, 11:34 AM EDT
Not listed Not applicable Interventional

Computer-delivered Psychosocial Intervention for Adolescent Substance Use Disorders

NCT00957775
View directory record Official record
Conditions
Substance-Related Disorders, Alcohol-Related Disorders, Marijuana Abuse
Interventions
Usual care, Computer-delivered ACRA
Behavioral
Lead sponsor
National Development and Research Institutes, Inc.
Other
Eligibility
12 Years to 18 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 11, 2009 · Synced Sep 7, 2026, 11:34 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning

NCT01730781
View directory record Official record
Conditions
Schizophrenia, Cannabis Dependence, Prodromal for Psychotic Illness, Family History of Alcoholism, Healthy Control, Opioid-use Disorder, Post Traumatic Stress Disorder
Interventions
[11-C]OMAR
Radiation
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years · Male only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 26, 2026 · Synced Sep 7, 2026, 11:34 AM EDT
Recruiting Not applicable Interventional

Cannabis Reduction and Functional Outcomes

NCT07218471
View directory record Official record
Conditions
Cannabis Use Disorder
Interventions
CBT4CBT (Computerized Cognitive Behavioral Therapy), Motivational Interviewing, Contingency Management
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Sep 7, 2026, 11:34 AM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Effect of Cannabis on E-Cigarette Use Behavior

NCT06609109
View directory record Official record
Conditions
Cannabis Use, Tobacco Use, Electronic Cigarette Use
Interventions
THC High Dose, THC Low Dose, THC 0mg, E-Cigarette Full Nicotine, E-Cigarette Placebo Nicotine
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Sep 7, 2026, 11:34 AM EDT