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ClinicalTrials.gov public records Last synced Oct 1, 2026, 7:12 AM EDT

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Showing 25–48 of 291 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Cardiac Arrest Circulatory Clear all
Enrolling by invitation No phase listed Observational

Long-term Follow-up Study of Gene Therapy for Arrhythmogenic Cardiomyopathy Due to a Plakophilin-2 Pathogenic Variant

NCT07050160
View directory record Official record
Conditions
Arrhythmogenic Cardiomyopathy, PKP2-ACM, PKP2-ARVC
Interventions
Not listed
Lead sponsor
Lexeo Therapeutics
Industry
Eligibility
18 Years to 67 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Oct 1, 2026, 7:12 AM EDT
Completed Not applicable Interventional Results available

Pragmatic Airway Resuscitation Trial

NCT02419573
View directory record Official record
Conditions
Cardiac Arrest
Interventions
Endotracheal Intubation, Laryngeal Tube (King)
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
3,004 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
6
States / cities
Birmingham, Alabama • Portland, Oregon • Pittsburgh, Pennsylvania + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 14, 2019 · Synced Oct 1, 2026, 7:12 AM EDT
Terminated Not applicable Interventional

Therapeutic Hypothermia After the Return of Spontaneous Circulation

NCT01617291
View directory record Official record
Conditions
Cardiac Arrest
Interventions
Induced therapeutic hypothermia
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Fresno, California
Source: ClinicalTrials.gov public record
Updated Feb 14, 2014 · Synced Oct 1, 2026, 7:12 AM EDT
Terminated No phase listed Observational

Evaluation of an Anti-Shivering Protocol Cardiac Arrest

NCT05264246
View directory record Official record
Conditions
Cardiac Arrest
Interventions
Not listed
Lead sponsor
Methodist Health System
Other
Eligibility
18 Years and older
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Oct 1, 2026, 7:12 AM EDT
Enrolling by invitation No phase listed Observational

Pre-hospital Ventilation Clinical Study

NCT05604430
View directory record Official record
Conditions
Altered Mental Status, Sepsis, Heart Failure, Hemorrhage, Respiratory Distress Syndrome, Adult, Cardiac Arrest
Interventions
731 Series Ventilator
Device
Lead sponsor
Zoll Medical Corporation
Industry
Eligibility
Not listed
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2030
U.S. locations
5
States / cities
Hartford, Connecticut • Baton Rouge, Louisiana • Uxbridge, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 1, 2026, 7:12 AM EDT
Completed Not applicable Interventional Results available

Early Warning System for Clinical Deterioration on General Hospital Wards

NCT01280942
View directory record Official record
Conditions
Escalation of Care, Cardiopulmonary Arrest, Respiratory Arrest, Severe Sepsis, Septic Shock
Interventions
EWS Nursing Alerts, Wireless Remote Sensor
Behavioral · Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
20,031 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 14, 2018 · Synced Oct 1, 2026, 7:12 AM EDT
Terminated Not applicable Interventional Results available

ACCESS to the Cardiac Cath Lab in Patients Without STEMI Resuscitated From Out-of-hospital VT/VF Cardiac Arrest

NCT03119571
View directory record Official record
Conditions
Cardiac Arrest Due to Underlying Cardiac Condition, Ventricular Fibrillation, Cardiopulmonary Arrest With Successful Resuscitation
Interventions
Initial CCL admission, Initial ICU admission
Procedure · Diagnostic Test
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 75 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
21
States / cities
Atlanta, Georgia • Indianapolis, Indiana • Ann Arbor, Michigan + 14 more
Source: ClinicalTrials.gov public record
Updated Jan 27, 2021 · Synced Oct 1, 2026, 7:12 AM EDT
Not listed No phase listed Observational

Prospective Study to Identify Patients at Risk of Dangerous Ventricular Arrhythmias

NCT00562757
View directory record Official record
Conditions
Sudden Cardiac Death
Interventions
Not listed
Lead sponsor
Harbinger Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
4
States / cities
Phoenix, Arizona • Wichita, Kansas • Boston, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 22, 2007 · Synced Oct 1, 2026, 7:12 AM EDT
Completed Not applicable Interventional Results available

Educational Videos to Address Racial Disparities in Implantable Cardioverter Defibrillator Therapy

NCT02819973
View directory record Official record
Conditions
Sudden Cardiac Death, Heart Failure
Interventions
Educational Video1, Educational Video 2, Usual Care 3
Other
Lead sponsor
Duke University
Other
Eligibility
21 Years and older
Enrollment
343 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
14
States / cities
San Francisco, California • Washington D.C., District of Columbia • Atlanta, Georgia + 11 more
Source: ClinicalTrials.gov public record
Updated Apr 21, 2021 · Synced Oct 1, 2026, 7:12 AM EDT
Recruiting Not applicable Interventional

Simulation Trial of Telemedical Support for Paramedics

NCT06441760
View directory record Official record
Conditions
Emergencies, Cardiopulmonary Arrest, Acute Respiratory Failure, Status Epilepticus
Interventions
Video teleconsultation, Audio support
Other
Lead sponsor
Boston Medical Center
Other
Eligibility
21 Years and older
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
9
States / cities
Los Angeles, California • Aurora, Colorado • New Haven, Connecticut + 6 more
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 1, 2026, 7:12 AM EDT
Completed Not applicable Interventional Results available

Acceptance and Mindfulness Based Exposure Therapy for Survivors of Cardiac Arrest

NCT04596891
View directory record Official record
Conditions
PTSD, Cardiac Arrest
Interventions
Psychotherapy
Behavioral
Lead sponsor
Research Foundation for Mental Hygiene, Inc.
Other
Eligibility
18 Years to 85 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Oct 1, 2026, 7:12 AM EDT
Recruiting No phase listed Observational

A Study to Assess Real-world Patient Characteristics and Clinical Course for Symptomatic Patients With PKP2-ACM

NCT06976606
View directory record Official record
Conditions
Arrhythmogenic Cardiomyopathy, PKP2-ACM, PKP2-ARVC
Interventions
Not listed
Lead sponsor
Lexeo Therapeutics
Industry
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
6
States / cities
Redwood City, California • Baltimore, Maryland • Columbia, Maryland + 3 more
Source: ClinicalTrials.gov public record
Updated May 16, 2025 · Synced Oct 1, 2026, 7:12 AM EDT
Completed No phase listed Observational

Comparison of a MAGNET Protocol Versus "off-on" Protocol for Patients With Implantable Cardioverter Defibrillators

NCT01599065
View directory record Official record
Conditions
Sudden Cardiac Death, Arrhythmia, Heart Failure
Interventions
Magnet or Off-On
Other
Lead sponsor
Midwest Heart Foundation
Other
Eligibility
19 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
3
States / cities
Downers Grove, Illinois • Elmhurst, Illinois • Naperville, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 21, 2013 · Synced Oct 1, 2026, 7:12 AM EDT
Completed Not applicable Interventional Results available

Circulation Improving Resuscitation Care (CIRC)

NCT00597207
View directory record Official record
Conditions
Cardiac Arrest, Cardiopulmonary Resuscitation
Interventions
AutoPulse, Manual
Device · Other
Lead sponsor
Zoll Medical Corporation
Industry
Eligibility
18 Years and older
Enrollment
4,231 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
3
States / cities
Tampa, Florida • Houston, Texas • Menasha, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 24, 2018 · Synced Oct 1, 2026, 7:12 AM EDT
Recruiting No phase listed Observational

HeartStart FRx Defibrillator Event Registry

NCT04250857
View directory record Official record
Conditions
Sudden Cardiac Arrest
Interventions
HeartStart FRX
Device
Lead sponsor
Heartstream US LLC
Industry
Eligibility
Not listed
Enrollment
1,400 participants
Timeline
2019 – 2030
U.S. locations
1
States / cities
Monroeville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 1, 2026, 7:12 AM EDT
Completed Not applicable Interventional

Sternal Wall Pressure in the Cath Lab

NCT01117883
View directory record Official record
Conditions
Perfusion Pressures, Central Venous Pressure, Cardiac Output, CPR, Cardiac Arrest
Interventions
Application of two different sternal weights
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
6 Months to 7 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 14, 2011 · Synced Oct 1, 2026, 7:12 AM EDT
Recruiting Not applicable Interventional

Mind-body Resilience Program for Cardiac Arrest Survivors and Their Caregivers: Recovering Together After Cardiac Arrest

NCT07143357
View directory record Official record
Conditions
Emotional Distress, Cardiac Arrest (CA), Anxiety, Depression, Caregivers, Survivorship, Resilience, Mindfulness
Interventions
Recovering Together after Cardiac Arrest 1, Recovering Together after Cardiac Arrest 2
Behavioral · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 23, 2025 · Synced Oct 1, 2026, 7:12 AM EDT
Withdrawn Early Phase 1 Interventional Accepts healthy volunteers

Rapid Reversal of CNS-Depressant Drug Effect Prior to Brain Death Determination

NCT03743805
View directory record Official record
Conditions
Brain Death, Anoxic Brain Injury, Cardiac Arrest, Sedative Intoxication, Narcotic Intoxication
Interventions
Flumazenil, Naloxone
Drug
Lead sponsor
Prisma Health-Midlands
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 31, 2024 · Synced Oct 1, 2026, 7:12 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Boston Circulatory Arrest Study: Antecedents and Correlates of Well-Being in Adults With Congenital Heart Disease

NCT03073122
View directory record Official record
Conditions
Transposition Great Arteries, Executive Dysfunction
Interventions
Brain MRI, neurocognitive and psychological testing
Diagnostic Test
Lead sponsor
Boston Children's Hospital
Other
Eligibility
24 Years to 33 Years
Enrollment
127 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 16, 2023 · Synced Oct 1, 2026, 7:12 AM EDT
Recruiting Phase 1 Interventional

A Phase 1, Dose Escalation Trial of RP-A601 in Subjects With PKP2 Variant-Mediated Arrhythmogenic Cardiomyopathy (PKP2-ACM)

NCT05885412
View directory record Official record
Conditions
PKP2 Arrhythmogenic Cardiomyopathy (PKP2-ACM)
Interventions
RP-A601
Genetic
Lead sponsor
Rocket Pharmaceuticals Inc.
Industry
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
3
States / cities
La Jolla, California • Durham, North Carolina • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Oct 1, 2026, 7:12 AM EDT
Terminated No phase listed Observational

RHAPSody: Diagnostic Utility of RUSH Following ROSC

NCT03409289
View directory record Official record
Conditions
Cardiac Arrest
Interventions
RUSH Exam
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 27, 2022 · Synced Oct 1, 2026, 7:12 AM EDT
Completed No phase listed Observational

Study of the Implantable Cardioverter Defibrillator (ICD) Intracardiac Electrograms

NCT00916435
View directory record Official record
Conditions
Congestive Heart Failure, Sudden Cardiac Death, Arrhythmia, Cardiomyopathies
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
630 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
2
States / cities
Baltimore, Maryland • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 21, 2015 · Synced Oct 1, 2026, 7:12 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Obstetric Life Support, a Curriculum to Effectively Resuscitate Pregnant Patients Experiencing Cardiac Arrest.

NCT05355519
View directory record Official record
Conditions
Cardiac Arrest, Pregnancy Related
Interventions
Electronic curriculum and instructor-led course, then placebo, Placebo, then electronic curriculum and instructor-led course
Other
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated May 2, 2022 · Synced Oct 1, 2026, 7:12 AM EDT
Terminated Phase 2Phase 3 Interventional

Assessing CPR Quality During In-Hospital Cardiac Arrest

NCT00228293
View directory record Official record
Conditions
Cardiac Arrest
Interventions
investigational monitor/defibrillator with CPR feedback
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 23, 2013 · Synced Oct 1, 2026, 7:12 AM EDT