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ClinicalTrials.gov public records Last synced Oct 30, 2026, 2:11 AM EDT

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Showing 1369–1392 of 2,293 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Cardiac Ischemia Clear all
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Molecular and Morphologic Characterization of Circulating Endothelial Cells

NCT01005485
View directory record Official record
Conditions
Acute Myocardial Infarction
Interventions
Not listed
Lead sponsor
Scripps Translational Science Institute
Other
Eligibility
18 Years to 80 Years
Enrollment
664 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2025
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jan 17, 2025 · Synced Oct 30, 2026, 2:11 AM EDT
Completed Not applicable Interventional

Aortic Valve and Root Measurements Under Real-Time 3-Dimensional Visualization During Angiography

NCT02073617
View directory record Official record
Conditions
Coronary Artery Disease, Aortic Stenosis
Interventions
Real-time 3-dimensional DynaCT
Radiation
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 18, 2017 · Synced Oct 30, 2026, 2:11 AM EDT
Completed No phase listed Observational

Myeloperoxidase and Multi-Markers In the Diagnosis of Diagnoses of Acute Coronary Syndrome (MIDAS) - Sample Procurement

NCT00415948
View directory record Official record
Conditions
Acute Coronary Syndrome (ACS)
Interventions
Biomarkers
Device
Lead sponsor
Abbott RDx Cardiometabolic
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
18
States / cities
Sacramento, California • New Haven, Connecticut • Baltimore, Maryland + 13 more
Source: ClinicalTrials.gov public record
Updated Dec 18, 2009 · Synced Oct 30, 2026, 2:11 AM EDT
Completed No phase listed Observational

Intracoronary Imaging With NIRS-IVUS to Characterize Arterial Plaques

NCT01694368
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Not listed
Lead sponsor
Corewell Health West
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2021
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Oct 30, 2026, 2:11 AM EDT
Completed Phase 4 Interventional Results available

Vorapaxar as an Add-On Antiplatelet Therapy in Patients With and Without Diabetes Mellitus

NCT02548650
View directory record Official record
Conditions
Myocardial Infarction, Diabetes Mellitus, Peripheral Arterial Disease
Interventions
Vorapaxar, Clopidogrel, Aspirin
Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 12, 2020 · Synced Oct 30, 2026, 2:11 AM EDT
Completed Phase 4 Interventional

QWISE - Study of Quinapril in Women With Chest Pain, Coronary Flow Reserve Limitations and Evidence of Myocardial Ischemia

NCT00150826
View directory record Official record
Conditions
Ischemic Heart Disease
Interventions
Quinapril, Placebo
Drug
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 75 Years · Female only
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2004
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 13, 2012 · Synced Oct 30, 2026, 2:11 AM EDT
Recruiting Phase 1 Interventional

Study Targeting Myocardial Perfusion and Symptom Relief in Women With SGLT2 Inhibitors (STRONG)

NCT06600178
View directory record Official record
Conditions
Angina Patients With Non-obstructive Coronary Artery Disease, Coronary Microvascular Disease, Coronary Microvascular Dysfunction (CMD)
Interventions
Brenzavvy (bexagliflozin), 20 mg Oral Tablet, Placebo
Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older · Female only
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 30, 2026, 2:11 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Alirocumab and Reverse Cholesterol Transport

NCT03014830
View directory record Official record
Conditions
Atherosclerosis, Coronary Heart Disease
Interventions
Alirocumab, Placebos
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 80 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 7, 2018 · Synced Oct 30, 2026, 2:11 AM EDT
Recruiting No phase listed Observational

Abbott Vascular Medical Device Registry

NCT04573660
View directory record Official record
Conditions
Acute Myocardial Infarction, Restenoses, Coronary, Coronary Artery Lesions, Venous Embolism, Arterial Embolism
Interventions
Coronary and peripheral stents, Pacing catheters, Vascular plugs, Measurement and imaging (FFR and OCT), Peripheral dilatation catheters, Coronary dilatation catheters, Coronary and peripheral guidewires, Vessel closure/compression devices, Vascular access introducers
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
3,784 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2031
U.S. locations
7
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Los Angeles, California + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 30, 2026, 2:11 AM EDT
Terminated Not applicable Interventional Results available

Safety and Accuracy of Regadenoson-Atropine Stress Echocardiography in CAD

NCT00894179
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
regadenoson and atropine
Diagnostic Test
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 85 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 30, 2026, 2:11 AM EDT
Completed Not applicable Interventional

Low-Carbohydrate and Plant-Based Dietary Effects on Vascular Health

NCT05414851
View directory record Official record
Conditions
Heart Disease, Ischemic, Hyperlipidemias, Hypertension
Interventions
Whole-Food, Plant-Based Diet and Low-Carbohydrate Diet
Other
Lead sponsor
University of Rochester
Other
Eligibility
50 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Webster, New York
Source: ClinicalTrials.gov public record
Updated Jul 16, 2024 · Synced Oct 30, 2026, 2:11 AM EDT
Completed Phase 3 Interventional

The Role of Angiotensin Type I Receptor in the Regulation of Human Coronary Vascular Function

NCT00001629
View directory record Official record
Conditions
Atherosclerosis, Heart Failure, Congestive, Hypertension, Myocardial Infarction
Interventions
Angiotensin II type 1 receptor antagonists
Drug
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
Not listed
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2000
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 30, 2026, 2:11 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Study of Circulating Monocytes in Patients With Ischemic Vascular Disease

NCT04321512
View directory record Official record
Conditions
Myocardial Infarction, Stroke, Ischemic, Ischemia
Interventions
There is no intervention given to the subjects
Other
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2027
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 30, 2026, 2:11 AM EDT
Not listed Not applicable Interventional

Mobile Health Strategies for Veterans

NCT03022669
View directory record Official record
Conditions
Coronary Heart Disease
Interventions
Text Message, Mobile Application, Website
Behavioral · Other
Lead sponsor
San Francisco Veterans Affairs Medical Center
Federal
Eligibility
21 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
5
States / cities
Concord, California • Palo Alto, California • San Francisco, California + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 29, 2021 · Synced Oct 30, 2026, 2:11 AM EDT
Terminated Not applicable Interventional Results available

Novel Adenosine-independent Index of Coronary Artery Stenosis Severity Resting Flow Reserve

NCT03461705
View directory record Official record
Conditions
Coronary; Ischemic
Interventions
Volcano Verrata Pressure Wire, St. Jude Medical (SJM) Aeris Pressure Wire System
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 7, 2020 · Synced Oct 30, 2026, 2:11 AM EDT
Completed Phase 3 Interventional Results available

Lipoprotein-associated Phospholipase A2 (Lp-PLA2) Progenitor Cells and Coronary Atherosclerosis in Humans

NCT01067339
View directory record Official record
Conditions
Endothelial Dysfunction
Interventions
darapladib, placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 18, 2017 · Synced Oct 30, 2026, 2:11 AM EDT
Completed No phase listed Observational

Study of Hepatitis Eradication Receiving Protease Inhibitor Administration

NCT03886077
View directory record Official record
Conditions
Coronary Artery Disease, Morality
Interventions
glecaprevir/pibrentasivir
Drug
Lead sponsor
Sentara Norfolk General Hospital
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 30, 2026, 2:11 AM EDT
Completed Phase 3 Interventional Results available

A Study to Assess Regadenoson Administration Following an Inadequate Exercise Stress Test as Compared to Regadenoson Alone for Myocardial Perfusion Imaging (MPI) Using Single Photon Emission Computed Tomography (SPECT)

NCT01618669
View directory record Official record
Conditions
Coronary Artery Disease (CAD)
Interventions
Regadenoson, Single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI)
Drug · Procedure
Lead sponsor
Astellas Pharma Global Development, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1,147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
60
States / cities
Mobile, Alabama • Fremont, California • Long Beach, California + 52 more
Source: ClinicalTrials.gov public record
Updated Feb 8, 2016 · Synced Oct 30, 2026, 2:11 AM EDT
Terminated Not applicable Interventional

IDE-ALERTS Continued Access Study

NCT04316481
View directory record Official record
Conditions
Acute Coronary Syndrome
Interventions
AngelMed Guardian System
Device
Lead sponsor
Angel Medical Systems
Industry
Eligibility
21 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2022 · Synced Oct 30, 2026, 2:11 AM EDT
Withdrawn Early Phase 1 Interventional Accepts healthy volunteers

Rapid Reversal of CNS-Depressant Drug Effect Prior to Brain Death Determination

NCT03743805
View directory record Official record
Conditions
Brain Death, Anoxic Brain Injury, Cardiac Arrest, Sedative Intoxication, Narcotic Intoxication
Interventions
Flumazenil, Naloxone
Drug
Lead sponsor
Prisma Health-Midlands
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 31, 2024 · Synced Oct 30, 2026, 2:11 AM EDT
Terminated Phase 3 Interventional Results available

Aspirin in Patients With Myocardial Infarction and Thrombocytopenia

NCT00501345
View directory record Official record
Conditions
Thrombocytopenia, Myocardial Infarction
Interventions
Aspirin
Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Not listed
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 1, 2012 · Synced Oct 30, 2026, 2:11 AM EDT
Not listed No phase listed Observational

GLOBAL Clinical Study

NCT01738828
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Not listed
Lead sponsor
Global Genomics Group, LLC
Industry
Eligibility
18 Years to 90 Years
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
29
States / cities
Huntsville, Alabama • Tucson, Arizona • Roseville, California + 22 more
Source: ClinicalTrials.gov public record
Updated Feb 9, 2016 · Synced Oct 30, 2026, 2:11 AM EDT
Completed No phase listed Observational Results available

PCP Use of a Gene Expression Test (Corus CAD or ASGES) in Coronary Artery Disease Diagnosis

NCT01594411
View directory record Official record
Conditions
Chest Pain, Cardiovascular Diseases, Angina Pectoris, Coronary Artery Disease, CAD, CVD, CHD, Coronary Heart Disease
Interventions
Corus CAD
Diagnostic Test
Lead sponsor
CardioDx
Industry
Eligibility
21 Years and older
Enrollment
251 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
4
States / cities
Suwanee, Georgia • Baton Rouge, Louisiana • Charlotte, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 31, 2019 · Synced Oct 30, 2026, 2:11 AM EDT
Completed Phase 4 Interventional

This Study Uses Ultrasound to Determine Whether Atorvastatin or Pravastatin Effects the Progression of Coronary Plaque.

NCT00380939
View directory record Official record
Conditions
Coronary Arteriosclerosis
Interventions
Atorvastatin, Pravastatin
Drug
Lead sponsor
Pfizer
Industry
Eligibility
30 Years to 75 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2000
U.S. locations
36
States / cities
Little Rock, Arkansas • Los Angeles, California • San Diego, California + 30 more
Source: ClinicalTrials.gov public record
Updated Dec 4, 2006 · Synced Oct 30, 2026, 2:11 AM EDT