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Showing 1–24 of 109 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cardiac Output Clear all
Completed No phase listed Observational

Peripheral Venous Oxygen Saturation and Biomarkers to Estimate Cardiac Output and Filling Pressures in Heart Failure

NCT00595738
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Standard of care therapy for severe decompensated heart failure
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 19, 2011 · Synced Jun 7, 2026, 6:21 AM EDT
Completed No phase listed Observational

Changes in Hemodynamic Values With Posture

NCT02557009
View directory record Official record
Conditions
Blood Pressure
Interventions
Not listed
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 24, 2017 · Synced Jun 7, 2026, 6:21 AM EDT
Completed No phase listed Observational

Comparing Cardiac Output Measurements in Critically Ill Children Using USCOM and Transthoracic ECHO

NCT01460329
View directory record Official record
Conditions
Critical Illness, Pediatrics
Interventions
Ultrasonic Cardiac Output Monitor (USCOM).
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
1 Day to 17 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 5, 2013 · Synced Jun 7, 2026, 6:21 AM EDT
Withdrawn Not applicable Interventional

Phenylephrine Dose and Mode of Administration for Spinal Anesthesia Induced Hypotension

NCT02101047
View directory record Official record
Conditions
Complications; Cesarean Section, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Interventions
Phenylephrine
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 7, 2017 · Synced Jun 7, 2026, 6:21 AM EDT
Withdrawn No phase listed Observational

Noninvasive Cardiac Output Measurements in Patients With Pulmonary Hypertension Undergoing Exercise Testing

NCT01275703
View directory record Official record
Conditions
Pulmonary Hypertension
Interventions
Not listed
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 22, 2015 · Synced Jun 7, 2026, 6:21 AM EDT
Completed Phase 4 Interventional Results available

Evaluation of Arterial Pressure Based Cardiac Output for Goal-Directed Perioperative Therapy

NCT00526331
View directory record Official record
Conditions
Esophageal Diseases, Gastrointestinal Diseases, Disorder of the Genitourinary System, Gynecologic Diseases, Kidney Diseases, Liver Diseases, Pancreatic Diseases, Prostate Cancer, Spinal Disease
Interventions
Vigileo Monitor, FloTrac Sensor
Device
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 15, 2012 · Synced Jun 7, 2026, 6:21 AM EDT
Recruiting No phase listed Observational

The HIgh-fidelity Hydraulic couPling Upper-arm Cuff Assessment of Limits, Safety, and Effectiveness (HIPULSE) Trial (Cardiac Output Study)

NCT06895603
View directory record Official record
Conditions
ICU, Pulmonary Artery Catheter (PAC), Swan-Ganz Catheter
Interventions
Philips Advanced Monitoring Cuff (AMC)
Device
Lead sponsor
Philips Clinical & Medical Affairs Global
Industry
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Jun 7, 2026, 6:21 AM EDT
Withdrawn Not applicable Interventional

The Feasibility and Accuracy of Exhaled CO2 to Measure Cardiac Output in Ventilated Patients Without Tracheal Intubation

NCT00783679
View directory record Official record
Conditions
Cardiac Physiology, Cardiac Output
Interventions
NICO device
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2012 · Synced Jun 7, 2026, 6:21 AM EDT
Completed No phase listed Observational

Prognostic Markers of Inflammation in Infants Undergoing Cardiopulmonary Bypass

NCT03143348
View directory record Official record
Conditions
Congenital Heart Defect, Cardiopulmonary Bypass, Inflammatory Response, Low Cardiac Output Syndrome, Inflammation
Interventions
Single blood draw, Multiple blood draws
Procedure
Lead sponsor
University of Oklahoma
Other
Eligibility
Up to 6 Months
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 29, 2019 · Synced Jun 7, 2026, 6:21 AM EDT
Completed No phase listed Observational Results available

Noninvasive Measurement of CO Using Impedance Cardiography in Patients With CHD

NCT02326649
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
Physioflow
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
Not listed
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 11, 2017 · Synced Jun 7, 2026, 6:21 AM EDT
Recruiting No phase listed Observational

Passive Leg Raise and Mini-fluid Challenge Effect on Various Cardiac Output Surrogates for Fluid Responsiveness

NCT06390423
View directory record Official record
Conditions
Fluid Responsiveness
Interventions
Passive leg raise, SVI via bioreactance, Echo based VTI
Diagnostic Test
Lead sponsor
CentraCare
Other
Eligibility
30 Years to 90 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Saint Cloud, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 21, 2024 · Synced Jun 7, 2026, 6:21 AM EDT
Not yet recruiting No phase listed Observational Accepts healthy volunteers

Finger Plethysmography to Predict Fluid Responsiveness in Healthy Pregnancy and Severe Preeclampsia

NCT07430254
View directory record Official record
Conditions
Pre-Eclampsia, Severe, Pregnancy
Interventions
Noninvasive finger plethysmographic cardiac output monitoring, Standard transthoracic echocardiographic assessment
Diagnostic Test
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Jun 7, 2026, 6:21 AM EDT
Completed No phase listed Observational

Comparison of Cardiac Output With LiDCO Rapid and TEE Against Thermodilution Technique in Cardiac Surgery

NCT02511457
View directory record Official record
Conditions
Low Cardiac Output
Interventions
Not listed
Lead sponsor
University of Iowa
Other
Eligibility
30 Years to 90 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Oct 24, 2016 · Synced Jun 7, 2026, 6:21 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Comparison Studies Comparing Hemodynamic Parameters Provided by the Caretaker Against Respective Gold Standard References

NCT05035719
View directory record Official record
Conditions
Cardiac Output, Low
Interventions
non-invasive cardiac output monitor
Device
Lead sponsor
CareTaker Medical LLC
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 4, 2021 · Synced Jun 7, 2026, 6:21 AM EDT
Completed No phase listed Observational

Cardiac Output Monitoring in Critically Ill Patient Undergoing Intubation

NCT03525743
View directory record Official record
Conditions
Hypotension
Interventions
NICOM (Non invasive cardiac output monitor)
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
2
States / cities
Rochester, Minnesota • New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 31, 2022 · Synced Jun 7, 2026, 6:21 AM EDT
Terminated Not applicable Interventional Results available

An Open Label Trial to Decrease Signs and Symptoms of Orthostatic Hypotension Using Midodrine or Intravenous Fluid Bolus in Patients Following Total Hip Arthroplasty

NCT02154243
View directory record Official record
Conditions
Orthostatic Hypotension
Interventions
Midodrine, Intravenous fluid bolus
Drug · Other
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 90 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 30, 2017 · Synced Jun 7, 2026, 6:21 AM EDT
Completed No phase listed Observational

A Prospective Study of a New Non-Invasive Cardiac Output Monitor in Children Undergoing General Anesthesia

NCT01499615
View directory record Official record
Conditions
Children Receiving General Anesthesia
Interventions
cardiac monitor
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
1 Hour to 18 Years
Enrollment
402 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 8, 2015 · Synced Jun 7, 2026, 6:21 AM EDT
Completed Phase 2 Interventional Results available

Corticosteroids in Postoperative Critically Ill Neonates With Low Cardiac Output Syndrome With Congenital Heart Disease

NCT00590018
View directory record Official record
Conditions
Cardiac Output, Low
Interventions
Hydrocortisone, Placebo
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
Up to 1 Month
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 25, 2016 · Synced Jun 7, 2026, 6:21 AM EDT
Completed Not applicable Interventional Results available

Minimally Invasive Cardiac Output Monitoring Device

NCT01675063
View directory record Official record
Conditions
Cardiac Event
Interventions
Retia Non-Invasive Sensors
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 7, 2017 · Synced Jun 7, 2026, 6:21 AM EDT
Completed Not applicable Interventional

Noninvasive Cardiac Output Monitoring in Pulmonary Hypertension

NCT02951104
View directory record Official record
Conditions
Pulmonary Hypertension
Interventions
Ultrasonic Cardiac Output Monitor (USCOM) system
Device
Lead sponsor
Santa Barbara Cottage Hospital
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Mar 9, 2022 · Synced Jun 7, 2026, 6:21 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Descriptive Study of Cardiac Output During Rehydration With Recombinant Human Hyaluronidase in Pediatrics

NCT01139294
View directory record Official record
Conditions
Dehydration, Cardiac Output, Pediatrics
Interventions
Hylenex
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
2 Months to 3 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 31, 2018 · Synced Jun 7, 2026, 6:21 AM EDT
Completed No phase listed Observational

ClearSight Validation in Pediatrics

NCT03701646
View directory record Official record
Conditions
Shock, Hypotension and Shock
Interventions
Measurement by Clearsight device
Device
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
0 Years to 17 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Jun 22, 2023 · Synced Jun 7, 2026, 6:21 AM EDT
Completed Not applicable Interventional

Hemodynamic Optimization By Non-Invasive Determination Of Cardiac Output In Critically Ill Patients

NCT01309724
View directory record Official record
Conditions
Hypotension
Interventions
USCOM-guided fluid administration
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 6, 2011 · Synced Jun 7, 2026, 6:21 AM EDT
Completed No phase listed Observational

Validation of Minimally Invasive Ultrasound Indicator Dilution Technique in Critically Ill Children

NCT00852254
View directory record Official record
Conditions
Cardiac Output
Interventions
Not listed
Lead sponsor
Transonic Systems Inc.
Industry
Eligibility
Up to 18 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 26, 2016 · Synced Jun 7, 2026, 6:21 AM EDT