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ClinicalTrials.gov public records Last synced Oct 22, 2026, 8:41 AM EDT

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Showing 49–72 of 113 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Cardiac Output Clear all
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

COR-INSIGHT: Optimizing Cardiovascular and Cardiopulmonary Outcomes with AI-Driven Multiplexed Indications Using COR ECG Wearable

NCT06763549
View directory record Official record
Conditions
Cardiopulmonary Failure, Myocardial Infarction (MI), Heart Decompensation, Heart Failure, HFrEF - Heart Failure with Reduced Ejection Fraction, HFpEF - Heart Failure with Preserved Ejection Fraction, Syncopation, Syncope, Ischemic Cardiovascular Disease, STEMI, STEMI (ST Elevation MI), Atrial Fibrillation (AF), Atrial Enlargement, LVF, Conduction Defect, Conduction Abnormalities, Heart Block, Valvular Diseases, Cardiac Output, Low, Stroke Volume, Stroke Volume Variation, Hyperkalemia, Hypercalcemia, Hypocalcemia, LV Dysfunction, QT Prolongation, Sudden Cardiac Death Due to Cardiac Arrhythmia, Ventricular Arrhythmia, Pacing, Pacing Induced Dyssynchrony, Silent Ischemia, Pericarditis, Sleep Related Breathing Disorder, RSA, Apnea, Obstructive, Cardiac Output Measurement, Respiratory Impedance, CRT And/or ICD, Infarction, Cardiomyopathies, Primary, Hypertrophy
Interventions
SUBPROTOCOL A, SUBPROTOCOL B, SUBPROTOCOL C, SUBPROTOCOL D, SUBPROTOCOL E, SUBPROTOCOL F, SUBPROTOCOL G, SUBPROTOCOL H
Device
Lead sponsor
Peerbridge Health, Inc
Industry
Eligibility
18 Years and older
Enrollment
15,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Melbourne, Florida
Source: ClinicalTrials.gov public record
Updated Jan 8, 2025 · Synced Oct 22, 2026, 8:41 AM EDT
Completed No phase listed Observational

Peripheral Venous Oxygen Saturation and Biomarkers to Estimate Cardiac Output and Filling Pressures in Heart Failure

NCT00595738
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Standard of care therapy for severe decompensated heart failure
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 20, 2011 · Synced Oct 22, 2026, 8:41 AM EDT
Terminated No phase listed Observational

Determination of the Accuracy of a Non-Invasive Continuous Blood Pressure Device

NCT01311128
View directory record Official record
Conditions
Critically Ill
Interventions
T-line hemodynamic monitoring device (placement and use)
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 22, 2026, 8:41 AM EDT
Completed No phase listed Observational

Cardiac Output Pulmonary Arterial Catheter Compared to FloWave™ 1000

NCT00665301
View directory record Official record
Conditions
Congestive Heart Failure, Ischemic Cardiomyopathy, Mitral Valve Prolapse, Mitral Regurgitation, Aortic Valve Disease, Tricuspid Regurgitation
Interventions
Not listed
Lead sponsor
Woolsthorpe Technologies, LLC
Industry
Eligibility
18 Years to 95 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
3
States / cities
Nashville, Tennessee • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 8, 2008 · Synced Oct 22, 2026, 8:41 AM EDT
Recruiting Early Phase 1 Interventional

Cardiac Power Output in Cardiogenic Shock Patients

NCT05700617
View directory record Official record
Conditions
Heart Failure, Cardiogenic Shock
Interventions
1:1 Randomization to receive milrinone
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 22, 2026, 8:41 AM EDT
Completed No phase listed Observational Results available

Noninvasive Measurement of CO Using Impedance Cardiography in Patients With CHD

NCT02326649
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
Physioflow
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
Not listed
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 12, 2017 · Synced Oct 22, 2026, 8:41 AM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Cardiac Output Changes With Uterine Displacement

NCT02283931
View directory record Official record
Conditions
Obstetric Anesthesia, Cardiac Monitoring
Interventions
TTE / NICOM
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 22, 2026, 8:41 AM EDT
Completed Not applicable Interventional

Optimizing Left Ventricular Lead To Improve Cardiac Output

NCT01399801
View directory record Official record
Conditions
Ischemic Congestive Cardiomyopathy, Dilated Cardiomyopathy, Congestive Heart Failure
Interventions
Doppler flow measurement, standard implantation of the LV lead
Procedure
Lead sponsor
Ann Marie Chikowski
Other
Eligibility
Not listed
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Wynnewood, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 30, 2022 · Synced Oct 22, 2026, 8:41 AM EDT
Completed Not applicable Interventional Results available

Minimally Invasive Cardiac Output Monitoring Device

NCT01675063
View directory record Official record
Conditions
Cardiac Event
Interventions
Retia Non-Invasive Sensors
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 8, 2017 · Synced Oct 22, 2026, 8:41 AM EDT
Completed No phase listed Observational Results available

Pediatric Cardiac Output Monitoring Observational Study

NCT04465370
View directory record Official record
Conditions
Pediatric ALL
Interventions
Hemosphere Advanced Monitoring System, ClearSight 1.5, Swan-Ganz Catheter, Flotrac, Foresight
Device
Lead sponsor
Edwards Lifesciences
Industry
Eligibility
12 Years to 18 Years
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
3
States / cities
Gainesville, Florida • Philadelphia, Pennsylvania • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 18, 2024 · Synced Oct 22, 2026, 8:41 AM EDT
Completed Not applicable Interventional Results available

Understanding Outcomes With the EMBLEM™ S-ICD in Primary Prevention Patients With Low Ejection Fraction

NCT02433379
View directory record Official record
Conditions
Ventricular Fibrillation, Ventricular Tachycardia, Low Cardiac Output
Interventions
EMBLEM S-ICD System
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
21 Years and older
Enrollment
1,173 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
69
States / cities
Birmingham, Alabama • Huntsville, Alabama • Gilbert, Arizona + 62 more
Source: ClinicalTrials.gov public record
Updated Mar 24, 2025 · Synced Oct 22, 2026, 8:41 AM EDT
Completed No phase listed Observational

Validation of Minimally Invasive Ultrasound Indicator Dilution Technique in Critically Ill Children

NCT00852254
View directory record Official record
Conditions
Cardiac Output
Interventions
Not listed
Lead sponsor
Transonic Systems Inc.
Industry
Eligibility
Up to 18 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 27, 2016 · Synced Oct 22, 2026, 8:41 AM EDT
Not yet recruiting No phase listed Observational

UltraTrac Clinical Pilot Study

NCT07864714
View directory record Official record
Conditions
Hemodynamic Monitoring
Interventions
Noninvasive Hemodynamic Monitoring System
Device
Lead sponsor
AcQumen Medical, Inc.
Industry
Eligibility
0 Years to 21 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 22, 2026, 8:41 AM EDT
Completed No phase listed Observational

Plethysmography Variability Index as an Indicator of Adequacy of Preload

NCT01285622
View directory record Official record
Conditions
Gynecological Surgery
Interventions
Not listed
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 5, 2021 · Synced Oct 22, 2026, 8:41 AM EDT
Active, not recruiting Not applicable Interventional

The Smart Pump Study

NCT04465201
View directory record Official record
Conditions
Cardiac Output
Interventions
Impella CP with Smart Assist (Circulatory Support System)
Device
Lead sponsor
Abiomed Inc.
Industry
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
6
States / cities
New Orleans, Louisiana • Boston, Massachusetts • Detroit, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 24, 2022 · Synced Oct 22, 2026, 8:41 AM EDT
Completed No phase listed Observational

Changes in Hemodynamic Values With Posture

NCT02557009
View directory record Official record
Conditions
Blood Pressure
Interventions
Not listed
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 25, 2017 · Synced Oct 22, 2026, 8:41 AM EDT
Not yet recruiting Not applicable Interventional

UltraTrac for Cardiac Output Monitoring in Congenital Heart Disease

NCT07866573
View directory record Official record
Conditions
Congenital Heart Disease, Cardiac Output, Hemodynamic Monitoring, Pediatric Heart Disease
Interventions
UltraTrac
Device
Lead sponsor
University of Minnesota
Other
Eligibility
0 Years to 80 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 22, 2026, 8:41 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Caretaker Hemodynamic Parameters Validation

NCT04685733
View directory record Official record
Conditions
Blood Pressure, Cardiac Output, Left Ventricular Ejection Time, Heart Rate Variability
Interventions
Non-invasive hemodynamic measurements
Device
Lead sponsor
CareTaker Medical LLC
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 28, 2020 · Synced Oct 22, 2026, 8:41 AM EDT
Completed Not applicable Interventional

Esophageal Echo Assessment of LV Function During Acute Normovolemic Hemodilution Using Crystalloid or Hypertonic Saline

NCT00683007
View directory record Official record
Conditions
Acute Hypovolemia
Interventions
Volume resuscitation (Crystalloid), Volume resuscitation (Hypertonic Saline Solution)
Other
Lead sponsor
University of California, Davis
Other
Eligibility
17 Years to 70 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated May 30, 2017 · Synced Oct 22, 2026, 8:41 AM EDT
Completed No phase listed Observational

A Prospective Study of a New Non-Invasive Cardiac Output Monitor in Children Undergoing General Anesthesia

NCT01499615
View directory record Official record
Conditions
Children Receiving General Anesthesia
Interventions
cardiac monitor
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
1 Hour to 18 Years
Enrollment
402 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 9, 2015 · Synced Oct 22, 2026, 8:41 AM EDT
Not listed Phase 4 Interventional

Early Caffeine in Preterm Neonates

NCT03086473
View directory record Official record
Conditions
BPD - Bronchopulmonary Dysplasia, Apnea of Prematurity, Hemodynamic Instability, Intubation
Interventions
Caffeine Citrate, Placebo (Normal Saline)
Drug
Lead sponsor
Jennifer Shepherd
Other
Eligibility
Up to 1 Day
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 3, 2021 · Synced Oct 22, 2026, 8:41 AM EDT
Withdrawn Not applicable Interventional

The Feasibility and Accuracy of Exhaled CO2 to Measure Cardiac Output in Ventilated Patients Without Tracheal Intubation

NCT00783679
View directory record Official record
Conditions
Cardiac Physiology, Cardiac Output
Interventions
NICO device
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 25, 2012 · Synced Oct 22, 2026, 8:41 AM EDT
Not listed No phase listed Observational

Cardiac Output Measurement by TEE

NCT03349970
View directory record Official record
Conditions
Cardiac Disease
Interventions
Not listed
Lead sponsor
University Health Network, Toronto
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 14, 2019 · Synced Oct 22, 2026, 8:41 AM EDT
Completed No phase listed Observational

ClearSight Validation in Pediatrics

NCT03701646
View directory record Official record
Conditions
Shock, Hypotension and Shock
Interventions
Measurement by Clearsight device
Device
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
0 Years to 17 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Jun 23, 2023 · Synced Oct 22, 2026, 8:41 AM EDT