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ClinicalTrials.gov public records Last synced Oct 18, 2026, 6:21 AM EDT

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Showing 1–24 of 146 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Cardiac Resynchronization Therapy Clear all
Withdrawn Not applicable Interventional

Effects of CRT Optimization as Assessed by Cardiac MR

NCT04763460
View directory record Official record
Conditions
Heart Failure, Systolic
Interventions
Programming of CRT device settings
Device
Lead sponsor
Minneapolis Heart Institute Foundation
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Minneapolis, Minnesota • Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Oct 18, 2026, 6:21 AM EDT
Completed Not applicable Interventional

Does Echocardiographically Guided Ventriculo-Ventricular Optimization Yield a Sustained Improvement in Echocardiographic Parameters in Cardiac Resynchronization Therapy Patients? (DEVISE CRT)

NCT00737490
View directory record Official record
Conditions
Cardiomyopathy, Heart Failure
Interventions
"Sequential Arm" (Promote , model # 2207-36 or Atlas HF , model # V-343), "Simultaneous Arm" (Promote , model # 2207-36 or Atlas HF , model # V-343)
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 1, 2014 · Synced Oct 18, 2026, 6:21 AM EDT
Completed Not applicable Interventional Results available

Attain Model 4196 Left Ventricular (LV) Lead

NCT00271544
View directory record Official record
Conditions
Heart Failure
Interventions
Pacing Lead
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
19
States / cities
Anchorage, Alaska • Phoenix, Arizona • Long Beach, California + 16 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2009 · Synced Oct 18, 2026, 6:21 AM EDT
Withdrawn Not applicable Interventional

Evaluation of Left Bundle Branch Area Pacing As A Rescue Strategy for Cardiac Resynchronization Therapy Non-Response

NCT05884411
View directory record Official record
Conditions
Systolic Heart Failure, Heart Failure With Reduced Ejection Fraction, CRT Non-Response, Left Bundle Branch Area Pacing
Interventions
Left bundle branch area pacing, Cardiac MRI
Device · Diagnostic Test
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 11, 2025 · Synced Oct 18, 2026, 6:21 AM EDT
Completed Not applicable Interventional Results available

Cardiac Resynchronization in the Elderly

NCT03031847
View directory record Official record
Conditions
Heart Failure
Interventions
Cardiac Resynchronization Therapy Pacemaker, Cardiac Resynchronization Therapy Defibrillator
Device
Lead sponsor
Samir Saba
Other
Eligibility
75 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
6
States / cities
Durham, North Carolina • Columbus, Ohio • Erie, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 7, 2023 · Synced Oct 18, 2026, 6:21 AM EDT
Not listed Not applicable Interventional

Cardiac Magnetic Resonance Imaging After Cardiac Resynchronization Therapy

NCT03183011
View directory record Official record
Conditions
Heart Failure, Systolic
Interventions
MRI
Other
Lead sponsor
Kenneth Bilchick, MD
Other
Eligibility
25 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 12, 2017 · Synced Oct 18, 2026, 6:21 AM EDT
Completed Not applicable Interventional

Optimizing Left Ventricular Lead To Improve Cardiac Output

NCT01399801
View directory record Official record
Conditions
Ischemic Congestive Cardiomyopathy, Dilated Cardiomyopathy, Congestive Heart Failure
Interventions
Doppler flow measurement, standard implantation of the LV lead
Procedure
Lead sponsor
Ann Marie Chikowski
Other
Eligibility
Not listed
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Wynnewood, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 30, 2022 · Synced Oct 18, 2026, 6:21 AM EDT
Completed Phase 2 Interventional

Evaluation of a Diagnostic Feature in a Cardiac Resynchronization Therapy (CRT) Device

NCT00957541
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Paradym CRT + Physiological Diagnosis (PhD)
Device
Lead sponsor
ELA Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
520 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Mesa, Arizona
Source: ClinicalTrials.gov public record
Updated May 15, 2014 · Synced Oct 18, 2026, 6:21 AM EDT
Terminated Not applicable Interventional Results available

BOOST - Benefit of Frequent Optimization After Cardiac Resynchronization Therapy Device Replacement

NCT00929474
View directory record Official record
Conditions
Heart Failure
Interventions
QuickOpt - SJM CRT (Group 1), Control - SJM CRT (Group 2)
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
2
States / cities
Aurora, Colorado • Hattiesburg, Mississippi
Source: ClinicalTrials.gov public record
Updated Feb 4, 2019 · Synced Oct 18, 2026, 6:21 AM EDT
Completed No phase listed Observational Results available

QuickFlex Micro Left Ventricular Lead Post Approval Study

NCT01179477
View directory record Official record
Conditions
Heart Failure
Interventions
Implantation of a QuickFlex® μ Model 1258T LV Lead
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
1,930 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
77
States / cities
Birmingham, Alabama • Huntsville, Alabama • Anchorage, Alaska + 67 more
Source: ClinicalTrials.gov public record
Updated Aug 12, 2019 · Synced Oct 18, 2026, 6:21 AM EDT
Completed No phase listed Observational

Evaluation of Multisensor Data in Heart Failure Patients With Implanted Devices

NCT01128166
View directory record Official record
Conditions
Heart Failure
Interventions
COGNIS CRT-D
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
975 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
81
States / cities
Anchorage, Alaska • Gilbert, Arizona • Little Rock, Arizona + 69 more
Source: ClinicalTrials.gov public record
Updated Oct 21, 2015 · Synced Oct 18, 2026, 6:21 AM EDT
Completed No phase listed Observational Results available

Strategic MAnagement to Optimize Response To Cardiac Resynchronization Therapy Registry

NCT03075215
View directory record Official record
Conditions
Heart Failure
Interventions
Device Programming of the Boston Scientific Cardiac Resynchronization Therapy Defibrillator (CRT-D)
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
2,044 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
29
States / cities
Anchorage, Alaska • Mesa, Arizona • Jonesboro, Arkansas + 26 more
Source: ClinicalTrials.gov public record
Updated Oct 25, 2023 · Synced Oct 18, 2026, 6:21 AM EDT
Terminated Not applicable Interventional Results available

ECG for Programming in CRT

NCT03936608
View directory record Official record
Conditions
Systolic Heart Failure, Cardiac Resynchronization Therapy, Electrocardiography
Interventions
Programming individualized RV-LV pacing offset to optimize ECG, Nominally programming CRT device without RV-LV offset
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 100 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 3, 2020 · Synced Oct 18, 2026, 6:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Strategic Management to Optimize Response To Cardiac Resynchronization Therapy

NCT03089281
View directory record Official record
Conditions
Heart Failure
Interventions
CRT-D
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
699 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
41
States / cities
Birmingham, Alabama • Huntsville, Alabama • Tucson, Arizona + 37 more
Source: ClinicalTrials.gov public record
Updated Apr 5, 2022 · Synced Oct 18, 2026, 6:21 AM EDT
Completed Not applicable Interventional

Stimulus Intensity in Left Ventricular Leads

NCT01060449
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
LV stimulus intensity
Other
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 17, 2013 · Synced Oct 18, 2026, 6:21 AM EDT
Completed Not applicable Interventional

Attain StarFix™ Model 4195 Left Ventricular Lead

NCT00269230
View directory record Official record
Conditions
Heart Failure
Interventions
Pacing Lead
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
441 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
20
States / cities
Long Beach, California • Palo Alto, California • Newark, Delaware + 17 more
Source: ClinicalTrials.gov public record
Updated Nov 20, 2008 · Synced Oct 18, 2026, 6:21 AM EDT
Completed No phase listed Observational

LONGEVITY Study. Evaluation of the Device and Battery Longevity of Boston Scientific Market-released ICD and CRT-D Devices

NCT02091011
View directory record Official record
Conditions
Implantable Cardioverter Defibrillators, CRT-D Cardiac Resynchronization Therapy Defibrillator
Interventions
Not listed
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
Not listed
Enrollment
1,600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
51
States / cities
Birmingham, Alabama • Glendale, Arizona • Tucson, Arizona + 44 more
Source: ClinicalTrials.gov public record
Updated Aug 2, 2022 · Synced Oct 18, 2026, 6:21 AM EDT
Completed No phase listed Observational Results available

Advance Cardiac Resynchronization Therapy (CRT) Registry

NCT01805154
View directory record Official record
Conditions
Heart Failure
Interventions
CRT Patients
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
1,529 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
41
States / cities
Birmingham, Alabama • Huntsville, Alabama • Glendale, Arizona + 36 more
Source: ClinicalTrials.gov public record
Updated Aug 12, 2019 · Synced Oct 18, 2026, 6:21 AM EDT
Completed No phase listed Observational Results available

Quadripolar CRT-D On Currently Approved Lead SystemS

NCT02232984
View directory record Official record
Conditions
Heart Failure
Interventions
Not listed
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
749 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
60
States / cities
Gilbert, Arizona • Phoenix, Arizona • Yuma, Arizona + 49 more
Source: ClinicalTrials.gov public record
Updated Apr 9, 2019 · Synced Oct 18, 2026, 6:21 AM EDT
Terminated Not applicable Interventional Results available

Comparison of Cyanoacrylate Tissue Adhesive and Suture for Closure of Cardiac Device Pockets

NCT00674128
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Cyanoacrylate tissue adhesive (Dermabond), Polyglactin 910 suture (Vicryl)
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years and older
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 29, 2010 · Synced Oct 18, 2026, 6:21 AM EDT
Not listed Not applicable Interventional

POsition of Leads in Advanced heaRt Failure: the POLAR Study

NCT01515761
View directory record Official record
Conditions
Cardiac Resynchronization Therapy, Heart Failure
Interventions
Postero-lateral, Antero-Lateral
Procedure
Lead sponsor
Sergio Thal, M.D.
Federal
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
2
States / cities
Tucson, Arizona • Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 24, 2012 · Synced Oct 18, 2026, 6:21 AM EDT
Terminated Not applicable Interventional

Adaptive Cardiac Resynchronization Therapy in Patients With RBBB

NCT05936294
View directory record Official record
Conditions
Right Bundle-Branch Block
Interventions
Optimization of CRT Device
Diagnostic Test
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 89 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
2
States / cities
Little Rock, Arkansas • Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 7, 2023 · Synced Oct 18, 2026, 6:21 AM EDT
Completed Not applicable Interventional Results available

Multicenter Automatic Defibrillator Implantation Trial - Chemotherapy-Induced Cardiomyopathy

NCT02164721
View directory record Official record
Conditions
Cardiomyopathy
Interventions
Three-lead CRT-D (Defibrillator)
Device
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
9
States / cities
Los Angeles, California • Washington D.C., District of Columbia • Tampa, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Mar 4, 2020 · Synced Oct 18, 2026, 6:21 AM EDT
Completed Not applicable Interventional Results available

Sensor Optimization of Cardiac Resynchronization Therapy Response

NCT01832493
View directory record Official record
Conditions
Heart Failure
Interventions
Cardiac Resynchronization Therapy
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
3
States / cities
Des Moines, Iowa • Columbus, Ohio • Fairfield, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 29, 2016 · Synced Oct 18, 2026, 6:21 AM EDT