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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cardiogenic Shock Clear all
Completed No phase listed Observational Results available

National Cardiogenic Shock Initiative

NCT03677180
View directory record Official record
Conditions
Cardiogenic Shock, Acute Myocardial Infarction, STEMI - ST Elevation Myocardial Infarction, NSTEMI - Non-ST Segment Elevation MI, Heart Attack
Interventions
Not listed
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
406 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
75
States / cities
Birmingham, Alabama • Fayetteville, Arkansas • Little Rock, Arkansas + 61 more
Source: ClinicalTrials.gov public record
Updated Jun 30, 2025 · Synced Jul 23, 2026, 10:21 PM EDT
Active, not recruiting Not applicable Interventional

Augmented Pacing for Shock in the Cardiac Intensive Care Unit

NCT06713668
View directory record Official record
Conditions
Cardiogenic Shock, Bradycardia, Shock
Interventions
Backup Pacing Rate Change
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Jul 23, 2026, 10:21 PM EDT
Completed No phase listed Observational Results available

Physiologic Effect of Topical Nitroglycerin on Microcirculation Capacity in Patients With Circulatory Shock.

NCT05102734
View directory record Official record
Conditions
Circulatory Shock, Cardiovascular Shock
Interventions
Nitroglycerin Topical Product
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 80 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 31, 2024 · Synced Jul 23, 2026, 10:21 PM EDT
Terminated Not applicable Interventional Results available

Impella CP With VA ECMO for Cardiogenic Shock

NCT03431467
View directory record Official record
Conditions
Cardiogenic Shock
Interventions
Impella-CP LV Vent
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 18, 2025 · Synced Jul 23, 2026, 10:21 PM EDT
Completed Phase 2 Interventional

The Safety and Efficacy of Istaroxime for Pre-Cardiogenic Shock

NCT04325035
View directory record Official record
Conditions
Cardiogenic Shock
Interventions
Istaroxime, Placebo
Drug
Lead sponsor
Windtree Therapeutics
Industry
Eligibility
18 Years to 85 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 3, 2025 · Synced Jul 23, 2026, 10:21 PM EDT
Recruiting Not applicable Interventional

Pulmonary Artery Catheter in Cardiogenic Shock Trial

NCT05485376
View directory record Official record
Conditions
Cardiogenic Shock, Heart Failure
Interventions
Pulmonary Artery Catheter
Device
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years to 90 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 28, 2025 · Synced Jul 23, 2026, 10:21 PM EDT
Not listed No phase listed Observational

Pressure Volume Loop

NCT04478188
View directory record Official record
Conditions
Cardiogenic Shock, Decompensated Heart Failure
Interventions
Measuring Pressure Volume Loop Pre and Post Device Placement
Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
150 participants
Timeline
2020 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 19, 2020 · Synced Jul 23, 2026, 10:21 PM EDT
Recruiting No phase listed Observational

Changes in Skeletal Muscle Thickness in Patients With Acute Heart Failure

NCT06253104
View directory record Official record
Conditions
Heart Failure, Muscle Atrophy, Skeletal Muscle Atrophy, Cardiogenic Shock
Interventions
BodyMetrix Body Composition Ultrasound
Diagnostic Test
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years to 100 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 22, 2025 · Synced Jul 23, 2026, 10:21 PM EDT
Recruiting No phase listed Observational

Inova Cardiogenic Shock Registry (INOVA SHOCK)

NCT03378739
View directory record Official record
Conditions
Cardiogenic Shock
Interventions
Cardiogenic Shock team activation
Procedure
Lead sponsor
Inova Health Care Services
Other
Eligibility
18 Years to 85 Years
Enrollment
3,000 participants
Timeline
2018 – 2099
U.S. locations
1
States / cities
Falls Church, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Jul 23, 2026, 10:21 PM EDT
Recruiting Not applicable Interventional

Hemodynamic Monitoring to Prevent Adverse Events foLlowing cardiOgenic Shock Trial

NCT04419480
View directory record Official record
Conditions
Cardiogenic Shock, Heart Failure, Ambulatory Hemodynamic Monitoring
Interventions
CardioMEMS implantation with routine ambulatory pulmonary artery pressure monitoring and medication optimization
Device
Lead sponsor
Inova Health Care Services
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2028
U.S. locations
1
States / cities
Falls Church, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Jul 23, 2026, 10:21 PM EDT
Completed No phase listed Observational

SURPASS Impella 5.5 Study

NCT05100836
View directory record Official record
Conditions
Cardiogenic Shock, Acute Decompensated Heart Failure
Interventions
Impella 5.5
Device
Lead sponsor
Abiomed Inc.
Industry
Eligibility
18 Years and older
Enrollment
1,017 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
15
States / cities
Los Angeles, California • Orlando, Florida • Tampa, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated May 19, 2025 · Synced Jul 23, 2026, 10:21 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Postoperative Respiratory Abnormalities

NCT04079829
View directory record Official record
Conditions
Respiratory Failure, Respiratory Arrest, Respiratory Distress Syndrome, Acute Respiratory Failure, Acute Respiratory Failure With Hypoxia, Acute Respiratory Failure With Hypercapnia, Acute Respiratory Failure Post Surgical, Acute Respiratory Failure Postprocedural, Acute Respiratory Failure Following Trauma and Surgery, Acute Respiratory Failure Requiring Reintubation, Acute Respiratory Failure Post Traumatic, Acute Respiratory Decompensation, Shock, Shock, Septic, Shock, Cardiogenic, Acute Cardiac Failure, Multi Organ Failure, Acute Kidney Failure
Interventions
Observational retrospective cohort to describe data validity; and Data reliability; and Completeness of the data
Other
Lead sponsor
Efficacy Care R&D Ltd
Industry
Eligibility
18 Years to 90 Years
Enrollment
50,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 23, 2020 · Synced Jul 23, 2026, 10:21 PM EDT
Recruiting Phase 4 Interventional

CAPITAL DOREMI 2: Inotrope Versus Placebo Therapy for Cardiogenic Shock

NCT05267886
View directory record Official record
Conditions
Shock, Cardiogenic
Interventions
Dobutamine, Milrinone, Normal Saline
Drug
Lead sponsor
Ottawa Heart Institute Research Corporation
Other
Eligibility
18 Years and older
Enrollment
346 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Jul 23, 2026, 10:21 PM EDT
Recruiting Early Phase 1 Interventional

Cardiac Power Output in Cardiogenic Shock Patients

NCT05700617
View directory record Official record
Conditions
Heart Failure, Cardiogenic Shock
Interventions
1:1 Randomization to receive milrinone
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 7, 2025 · Synced Jul 23, 2026, 10:21 PM EDT
Terminated Not applicable Interventional Results available

Early Insertion of Axillary Impella® With VA ECMO

NCT04084015
View directory record Official record
Conditions
Cardiogenic Shock
Interventions
Axillary Impella®
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 28, 2021 · Synced Jul 23, 2026, 10:21 PM EDT
Terminated No phase listed Observational

The Nanowear Wearable System SimpleSense Validation Trial for Cardiac Output

NCT05629533
View directory record Official record
Conditions
Right Heart Catheterization
Interventions
SimpleSense
Device
Lead sponsor
Nanowear Inc.
Industry
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Valhalla, New York
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Jul 23, 2026, 10:21 PM EDT
Active, not recruiting No phase listed Observational

Can Escalation Reduce Acute Myocardial Infarction Mortality in Cardiogenic Shock

NCT05800951
View directory record Official record
Conditions
Cardiogenic Shock, Acute Myocardial Infarction, STEMI - ST Elevation Myocardial Infarction, NSTEMI - Non-ST Segment Elevation MI, STEMI, NSTEMI, Acute Myocardial Infarction of Right Ventricle (Disorder), Acute Myocardial Infarction of Left Ventricle, Acute Myocardial Infarction With ST Elevation
Interventions
Not listed
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
17
States / cities
Loma Linda, California • Los Angeles, California • Orange, California + 12 more
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Jul 23, 2026, 10:21 PM EDT
Completed Not applicable Interventional

Cardiovascular Magnetic Resonance Prognosticators in Pediatric Oncology Patients With Sepsis

NCT05930418
View directory record Official record
Conditions
Acute Respiratory Distress Syndrome, Sepsis, Cardiovascular Shock
Interventions
Cardiac MRI
Diagnostic Test
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
9 Years to 25 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Jul 23, 2026, 10:21 PM EDT
Recruiting Not applicable Interventional

Transcatheter Mitral Valve Repair for Inotrope Dependent Cardiogenic Shock

NCT05298124
View directory record Official record
Conditions
Cardiogenic Shock, Mitral Regurgitation
Interventions
Transcatheter edge-to-edge repair, Medical therapy
Device · Other
Lead sponsor
Ottawa Heart Institute Research Corporation
Other
Eligibility
18 Years and older
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Jul 23, 2026, 10:21 PM EDT
Not listed Phase 4 Interventional

Effect of Ivabradine in Stage D HF/Cardiogenic Shock Patients on Dobutamine

NCT03387605
View directory record Official record
Conditions
Heart Failure, Cardiogenic Shock, Tachycardia
Interventions
Ivabradine, Placebo
Drug
Lead sponsor
Loyola University
Other
Eligibility
18 Years to 99 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated May 22, 2019 · Synced Jul 23, 2026, 10:21 PM EDT
Terminated Phase 3 Interventional

A Study of the Safety and Efficacy of Nitric Oxide Reduction in Patients With Cardiogenic Shock After a Heart Attack

NCT00112281
View directory record Official record
Conditions
Shock, Cardiogenic
Interventions
Tilarginine Acetate Injection intravenous infusion
Drug
Lead sponsor
Arginox Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
658 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
83
States / cities
Mobile, Alabama • Fort Smith, Arizona • Mesa, Arizona + 68 more
Source: ClinicalTrials.gov public record
Updated Aug 3, 2006 · Synced Jul 23, 2026, 10:21 PM EDT
Withdrawn No phase listed Observational

Establishing Physiologic Outcomes for Ventricular Unloading on VA ECMO

NCT05658276
View directory record Official record
Conditions
Cardiogenic Shock
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 11, 2024 · Synced Jul 23, 2026, 10:21 PM EDT
Not yet recruiting Not applicable Interventional

INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac Recovery

NCT06965504
View directory record Official record
Conditions
Heart Failure, Cardiogenic Shock, Reduced Ejection Fraction Heart Failure
Interventions
Impella 5.5 SmartAssist
Device
Lead sponsor
Abiomed Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
7
States / cities
Tampa, Florida • Minneapolis, Minnesota • New Brunswick, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Jul 23, 2026, 10:21 PM EDT
Completed No phase listed Observational

"Treatment Use of ECMO In Pregnancy or Peripartum Patient."

NCT04144660
View directory record Official record
Conditions
Cardiogenic Shock, Peripartum Cardiomyopathy, Complication, Pregnancy
Interventions
Extracorporeal Membrane Oxygenation
Device
Lead sponsor
Sarah Thordsen
Other
Eligibility
18 Years and older · Female only
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 22, 2020 · Synced Jul 23, 2026, 10:21 PM EDT