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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cardiogenic Shock Clear all
Terminated No phase listed Observational

The Nanowear Wearable System SimpleSense Validation Trial for Cardiac Output

NCT05629533
View directory record Official record
Conditions
Right Heart Catheterization
Interventions
SimpleSense
Device
Lead sponsor
Nanowear Inc.
Industry
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Valhalla, New York
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Sep 23, 2026, 8:05 AM EDT
Withdrawn Not applicable Interventional

Incorporating Supersaturated Oxygen in Shock

NCT04876040
View directory record Official record
Conditions
Cardiogenic Shock, STEMI
Interventions
SSO2 Downstream System, PCI + Impella
Device · Procedure
Lead sponsor
TherOx
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
7
States / cities
Miami, Florida • Springfield, Massachusetts • Detroit, Michigan + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 23, 2024 · Synced Sep 23, 2026, 8:05 AM EDT
Recruiting No phase listed Observational

Multi-center Collaborative to Enhance Quality and Outcomes in the Management of Cardiogenic Shock

NCT05185492
View directory record Official record
Conditions
Cardiogenic Shock, Acute Myocardial Infarction
Interventions
Not listed
Lead sponsor
STAVROS G DRAKOS
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Weston, Florida • Falls Church, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Sep 23, 2026, 8:05 AM EDT
Completed No phase listed Observational Results available

Physiologic Effect of Topical Nitroglycerin on Microcirculation Capacity in Patients With Circulatory Shock.

NCT05102734
View directory record Official record
Conditions
Circulatory Shock, Cardiovascular Shock
Interventions
Nitroglycerin Topical Product
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 80 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 31, 2024 · Synced Sep 23, 2026, 8:05 AM EDT
Recruiting Phase 4 Interventional

CAPITAL DOREMI 2: Inotrope Versus Placebo Therapy for Cardiogenic Shock

NCT05267886
View directory record Official record
Conditions
Shock, Cardiogenic
Interventions
Dobutamine, Milrinone, Normal Saline
Drug
Lead sponsor
Ottawa Heart Institute Research Corporation
Other
Eligibility
18 Years and older
Enrollment
346 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 23, 2026, 8:05 AM EDT
Recruiting No phase listed Observational

Assessment of Support With Impella® Best Practices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

NCT06964685
View directory record Official record
Conditions
AMI Cardiogenic Shock
Interventions
Impella
Device
Lead sponsor
Abiomed Inc.
Industry
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
18
States / cities
Jonesboro, Arkansas • Orange, California • Torrance, California + 14 more
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 23, 2026, 8:05 AM EDT
Active, not recruiting Phase 1Phase 2 Interventional

A Safety and Efficacy Trial of Istaroxime for Cardiogenic Shock Stage C

NCT05975021
View directory record Official record
Conditions
Cardiogenic Shock
Interventions
Istaroxime, Placebo
Drug
Lead sponsor
Windtree Therapeutics
Industry
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Boston, Massachusetts • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 19, 2025 · Synced Sep 23, 2026, 8:05 AM EDT
Recruiting Early Phase 1 Interventional

Cardiac Power Output in Cardiogenic Shock Patients

NCT05700617
View directory record Official record
Conditions
Heart Failure, Cardiogenic Shock
Interventions
1:1 Randomization to receive milrinone
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Sep 23, 2026, 8:05 AM EDT
Recruiting Phase 2 Interventional

Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System

NCT06080074
View directory record Official record
Conditions
Heart Failure, Cardiogenic Shock, Congenital Heart Disease, Cardiomyopathies
Interventions
Cardiohelp device (VA-ECMO), Heparin, Bivalirudin
Device · Drug
Lead sponsor
Stanford University
Other
Eligibility
0 Years to 16 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
5
States / cities
Palo Alto, California • New York, New York • Durham, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 23, 2026, 8:05 AM EDT
Terminated Phase 2 Interventional

The Effects of Nitric Oxide for Inhalation in Right Ventricular Infarction Patients

NCT00782652
View directory record Official record
Conditions
Right Ventricular Infarction
Interventions
inhaled nitric oxide, nitrogen gas
Drug
Lead sponsor
Mallinckrodt
Industry
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
2
States / cities
Boston, Massachusetts • Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 8, 2016 · Synced Sep 23, 2026, 8:05 AM EDT
Completed No phase listed Observational

Carolinas Cardiogenic Shock Initiative

NCT04985708
View directory record Official record
Conditions
Cardiogenic Shock, Acute; Myocardial Infarction, Complications
Interventions
data collection of clinically available procedures
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 5, 2022 · Synced Sep 23, 2026, 8:05 AM EDT
Terminated Not applicable Interventional Results available

Early Insertion of Axillary Impella® With VA ECMO

NCT04084015
View directory record Official record
Conditions
Cardiogenic Shock
Interventions
Axillary Impella®
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 28, 2021 · Synced Sep 23, 2026, 8:05 AM EDT
Terminated Not applicable Interventional Results available

Impella CP With VA ECMO for Cardiogenic Shock

NCT03431467
View directory record Official record
Conditions
Cardiogenic Shock
Interventions
Impella-CP LV Vent
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 18, 2025 · Synced Sep 23, 2026, 8:05 AM EDT
Recruiting No phase listed Observational

Inova Cardiogenic Shock Registry (INOVA SHOCK)

NCT03378739
View directory record Official record
Conditions
Cardiogenic Shock
Interventions
Cardiogenic Shock team activation
Procedure
Lead sponsor
Inova Health Care Services
Other
Eligibility
18 Years to 85 Years
Enrollment
3,000 participants
Timeline
2018 – 2099
U.S. locations
1
States / cities
Falls Church, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Sep 23, 2026, 8:05 AM EDT
Completed Not applicable Interventional Results available

Cardiogenic Shock Intravascular Cooling Trial

NCT03141255
View directory record Official record
Conditions
Cardiogenic Shock
Interventions
IVTM™ System, Quattro® Catheter
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 89 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 11, 2023 · Synced Sep 23, 2026, 8:05 AM EDT
Active, not recruiting Not applicable Interventional

Augmented Pacing for Shock in the Cardiac Intensive Care Unit

NCT06713668
View directory record Official record
Conditions
Cardiogenic Shock, Bradycardia, Shock
Interventions
Backup Pacing Rate Change
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 23, 2026, 8:05 AM EDT
Completed No phase listed Observational

PPCM Observational Study (Peripartum Cardiomyopathy)

NCT04234659
View directory record Official record
Conditions
Peripartum Cardiomyopathy, Cardiogenic Shock
Interventions
Clinical placement of a temporary IMPELLA® mechanical circulatory support device.
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older · Female only
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 22, 2026 · Synced Sep 23, 2026, 8:05 AM EDT
Withdrawn Phase 4 Interventional

Comparison of ARNI to Alternate Oral Vasodilator Therapies in Patients With Low Cardiac Output

NCT04206865
View directory record Official record
Conditions
Cardiogenic Shock
Interventions
Sacubitril-Valsartan, Standard Oral Vasodilators
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 4, 2020 · Synced Sep 23, 2026, 8:05 AM EDT
Completed No phase listed Observational

Left Ventricular Physiological Effects of Veno-Arterial Extracorporeal Membrane Oxygenation Support During Cardiogenic Shock

NCT05426083
View directory record Official record
Conditions
Acute Coronary Syndrome, Cardiogenic Shock
Interventions
Physiological Assessment
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Sep 23, 2026, 8:05 AM EDT
Withdrawn No phase listed Observational

Establishing Physiologic Outcomes for Ventricular Unloading on VA ECMO

NCT05658276
View directory record Official record
Conditions
Cardiogenic Shock
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 11, 2024 · Synced Sep 23, 2026, 8:05 AM EDT
Completed No phase listed Observational

RUral dispaRities in prehospitAL STEMI

NCT04381260
View directory record Official record
Conditions
ST Elevation Myocardial Infarction, Cardiovascular Diseases
Interventions
No intervention, Interview, Survey
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
473 participants
Timeline
2020 – 2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 26, 2024 · Synced Sep 23, 2026, 8:05 AM EDT
Recruiting No phase listed Observational

Pre-Emptive LAVA-ECMO for Complex High-Risk TAVR

NCT07309029
View directory record Official record
Conditions
Severe Aortic Stenosis, Cardiogenic Shock, Cardiogenic Shock, ECMO, Trans-catheter Aortic Valve Implantation
Interventions
Left Atrial Veno-Arterial Extracorporeal Membrane Oxygenation (LAVA-ECMO)
Device
Lead sponsor
Atlantic Health System
Other
Eligibility
18 Years to 100 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Detroit, Michigan • Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 29, 2025 · Synced Sep 23, 2026, 8:05 AM EDT
Completed No phase listed Observational

Impella Real-World Surveillance of Patients Using Sodium Bicarbonate

NCT05820451
View directory record Official record
Conditions
Cardiogenic Shock, High Risk PCI
Interventions
Impella CP, 2.5, 5.0 and 5.5 with Sodium Bicarbonate used as purge solution, Impella RP with Sodium Bicarbonate used as purge solution
Device
Lead sponsor
Abiomed Inc.
Industry
Eligibility
Not listed
Enrollment
312 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
20
States / cities
Birmingham, Alabama • Tucson, Arizona • Little Rock, Arkansas + 14 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2024 · Synced Sep 23, 2026, 8:05 AM EDT
Terminated Phase 3 Interventional

A Study of the Safety and Efficacy of Nitric Oxide Reduction in Patients With Cardiogenic Shock After a Heart Attack

NCT00112281
View directory record Official record
Conditions
Shock, Cardiogenic
Interventions
Tilarginine Acetate Injection intravenous infusion
Drug
Lead sponsor
Arginox Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
658 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
83
States / cities
Mobile, Alabama • Fort Smith, Arizona • Mesa, Arizona + 68 more
Source: ClinicalTrials.gov public record
Updated Aug 3, 2006 · Synced Sep 23, 2026, 8:05 AM EDT