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ClinicalTrials.gov public records Last synced Sep 15, 2026, 6:16 PM EDT

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Showing 1–24 of 312 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cardiometabolic Diseases Clear all
Completed Not applicable Interventional Results available

Impact of Passive Heat on Metabolic, Inflammatory and Vascular Health in Persons With Spinal Cord Injury

NCT04971408
View directory record Official record
Conditions
Spinal Cord Injury, Chronic Inflammation, Glucose Metabolism, Endothelial Function
Interventions
passive heat stress, Control
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Sep 15, 2026, 6:16 PM EDT
Enrolling by invitation No phase listed Observational

Adult Sleep Health in the Rural Appalachia and Mississippi Delta Region and Its Relationships With Cardiometabolic Health Disparities.

NCT06336525
View directory record Official record
Conditions
Sleep Apnea, Insomnia, Sleep Deprivation, Sleep Disorders, Circadian Rhythm, Sleepiness, Excessive Daytime, Fatigue
Interventions
Not listed
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
25 Years to 65 Years
Enrollment
3,680 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 26, 2025 · Synced Sep 15, 2026, 6:16 PM EDT
Not listed Not applicable Interventional

Cardiometabolic Syndrome Response to Therapeutic Lifestyle Changes

NCT04093440
View directory record Official record
Conditions
Metabolic Syndrome, ASCVD, Lifestyle Risk Reduction
Interventions
lifestyle modification
Other
Lead sponsor
Holy Cross Hospital, Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Source: ClinicalTrials.gov public record
Updated Sep 17, 2019 · Synced Sep 15, 2026, 6:16 PM EDT
Completed Not applicable Interventional

Effect of Egg Consumption on Cardiometabolic Health in Prediabetic Subjects.

NCT03332927
View directory record Official record
Conditions
PreDiabetes
Interventions
Egg based breakfast foods, Non-egg based breakfast foods
Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
18 Years to 74 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 23, 2019 · Synced Sep 15, 2026, 6:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cardiometabolic Effects of Sweet Cherry Juice

NCT03948061
View directory record Official record
Conditions
Obesity, Metabolic Syndrome
Interventions
Cherry juice, Placebo beverage
Other
Lead sponsor
USDA, Western Human Nutrition Research Center
Federal
Eligibility
20 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Oct 26, 2023 · Synced Sep 15, 2026, 6:16 PM EDT
Recruiting Phase 2 Interventional

Combined Oral Contraceptive Pill and Resistance Starch

NCT06852365
View directory record Official record
Conditions
Metabolic Syndrome, Polycystic Ovary Syndrome
Interventions
wheat dextrin, Oral Contraceptives, Low-Dose, Maltodextrin
Dietary Supplement · Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 31, 2026 · Synced Sep 15, 2026, 6:16 PM EDT
Withdrawn Phase 4 Interventional

A Single-arm Evaluation of the Effect of HCV Treatment on Cardiovascular Disease Risk

NCT03585101
View directory record Official record
Conditions
Hepatitis C
Interventions
Elbasvir/grazoprevir
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 6, 2018 · Synced Sep 15, 2026, 6:16 PM EDT
Completed Not applicable Interventional

TREAT to Improve Cardiometabolic Health

NCT04465721
View directory record Official record
Conditions
Overweight and Obesity, Prediabetes
Interventions
TRE, HABIT
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
50 Years to 75 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 15, 2026, 6:16 PM EDT
Terminated Not applicable Interventional Results available

Activity and Balanced Eating to Reduce Comorbidities and Symptoms of MS

NCT03808545
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Behavioral Intervention for Physical Activity in Multiple Sclerosis (BIPAMS), BIPAMS + Diet
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 17, 2022 · Synced Sep 15, 2026, 6:16 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Effects of Estrogen on Heart Health in Women With Primary Ovarian Insufficiency

NCT06866119
View directory record Official record
Conditions
Primary Ovarian Insufficiency, Premature Menopause, Metabolic Complications, Endothelial Function (FMD), Estrogen Replacement Therapy
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
30 Years to 40 Years · Female only
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 7, 2026 · Synced Sep 15, 2026, 6:16 PM EDT
Recruiting No phase listed Observational

Pubertal Blockade and Estradiol Effects on Cardiometabolic Health for Transitioning Youth

NCT04596592
View directory record Official record
Conditions
Transgenderism, Gender Dysphoria, Insulin Sensitivity
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
13 Years to 16 Years
Enrollment
90 participants
Timeline
2021 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 9, 2025 · Synced Sep 15, 2026, 6:16 PM EDT
Completed Not applicable Interventional

SUSTAIN: Behavior Change and Nutrition Security for CKMS

NCT06589336
View directory record Official record
Conditions
Stage 2 Cardiovascular-Kidney-Metabolic Syndrome, Cardiovascular Disease Other
Interventions
Dietary changes via Instacart vouchers, Dietary changes via access to Mid-Ohio Farmacy, Behavior changes via access to Health Impact Ohio Hub, Behavioral nutrition counseling, Cooking classes, Dietary changes to Delivery fees
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Sep 15, 2026, 6:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Adding L-BAIBA or L-BAIBA + Grains of Paradise to Exercising Adult Overweight and Obese Men and Women

NCT05775003
View directory record Official record
Conditions
Obese, Weight Loss, Body Weight, Cardiometabolic Syndrome
Interventions
Exercise
Dietary Supplement
Lead sponsor
Lindenwood University
Other
Eligibility
18 Years to 60 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Saint Charles, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced Sep 15, 2026, 6:16 PM EDT
Not yet recruiting No phase listed Observational

A Natural History of Cardiometabolic Disease Among US Bhutanese: Developing the Cross-Sectional Bhutanese Community of Central Ohio Health Study to Understand Acculturation as Synergizing Socioenvironmental and Biobehavioral Risk Factors Propagating ...

NCT06991751
View directory record Official record
Conditions
Cardiometabolic Risk Factors, Mental Health
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
18 Years to 100 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Sep 15, 2026, 6:16 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Pathogenesis of the Cardiometabolic Risk in Youth With Type 1 Diabetes

NCT04101045
View directory record Official record
Conditions
Type 1 Diabetes, De Novo Lipogenesis
Interventions
Oral Glucose Tolerance Test
Diagnostic Test
Lead sponsor
Yale University
Other
Eligibility
13 Years to 22 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 12, 2023 · Synced Sep 15, 2026, 6:16 PM EDT
Recruiting Not applicable Interventional

Enjoying Affordable and Tasty Food Together

NCT07036757
View directory record Official record
Conditions
Food Insecurity, Dietary Quality, Quality of Life, Cooking Self-efficacy, Perceived Stress, Anxiety, Depressive Symptomatology, Anthropometrics: Height and Weight, Glucose Variability, Blood Pressure
Interventions
Meal Kit and Nutrition Education
Other
Lead sponsor
University of Massachusetts, Lowell
Other
Eligibility
40 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Lowell, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 15, 2026, 6:16 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Stepping Into Lifestyle Changes

NCT05625321
View directory record Official record
Conditions
Overweight and Obesity, Pre-Diabetes, High Blood Pressure
Interventions
Educational Group Weight Loss Classes, Home Gardening Intervention
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
30 Years and older · Female only
Enrollment
273 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
2
States / cities
Birmingham, Alabama • Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Aug 26, 2025 · Synced Sep 15, 2026, 6:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

WorkWell: Work-based Activity and Metabolic Health

NCT04269070
View directory record Official record
Conditions
PreDiabetes, Obesity
Interventions
Standing condition, Light physical activity (LPA) condition, Usual behavior condition
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated May 9, 2023 · Synced Sep 15, 2026, 6:16 PM EDT
Completed Not applicable Interventional

Egg Ingestion in Adults With Type 2 Diabetes

NCT02052037
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Egg inclusion, Egg exclusion
Dietary Supplement
Lead sponsor
Griffin Hospital
Other
Eligibility
35 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Derby, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 5, 2017 · Synced Sep 15, 2026, 6:16 PM EDT
Recruiting Not applicable Interventional

Improving Heart Health in Individuals With SCI Using Home-Based Virtual Gaming

NCT06690372
View directory record Official record
Conditions
Spinal Cord Injuries (SCI)
Interventions
virtual reality exercise
Other
Lead sponsor
Drexel University
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Sep 15, 2026, 6:16 PM EDT
Terminated Phase 4 Interventional Results available

Examining Genetic Influence on Response to Beta-Blocker Medications in People With Type 2 Diabetes

NCT00925119
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Atenolol
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
21 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 25, 2019 · Synced Sep 15, 2026, 6:16 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Building Access to Food Through Systems and Solidarity (BASIS): A Subsidized and Culturally-adapted Produce Box Program for Immigrant Communities of Brooklyn, NY

NCT07076251
View directory record Official record
Conditions
Cardiometabolic Disease
Interventions
Family Box program
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 90 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 15, 2026, 6:16 PM EDT
Not yet recruiting No phase listed Observational

Scale-Up Evaluation Trial of the Diabetes Prevention Program to Improve Obesity and Cardiometabolic Health After Traumatic Brain Injury

NCT07648901
View directory record Official record
Conditions
Traumatic Brain Injury, Brain Injuries, Traumatic, Brain Injury, Chronic
Interventions
Group Lifestyle Balance for People with TBI (GLB-TBI)
Behavioral
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 80 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Sep 15, 2026, 6:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family Weight Management Study

NCT00851201
View directory record Official record
Conditions
Obesity, Diabetes
Interventions
Intensive lifestyle, Standard intervention
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
7 Years to 12 Years
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 17, 2017 · Synced Sep 15, 2026, 6:16 PM EDT