Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Jun 10, 2026, 7:55 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Conditions
Diabetes Mellitus, Diabetes Mellitus, Type 2, PreDiabetes, Hypertension, High Blood Pressure, High Blood Sugar, Obesity, Overweight, Overweight and Obesity, Overweight or Obesity
Interventions
The Diabetes Prevention Program
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
25 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Stage 2 Cardiovascular-Kidney-Metabolic Syndrome, Cardiovascular Disease Other
Interventions
Dietary changes via Instacart vouchers, Dietary changes via access to Mid-Ohio Farmacy, Behavior changes via access to Health Impact Ohio Hub, Behavioral nutrition counseling, Cooking classes, Dietary changes to Delivery fees
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Cardiovascular Diseases
Interventions
Walnuts, No-nut diet
Dietary Supplement
Lead sponsor
University of California, Davis
Other
Eligibility
45 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Davis, California
Completed Not applicable Interventional Accepts healthy volunteers

Nutrition, Body Composition, and Sleep

NCT03603041
Conditions
Sleep, Body Composition, Strength, Insulin Sensitivity, Energy Expenditure
Interventions
Whey protein, Omega-3 fatty acids
Dietary Supplement
Lead sponsor
University of Arkansas, Fayetteville
Other
Eligibility
Up to 85 Years · Female only
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Fayetteville, Arkansas
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Chronic Energy Drink Consumption on Cardiometabolic Endpoints

NCT03840863
Conditions
Cardiovascular Diseases
Interventions
Commercially-Available Energy Drink
Dietary Supplement
Lead sponsor
University of the Pacific
Other
Eligibility
18 Years to 40 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Stockton, California
Not listed Phase 3 Interventional Accepts healthy volunteers

Effect of Melatonin on Cardiometabolic Risk- FULL

NCT02681887
Conditions
Obesity, Prediabetic State
Interventions
Melatonin, Placebo
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Cerebral Palsy
Interventions
Sprint-Intensity Interval Training with Telecoaching
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
6 Years to 17 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Homewood, Alabama
Conditions
Overweight or Obesity, Prediabetes or Diabetes, Prehypertension (Elevated Blood Pressure) or Hypertension, Resistance Training
Interventions
Resistance Training
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
30 Years to 64 Years · Female only
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Recruiting No phase listed Observational

The Weight of Cardiovascular Disease

NCT06053645
Conditions
Cardiovascular Diseases, Obesity
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Obesity and Obesity-related Medical Conditions, Diabetes, Atherosclerotic Disease, Heart Failure, MASH, Sarcopenia, Osteoporosis, Hyperparathyroidism, Hypoparathyroidism, Ischemic Heart Disease, Cystic Fibrosis (CF), Chronic Kidney Disease(CKD), Osteopenia, Cachexia
Interventions
Endothelial cell collection
Other
Lead sponsor
Bettina Mittendorfer
Other
Eligibility
18 Years to 100 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2030
U.S. locations
1
States / cities
Columbia, Missouri
Conditions
Psoriasis, Atherosclerotic Cardiovascular Disease, Obesity, Dyslipidemia, Cardiometabolic Diseases
Interventions
Niagen, Placebo
Dietary Supplement · Other
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years to 80 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Bethesda, Maryland
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Stepping Into Lifestyle Changes

NCT05625321
Conditions
Overweight and Obesity, Pre-Diabetes, High Blood Pressure
Interventions
Educational Group Weight Loss Classes, Home Gardening Intervention
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
30 Years and older · Female only
Enrollment
273 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
2
States / cities
Birmingham, Alabama • Jackson, Mississippi
Conditions
Food Insecurity, Overweight, Obesity, Cardiometabolic Syndrome
Interventions
Weekly Family Food Packages, Family Health Group Sessions
Other · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
Not listed
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Revere, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

Family Weight Management Study

NCT00851201
Conditions
Obesity, Diabetes
Interventions
Intensive lifestyle, Standard intervention
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
7 Years to 12 Years
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
The Bronx, New York
Completed No phase listed Observational Accepts healthy volunteers

Direct Measurements of Cardiometabolic Risk in Treated Schizophrenia Patients

NCT00501163
Conditions
Schizophrenia, Cardiovascular Disease
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
10 Years to 55 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Heart Failure
Interventions
THRV-1268, Placebo
Drug
Lead sponsor
Thryv Therapeutics, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Overland Park, Kansas
Completed No phase listed Observational Accepts healthy volunteers Results available

Relative Sarcopenia and Cardiometabolic Risk in Young Adults With Obesity

NCT04195061
Conditions
Overweight and Obesity, Insulin Resistance
Interventions
Cardiopulmonary exercise test (CPET)
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Completed No phase listed Observational Accepts healthy volunteers

Shape Up Kids Fitness Ancillary

NCT03624582
Conditions
Childhood Obesity
Interventions
Not listed
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
8 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Conditions
Postpartum Depression, Postpartum Anxiety, Cardiometabolic Syndrome
Interventions
MOMI PODS, Enhanced Usual Care (EUC)
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
Female only
Enrollment
384 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Completed Phase 1 Interventional Accepts healthy volunteers

Enhancing Efficacy of Mango Polyphenols in Lean and Obese

NCT04970589
Conditions
Obesity
Interventions
Mango, Probiotics, Placebo
Other · Dietary Supplement
Lead sponsor
Texas A&M University
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
College Station, Texas
Completed Not applicable Interventional Results available

Nuts and Oil Pilot Study

NCT04361617
Conditions
Metabolic Syndrome
Interventions
Daily consumption of tree nuts and extra virgin olive oil
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
35 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
ASCVD, Hyperlipidemia, Hypertension
Interventions
Referral to the Duke Cardiometabolic Prevention Clinic
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Food Insecurity, Dietary Quality, Quality of Life, Cooking Self-efficacy, Perceived Stress, Anxiety, Depressive Symptomatology, Anthropometrics: Height and Weight, Glucose Variability, Blood Pressure
Interventions
Meal Kit and Nutrition Education
Other
Lead sponsor
University of Massachusetts, Lowell
Other
Eligibility
40 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Lowell, Massachusetts
Conditions
Hypertension, Gut Dysbiosis, Overweight , Obesity
Interventions
Synbiotic, Placebo
Dietary Supplement
Lead sponsor
Southern Utah University
Other
Eligibility
18 Years to 60 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Cedar, Utah