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ClinicalTrials.gov public records Last synced Oct 20, 2026, 2:40 AM EDT

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Showing 1–24 of 147 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Cardiometabolic Risk Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Mindfulness-based Personalized Health Planning for Reducing Risk of Heart Disease and Diabetes

NCT01430221
View directory record Official record
Conditions
Prediabetes, Depressive Symptoms Mild to Moderate in Severity
Interventions
Mindfulness-based Personalized Health Planning, Structured & Guided Education
Behavioral · Other
Lead sponsor
Duke University
Other
Eligibility
30 Years to 70 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 24, 2017 · Synced Oct 20, 2026, 2:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Low-Insulinemic Dietary Intervention to Reduce Breast Cancer Risk in High-Risk Women

NCT06635005
View directory record Official record
Conditions
Feasibility Pilot Study, Compliance
Interventions
Biospecimen Collection, Dietary Intervention, Medical Device Usage and Evaluation, Motivational Interviewing, Nutritional Assessment, Questionnaire Administration
Procedure · Other · Behavioral
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
45 Years and older · Female only
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Oct 20, 2026, 2:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Role of Immune System in Obesity-related Inflammation and Cardiometabolic Risk

NCT01104220
View directory record Official record
Conditions
Non-alcoholic Fatty Liver Disease, Metabolic Syndrome, Metabolically Abnormal Obesity, Metabolically Normal Obesity, Obesity
Interventions
Weight loss
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 90 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2025
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 20, 2026, 2:40 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Dietary Fiber Effects on the Microbiome and Satiety

NCT04611217
View directory record Official record
Conditions
Dietary Fiber
Interventions
Dietary fiber: 10-25g, Dietary fiber: 5g
Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
20 Years to 55 Years
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 22, 2025 · Synced Oct 20, 2026, 2:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Magnesium and Vitamin D Supplementation and Cardiometabolic Outcomes

NCT03134417
View directory record Official record
Conditions
Overweight and Obesity, Vitamin D Deficiency, Magnesium Deficiency, Cardiovascular Risk Factor
Interventions
Vitamin D and magnesium, Vitamin D, Placebo
Dietary Supplement
Lead sponsor
Drexel University
Other
Eligibility
30 Years to 70 Years
Enrollment
109 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 27, 2021 · Synced Oct 20, 2026, 2:40 AM EDT
Enrolling by invitation No phase listed Observational

Trajectory Study: Predicting Cardiometabolic Health in Adolescents and Young Adults Based on Childhood Fitness, Sleep, and Diet

NCT06913985
View directory record Official record
Conditions
Cardiometabolic Health
Interventions
Not listed
Lead sponsor
Arkansas Children's Hospital Research Institute
Other
Eligibility
13 Years to 21 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
2
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jul 2, 2025 · Synced Oct 20, 2026, 2:40 AM EDT
Completed Phase 3 Interventional Results available

SGA-induced Metabolic Syndrome in Bipolar Youth

NCT01858948
View directory record Official record
Conditions
Bipolar Youth Treated With Second-generation Antipsychotics
Interventions
Omega, Placebo, Quetiapine fumarate
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
10 Years to 17 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 25, 2022 · Synced Oct 20, 2026, 2:40 AM EDT
Not listed No phase listed Observational

Cardiometabolic Risk in Cardiac Rehab

NCT01985048
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Not listed
Lead sponsor
Health Diagnostic Laboratory, Inc.
Industry
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
3
States / cities
Camp Hill, Pennsylvania • Ephrata, Pennsylvania • Lancaster, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 13, 2015 · Synced Oct 20, 2026, 2:40 AM EDT
Not yet recruiting Phase 2Phase 3 Interventional

Postpartum Semaglutide to Reduce Cardiometabolic Risk After Gestational Diabetes Mellitus

NCT07797036
View directory record Official record
Conditions
Gestational Diabetes Mellitus (GDM), Metabolic Syndrome
Interventions
Semaglutide (Wegovy) weekly injection
Drug
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older · Female only
Enrollment
226 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 20, 2026, 2:40 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Relative Sarcopenia and Cardiometabolic Risk in Young Adults With Obesity

NCT04195061
View directory record Official record
Conditions
Overweight and Obesity, Insulin Resistance
Interventions
Cardiopulmonary exercise test (CPET)
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 30, 2024 · Synced Oct 20, 2026, 2:40 AM EDT
Recruiting Not applicable Interventional

MegaNatural BP® GSE on Blood Pressure and Cardiometabolic Risk Factors

NCT06555952
View directory record Official record
Conditions
Hypertension, Pre Diabetes
Interventions
MegaNatural-BP SR 150Mg Tablet, Placebo Capsule
Dietary Supplement · Other
Lead sponsor
Clinical Nutrition Research Center, Illinois Institute of Technology
Industry
Eligibility
40 Years to 60 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 20, 2026, 2:40 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Lifestyle and Cardiometabolic Risk in Post-9/11 Veterans

NCT04911153
View directory record Official record
Conditions
PTSD, Cardiovascular Disease, Metabolic Syndrome
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 18, 2025 · Synced Oct 20, 2026, 2:40 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Trial of Pistachio Consumption in Older Adults

NCT06992544
View directory record Official record
Conditions
Cognition, Cardiometabolic Risk Factors, Life Satisfaction
Interventions
Pistachio-enriched diet, Usual diet
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
65 Years to 80 Years
Enrollment
97 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 20, 2026, 2:40 AM EDT
Completed Not applicable Interventional Results available

Feasibility Trial of a Stakeholder-enhanced Lay-navigator-delivered Intervention (ImPart-Multi)

NCT06067009
View directory record Official record
Conditions
Kidney Diseases, Cardiometabolic Risk Factors
Interventions
ImPart-Multi - IMproving the decisional PARTnership of Chronic Kidney Disease Dyads with concurrent metabolic disease
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Oct 20, 2026, 2:40 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Cognitive Strategies for Optimizing Brain Health And Managing Transgenerational Vascular Risk Factors Post-Stroke

NCT06479174
View directory record Official record
Conditions
Stroke, Ischemic
Interventions
CHAMPS-TR
Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 20, 2026, 2:40 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Trial to Examine the Effects of a Weight Loss Program Emphasizing Protein, Dietary Fiber, and Exercise (30-30-30 Plan)

NCT07789769
View directory record Official record
Conditions
Overweight , Obesity
Interventions
30-30-30 PFE Intervention, Standard
Behavioral
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
18 Years to 69 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
3
States / cities
Addison, Illinois • Chicago, Illinois • Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 20, 2026, 2:40 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Metabolic Wellness and CGM

NCT06790472
View directory record Official record
Conditions
Cardiometabolic Risk Factors
Interventions
Online Lifestyle Intervention, Continuous Glucose Monitoring
Behavioral · Device
Lead sponsor
David Kerr
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jan 24, 2025 · Synced Oct 20, 2026, 2:40 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Improving the Early Detection of Cardiometabolic Disease Risk

NCT05885672
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Online psychoeducational lifestyle intervention
Behavioral
Lead sponsor
University of Southern Mississippi
Other
Eligibility
18 Years to 39 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Hattiesburg, Mississippi
Source: ClinicalTrials.gov public record
Updated Jul 9, 2024 · Synced Oct 20, 2026, 2:40 AM EDT
Completed Not applicable Interventional Results available

Research Aimed at Improving Both Mood and Weight

NCT02246413
View directory record Official record
Conditions
Depression, Obesity
Interventions
RAINBOW Intervention Program
Behavioral
Lead sponsor
Palo Alto Medical Foundation
Other
Eligibility
18 Years and older
Enrollment
409 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
2
States / cities
Palo Alto, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Apr 26, 2024 · Synced Oct 20, 2026, 2:40 AM EDT
Recruiting Phase 2 Interventional

Obesity Complicating Type 1 Diabetes: GLP-1 Analogue Anti-obesity Treatment

NCT06411210
View directory record Official record
Conditions
Diabetes type1, Obesity
Interventions
Semaglutide Pen Injector, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 30 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Oct 20, 2026, 2:40 AM EDT
Completed Not applicable Interventional

Exergaming Intervention in ALL Patients

NCT02118324
View directory record Official record
Conditions
Acute Lymphoblastic Leukemia
Interventions
Exergaming Program
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
5 Years to 17 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 14, 2017 · Synced Oct 20, 2026, 2:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Macadamia Nut on Cardiometabolic Risk Factors

NCT03801837
View directory record Official record
Conditions
Cardiovascular Risk Factor, Heart Diseases, Inflammation
Interventions
Macadamia Nut, Control Diet
Dietary Supplement
Lead sponsor
Loma Linda University
Other
Eligibility
40 Years to 75 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced Oct 20, 2026, 2:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Virtual Enhanced Lifestyle for Metabolic Syndrome (ELM) Proof-of-Concept Study

NCT04637477
View directory record Official record
Conditions
Metabolic Syndrome, Obesity
Interventions
Virtual ELM
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
2
States / cities
Chicago, Illinois • Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 16, 2021 · Synced Oct 20, 2026, 2:40 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

HomeStyles-Adults of Chinese Heritage

NCT06136793
View directory record Official record
Conditions
Healthy Lifestyle, Home Environment Related Disease, Cardiometabolic Disease, Systemic Inflammatory Response, Health Behavior, Dietary Habits, Physical Inactivity, Self Efficacy, Gut Microbiota, Diabetes Mellitus
Interventions
HomeStyles-China
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
30 Years to 70 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Oct 20, 2026, 2:40 AM EDT