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ClinicalTrials.gov public records Last synced Oct 17, 2026, 3:58 AM EDT

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Showing 1–24 of 465 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Cardiopulmonary Clear all
Completed Not applicable Interventional Accepts healthy volunteers

MitoQ & Cardiopulmonary Responses During Exercise

NCT06069245
View directory record Official record
Conditions
Healthy
Interventions
MitoQ, Placebo
Dietary Supplement
Lead sponsor
Ball State University
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Muncie, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 5, 2023 · Synced Oct 17, 2026, 3:58 AM EDT
Completed Phase 2 Interventional

MEND-CABG (MC-1 to Eliminate Necrosis and Damage in Coronary Artery Bypass Graft Surgery)

NCT00157716
View directory record Official record
Conditions
Coronary Artery Bypass Graft Surgery, Myocardial Ischemia, Reperfusion Injury, Myocardial Revascularization
Interventions
(MC-1) Pyridoxal-5'-phosphate
Drug
Lead sponsor
Medicure
Industry
Eligibility
18 Years and older
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 31, 2006 · Synced Oct 17, 2026, 3:58 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Inhaled NO as an Anti-inflammatory and Anti-reperfusion Agent in Infants and Children Undergoing Cardiopulmonary Bypass

NCT00585013
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
Nitric Oxide
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Up to 16 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 4, 2015 · Synced Oct 17, 2026, 3:58 AM EDT
Completed Not applicable Interventional Results available

Balancing Risk: Red Blood Cell Transfusion Strategies In Cardiac Surgery

NCT00651573
View directory record Official record
Conditions
Anemia
Interventions
Blood transfusion at hematocrit value less than 24%, Blood transfusion at hematocrit value less than 28%
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
722 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 14, 2019 · Synced Oct 17, 2026, 3:58 AM EDT
Completed No phase listed Observational

Platelet Activation Markers in Pediatric Cardiac Surgery

NCT00450151
View directory record Official record
Conditions
Coronary Disease
Interventions
Not listed
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
Up to 7 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 1, 2012 · Synced Oct 17, 2026, 3:58 AM EDT
Terminated Phase 3 Interventional

CIS001 Extension Study of Cyclosporine Inhalation Solution

NCT00938236
View directory record Official record
Conditions
Lung Transplant
Interventions
Cyclosporine Inhalation Solution (CIS)
Drug
Lead sponsor
APT Pharmaceuticals, Inc.
Industry
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
15
States / cities
Los Angeles, California • San Francisco, California • Stanford, California + 12 more
Source: ClinicalTrials.gov public record
Updated Sep 17, 2012 · Synced Oct 17, 2026, 3:58 AM EDT
Completed No phase listed Observational

Effects of Donor and Recipient Genetic Expression on Heart, Lung, Liver, or Kidney Transplant Survival

NCT00531921
View directory record Official record
Conditions
Heart Transplantation, Kidney Transplantation, Liver Transplantation, Lung Transplantation
Interventions
Not listed
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
Up to 70 Years
Enrollment
313 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
5
States / cities
Chicago, Illinois • Ithaca, New York • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 17, 2026, 3:58 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

SHAPE Test for Preoperative Risk Stratification

NCT05743673
View directory record Official record
Conditions
Perioperative/Postoperative Complications, Aerobic Capacity
Interventions
Shape II
Device
Lead sponsor
Yale University
Other
Eligibility
60 Years and older
Enrollment
371 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Oct 17, 2026, 3:58 AM EDT
Completed Not applicable Interventional

NEURESCUE Device as an Adjunct to In-Hospital Cardiac Arrest (ARISE)

NCT05444049
View directory record Official record
Conditions
Cardiac Arrest, Cardiopulmonary Arrest, Cardiovascular Diseases
Interventions
NEURESCUE device
Device
Lead sponsor
neurescue
Industry
Eligibility
18 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Long Beach, California
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Oct 17, 2026, 3:58 AM EDT
Terminated Phase 2 Interventional

Use of Activated Recombinant Human Factor VII in Cardiac Surgery

NCT00154427
View directory record Official record
Conditions
Acquired Bleeding Disorder, Cardiac Surgery Requiring Cardiopulmonary Bypass
Interventions
activated recombinant human factor VII
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
18
States / cities
Birmingham, Alabama • Tucson, Arizona • San Francisco, California + 14 more
Source: ClinicalTrials.gov public record
Updated Jan 12, 2017 · Synced Oct 17, 2026, 3:58 AM EDT
Completed Not applicable Interventional

Impact of Immediate Point-of-Care Ultrasound on Patients With Cardiopulmonary Symptoms in the Emergency Department

NCT02861508
View directory record Official record
Conditions
Chest Pain, Dyspnea, Syncope, Hypotension
Interventions
Point-of-care ultrasound, Usual care
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 28, 2020 · Synced Oct 17, 2026, 3:58 AM EDT
Completed No phase listed Observational

Cardiopulmonary Bypass and Inflammatory Response

NCT00167349
View directory record Official record
Conditions
Thoracic Surgery, Cardiopulmonary Bypass
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 90 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 15, 2011 · Synced Oct 17, 2026, 3:58 AM EDT
Active, not recruiting Not applicable Interventional

The Feasibility of Using the PulsePoint to Facilitate Overdose Education and Naloxone Distribution

NCT06523985
View directory record Official record
Conditions
Carrying Naloxone/Narcan on Their Person or in Their Vehicle, Being Trained to Respond to an Opioid Overdose
Interventions
Push messages (standard), Push messages (customized)
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
Not listed
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 17, 2026, 3:58 AM EDT
Completed Not applicable Interventional

Goal-directed CPR Using Cerebral Oximetry

NCT04924985
View directory record Official record
Conditions
Ischemia, Reperfusion Injury
Interventions
Non-Physiological Feedback CPR, Physiological Feedback CPR
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 80 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 17, 2026, 3:58 AM EDT
Completed Not applicable Interventional

Smartphone Delivered In-home Cardiopulmonary Rehabilitation

NCT02791685
View directory record Official record
Conditions
Cardiovascular Disease, Coronary Artery Disease
Interventions
MULTIFIT Cardiac Rehabilitation, Movn Pulmonary Rehabilitation, Standard of Care Cardiac Rehabilitation
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
258 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Oct 17, 2026, 3:58 AM EDT
Recruiting No phase listed Observational

Cardiopulmonary Exercise Testing and Oscillometry for the Evaluation of Dyspnea

NCT06554353
View directory record Official record
Conditions
Breathing, Mouth, Lung Function Decreased, Dyspnea, Shortness of Breath
Interventions
Oscillometer
Device
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
50 participants
Timeline
2024 – 2026
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 17, 2026, 3:58 AM EDT
Completed Phase 3 Interventional Results available

Outcomes Following Myocardial Revascularization: On and Off Cardiopulmonary Bypass

NCT00032630
View directory record Official record
Conditions
Ischemic Heart Disease
Interventions
Coronary artery bypass - on-pump, Coronary artery bypass - off-pump
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
Not listed
Enrollment
2,203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
17
States / cities
Palo Alto, California • San Francisco, California • Sepulveda, California + 14 more
Source: ClinicalTrials.gov public record
Updated May 5, 2014 · Synced Oct 17, 2026, 3:58 AM EDT
Recruiting No phase listed Observational

Quality of Pediatric Resuscitation in a Multicenter Collaborative

NCT02708134
View directory record Official record
Conditions
Cardiac Arrest, Cardiopulmonary Arrest
Interventions
Not listed
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
0 Years to 18 Years
Enrollment
7,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2030
U.S. locations
40
States / cities
Los Angeles, California • Madera, California • Orange, California + 32 more
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Oct 17, 2026, 3:58 AM EDT
Terminated Phase 2 Interventional

Study of INS50589 Intravenous Infusion in Subjects Undergoing Coronary Artery Bypass Grafting (CABG) Involving Cardiopulmonary Bypass

NCT00316212
View directory record Official record
Conditions
Coronary Disease
Interventions
INS50589 Intravenous Infusion
Drug
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Eligibility
18 Years to 75 Years
Enrollment
160 participants
Timeline
Started 2006
U.S. locations
27
States / cities
Birmingham, Alabama • San Diego, California • Springfield, Illinois + 13 more
Source: ClinicalTrials.gov public record
Updated Nov 18, 2016 · Synced Oct 17, 2026, 3:58 AM EDT
Recruiting Not applicable Interventional

Fresh Autologous Whole Blood Transfusion After Cardiopulmonary Bypass

NCT03204357
View directory record Official record
Conditions
Cardiac Disease, Bleeding Postoperative
Interventions
Fresh Autologous whole Blood, Standard of Care Expectant management of bleeding
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 90 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Oct 17, 2026, 3:58 AM EDT
Completed Not applicable Interventional

Ketamine Pharmacokinetics in Children Having Heart Surgery

NCT00598195
View directory record Official record
Conditions
C.Surgical Procedure; Cardiac
Interventions
Ketamine
Drug
Lead sponsor
Arkansas Children's Hospital Research Institute
Other
Eligibility
1 Day to 6 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Feb 27, 2013 · Synced Oct 17, 2026, 3:58 AM EDT
Completed Not applicable Interventional

Study to Determine if Using Ventilation During Open Heart Surgery Improves Lung Outcomes

NCT01522222
View directory record Official record
Conditions
Coronary Artery Disease, Heart Failure
Interventions
continuous, mechanical ventilatory support
Procedure
Lead sponsor
Aurora BayCare Medical Center
Other
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Green Bay, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 14, 2018 · Synced Oct 17, 2026, 3:58 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Effect Of Single-Dose PF-05175157 On Metabolic And Cardiopulmonary Parameters

NCT01819922
View directory record Official record
Conditions
Healthy
Interventions
PF-05175157, Placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 40 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 2, 2016 · Synced Oct 17, 2026, 3:58 AM EDT
Completed No phase listed Observational

Aprotinin in Neonates Undergoing Cardiopulmonary Bypass

NCT00469742
View directory record Official record
Conditions
Cardiopulmonary Bypass, Congenital Defects, Hemostasis
Interventions
Not listed
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
Up to 1 Month
Enrollment
290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 16, 2012 · Synced Oct 17, 2026, 3:58 AM EDT