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ClinicalTrials.gov public records Last synced Oct 18, 2026, 1:13 AM EDT

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Showing 241–264 of 465 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Cardiopulmonary Clear all
Recruiting No phase listed Observational

Risk and Resilience in Pulmonary Arterial Hypertension and Genetically Susceptible Individuals

NCT05584722
View directory record Official record
Conditions
Idiopathic Pulmonary Arterial Hypertension, Heritable Pulmonary Arterial Hypertension, Unaffected Mutation Carriers: Healthy Participants With a Known BMPR2 Gene Mutation and Normal Pulmonary Pressure and RV Function on Echo, Healthy Individuals With no Cardiopulmonary Disease
Interventions
Not listed
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
15 Years to 80 Years
Enrollment
150 participants
Timeline
2022 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Oct 18, 2026, 1:13 AM EDT
Completed Phase 2 Interventional

Use of Ketamine Prior to Cardiopulmonary Bypass in Children

NCT00556361
View directory record Official record
Conditions
Ventricular Septal Defect
Interventions
saline, ketamine
Drug
Lead sponsor
Arkansas Children's Hospital Research Institute
Other
Eligibility
Up to 1 Year
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Nov 12, 2007 · Synced Oct 18, 2026, 1:13 AM EDT
Recruiting Not applicable Interventional

A Study of Hemodynamic Cardiopulmonary Exercise for CHD

NCT06566196
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
Cardiac Cath
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Oct 18, 2026, 1:13 AM EDT
Completed No phase listed Observational Results available

Hemosonics- VCU Cardiac Surgery Clinical Study

NCT02392247
View directory record Official record
Conditions
Cardiopulmonary Bypass
Interventions
Coagulation function
Device
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 89 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 12, 2016 · Synced Oct 18, 2026, 1:13 AM EDT
Completed Phase 3 Interventional

Dispatcher-Assisted Resuscitation Trial (DART)

NCT00219687
View directory record Official record
Conditions
Heart Arrest
Interventions
dispatcher-assisted CPR with compressions & ventilations, dispatcher-assisted CPR instructions with compressions only
Other
Lead sponsor
Public Health - Seattle and King County
Government
Eligibility
9 Years and older
Enrollment
5,494 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2012
U.S. locations
2
States / cities
Olympia, Washington • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 29, 2014 · Synced Oct 18, 2026, 1:13 AM EDT
Completed No phase listed Observational

Early Imaging Biomarkers in NSCLC

NCT03121287
View directory record Official record
Conditions
Thoracic Cancer
Interventions
Imaging Biomarkers, Pulmonary, Imaging, Specimen Collection
Other
Lead sponsor
University of Michigan Rogel Cancer Center
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 26, 2019 · Synced Oct 18, 2026, 1:13 AM EDT
Completed No phase listed Observational

Genotypes and Phenotypes in Pediatric SIRS and Sepsis

NCT02728401
View directory record Official record
Conditions
Systemic Inflammatory Response Syndrome (SIRS), Sepsis
Interventions
Not listed
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
38 Weeks to 18 Years
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 19, 2018 · Synced Oct 18, 2026, 1:13 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Nitric Oxide Administration During Pediatric Cardiopulmonary Bypass Surgery to Prevent Platelet Activation

NCT03455218
View directory record Official record
Conditions
Inflammation, Platelet Dysfunction
Interventions
Nitric Oxide, Placebo, INOmax
Drug · Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
Up to 1 Year
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 13, 2020 · Synced Oct 18, 2026, 1:13 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Cardiopulmonary Bypass-Induced Lymphocytopenia and the Potential Effects of Protease Inhibitor

NCT00385450
View directory record Official record
Conditions
Cardiopulmonary Bypass
Interventions
Nelfinavir/placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 28, 2015 · Synced Oct 18, 2026, 1:13 AM EDT
Terminated Phase 4 Interventional

Effects of IV Iron Replacement on Exercise Capacity in Individuals With Heart Failure

NCT05816265
View directory record Official record
Conditions
Heart Failure, Iron-deficiency
Interventions
IV Iron Infusion Group
Drug
Lead sponsor
Radha Gopalan
Other
Eligibility
18 Years to 90 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 18, 2026, 1:13 AM EDT
Active, not recruiting Not applicable Interventional

RACE-CARS - RAndomized Cluster Evaluation of Cardiac ARrest Systems

NCT04660526
View directory record Official record
Conditions
Cardiac Arrest
Interventions
Rapid cardiac arrest recognition that triggers immediate priority EMS/first responder dispatch by 911 operators, Systematic bystander resuscitation instruction by 911 operators, Comprehensive community training of lay people in CPR and AED use., Optimized first responder performance including earlier use of AEDs.
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
20,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 18, 2026, 1:13 AM EDT
Not listed No phase listed Observational

Gas Exchange for Predicting Hospital Heart Failure Readmissions

NCT01960218
View directory record Official record
Conditions
Acute Decompensated Heart Failure
Interventions
Not listed
Lead sponsor
Shape Medical Systems, Inc.
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
7
States / cities
Washington D.C., District of Columbia • Champaign, Illinois • Boston, Massachusetts + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 4, 2014 · Synced Oct 18, 2026, 1:13 AM EDT
Completed Phase 3 Interventional

Effect of RBT-1 on Reducing the Risk of Post-Operative Complications in Subjects Undergoing Cardiac Surgery

NCT06021457
View directory record Official record
Conditions
Post-Operative Complications in Cardiac Surgery
Interventions
RBT-1, Placebo
Drug
Lead sponsor
Renibus Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
454 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
31
States / cities
Huntsville, Alabama • La Jolla, California • San Francisco, California + 27 more
Source: ClinicalTrials.gov public record
Updated Aug 1, 2025 · Synced Oct 18, 2026, 1:13 AM EDT
Terminated Phase 1 Interventional

Antithrombin III in Infants With Cardiopulmonary Bypass (CPB)

NCT01698567
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
Antithrombin III, Placebo
Drug
Lead sponsor
University of Rochester
Other
Eligibility
1 Day to 180 Days
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Mar 22, 2016 · Synced Oct 18, 2026, 1:13 AM EDT
Completed Not applicable Interventional Results available

Delayed Rewarming for Neuroprotection in Infants Following Cardiopulmonary Bypass Surgery

NCT03036072
View directory record Official record
Conditions
Post-Op Complication
Interventions
Strict normothermia, Delayed Rewarming
Other · Device
Lead sponsor
Alexa Craig
Other
Eligibility
Up to 6 Months
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Portland, Maine
Source: ClinicalTrials.gov public record
Updated Jul 13, 2020 · Synced Oct 18, 2026, 1:13 AM EDT
Terminated Phase 4 Interventional Results available

Physiologic Effects of RBC Transfusion

NCT02566577
View directory record Official record
Conditions
Red Blood Cell Transfusion
Interventions
Fresh red blood cell (RBC) transfusion, Storage-aged red blood cell (RBC) transfusion, Electronic infusion pump
Biological · Device
Lead sponsor
Emory University
Other
Eligibility
21 Years to 80 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 24, 2019 · Synced Oct 18, 2026, 1:13 AM EDT
Withdrawn Phase 1 Interventional

Nitric Oxide During CPB to Reduce AKI in Neonates

NCT03946462
View directory record Official record
Conditions
Congenital Heart Disease, Acute Kidney Injury
Interventions
NO gas delivered during cardiac surgery, placebo gas delivered during cardiac surgery
Drug · Other
Lead sponsor
Fabio Savorgnan
Other
Eligibility
Up to 30 Days
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 1, 2021 · Synced Oct 18, 2026, 1:13 AM EDT
Completed Early Phase 1 Interventional Results available

The Effects of Modified Ultrafiltration on Vancomycin Levels During Cardiopulmonary Bypass in Cardiac Surgery

NCT02051595
View directory record Official record
Conditions
Infection
Interventions
Vancomycin concentrations
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 99 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 13, 2019 · Synced Oct 18, 2026, 1:13 AM EDT
Completed No phase listed Observational

Macrophage Inhibitory Factor and High-Mobility Group-1 Protein in Children Undergoing Cardiopulmonary Bypass

NCT00692432
View directory record Official record
Conditions
Myocardial Depression
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
Up to 5 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2008
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 10, 2017 · Synced Oct 18, 2026, 1:13 AM EDT
Completed No phase listed Observational

Diagnostic Accuracy of Doppler Resistive Indices for Early Diagnosis of Acute Kidney Injury .

NCT02580292
View directory record Official record
Conditions
Cardiac Surgical Procedures
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 12, 2024 · Synced Oct 18, 2026, 1:13 AM EDT
Withdrawn Not applicable Interventional

Study of ADI CardioPulmonary Management (CPM) System

NCT06024369
View directory record Official record
Conditions
Heart Failure
Interventions
CPM Device
Device
Lead sponsor
Analog Device, Inc.
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 16, 2024 · Synced Oct 18, 2026, 1:13 AM EDT
Completed No phase listed Observational Results available

Thromboelastography-derived Functional Fibrinogen Levels

NCT01992757
View directory record Official record
Conditions
Focus of Study, Coagulation Status of Cardiac Surgery Patient, Reducing Excess Blood Transfusion
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 3, 2018 · Synced Oct 18, 2026, 1:13 AM EDT
Completed Phase 4 Interventional Results available

An Open-Label Uncontrolled Study of the Safety and Efficacy of Ambrisentan in Participants With Exercise-Induced Pulmonary Arterial Hypertension (PAH)

NCT01338636
View directory record Official record
Conditions
Exercise-induced Pulmonary Arterial Hypertension
Interventions
Ambrisentan
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced Oct 18, 2026, 1:13 AM EDT
Completed Phase 3 Interventional

Comparing Angiomax to Heparin With Protamine in Patients Undergoing Cardiopulmonary Bypass (CPB)

NCT00079586
View directory record Official record
Conditions
Cardiovascular Disease, Coronary Artery Bypass Surgery
Interventions
Heparin, Bivalirudin
Drug
Lead sponsor
The Medicines Company
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 5, 2012 · Synced Oct 18, 2026, 1:13 AM EDT