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Showing 1–24 of 37 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cardiothoracic Surgery Clear all
Not listed Phase 4 Interventional

Evaluation of Liposomal Bupivacaine Compared to Usual Care and Its Effects on Pain for Cardiac Surgery

NCT04065919
View directory record Official record
Conditions
Cardiothoracic Surgery
Interventions
Liposomal bupivacaine, 0.25% Bupivacaine with epinephrine
Drug
Lead sponsor
Florida Heart and Lung Institute
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 5, 2020 · Synced Sep 6, 2026, 1:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Eliminate Risk of Cardiac Surgical Site Events

NCT01425697
View directory record Official record
Conditions
Surgical Site Infections
Interventions
2% Chlorhexidine Gluconate cloths, Standard of Care preoperative preparation.
Other
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
739 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
4
States / cities
Lexington, Kentucky • Ridgewood, New Jersey • Rochester, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 1, 2013 · Synced Sep 6, 2026, 1:59 PM EDT
Completed Not applicable Interventional Results available

Continuous Infusion Versus Bolus Dosing for Pain Control After Pediatric Cardiothoracic Surgery

NCT02112448
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
continuous infusion, as needed dosing, Acetaminophen, ketorolac
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
3 Months to 4 Months
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Oak Lawn, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 23, 2024 · Synced Sep 6, 2026, 1:59 PM EDT
Terminated Phase 4 Interventional

Natrecor in Pulmonary Hypertension

NCT00075179
View directory record Official record
Conditions
Pulmonary Hypertension, Cancer, Lung Disease, Cardiothoracic Surgery
Interventions
Nesiritide (Natrecor), Right Heart Catheterization
Drug · Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years to 85 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 6, 2018 · Synced Sep 6, 2026, 1:59 PM EDT
Not listed Phase 4 Interventional

Intensive Statin Therapy Effect on Post-Operative Atrial Fibrillation (POAF)

NCT02029534
View directory record Official record
Conditions
Cardiothoracic Surgery, Post-operative Atrial Fibrillation
Interventions
Atorvastatin 20 mg, Atorvastatin 80 mg
Drug
Lead sponsor
Creighton University
Other
Eligibility
19 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Jun 15, 2016 · Synced Sep 6, 2026, 1:59 PM EDT
Completed Not applicable Interventional Results available

Pilot Testing a Home-Based Rehabilitation Intervention Designed to Improve Outcomes of Frail Veterans Following Cardiothoracic Surgery

NCT03299101
View directory record Official record
Conditions
Coronary Artery Bypass Graft, Non-cardiac Thoracic Surgery, Frailty
Interventions
Prehabilitation
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 12, 2021 · Synced Sep 6, 2026, 1:59 PM EDT
Recruiting Not applicable Interventional

Virtual Reality and Olfactory Stimuli Multimodal Intervention to Reduce Post-Operative Pain and Anxiety in Patients Undergoing Cardiothoracic Surgery

NCT04912531
View directory record Official record
Conditions
Postoperative Pain, Anxiety Postoperative, Opioid Use
Interventions
Virtual Realty using a Microsoft Hololens, Empatica HR wristband, and EEG, Essence Olfactory Necklace, Bedside Olfaction Device
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Sep 6, 2026, 1:59 PM EDT
Completed No phase listed Observational

Effects of Thymectomy During Cardiothoracic Surgery

NCT00263120
View directory record Official record
Conditions
Thymectomy and Cardiothoracic Surgery
Interventions
Pain Questionnaire
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
Up to 35 Years
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 23, 2016 · Synced Sep 6, 2026, 1:59 PM EDT
Completed No phase listed Observational

Respiratory-Swallow Coordination in Cardiothoracic Surgical Patients

NCT05173207
View directory record Official record
Conditions
Thoracic Diseases, Cardiovascular Diseases
Interventions
Videofluoroscopic swallow exam with concurrent monitoring of respiratory-swallow coordination
Diagnostic Test
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 90 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 27, 2022 · Synced Sep 6, 2026, 1:59 PM EDT
Recruiting Not applicable Interventional

Robotic Exoskeletons in Acute Care Therapy

NCT07353892
View directory record Official record
Conditions
Patients Post-cardiothoracic Surgery
Interventions
Overground robotic exoskeleton early ambulation (ORE-EA), Usual care early ambulation (UC-EA)
Device · Other
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Sep 6, 2026, 1:59 PM EDT
Enrolling by invitation Not applicable Interventional

Impact of Immersive Video Education on Cardiothoracic Surgery Anxiety and Outcomes

NCT07222839
View directory record Official record
Conditions
Anxiety
Interventions
Visually Immersive Video, Standard of Care
Behavioral
Lead sponsor
Baptist Health South Florida
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Sep 6, 2026, 1:59 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Objective Assessment of Technical Skills in Cardiothoracic Surgery

NCT01433029
View directory record Official record
Conditions
Other Surgical Procedures
Interventions
Surgical Video Assessments, Video Recording of CAB
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
21 Years and older
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
6
States / cities
Dallas, Texas • Houston, Texas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 29, 2017 · Synced Sep 6, 2026, 1:59 PM EDT
Completed No phase listed Observational

BRS and Outcomes in Cardiothoracic Surgery

NCT03243279
View directory record Official record
Conditions
Pain, Postoperative, Atrial Fibrillation, Cognitive Dysfunction
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 20, 2022 · Synced Sep 6, 2026, 1:59 PM EDT
Withdrawn Not applicable Interventional

Preoperative Self-managed Respiratory Therapy for Reduction of Postoperative Pulmonary Complications

NCT03356496
View directory record Official record
Conditions
Postoperative Respiratory Complication
Interventions
AirLife 4000 cc incentive spirometry device
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 28, 2022 · Synced Sep 6, 2026, 1:59 PM EDT
Completed Not applicable Interventional

Fortified Skimmed Mother's Milk in the Management of Chylothorax

NCT01673165
View directory record Official record
Conditions
Chylous Pleural Effusion Following Cardiothoracic Surgery
Interventions
Skimmed mother's milk, Specialized Formula
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
1 Day to 12 Months
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 13, 2015 · Synced Sep 6, 2026, 1:59 PM EDT
Recruiting No phase listed Observational

Factors Affect Outcomes in Cardiovascular Surgery

NCT01932411
View directory record Official record
Conditions
Coronary Artery Disease, Valvular Diseases, Vascular Diseases
Interventions
Not listed
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2026
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Sep 6, 2026, 1:59 PM EDT
Not listed Not applicable Interventional

Regional Anesthesia for Cardiothoracic Enhanced Recovery

NCT03781440
View directory record Official record
Conditions
Opioid Use, Anesthesia, Local, Cardiac Disease, Pain, Acute
Interventions
Bilateral ESP catheter with lidocaine, Bilateral ESP catheter with saline
Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Sep 21, 2023 · Synced Sep 6, 2026, 1:59 PM EDT
Recruiting No phase listed Observational

A Multicenter Patient Registry on Outcomes From Cryoanalgesia of the Intercostal Nerves

NCT05110989
View directory record Official record
Conditions
Post Operative Pain
Interventions
AtriCure Cryo Nerve Block (cryoNB) Device Family
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
12 Years and older
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2040
U.S. locations
7
States / cities
Jacksonville, Florida • Orlando, Florida • Annapolis, Maryland + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Sep 6, 2026, 1:59 PM EDT
Recruiting Not applicable Interventional

Groundbreaking Renal Assist Device Intervening to ENhance cardioThoracic Surgery Outcomes

NCT07017933
View directory record Official record
Conditions
Renal Impairment After Cardiac Surgery, Renal Impairment, Acute Kidney Injury
Interventions
Renal assist device
Device
Lead sponsor
3ive Labs
Industry
Eligibility
22 Years to 85 Years
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
4
States / cities
Weston, Florida • Ann Arbor, Michigan • Chapel Hill, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Sep 6, 2026, 1:59 PM EDT
Completed Not applicable Interventional Results available

Effectiveness and Safety of CELSTAT for Hemostasis in Intraoperative Tissue Bleeding

NCT02640235
View directory record Official record
Conditions
Bleeding Active
Interventions
CELSTAT, Surgicel Original
Device
Lead sponsor
Baxter Healthcare Corporation
Industry
Eligibility
18 Years and older
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
19
States / cities
Washington D.C., District of Columbia • Gainesville, Florida • Jacksonville, Florida + 14 more
Source: ClinicalTrials.gov public record
Updated Aug 2, 2020 · Synced Sep 6, 2026, 1:59 PM EDT
Completed No phase listed Observational

Identification of Dominate Stressors in the Intensive Care Unit (ICU)

NCT00645008
View directory record Official record
Conditions
Cardiac Surgery Intensive Care Treatment
Interventions
Not listed
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 99 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 5, 2017 · Synced Sep 6, 2026, 1:59 PM EDT
Completed Phase 4 Interventional

Impact of Ascorbic Acid on Post-Cardiothoracic Surgery Inflammation

NCT00519337
View directory record Official record
Conditions
Cardiac Surgery, Inflammation
Interventions
Ascorbic acid, Placebo
Drug
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 4, 2012 · Synced Sep 6, 2026, 1:59 PM EDT
Completed Not applicable Interventional Results available

HEMOBLAST Pivotal Clinical Investigation

NCT02780869
View directory record Official record
Conditions
Hemostasis
Interventions
HEMOBLAST Bellows, Absorbable gelatin sponge, USP with thrombin
Device
Lead sponsor
Biom'Up France SAS
Industry
Eligibility
21 Years and older
Enrollment
258 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
17
States / cities
Phoenix, Arizona • Los Angeles, California • Pasadena, California + 12 more
Source: ClinicalTrials.gov public record
Updated Dec 26, 2018 · Synced Sep 6, 2026, 1:59 PM EDT
Completed No phase listed Observational Results available

A Study to Evaluate ICU Simulation Experience in the Cardiothoracic Surgical Population to Reduce Post-operative Delirium

NCT05159648
View directory record Official record
Conditions
Post-Operative Delirium
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 60 Years
Enrollment
234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 7, 2025 · Synced Sep 6, 2026, 1:59 PM EDT