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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cardiovascular Disease Risk Reduction Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of Clinic-delivered Physical Activity Referrals to Cancer Survivors

NCT05216380
View directory record Official record
Conditions
Cancer, Physical Inactivity
Interventions
ActivityLink
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years to 100 Years
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 22, 2024 · Synced Jun 10, 2026, 8:34 PM EDT
Terminated Phase 2 Interventional Results available

UARK 2012-02 Trial For High-Risk Myeloma Evaluating Accelerating and Sustaining Complete Remission

NCT02128230
View directory record Official record
Conditions
Multiple Myeloma
Interventions
myPRS, Induction 1 - MEL-10+CFZ-TD-PACE, First Transplant - MEL-80+CFZ-TD-PACE + PBSC (biologic), Inter-Therapy - MEL-20+CFZ-TD-PACE (75%), Second Transplant - MEL-80+CFZ-TD-PACE + PBSC (biologic), Consolidation - CFZ-TD-PACE, Maintenance - CFZ-R(T)-D
Device · Drug
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jun 21, 2021 · Synced Jun 10, 2026, 8:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Strategies for Inflammation and Cardiovascular Disease (CVD) Prevention

NCT02165228
View directory record Official record
Conditions
Atherosclerosis, Diabetes
Interventions
Mindfulness-based stress reduction, Nutrition Enhancement
Behavioral
Lead sponsor
Montana State University
Other
Eligibility
25 Years to 55 Years
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Bozeman, Montana
Source: ClinicalTrials.gov public record
Updated Jun 16, 2014 · Synced Jun 10, 2026, 8:34 PM EDT
Terminated Phase 1 Interventional

Evaluate Use of Mangosteen Juice Added to Usual Care in Reducing Risk of Recurrent Atrial Fibrillation

NCT00951301
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
mangosteen juice, placebo juice
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
143 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 15, 2016 · Synced Jun 10, 2026, 8:34 PM EDT
Recruiting Phase 2 Interventional

GLP-1 Receptor Agonists to Decrease Ethanol and CVD Risk in HIV

NCT07221214
View directory record Official record
Conditions
HIV, Alcohol, Smoking Cigarette, Cardiovascular Disease Prevention
Interventions
Semaglutide (Rybelsus®), Placebo
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Jun 10, 2026, 8:34 PM EDT
Recruiting Phase 3 Interventional

NO During CPB in Neonates to Reduce Risk of AKI

NCT04216927
View directory record Official record
Conditions
AKI, CHD - Congenital Heart Disease, Surgery
Interventions
Nitric Oxide, Oxygen
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
1 Day to 31 Days
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 23, 2025 · Synced Jun 10, 2026, 8:34 PM EDT
Completed Not applicable Interventional Results available

Diabetes Prevention Translation: the Healthy Lifestyle Project

NCT01050205
View directory record Official record
Conditions
Diabetes, Cardiovascular Risk Factor
Interventions
Current Intervention, Delayed Intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
223 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 24, 2017 · Synced Jun 10, 2026, 8:34 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

The Health for Hearts United Collaborative

NCT05259150
View directory record Official record
Conditions
Cardiovascular Disease Risk Reduction
Interventions
Health for Hearts United Planning for Health, Health for Hearts United Preparing for Health, Health for Hearts United Delivery of Health, Health for Hearts United Comparison Group Health Ministry Development
Behavioral · Other
Lead sponsor
Florida State University
Other
Eligibility
18 Years and older
Enrollment
225 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Jun 10, 2026, 8:34 PM EDT
Enrolling by invitation Not applicable Interventional

Actions to Decrease Disparities in Risk and Engage in Shared Support for Blood Pressure Control (ADDRESS-BP) in Blacks

NCT05208450
View directory record Official record
Conditions
Hypertension (HTN)
Interventions
Practice support And Community Engagement (PACE)
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Jun 10, 2026, 8:34 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Healthy Heart Habits

NCT04158219
View directory record Official record
Conditions
Acute Coronary Syndrome, Depression
Interventions
Behavioral activation for health and depression (BA-HD)
Behavioral
Lead sponsor
Hennepin Healthcare Research Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 9, 2022 · Synced Jun 10, 2026, 8:34 PM EDT
Recruiting Not applicable Interventional

Reducing the Risk of Chronic Hypertension and Improving Vascular Function Following Preeclampsia

NCT06220721
View directory record Official record
Conditions
Hypertension, Pregnancy-Induced
Interventions
Nifedipine ER
Drug
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older · Female only
Enrollment
618 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
2
States / cities
Chicago, Illinois • Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 10, 2025 · Synced Jun 10, 2026, 8:34 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Investigating Cardiac Health of Adults With Trauma

NCT05700201
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Lifestyle / Healthy Behavior Intervention, standard care
Behavioral · Other
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years and older
Enrollment
216 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Source: ClinicalTrials.gov public record
Updated Jul 28, 2025 · Synced Jun 10, 2026, 8:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Giving a Low Carbohydrate Diet to Overcome Hypertension

NCT04230928
View directory record Official record
Conditions
Hypertension, African Americans, Diet, Carbohydrate-Restricted, Risk Reduction Behavior
Interventions
Very low carbohydrate diet, Standard DPP-GLB diet, Standard DPP-GLB program modules
Other · Behavioral
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 74 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 1, 2026 · Synced Jun 10, 2026, 8:34 PM EDT
Completed Not applicable Interventional

Cleaner Air for Lower Cardiometabolic Risk

NCT05994937
View directory record Official record
Conditions
PreDiabetes
Interventions
PAC with HEPA filter intact, PAC with HEPA filter removed
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 85 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Jun 10, 2026, 8:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Reducing Cardiovascular Disease Risk in Perimenopausal Latinas

NCT04313751
View directory record Official record
Conditions
Cardiovascular Risk Factor, Health Behavior, Physical Activity, Self Efficacy, Vascular Stiffness
Interventions
Education, Physical Activity, and Stress Management Program, Wait-list
Behavioral · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
40 Years to 60 Years · Female only
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 19, 2024 · Synced Jun 10, 2026, 8:34 PM EDT
Active, not recruiting Phase 3 Interventional

Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) Cardiovascular Outcomes Study (MK-0616-015) CORALreef Outcomes

NCT06008756
View directory record Official record
Conditions
Arteriosclerosis, Hypercholesterolaemia
Interventions
Enlicitide Decanoate, Placebo
Drug
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Eligibility
18 Years and older
Enrollment
14,550 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2031
U.S. locations
132
States / cities
Alexander City, Alabama • Birmingham, Alabama • Daphne, Alabama + 113 more
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Jun 10, 2026, 8:34 PM EDT
Active, not recruiting Not applicable Interventional

Healthy Heart Habits-2

NCT06440278
View directory record Official record
Conditions
Acute Coronary Syndrome
Interventions
Behavioral Activation for Health and Depression (BA-HD), Enhanced Usual Care
Behavioral · Other
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
3
States / cities
Minneapolis, Minnesota • Greenville, North Carolina • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Jun 10, 2026, 8:34 PM EDT
Recruiting Not applicable Interventional

Reducing Blood Pressure in Patients With High Cardiovascular Risk

NCT05937685
View directory record Official record
Conditions
Myocardial Infarction, Hypertension, Stroke
Interventions
BP REACH Intervention
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
35 Years and older
Enrollment
546 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
4
States / cities
Downey, California • Los Angeles, California • Sylmar, California + 1 more
Source: ClinicalTrials.gov public record
Updated May 13, 2025 · Synced Jun 10, 2026, 8:34 PM EDT
Not listed Not applicable Interventional

Comparison of Three Balance Training Protocols for Individuals Post Stroke

NCT03757026
View directory record Official record
Conditions
Fall, Risk Reduction, Stroke, Balance
Interventions
Conventional Physical Therapy, Slip Training, Harnessed gaming
Other
Lead sponsor
Cleveland State University
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 22, 2019 · Synced Jun 10, 2026, 8:34 PM EDT
Completed Phase 3 Interventional Results available

A Study of AMR101 to Evaluate Its Ability to Reduce Cardiovascular Events in High-Risk Patients With Hypertriglyceridemia and on Statin

NCT01492361
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
AMR101, Placebo, Statin therapy
Drug
Lead sponsor
Amarin Pharma Inc.
Industry
Eligibility
45 Years and older
Enrollment
8,179 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
176
States / cities
Birmingham, Alabama • Huntsville, Alabama • Mobile, Alabama + 154 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2022 · Synced Jun 10, 2026, 8:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Minority Health Through Biofeedback and Stress Reduction

NCT07172152
View directory record Official record
Conditions
Cardiovascular Disease Risk Reduction, Chronic Stress, Anxiety, Emotional Regulation, Hypertension Prevention, Health Disparities
Interventions
HRV Biofeedback Training
Behavioral
Lead sponsor
Amelia Saul, PhD, CTRS, BCB
Other
Eligibility
18 Years to 35 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Jun 10, 2026, 8:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Heart of the Family: A Cardiovascular Disease and Type 2 Diabetes Risk Reduction Intervention in High-Risk Rural Families

NCT04891575
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Cardiovascular Diseases
Interventions
Active Control Intervention educational sessions, Family Dyad Intervention
Behavioral
Lead sponsor
Gia Mudd
Other
Eligibility
18 Years and older
Enrollment
504 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 8, 2026 · Synced Jun 10, 2026, 8:34 PM EDT
Completed Not applicable Interventional

Automated Guidance Tool for Medical Encounters Addressing Therapeutic Lifestyle Changes (AuGMEnT).

NCT00790491
View directory record Official record
Conditions
Heart Disease, Diabetes
Interventions
guidance tool for providers for lifestyle changes
Behavioral
Lead sponsor
Griffin Hospital
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Waterbury, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 6, 2013 · Synced Jun 10, 2026, 8:34 PM EDT
Completed Not applicable Interventional Results available

Postpartum Weight Loss for Women at Elevated Cardiovascular Risk

NCT04914819
View directory record Official record
Conditions
Weight Loss, Postpartum Weight Retention, Hypertension in Pregnancy, Diabetes Mellitus in Pregnancy, Preeclampsia, Recruitment
Interventions
Online Behavioral Weight Loss Program, Virtual weigh-in
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older · Female only
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 5, 2023 · Synced Jun 10, 2026, 8:34 PM EDT