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ClinicalTrials.gov public records Last synced Oct 6, 2026, 10:14 AM EDT

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Showing 25–48 of 99 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Cardiovascular Diseases in Old Age Clear all
Completed Not applicable Interventional

Responders to Rhythmic Auditory Stimulation in Individuals Post-Stroke and Older Adults

NCT06085248
View directory record Official record
Conditions
Stroke, Old Age
Interventions
Subject-specific optimized RAS, Active walking
Other · Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years to 80 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 6, 2026, 10:14 AM EDT
Completed Not applicable Interventional

Geriatric Optimization Plan to Improve Survival in Older Adult Allogeneic Hematopoietic Cell Transplant Candidates, OTIS Study

NCT05972577
View directory record Official record
Conditions
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Aplastic Anemia, Chronic Lymphocytic Leukemia, Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Hematopoietic and Lymphoid Cell Neoplasm, Hodgkin Lymphoma, Myelodysplastic Syndrome, Myelofibrosis, Myeloproliferative Neoplasm, Non-Hodgkin Lymphoma, Plasma Cell Myeloma
Interventions
Health Promotion and Education, Medical Device Usage and Evaluation, Quality-of-Life Assessment, Questionnaire Administration
Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
60 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Oct 6, 2026, 10:14 AM EDT
Not listed Not applicable Interventional

Improving Geriatric Drug Safety in Underserved Practices

NCT00277173
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
Adoption of Crew Resource Management approach
Behavioral
Lead sponsor
Agency for Healthcare Research and Quality (AHRQ)
Federal
Eligibility
65 Years and older
Enrollment
4,800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2006
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jan 16, 2006 · Synced Oct 6, 2026, 10:14 AM EDT
Completed Phase 1 Interventional Results available

Comparison of Prasugrel and Clopidogrel in Very Elderly and Non-Elderly Patients With Stable Coronary Artery Disease

NCT01107912
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
prasugrel, clopidogrel
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
45 Years and older
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
3
States / cities
Jacksonville, Florida • Baltimore, Maryland • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 26, 2012 · Synced Oct 6, 2026, 10:14 AM EDT
Completed Phase 2 Interventional

Mechanisms and Therapeutic Effects of the Relaxation Response in Elderly Hypertensive Patients

NCT00179543
View directory record Official record
Conditions
Hypertension
Interventions
Relaxation response
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
55 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2001
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 19, 2006 · Synced Oct 6, 2026, 10:14 AM EDT
Completed Not applicable Interventional

Exercise Prescription for the Improvement of Quality of Life in Elderly Patients With Multiple Myeloma

NCT04100044
View directory record Official record
Conditions
Plasma Cell Myeloma
Interventions
Exercise Counseling, Exercise Intervention, Questionnaire administration, Quality-of-Life Assessment
Other · Behavioral
Lead sponsor
Thomas Jefferson University
Other
Eligibility
65 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 29, 2025 · Synced Oct 6, 2026, 10:14 AM EDT
Completed Phase 1 Interventional

Mechanisms of the Relaxation Response in Elderly Hypertensives

NCT00913991
View directory record Official record
Conditions
Hypertension
Interventions
Stress Management Training
Behavioral
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
55 Years to 100 Years
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 11, 2019 · Synced Oct 6, 2026, 10:14 AM EDT
Withdrawn Not applicable Interventional

Pathways to Improving Functional Capacity in Older Patients With Chronic Kidney Disease and Cardiovascular Disease

NCT02473705
View directory record Official record
Conditions
Chronic Kidney Disease, Cardiovascular Disease
Interventions
Fish Oil and Bicarbonate, Fish Oil and Bicarbonate Placebo, Fish Oil Placebo and Bicarbonate, Fish Oil Placebo and Bicarbonate Placebo
Dietary Supplement
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
60 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 7, 2017 · Synced Oct 6, 2026, 10:14 AM EDT
Withdrawn Phase 3 Interventional

Does Administration of Etomidate and Propofol of the Anesthetic Induction of Elderly Hypertensive Patient Provide Superior Blood Pressure Stability in Response to Direct Laryngoscopy When Compared to Propofol or Etomidate Alone?

NCT01248234
View directory record Official record
Conditions
Hypertension
Interventions
propofol, Etomidate, Propofol and Etomidate
Drug
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
65 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Jul 16, 2012 · Synced Oct 6, 2026, 10:14 AM EDT
Terminated Phase 2 Interventional Results available

A Study of the Effects of CY6463 in Participants With Alzheimer's Disease With Vascular Pathology

NCT04798989
View directory record Official record
Conditions
Alzheimer's Disease With Vascular Pathology
Interventions
CY6463, Placebo
Drug
Lead sponsor
Tisento Therapeutics
Industry
Eligibility
60 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
5
States / cities
Scottsdale, Arizona • Miami, Florida • Honolulu, Hawaii + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 30, 2024 · Synced Oct 6, 2026, 10:14 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Off-pump Versus On-pump Coronary Artery Bypass Grafting in Frail Patients

NCT02338947
View directory record Official record
Conditions
Frail Elderly, Coronary Artery Disease
Interventions
Off-pump coronary-artery bypass grafting, On-pump coronary-artery bypass grafting
Other
Lead sponsor
University of Sao Paulo General Hospital
Other
Eligibility
60 Years and older
Enrollment
440 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 5, 2025 · Synced Oct 6, 2026, 10:14 AM EDT
Completed Phase 3 Interventional

PANDORA: Delirium Prevention After Cardiac Surgery Using IV Acetaminophen to Prevent Postoperative Delirium in Older Cardiac Surgical Patients

NCT04093219
View directory record Official record
Conditions
Delirium in Old Age, Delirium, Coronary Artery Disease
Interventions
IV acetaminophen, Placebo
Drug · Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
60 Years and older
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
10
States / cities
Birmingham, Alabama • Irvine, California • Los Angeles, California + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 6, 2026, 10:14 AM EDT
Completed Phase 2 Interventional Results available

Study of the Safety and Efficacy of LCZ696 on Arterial Stiffness in Elderly Patients With Hypertension

NCT01692301
View directory record Official record
Conditions
Hypertension
Interventions
LCZ696, Olmesartan, LCZ696 matching placebo, Olmesartan matching placebo, amlodipine, hydrochlorothiazide
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
60 Years and older
Enrollment
454 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
11
States / cities
Clearwater, Florida • Chicago, Illinois • Baltimore, Maryland + 8 more
Source: ClinicalTrials.gov public record
Updated May 4, 2016 · Synced Oct 6, 2026, 10:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy Long-term Dietary Nitrate Consumption to Plasma Nitrite Conversion

NCT05380167
View directory record Official record
Conditions
Cardiovascular Diseases in Old Age
Interventions
BRJ Nitrate, BRJ Placebo
Dietary Supplement
Lead sponsor
Wake Forest University
Other
Eligibility
40 Years to 80 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 25, 2022 · Synced Oct 6, 2026, 10:14 AM EDT
Completed Not applicable Interventional Results available

Exercise Intolerance in Elderly Patients With Diastolic Heart Failure

NCT00959660
View directory record Official record
Conditions
Heart Failure, Diastolic, Obesity
Interventions
Exercise, Dietary Intervention, Diet and exercise, Attention Control
Behavioral · Dietary Supplement · Other
Lead sponsor
Wake Forest University
Other
Eligibility
60 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 15, 2019 · Synced Oct 6, 2026, 10:14 AM EDT
Completed Not applicable Interventional Results available

Geriatric-assessment Interventions to Address Functional Deficits in Older Adults w Multiple Myeloma

NCT04999085
View directory record Official record
Conditions
Multiple Myeloma, Myeloma, Disability Physical, Disabilities Multiple
Interventions
Supportive care interventions
Other
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
60 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 28, 2025 · Synced Oct 6, 2026, 10:14 AM EDT
Completed Phase 3 Interventional Results available

Efficacy and Safety of Brimonidine Tartrate Ophthalmic Solution in Adult and Geriatric Participants With Ocular Redness

NCT01959230
View directory record Official record
Conditions
Hyperemia
Interventions
Brimonidine Tartrate, Vehicle, Sodium Fluorescein, Fluorescein Sodium and Benoximate Hydrocholoride Ophthalmic Solution USP
Drug
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 23, 2019 · Synced Oct 6, 2026, 10:14 AM EDT
Completed No phase listed Observational

Evaluation of Comprehensive Geriatric Assessment and Laboratory Biomarkers in Elderly Patients With Multiple Myeloma

NCT05918185
View directory record Official record
Conditions
Plasma Cell Myeloma
Interventions
Biospecimen Collection, Comprehensive Geriatric Assessment, Electronic Health Record Review, Survey Administration
Procedure · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
65 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 6, 2026, 10:14 AM EDT
Completed No phase listed Observational

Yield and Safety of Colonoscopy in Patients Older Than 80 Years

NCT00590434
View directory record Official record
Conditions
Colorectal Neoplasms
Interventions
Not listed
Lead sponsor
Midwest Biomedical Research
Other
Eligibility
18 Years and older
Enrollment
169 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 26, 2012 · Synced Oct 6, 2026, 10:14 AM EDT
Not listed Not applicable Interventional

Effect of a Community-based Nursing Intervention on Mortality in Chronically Ill Older Adults

NCT01071967
View directory record Official record
Conditions
Heart Failure, Coronary Disease, Diabetes Mellitus, Asthma, Hypertension, Hypercholesterolemia
Interventions
Community-based nurse care management
Other
Lead sponsor
Health Quality Partners
Other
Eligibility
65 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2016
U.S. locations
1
States / cities
Doylestown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 10, 2013 · Synced Oct 6, 2026, 10:14 AM EDT
Recruiting Not applicable Interventional

Hybrid Group Singing

NCT07355192
View directory record Official record
Conditions
Coronary Artery Disease, Elderly
Interventions
group singing (hybrid format), instructional sing-along video series
Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
55 Years to 89 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 6, 2026, 10:14 AM EDT
Completed Phase 2 Interventional

The DIAMOND Study: Distensibility Improvement And Remodeling in Diastolic Heart Failure

NCT00043836
View directory record Official record
Conditions
Heart Failure, Congestive, Dyspnea, Pulmonary Edema
Interventions
ALT-711
Drug
Lead sponsor
Synvista Therapeutics, Inc
Industry
Eligibility
60 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
2
States / cities
Winston-Salem, North Carolina • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 2, 2009 · Synced Oct 6, 2026, 10:14 AM EDT
Not listed No phase listed Observational

Evaluation of Home-based Sensor System to Detect Health Decompensation in Elderly Patients With History of CHF or COPD

NCT05865184
View directory record Official record
Conditions
COPD, Chronic Obstructive Pulmonary Disease, COPD Exacerbation, CHF, Congestive Heart Failure
Interventions
Data collection
Other
Lead sponsor
Sensorum Health Inc.
Industry
Eligibility
65 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Neptune City, New Jersey
Source: ClinicalTrials.gov public record
Updated May 18, 2023 · Synced Oct 6, 2026, 10:14 AM EDT
Completed Phase 4 Interventional Results available

An Examination of the Blood Pressure Lowering Ability and Safety of Olmesartan Medoxomil in Elderly Patients With Hypertension

NCT00412932
View directory record Official record
Conditions
Hypertension
Interventions
Olmesartan medoxomil, Olmesartan medoxomil/hydrochlorothiazide
Drug
Lead sponsor
Daiichi Sankyo
Industry
Eligibility
65 Years and older
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
29
States / cities
Birmingham, Alabama • Mesa, Arizona • Long Beach, California + 26 more
Source: ClinicalTrials.gov public record
Updated Sep 22, 2009 · Synced Oct 6, 2026, 10:14 AM EDT