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ClinicalTrials.gov public records Last synced Nov 5, 2026, 6:12 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 217–240 of 1,407 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Cardiovascular Function Clear all

Conditions: HIV Infection, Pulmonary Hypertension, Endothelial Function, HIV Infections
Interventions: Not listed
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 365 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2021
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Ischemic Stroke
Interventions: TF0023; Drug
Lead sponsor: Techfields Inc; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 225 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2024
U.S. locations: 24
States / cities: Scottsdale, Arizona • Colorado Springs, Colorado • Englewood, Colorado + 19 more

Conditions: Single-ventricle
Interventions: Spironolactone; Drug
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 1 Year to 6 Years
Enrollment: 98 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Stroke, Myocardial Infarctions
Interventions: Clopidogrel, Aspirin 81 mg, Aspirin >300 mg; Drug
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 93 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Peripheral Arterial Disease, Critical Limb Ischemia
Interventions: BOLD-MRI; Other
Lead sponsor: Zimmer Biomet; Industry
Eligibility: 19 Years to 89 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016
U.S. locations: 1
States / cities: Springfield, Illinois

Conditions: Brain Injuries, Acute, Brain Injuries, Traumatic, Brain Ischemia, Brain Hypoxia, Hypoxia-Ischemia, Brain, Heart Arrest, Stroke, Intracranial Hemorrhages, Coma, Persistent Vegetative State
Interventions: Phenobarbital Sodium Injection, Levetiracetam, Lacosamide Injectable Product, Valproate Sodium, Fosphenytoin; Drug
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Months to 70 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Stroke
Interventions: Propulsion Neuroprosthesis; Device
Lead sponsor: Boston University Charles River Campus; Other
Eligibility: 18 Years to 80 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 2
States / cities: Boston, Massachusetts

Conditions: Stroke, Hemiparesis
Interventions: MAHI EXO-II exoskeleton augmented with BMI system; Device
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years to 75 Years
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2018
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Cardiovascular Diseases, Heart Diseases, Coronary Disease
Interventions: Angiotensin-Converting Enzyme Inhibitors, Coronary Artery Bypass Graft, Angiotensin Receptor Blockers, Spironolactone, Aspirin, Clopidogrel, Surgical Ventricular Restoration; Drug · Procedure
Lead sponsor: Baylor Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2007
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Stroke, Healthy
Interventions: Assisted Motion with Enhanced Sensation training; Device
Lead sponsor: Shirley Ryan AbilityLab; Other
Eligibility: 18 Years to 70 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Heart Disease (Coronary Artery Disease, Ischemic Heart Disease, Hypertensive Heart Disease), Uncontrolled Diabetes (HBA1c ≥ 10)
Interventions: IPROACTIF (Integrated PRimary Care and Occupational Therapy for Aging and Chronic Disease Treatment to preserve Independence and Functioning), Usual primary care services; Other
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 55 Years and older
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Peripheral Arterial Disease
Interventions: L-N^G monomethyl arginine (L-NMMA); Drug
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Cardiovascular Diseases, Atherosclerosis, Myocardial Infarction
Interventions: Aspirin; Drug
Lead sponsor: Florida Atlantic University; Other
Eligibility: 40 Years to 80 Years
Enrollment: 37 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2009
U.S. locations: 2
States / cities: Atlantis, Florida • Tamarac, Florida

Conditions: Elevated Blood Pressure, Hypertension
Interventions: Boxing Training, Control flexibility; Other
Lead sponsor: University of Texas, El Paso; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020
U.S. locations: 1
States / cities: El Paso, Texas

Conditions: Obesity & Overweight, Perimenopausal Women, Prebiotics, Inulin, Muscle, Skeletal, Cardiovascular Diseases (CVD), Microbiota, Gastrointestinal Microbiome, Dietary Fiber, Women Health, Vascular Health, Insulin Resistance
Interventions: Inulin, Maltodextrin (Placebo); Dietary Supplement
Lead sponsor: George Washington University; Other
Eligibility: 40 Years to 55 Years · Female only
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Cigarette Smoking Toxicity, Nicotine, Acute Cardiovascular Disease
Interventions: Prazosin; Drug
Lead sponsor: University of Louisville; Other
Eligibility: 18 Years to 40 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018
U.S. locations: 1
States / cities: Louisville, Kentucky

Conditions: Bariatric Surgery
Interventions: GLP-1; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 21 Years to 65 Years
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Heart Failure, Cardiac Failure, Congestive Heart Failure, Insomnia, Sleep Disorder, Sleep Initiation and Maintenance Disorders, Disorders of Initiating and Maintaining Sleep, Anxiety, Depression
Interventions: Brief treatment for Insomnia, Sleep Monitoring; Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 76 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Rheumatoid Arthritis
Interventions: TNF inhibitors, DMARDs; Drug
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 149 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Elevated Blood Pressure, Endothelial Dysfunction
Interventions: 2,000 International Units (IU)of vitamin D3; Dietary Supplement
Lead sponsor: Texas Woman's University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 27 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Cardiovascular Injury, Prostate Carcinoma
Interventions: Magnetic Resonance Imaging, Exercise Intervention, Perfusion Magnetic Resonance Imaging, Spectroscopy, Laboratory Biomarker Analysis; Procedure · Behavioral · Other
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: Male only
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2026
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Stroke, Spinal Cord Injuries
Interventions: Rehabilitation using motorized glove for stroke and spinal cord injury, Functional MRI for stroke and spinal cord injury, Transcranial magnetic stimulation (TMS) for stroke and spinal cord injury; Other
Lead sponsor: VA Pittsburgh Healthcare System; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: TBI (Traumatic Brain Injury), Status Epilepticus, Bacterial Meningitis, Augmented Renal Clearance (ARC), Subarachnoid Hemorrhage, Aneurysmal, Ischemic Stroke, Intracerebral Hemorrhage
Interventions: Not listed
Lead sponsor: University of Alberta; Other
Eligibility: 18 Years to 85 Years
Enrollment: 512 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 2
States / cities: Lexington, Kentucky • Columbus, Ohio

Conditions: Cardiovascular Diseases
Interventions: Nutrition, Exercise, Stress Management Counseling, usual care; Behavioral · Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 45 Years to 75 Years
Enrollment: 2,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2029
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Search by objective public record fields.

Epidemiology and Pathogenesis of HIV-Associated Pulmonary Hypertension

A Study to Evaluate the Efficacy and Safety of TF0023 Spray on Subjects With Ischemic Strokes

Fibrosis and the Fontan

Aspirin Resistance and Stroke Risk: Platelet Function Analysis in Patients With Ischemic Events

BOLD MRI as a Surrogate of Improved Muscle Oxygenation Following Endovascular Therapy for the Treatment of CLI

Antiseizure Medication in Seizure Networks at Early Acute Brain Injury

Effects of an Overground Propulsion Neuroprosthesis in Community-dwelling Individuals After Stroke

Brain Machine Interface Control of an Robotic Exoskeleton in Training Upper Extremity Functions in Stroke

Impact of Medical and Surgical Therapy on Functional Mitral Regurgitation

Effects of Vibration on Motor Function of Survivors of Chronic Stroke

Piloting the IPROACTIF Program to Preserve Functioning and Prevent Cognitive Decline

Endothelial Function in Lower Extremity Bypass Grafts

Aspirin Dose and Atherosclerosis in Patients With Heart Disease

Clinical Effectiveness of Boxing Training in Individuals With Elevated Blood Pressure or Stage 1 Hypertension

Prebiotic Inulin for Late-Reproductive Individuals

The Acute Cardiovascular Effects of Nicotine in E-cigarettes (ACE) Study

The Effect of Surgically Induced Weight Loss on Endocrine Function, Cardiovascular Function and Body Composition

Heart Failure Insomnia Treatment Study

RHYTHM (Formerly Escape II Myocardium)

Effectiveness of Vitamin D Supplementation

Cardiac MRI in Measuring the Impact of Anti-androgen Treatment on Cardiac Function in Patients With Prostate Cancer

Cortical Biomarkers of Hand Function and Recovery After Injury

Augmented Renal Clearance in Neurocritical Care

Novel Strategies for Reducing Heart Disease Risk Disparities