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ClinicalTrials.gov public records Last synced Nov 6, 2026, 4:58 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 529–552 of 1,410 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Cardiovascular Function Clear all

Conditions: Coronary Artery Disease, Mitral Valve Insufficiency, Aortic Valve Stenosis, Aortic Valve Regurgitation, Mitral Valve Stenosis, Coronary Artery Bypass Graft Triple Vessel
Interventions: Ambulation orderly; Procedure
Lead sponsor: Baystate Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Springfield, Massachusetts

Conditions: Pre-hypertension, JNC 7 Stage I Hypertension
Interventions: Allopurinol, Placebo; Drug
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years to 40 Years
Enrollment: 99 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Heart Failure, Decompensated Heart Failure
Interventions: Not listed
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2022
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Heart Failure, Systolic, Heart Failure With Preserved Ejection Fraction
Interventions: Virtual Visit; Other
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older
Enrollment: 94 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Estrogen Deficiency, Cardiovascular Disease (CVD), Functional Hypothalamic Amenorrhea, Endothelial Dysfunction
Interventions: 17beta Estradiol, Transdermal placebo patch, Progesterone, Placebo Pill; Drug
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 18 Years to 60 Years · Female only
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Spinal Cord Injuries, Cardiovascular Abnormalities, Cerebrovascular Disease; Sequelae, Cognitive Impairment
Interventions: One bout of moderate-intensity sub-maximal aerobic exercise; Behavioral
Lead sponsor: State University of New York at Buffalo; Other
Eligibility: 18 Years to 55 Years
Enrollment: 6 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Cardiopulmonary Disease
Interventions: Not listed
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 592 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2020
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Coronary Artery Disease, Atherosclerosis, Inflammation, Endothelial Dysfunction
Interventions: Rilonacept, Placebo; Drug
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Intermittent Claudication, Peripheral Vascular Diseases
Interventions: Treadmill Exercise Training, Arm Ergometry Exercise Training, Usual Care; Behavioral
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years to 90 Years
Enrollment: 104 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Healthy
Interventions: Estradiol followed by progesterone, Raloxifene; Drug
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2006
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Spinal Cord Injury
Interventions: Natesto testosterone intranasal gel, Ayr Saline Nasal Gel; Drug
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 80 Years · Male only
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Thrombosis
Interventions: BMS-986177; Drug
Lead sponsor: Bristol-Myers Squibb; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 3
States / cities: Miami, Florida • Orlando, Florida

Conditions: Diastolic Dysfunction
Interventions: MITOQUINOL MESYLATE then placebo, Placebo, then MITOQUINOL MESYLATE; Dietary Supplement
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 50 Years to 75 Years
Enrollment: 31 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2030
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Respiratory Impairment, Elevated Blood Pressure, Physical Inactivity
Interventions: Increased lifestyle walking (intervention), Health education only (control); Other
Lead sponsor: Iowa State University; Other
Eligibility: 65 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Ames, Iowa

Conditions: Cardiovascular Disease
Interventions: Control, Peanut; Dietary Supplement
Lead sponsor: Penn State University; Other
Eligibility: 20 Years to 50 Years · Male only
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: University Park, Pennsylvania

Conditions: Cardiomyopathy, Hypertrophic, Cardiomyopathy, Hypertrophic, Familial
Interventions: Perhexiline, Use of bioanalytical assay to monitor plasma levels of perhexiline; Drug · Device
Lead sponsor: Heart Metabolics Limited; Industry
Eligibility: 18 Years and older
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 11
States / cities: Stanford, California • Indianapolis, Indiana • Baltimore, Maryland + 7 more

Conditions: Cognitive Impairment, Executive Dysfunction, Endothelial Dysfunction, Cardiovascular Disease
Interventions: Leuprolide acetate, Estradiol, Medroxyprogesterone, Placebo; Drug
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 40 Years to 60 Years · Female only
Enrollment: 17 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2017
U.S. locations: 2
States / cities: Aurora, Colorado • Boulder, Colorado

Conditions: Hypoplastic Left Heart, Congenital Heart Disease, Cyanotic Congenital Heart Disease, Cardiac Disease
Interventions: Norwood Palliation / DKS / Damus-Kaye-Stansel procedure; Procedure
Lead sponsor: Baylor College of Medicine; Other
Eligibility: Up to 2 Months
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Multiple Myeloma
Interventions: Oral microbiota assessment, Comprehensive chemical gustometry, Measurement of salivary flow, Surveys assessing taste disturbances; Diagnostic Test · Behavioral
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 21 Years and older
Enrollment: 47 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Diabetic Nephropathies, Coronary Artery Disease
Interventions: Allopurinol, Placebo; Drug
Lead sponsor: Alessandro Doria; Other
Eligibility: 18 Years to 70 Years
Enrollment: 530 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 23
States / cities: Aurora, Colorado • Denver, Colorado • Atlanta, Georgia + 15 more

Conditions: Acquired Brain Injury, Traumatic Brain Injury, Stroke
Interventions: Adapted Hatha Yoga, Low-Impact Exercise; Behavioral
Lead sponsor: Colorado State University; Other
Eligibility: 18 Years and older
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: Fort Collins, Colorado

Conditions: Airway Disease
Interventions: Beetroot Juice Group; Dietary Supplement
Lead sponsor: Southern Methodist University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 76 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Heart Failure, Dilated Cardiomyopathy
Interventions: clenbuterol; Drug
Lead sponsor: Francis D. Pagani; Other
Eligibility: 18 Years and older
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 7
States / cities: Washington D.C., District of Columbia • Chicago, Illinois • Ann Arbor, Michigan + 4 more

Conditions: Stroke, Chronic Stroke Patients, Arm Weakness as a Consequence of Stroke
Interventions: kTMP sham stimulation 9 weeks + active stimulation 9 weeks, kTMP 18 weeks; Device
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 80 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: San Francisco, California

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Physical and Functional Recovery From Cardiac Surgery in Hospitalized Patients: A Feasibility Pilot Study

Center of Research Translation (CORT) Project 2

Monocyte Phenotypic Changes in Heart Failure

Virtual Visits to Optimize Research Trial Offerings to HF Patients

Atherosclerosis, Immune Mediated Inflammation and Hypoestrogenemia in Young Women

The Effect of Acute Exercise on Cardiac Autonomic, Cerebrovascular, and Cognitive Function in Spinal Cord Injury

Effects of Secondhand Smoke on Flight Attendant Health

Rilonacept to Improve Artery Function in Patients With Atherosclerosis

Evaluating Two Exercise Training Programs to Reduce Leg Pain in People With Peripheral Arterial Disease (The EXERT Study)

Estrogen Alternatives Study

Testosterone and Neural Function in Men With Spinal Cord Injury

Evaluate Pharmacokinetics and Safety of BMS-986177 in Participants With Normal Renal Function and With Moderate or Severe Renal Impairment

MitoQ Supplementation and Cardiovascular Function in Healthy Men and Women

Walking and Blood Pressure in Older Adults With Respiratory Impairment.

The Effects of Peanuts and Peanut Products on Glucose Control and Vascular Function

Open-Label Study of Perhexiline in Patients With Hypertrophic Cardiomyopathy and Moderate to Severe Heart Failure

Vascular Mechanisms for the Effects of Loss of Ovarian Hormone Function on Cognition in Women

Cardiac Biomarkers in Patients With Single Ventricle Physiology

Prospective Evaluation of Taste Function In Multiple Myeloma Patients Undergoing Autologous Hematopoietic Cell Transplantation

A Multicenter Clinical Trial of Allopurinol to Prevent Kidney Function Loss in Type 1 Diabetes

Pilot Trial for Adults With Acquired Brain Injury

Nitrate Supplementation During Final Examination Stress

Harefield Recovery Protocol Study for Patients With Refractory Chronic Heart Failure

kTMP in Chronic Stroke