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ClinicalTrials.gov public records Last synced Nov 7, 2026, 1:34 PM EST

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Showing 745–768 of 1,410 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Cardiovascular Function Clear all
Terminated Not applicable Interventional

Investigating Effects of High-intensity Gait Training on Gait, Balance and Depression Post-stroke

NCT06373107
View directory record Official record
Conditions
Stroke
Interventions
High intensity gait training
Behavioral
Lead sponsor
Alvernia University
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Allentown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 11, 2025 · Synced Nov 7, 2026, 1:34 PM EST
Completed Early Phase 1 Interventional

A Novel Brain Stimulation for Bimanual Motor Function and Control in Chronic Stroke

NCT05381740
View directory record Official record
Conditions
Stroke
Interventions
Novel rTMS Approach, Sham rTMS Approach
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 3, 2024 · Synced Nov 7, 2026, 1:34 PM EST
Completed Not applicable Interventional Results available

High-intensity Inspiratory Muscle Training as a Pre-cardiac Rehabilitation in Heart Disease

NCT06127147
View directory record Official record
Conditions
Coronary Artery Bypass Graft, CABG
Interventions
IMT, Sham-IMT
Device
Lead sponsor
University of Illinois Chicago
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Nov 7, 2026, 1:34 PM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

Enhancing Language Function in Aphasia

NCT05443633
View directory record Official record
Conditions
Aphasia, Acquired, Language Disorders, Primary Progressive Aphasia, Stroke, Cerebrovascular
Interventions
individualized speech-language training, standard language intervention
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
21 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 9, 2024 · Synced Nov 7, 2026, 1:34 PM EST
Withdrawn No phase listed Observational

Electrocardiographic Autonomic Function Measures in Mechanically Ventilated Patients

NCT00844935
View directory record Official record
Conditions
Disorders of the Autonomic Nervous System, Cardiovascular Abnormalities, Respiratory Disorders
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 28, 2012 · Synced Nov 7, 2026, 1:34 PM EST
Completed No phase listed Observational

Transcranial Direct Current Stimulation to Improve Hand Movement in Stroke Patients

NCT00307385
View directory record Official record
Conditions
Stroke
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 80 Years
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Nov 7, 2026, 1:34 PM EST
Not listed Phase 3 Interventional

Safety and Effectiveness of Cortical Stimulation in the Treatment of Stroke Patients With Upper Extremity Hemiparesis

NCT00170716
View directory record Official record
Conditions
Stroke, Hemiparesis
Interventions
Cortical Stimulation and rehabilitation, Rehabilitation
Device · Other
Lead sponsor
Northstar Neuroscience
Industry
Eligibility
21 Years and older
Enrollment
174 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
21
States / cities
Tucson, Arizona • Los Angeles, California • San Francisco, California + 17 more
Source: ClinicalTrials.gov public record
Updated Dec 28, 2007 · Synced Nov 7, 2026, 1:34 PM EST
Completed Not applicable Interventional

Mitral Loop Cerclage(MLC) for Reducing Functional Mitral Regurgitation

NCT02471664
View directory record Official record
Conditions
Functional Mitral Regurgitation, Heart Failure
Interventions
Mitral Loop Cerclage Annuloplasty
Device
Lead sponsor
Tau-MEDICAL Co., Ltd.
Industry
Eligibility
20 Years to 85 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 13, 2017 · Synced Nov 7, 2026, 1:34 PM EST
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Pharmacokinetics of Eleclazine in Adults With Normal and Impaired Hepatic Function

NCT02412098
View directory record Official record
Conditions
Long QT Syndrome
Interventions
Eleclazine
Drug
Lead sponsor
Gilead Sciences
Industry
Eligibility
18 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
4
States / cities
Miami, Florida • Orlando, Florida • Minneapolis, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 29, 2019 · Synced Nov 7, 2026, 1:34 PM EST
Completed Phase 2 Interventional

Effects of Strength Training on Upper-Limb Function in Post-Stroke Hemiparesis

NCT00037908
View directory record Official record
Conditions
Cerebrovascular Accident, Hemiparesis
Interventions
Strength training
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2003
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jan 21, 2009 · Synced Nov 7, 2026, 1:34 PM EST
Withdrawn Not applicable Interventional Accepts healthy volunteers

Influence of Osmotic Stimulation of Vasopressin on Autonomic Function

NCT04233606
View directory record Official record
Conditions
Water Stress, Body Water Dehydration
Interventions
Hypertonic Saline, Normal Saline
Other
Lead sponsor
University of North Carolina, Greensboro
Other
Eligibility
18 Years to 35 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Greensboro, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 13, 2023 · Synced Nov 7, 2026, 1:34 PM EST
Completed Not applicable Interventional Results available

Exercise and Vascular Function in Postmenopausal Females With Hypertension

NCT05597033
View directory record Official record
Conditions
Hypertension
Interventions
Exercise, Control
Behavioral
Lead sponsor
Michigan State University
Other
Eligibility
55 Years to 80 Years · Female only
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Nov 7, 2026, 1:34 PM EST
Completed Phase 3 Interventional

Clinical Evaluation of the Physiological Diagnosis Function in the PARADYM CRT Device

NCT02167789
View directory record Official record
Conditions
Heart Failure
Interventions
Paradym CRT 8770
Device
Lead sponsor
LivaNova
Industry
Eligibility
18 Years and older
Enrollment
520 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
5
States / cities
Kaplan, Phoenix,, Arizona • Siegel, Phoenix,, Arizona • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 19, 2014 · Synced Nov 7, 2026, 1:34 PM EST
Completed Not applicable Interventional Results available

Impact of a Corrie Cardiac Rehabilitation Program

NCT05238103
View directory record Official record
Conditions
Coronary Artery Disease, Myocardial Infarction, Myocardial Ischemia, Coronary Artery Occlusion, Coronary Artery Stenosis Stent, Bypass Graft Occlusion, Valve Heart Disease
Interventions
Corrie Hybrid Cardiac Rehabilitation Program
Combination Product
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
259 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 5, 2025 · Synced Nov 7, 2026, 1:34 PM EST
Completed Phase 2 Interventional Accepts healthy volunteers

The Effect of Fasudil on Vascular Function in Humans

NCT00120718
View directory record Official record
Conditions
Atherosclerosis, Hypercholesterolemia
Interventions
fasudil
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2007
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 30, 2008 · Synced Nov 7, 2026, 1:34 PM EST
Completed Phase 4 Interventional Results available

A Pharmacodynamic Study Comparing Prasugrel Versus Ticagrelor in Patients Undergoing PCI With CYP2C19 Loss-of-function:

NCT02065479
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Prasugrel, Ticagrelor
Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 74 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 16, 2020 · Synced Nov 7, 2026, 1:34 PM EST
Completed Not applicable Interventional

Sulfasalazine and Endothelial Function

NCT00554203
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Sulfasalazine
Drug
Lead sponsor
Boston University
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 15, 2008 · Synced Nov 7, 2026, 1:34 PM EST
Completed Not applicable Interventional

Lakeshore Examination of Activity and Disability Exercise Response Study

NCT02533882
View directory record Official record
Conditions
Multiple Sclerosis, Stroke
Interventions
Movement to Music, Adapted Yoga
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 65 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 15, 2019 · Synced Nov 7, 2026, 1:34 PM EST
Completed Not applicable Interventional Results available

Functional Viability Duck Duck Punch

NCT03053492
View directory record Official record
Conditions
Rehabilitation, Recovery of Function, Stroke
Interventions
Duck Duck Punch Play, Commercially Available Game Play
Device · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 90 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 3, 2020 · Synced Nov 7, 2026, 1:34 PM EST
Completed Not applicable Interventional

Brain Volume and Cardiac Function in Heart Failure

NCT06623344
View directory record Official record
Conditions
Heart Failure
Interventions
Magnetic Resonance Imaging with or without Contrast
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Nov 7, 2026, 1:34 PM EST
Completed No phase listed Observational Accepts healthy volunteers

Brain Processing of Language Meanings

NCT00005004
View directory record Official record
Conditions
Central Nervous System Disease, Cerebrovascular Accident, Craniocerebral Trauma, Head Injury, Healthy, Stroke
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
Not listed
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Nov 7, 2026, 1:34 PM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

CALERIE: Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy

NCT00427193
View directory record Official record
Conditions
Aging
Interventions
Caloric Restriction (CR), Control
Behavioral
Lead sponsor
Duke University
Other
Eligibility
21 Years to 50 Years
Enrollment
238 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
3
States / cities
Baton Rouge, Louisiana • Boston, Massachusetts • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 16, 2022 · Synced Nov 7, 2026, 1:34 PM EST
Not listed Not applicable Interventional Accepts healthy volunteers

Improving Balance and Energetics of Walking Using a Hip Exoskeleton

NCT05447884
View directory record Official record
Conditions
Stroke
Interventions
A zero impedance mode, controlling a wearable bilateral hip exoskeleton, A personalized optimal assistance mode, controlling a wearable bilateral hip exoskeleton, A free walking mode, without wearing a wearable bilateral hip exoskeleton
Other
Lead sponsor
North Carolina State University
Other
Eligibility
18 Years to 64 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 20, 2023 · Synced Nov 7, 2026, 1:34 PM EST
Active, not recruiting Not applicable Interventional

Advancing Cath Lab Results With FFRangio Coronary Physiology Assessment

NCT05893498
View directory record Official record
Conditions
Percutaneous Coronary Intervention
Interventions
FFRangio, FFR or NHPR
Device
Lead sponsor
CathWorks Ltd.
Industry
Eligibility
18 Years and older
Enrollment
1,924 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
43
States / cities
La Jolla, California • Long Beach, California • Los Angeles, California + 34 more
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Nov 7, 2026, 1:34 PM EST