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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Cardiovascular Physiological Phenomena Clear all
Completed Not applicable Interventional Results available

Evaluating the Effects of a Study Medication on Exercise Function in Type 2 Diabetes

NCT01580813
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Acipimox, Placebo
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
30 Years to 60 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 2, 2021 · Synced Jul 23, 2026, 5:20 AM EDT
Completed Not applicable Interventional

Cardiovascular Function in Cancer Survivors

NCT03776149
View directory record Official record
Conditions
Cancer Survivor With History of Anthracycline Chemotherapy
Interventions
Beetroot juice, Black currant juice
Dietary Supplement
Lead sponsor
Kansas State University
Other
Eligibility
21 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Manhattan, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 30, 2022 · Synced Jul 23, 2026, 5:20 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Assess the Effect of Treating Periodontal Disease on Cardiovascular Function in Young Adults

NCT01376791
View directory record Official record
Conditions
Periodontal Disease, Atherosclerosis
Interventions
Not listed
Lead sponsor
San Diego State University
Other
Eligibility
21 Years to 40 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Valley Center, California
Source: ClinicalTrials.gov public record
Updated Apr 22, 2013 · Synced Jul 23, 2026, 5:20 AM EDT
Terminated Not applicable Interventional Results available

Impact of Respiratory Training in Lymphoma Survivors

NCT05938127
View directory record Official record
Conditions
Hodgkin Lymphoma, Non Hodgkin Lymphoma
Interventions
Inspiratory muscle strength training, Sham Inspiratory muscle strength training
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 80 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
2
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Jul 23, 2026, 5:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

CALERIE: Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy

NCT00427193
View directory record Official record
Conditions
Aging
Interventions
Caloric Restriction (CR), Control
Behavioral
Lead sponsor
Duke University
Other
Eligibility
21 Years to 50 Years
Enrollment
238 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
3
States / cities
Baton Rouge, Louisiana • Boston, Massachusetts • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 15, 2022 · Synced Jul 23, 2026, 5:20 AM EDT
Recruiting Phase 1 Interventional

Using taVNS to Modulate Cardiovascular Function in Individuals With Neurologic Disease

NCT07557706
View directory record Official record
Conditions
PARKINSON DISEASE (Disorder)
Interventions
transcutaneous auricular vagus nerve stimulation
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Jul 23, 2026, 5:20 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Metabolic Effects of Natriuretic Peptide Hormones

NCT03397966
View directory record Official record
Conditions
Obesity, Cardiovascular Physiological Phenomena, Metabolism
Interventions
recombinant human BNP(1-32), placebo (control, normal saline)
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 40 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
2
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 24, 2024 · Synced Jul 23, 2026, 5:20 AM EDT
Recruiting Not applicable Interventional

Transcutaneous Spinal Cord Stimulation Combined With Arm Bike for Cardiovascular Recovery in SCI

NCT06313515
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Transcutaneous Spinal Cord Stimulation, Arm-crank bike exercise, Sham Stimulation
Device · Behavioral · Other
Lead sponsor
University of Washington
Other
Eligibility
21 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Jul 23, 2026, 5:20 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Effects of Liothyronine on Energy Expenditure and Cardiovascular Function

NCT03098433
View directory record Official record
Conditions
Healthy
Interventions
Liothyronine, Levothyroxine, Placebos
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 45 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 25, 2021 · Synced Jul 23, 2026, 5:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ketone Esters for Appetite, Cognition, and Cardiovascular Function in Individuals With Obesity and Insulin Resistance

NCT05651243
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Ketone Ester Supplement, Placebo
Dietary Supplement · Other
Lead sponsor
University of Southern Mississippi
Other
Eligibility
18 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Hattiesburg, Mississippi
Source: ClinicalTrials.gov public record
Updated May 21, 2024 · Synced Jul 23, 2026, 5:20 AM EDT
Completed Phase 3 Interventional Results available

EMERALD: Effects of Metformin on Cardiovascular Function in Adolescents With Type 1 Diabetes

NCT01808690
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
Metformin, Placebo
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
12 Years to 21 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 29, 2021 · Synced Jul 23, 2026, 5:20 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Beige Fat, Energy, and the Natriuretic Peptide System

NCT04357964
View directory record Official record
Conditions
Obesity
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 55 Years
Enrollment
137 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
2
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 31, 2024 · Synced Jul 23, 2026, 5:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Pumpkin Seed Oil Supplementation on Cardiovascular Function in Postmenopausal Women.

NCT03716960
View directory record Official record
Conditions
Elevated Blood Pressure, Hypertension
Interventions
Pumpkin Seed Oil, Placebo
Other
Lead sponsor
Marymount University
Other
Eligibility
45 Years to 65 Years · Female only
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Arlington, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 23, 2018 · Synced Jul 23, 2026, 5:20 AM EDT
Recruiting Phase 1 Interventional

MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes

NCT05065372
View directory record Official record
Conditions
Type 1 Diabetes, Diabetic Kidney Disease, Cardiovascular Diseases, Endothelial Dysfunction, Insulin Sensitivity
Interventions
Metformin Hcl 1000Mg Tab, Aminohippurate Sodium 20 % Injection, Iohexol 300 Mg/mL Injectable Solution, Placebo
Drug
Lead sponsor
Kalie Tommerdahl
Other
Eligibility
12 Years to 25 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Aurora, Colorado • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Jul 23, 2026, 5:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Aerobic Interval Training on Cardiovascular Function in Aging

NCT01883271
View directory record Official record
Conditions
Aging
Interventions
High intensity aerobic interval training, Continuous moderate intensity exercise
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 79 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 24, 2019 · Synced Jul 23, 2026, 5:20 AM EDT
Completed Not applicable Interventional Results available

Recovery of Cardiovascular Function With Epidural Stimulation After Human Spinal Cord Injury

NCT02037620
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
5-6-5 Specify electrode, Restore Advance Pulse Generator
Device
Lead sponsor
University of Louisville
Other
Eligibility
21 Years to 70 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 27, 2022 · Synced Jul 23, 2026, 5:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Role of Flavanols In Cardiovascular Function in Healthy Aging

NCT01395277
View directory record Official record
Conditions
Aging
Interventions
High Flavanol first then Low Flavanol, Low Flavanol first then High Flavanol
Dietary Supplement
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Aug 9, 2015 · Synced Jul 23, 2026, 5:20 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

The Effects of Low Dose Ketamine on Cardiovascular Function

NCT04429685
View directory record Official record
Conditions
Healthy
Interventions
Ketamine, Saline (placebo)
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 45 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 20, 2024 · Synced Jul 23, 2026, 5:20 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Effect of Simulated Burn Injury on Post Exercise Recovery in Hot Environments

NCT07050264
View directory record Official record
Conditions
Burn Injury, Body Temperature Regulation, Cardiovascular Physiology
Interventions
Simulated burn injury via application of absorbent and impermeable material over 60% of the body
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Jul 23, 2026, 5:20 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effects of Sleep Loss on Endothelial Function and Cytokine Levels in Internal Medicine Residents

NCT00272233
View directory record Official record
Conditions
Sleep Deprivation
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
18 Years to 40 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 19, 2007 · Synced Jul 23, 2026, 5:20 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effect of Energy Drink Ingredients on Cardiovascular Function in Men and Women 18-39 Years Old

NCT04149717
View directory record Official record
Conditions
Cardiac Arrhythmia, Blood Pressure
Interventions
Energy Drink Ingredients and Exercise
Dietary Supplement
Lead sponsor
Duquesne University
Other
Eligibility
18 Years to 39 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 22, 2021 · Synced Jul 23, 2026, 5:20 AM EDT
Recruiting No phase listed Observational

QuantaFlo HD Clinical Validation Study

NCT07219693
View directory record Official record
Conditions
To Assess Cardiovascular Function
Interventions
QuantaFlo HD
Device
Lead sponsor
Semler Scientific
Industry
Eligibility
22 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Jul 23, 2026, 5:20 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Vascular Function and Oxidative Stress in Emergency Medical Responders

NCT06985394
View directory record Official record
Conditions
Cardiovascular Function in EMTs
Interventions
Antioxidant cocktail, Placebo
Dietary Supplement
Lead sponsor
University of Delaware
Other
Eligibility
20 Years to 40 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated May 21, 2025 · Synced Jul 23, 2026, 5:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Role of Mitochondrial-derived Oxidative Stress to Promote Vascular Endothelial Dysfunction in Non-exercisers With Aging

NCT05872139
View directory record Official record
Conditions
Aging, Endothelial Dysfunction, Cardiovascular Function, Arterial Stiffness
Interventions
Placebo, Mitoquinone Mesylate
Dietary Supplement
Lead sponsor
Ball State University
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Muncie, Indiana
Source: ClinicalTrials.gov public record
Updated May 23, 2023 · Synced Jul 23, 2026, 5:20 AM EDT