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ClinicalTrials.gov public records Last synced Oct 21, 2026, 10:43 PM EDT

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Showing 193–216 of 877 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Cardiovascular Surgery Clear all
Completed No phase listed Observational

Motor Development of Children That Have Surgery as Newborns for Complex Congenital Heart Disease

NCT02781545
View directory record Official record
Conditions
Heart Defects, Congenital
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
Up to 24 Months
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Oak Lawn, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 4, 2024 · Synced Oct 21, 2026, 10:43 PM EDT
Completed Not applicable Interventional

Cardiopulmonary Circuits in the Pediatric Population

NCT00208728
View directory record Official record
Conditions
Pediatric, Cardiac Surgery
Interventions
PC/SMART cardiopulmonary bypass circuit, PMEA modified cardiopulmonary bypass circuit, Standard of care uncoated cardiopulmonary bypass circuit
Device
Lead sponsor
Emory University
Other
Eligibility
Not listed
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 27, 2013 · Synced Oct 21, 2026, 10:43 PM EDT
Completed Phase 3 Interventional

Intravenous L-Citrulline to Treat Children Undergoing Heart Bypass Surgery

NCT00335244
View directory record Official record
Conditions
Heart Defects, Congenital, Hypertension, Pulmonary
Interventions
L-citrulline, Placebo of intravenous L-citrulline
Drug
Lead sponsor
Asklepion Pharmaceuticals, LLC
Industry
Eligibility
Up to 17 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 2, 2015 · Synced Oct 21, 2026, 10:43 PM EDT
Terminated Not applicable Interventional Results available

Perceval Sutureless Implant Versus Standard-Aortic Valve Replacement

NCT02673697
View directory record Official record
Conditions
Aortic Valve Disease, Aortic Stenosis
Interventions
Perceval valve, other stented biological valve
Device
Lead sponsor
Corcym S.r.l
Industry
Eligibility
18 Years and older
Enrollment
914 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
5
States / cities
Indianapolis, Indiana • Portland, Maine • Cleveland, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 6, 2024 · Synced Oct 21, 2026, 10:43 PM EDT
Completed Phase 2 Interventional Results available

Fixed Versus Weight-Based Enoxaparin Dosing in Thoracic Surgery Patients

NCT03251963
View directory record Official record
Conditions
Venous Thromboembolism, Deep Venous Thrombosis, Surgery
Interventions
Fixed Dose Enoxaparin, Variable Dose Enoxaparin
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 8, 2020 · Synced Oct 21, 2026, 10:43 PM EDT
Enrolling by invitation No phase listed Observational

Clinical Registry Collecting Real World Evidence on Wound Care Treatments

NCT06328010
View directory record Official record
Conditions
Wounds and Injuries, Burns, Mohs Surgery, Diabetic Foot Ulcer Mixed, Venous Leg Ulcer, Non-healing Wound, Trauma Injury, Injury and Wounds, Degloving Injuries, Pressure Ulcers, Bedsores, Decubitus Ulcer
Interventions
Various types of wound care treatments
Combination Product
Lead sponsor
Siddhey LLC
Industry
Eligibility
18 Years and older
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
12
States / cities
Scottsdale, Arizona • Tempe, Arizona • Tucson, Arizona + 8 more
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Oct 21, 2026, 10:43 PM EDT
Recruiting Not applicable Interventional

Rapid Evacuation and Access of Cerebral Hemorrhage Trial

NCT06870812
View directory record Official record
Conditions
Stroke Hemorrhagic
Interventions
Surgical management, Medical Management
Procedure · Other
Lead sponsor
Emory University
Other
Eligibility
18 Years to 70 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
24
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Palo Alto, California + 19 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 21, 2026, 10:43 PM EDT
Completed No phase listed Observational

Evaluation of Coagulation Testing in Patients Undergoing Cardiac Surgery

NCT02410473
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
Discarded blood samples, Discarded Urine Sample
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 21, 2026, 10:43 PM EDT
Terminated Phase 3 Interventional Results available

Esmolol for Treatment of Perioperative Tachycardia

NCT01208402
View directory record Official record
Conditions
High-risk, Non-cardiovascular Surgeries
Interventions
Esmolol
Drug
Lead sponsor
Duke University
Other
Eligibility
41 Years and older
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
3
States / cities
Durham, North Carolina • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 12, 2014 · Synced Oct 21, 2026, 10:43 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Cognitive Dysfunction in Hypertensive Patients Having Spine Surgery

NCT01140854
View directory record Official record
Conditions
Hypertension
Interventions
Lumbar spine surgery, Neurologic/neuropsychometric examinations
Procedure · Other
Lead sponsor
Columbia University
Other
Eligibility
60 Years to 90 Years
Enrollment
179 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 4, 2015 · Synced Oct 21, 2026, 10:43 PM EDT
Recruiting Not applicable Interventional

CLOSM Trial: Groin Closure Using Layered Option for Suture Material

NCT06990425
View directory record Official record
Conditions
Vascular Diseases
Interventions
Groin closure with PDS suture, Groin closure suture material
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
259 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 21, 2026, 10:43 PM EDT
Completed No phase listed Observational

BabySparks Developmental Application Pilot Study

NCT03867903
View directory record Official record
Conditions
Development, Child, Adherence, Patient, Congenital Heart Disease
Interventions
Babysparks Application, pre and post-test Redcap Survey
Device · Other
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
Up to 18 Months
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated May 18, 2023 · Synced Oct 21, 2026, 10:43 PM EDT
Completed Phase 3 Interventional

Response to RSD1235 Compared to Placebo in Subjects With Atrial Arrhythmia After Heart Surgery

NCT00125320
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Flutter
Interventions
RSD1235
Drug
Lead sponsor
Astellas Pharma Inc
Industry
Eligibility
18 Years and older
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
2
States / cities
Fort Lauderdale, Florida • Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 24, 2007 · Synced Oct 21, 2026, 10:43 PM EDT
Completed Phase 3 Interventional

Study of Clevidipine Assessing Its Postoperative Antihypertensive Effect in Cardiac Surgery (ESCAPE-2)

NCT00093262
View directory record Official record
Conditions
Hypertension
Interventions
clevidipine, placebo
Drug
Lead sponsor
The Medicines Company
Industry
Eligibility
18 Years and older
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
15
States / cities
Mobile, Alabama • Los Angeles, California • Pasadena, California + 11 more
Source: ClinicalTrials.gov public record
Updated May 8, 2014 · Synced Oct 21, 2026, 10:43 PM EDT
Terminated No phase listed Observational

PRONTO: Artemis in the Removal of Intraventricular Hemorrhage in the Hyper-Acute Phase

NCT04178746
View directory record Official record
Conditions
Intracerebral Hemorrhage, Brain Hemorrhage, Intraventricular Hemorrhage
Interventions
Artemis Neuro Evacuation Device
Device
Lead sponsor
Penumbra Inc.
Industry
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Summit, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 14, 2022 · Synced Oct 21, 2026, 10:43 PM EDT
Active, not recruiting Not applicable Interventional

AtriCure CryoICE Lesions for Persistent and Long-standing Persistent Atrial Fibrillation Treatment

NCT03732794
View directory record Official record
Conditions
Atrial Fibrillation (AF), Persistent Atrial Fibrillation, Longstanding Persistent Atrial Fibrillation
Interventions
AtriCure CryoICE & AtriClip LAA Exclusion
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
15
States / cities
Los Angeles, California • Washington D.C., District of Columbia • Chicago, Illinois + 10 more
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Oct 21, 2026, 10:43 PM EDT
Completed Phase 2 Interventional Results available

Parasternal Nerve Block in Cardiac Patients

NCT01826851
View directory record Official record
Conditions
Coronary Artery Disease, Pain, Postoperative
Interventions
Exparel, Placebo
Drug
Lead sponsor
Peter A Knight
Other
Eligibility
18 Years and older
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Aug 1, 2018 · Synced Oct 21, 2026, 10:43 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

PCC vs. FFP for Post Cardiopulmonary Bypass Coagulopathy and Bleeding

NCT02557672
View directory record Official record
Conditions
Bleeding, Blood Loss, Surgical, Cardiovascular Surgical Procedures, Prothrombin Complex Concentrates, Fresh Frozen Plasma
Interventions
Prothrombin complex concentrate (Human), Fresh frozen plasma (FFP)
Drug · Biological
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 7, 2022 · Synced Oct 21, 2026, 10:43 PM EDT
Recruiting Phase 1Phase 2 Interventional

Amiodarone-Infused CardiaMend Patches for the Prevention of New-Onset POAF in Cardiac Surgery Subjects

NCT06730828
View directory record Official record
Conditions
Atrial Fibrillation, Postoperative
Interventions
The intervention includes Amiodarone-Infused CardiaMend patches (70mg, 150mg and 300mg)
Combination Product
Lead sponsor
Helios Cardio Inc.
Industry
Eligibility
20 Years to 85 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 12, 2024 · Synced Oct 21, 2026, 10:43 PM EDT
Withdrawn Phase 3 Interventional Accepts healthy volunteers

Perioperative Bleeding and Aspirin Use in Spine Surgery

NCT02807441
View directory record Official record
Conditions
Hemorrhage, Thrombosis
Interventions
Acetylsalicylic acid
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 11, 2021 · Synced Oct 21, 2026, 10:43 PM EDT
Terminated Phase 3 Interventional

Guidant Microwave Ablation System for the Treatment of Atrial Fibrillation

NCT00111488
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Flex 4 and Generator
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
21
States / cities
La Jolla, California • Long Beach, California • Los Angeles, California + 16 more
Source: ClinicalTrials.gov public record
Updated Jan 6, 2016 · Synced Oct 21, 2026, 10:43 PM EDT
Completed Not applicable Interventional Results available

A Study to Determine if Carbon Dioxide Lavage During Total Knee Surgery Reduces Intraoperative Embolic Events

NCT00736125
View directory record Official record
Conditions
Postoperative Complications, Memory Disorders
Interventions
pulsatile saline lavage, carbon dioxide lavage
Device
Lead sponsor
Kinamed Incorporated
Industry
Eligibility
50 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 26, 2019 · Synced Oct 21, 2026, 10:43 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of Prevena Therapy on Obese and or Diabetic Patients With Surgical Groin Sites

NCT01983215
View directory record Official record
Conditions
Obesity, Diabetes, Peripheral Vascular Disease
Interventions
Prevena vac
Device
Lead sponsor
Dr. Jean E. Starr, MD
Other
Eligibility
18 Years and older
Enrollment
276 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 25, 2017 · Synced Oct 21, 2026, 10:43 PM EDT
Terminated Phase 2 Interventional Results available

Safety and Suitability of Supplementing Early MIP Surgery (MIPS) of ICH With Pioglitazone

NCT05582707
View directory record Official record
Conditions
Intracerebral Haemorrhage, Intraventricular
Interventions
Pioglitazone 15mg
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 80 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 21, 2026, 10:43 PM EDT