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Showing 1–24 of 37 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Carpal Tunnel Release Clear all
Completed Phase 4 Interventional

Length of Post Operative Dressing After Carpal Tunnel Release

NCT01310218
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
extended postoperative dressing, short postoperative dressing
Other
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 7, 2011 · Synced Sep 24, 2026, 2:28 PM EDT
Completed Not applicable Interventional

Patient Outcomes With Endoscopic Versus Open Carpal Tunnel Release

NCT00880295
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
endoscopic carpal tunnel release, open carpal tunnel release
Procedure
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 75 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 23, 2017 · Synced Sep 24, 2026, 2:28 PM EDT
Terminated Not applicable Interventional

Comparative Study of Two Incision vs. Mini Open Carpal Tunnel Release

NCT05325567
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Mini open incision CTR
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 17, 2023 · Synced Sep 24, 2026, 2:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Outcomes of USCTR vs. mOCTR

NCT04504019
View directory record Official record
Conditions
Carpal Tunnel
Interventions
USCTR, mOCTR
Device · Procedure
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years to 89 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 25, 2025 · Synced Sep 24, 2026, 2:28 PM EDT
Withdrawn No phase listed Observational

Staged Bilateral Carpal Tunnel Release: Which Side Hurts More?

NCT02198521
View directory record Official record
Conditions
Carpal Tunnel Syndrome, Pain
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 2, 2017 · Synced Sep 24, 2026, 2:28 PM EDT
Completed Phase 1 Interventional

The Effect Of An Anesthetic Procedure On Post Operative Pain Management In Carpal Tunnel Release

NCT03729375
View directory record Official record
Conditions
Pain, Postoperative, Carpal Tunnel Syndrome
Interventions
10cc injection of bupivacaine, 20cc injection of bupivacaine
Drug
Lead sponsor
University of South Florida
Other
Eligibility
Not listed
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced Sep 24, 2026, 2:28 PM EDT
Terminated Not applicable Interventional

Evaluation of the MANOS Carpal Tunnel Release System in Patients With Carpal Tunnel Syndrome

NCT01450735
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
MANOS CTR™
Device
Lead sponsor
Thayer Intellectual Property, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
3
States / cities
Hayward, California • San Francisco, California • Willits, California
Source: ClinicalTrials.gov public record
Updated Jan 14, 2013 · Synced Sep 24, 2026, 2:28 PM EDT
Completed No phase listed Observational

Very Early Outcomes in Endoscopic Versus Open Carpal Tunnel Release

NCT07364604
View directory record Official record
Conditions
Carpal Tunnel Syndrome (CTS)
Interventions
Carpal Tunnel Release
Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Sep 24, 2026, 2:28 PM EDT
Terminated Not applicable Interventional

A Comparison of Incisionless Ultrasound Guided Thread Carpal Tunnel Release and Mini Open Carpal in Patients With Bilateral Carpal Tunnel Syndrome

NCT03906604
View directory record Official record
Conditions
Carpal Tunnel Syndrome Bilateral
Interventions
Carpal Tunnel Procedure (open)
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 5, 2022 · Synced Sep 24, 2026, 2:28 PM EDT
Completed Not applicable Interventional

Carpal Tunnel Syndrome: Diagnosis and Treatment Trial

NCT00032227
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Early Carpal Tunnel Release for Mild or Moderate CTS, MR Nerve Imaging for CTS
Procedure · Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 6, 2013 · Synced Sep 24, 2026, 2:28 PM EDT
Completed Not applicable Interventional Results available

Trial of Ultrasound Guided Carpal Tunnel Release Versus Traditional Open Release (TUTOR)

NCT05405218
View directory record Official record
Conditions
Carpal Tunnel Syndrome, CTS, Carpal Tunnel
Interventions
CTR with Ultrasound Guidance using the UltraGuideCTR device, mOCTR
Device · Procedure
Lead sponsor
Sonex Health, Inc.
Industry
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
12
States / cities
Sonora, California • Fort Walton Beach, Florida • Evansville, Indiana + 9 more
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Sep 24, 2026, 2:28 PM EDT
Active, not recruiting No phase listed Observational

Registry of the Patient Experience for Carpal Tunnel Release

NCT06071468
View directory record Official record
Conditions
Carpal Tunnel Syndrome, CTS
Interventions
UltraGuideCTR (Device) with Ultrasound Guided Carpal Tunnel Release (CTR-US), Endocscopic CTR, Open CTR
Device · Procedure
Lead sponsor
Sonex Health, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1,424 participants
Timeline
2024 – 2027
U.S. locations
33
States / cities
Foley, Alabama • Scottsdale, Arizona • Glastonbury, Connecticut + 30 more
Source: ClinicalTrials.gov public record
Updated Sep 13, 2026 · Synced Sep 24, 2026, 2:28 PM EDT
Terminated Not applicable Interventional Results available

PRP as Adjuvant Treatment to CTR for Severe CTS Tunnel Syndrome

NCT04811287
View directory record Official record
Conditions
Carpal Tunnel Syndrome, PRP
Interventions
Carpal Tunnel Release with Platelet-Rich Plasma, Carpal Tunnel Release without Platelet-Rich Plasma
Device · Procedure
Lead sponsor
Michael Fredericson, MD
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Sep 24, 2026, 2:28 PM EDT
Terminated Not applicable Interventional

Does Addition of a Vessel Loop in Wound Closure Improve Suture Removal?

NCT04339439
View directory record Official record
Conditions
Patient Satisfaction, Suture, Complication
Interventions
Vessel loop (FDA product code FZZ)
Device
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years to 79 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 13, 2023 · Synced Sep 24, 2026, 2:28 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Bilateral vs Unilateral CTR

NCT01961011
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
2
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 10, 2013 · Synced Sep 24, 2026, 2:28 PM EDT
Completed Not applicable Interventional Results available

Multicenter Prospective Trial of Office-based Carpal Tunnel Release With Ultrasound Guidance (ROBUST)

NCT05675046
View directory record Official record
Conditions
Carpal Tunnel Syndrome, CTS
Interventions
Carpal Tunnel Release with Ultrasound Guidance using the UltraGuideCTR device
Device
Lead sponsor
Sonex Health, Inc.
Industry
Eligibility
18 Years and older
Enrollment
149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
7
States / cities
Fort Walton Beach, Florida • Vero Beach, Florida • Atlanta, Georgia + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 5, 2026 · Synced Sep 24, 2026, 2:28 PM EDT
Recruiting Not applicable Interventional

Effect of Cooling Therapy for Post-Operative Pain in Open Carpal Tunnel Release

NCT05783245
View directory record Official record
Conditions
Carpal Tunnel Syndrome, Perioperative/Postoperative Complications
Interventions
Polarcare Machine, Standard of care ice therapy
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Sep 24, 2026, 2:28 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Acute Human Study: StimRouter for Peripheral Nerve Stimulation of Discrete Peripheral Nerves

NCT00665132
View directory record Official record
Conditions
Unilateral Carpal Tunnel Syndrome
Interventions
StimRouter System
Device
Lead sponsor
Bioness Inc
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Charleston, West Virginia
Source: ClinicalTrials.gov public record
Updated Jun 5, 2016 · Synced Sep 24, 2026, 2:28 PM EDT
Completed Not applicable Interventional

Early Motion Following Carpal Tunnel Release

NCT00845325
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Group One, Control Group Two
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
Not listed
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 28, 2016 · Synced Sep 24, 2026, 2:28 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Pain Outcomes of Intra-operative IV Tylenol and/or IV Toradol for Carpal Tunnel and Distal Radius Fracture Surgeries

NCT02313675
View directory record Official record
Conditions
Postoperative Pain, Carpal Tunnel Release, Distal Radius Fracture
Interventions
Acetaminophen, Ketorolac Tromethamine, Saline
Drug
Lead sponsor
John Fowler
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 3, 2018 · Synced Sep 24, 2026, 2:28 PM EDT
Withdrawn Not applicable Interventional

Comparison of Bupivacaine and Exparel for Carpal Tunnel Release

NCT02141178
View directory record Official record
Conditions
Pain After Carpal Tunnel Release
Interventions
Bupivacaine, Exparel
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 89 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 4, 2016 · Synced Sep 24, 2026, 2:28 PM EDT
Terminated Phase 4 Interventional Results available

Patient Satisfaction With Pain Relief After Ambulatory Hand Surgery

NCT01588158
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Acetaminophen, Vicodin
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 13, 2017 · Synced Sep 24, 2026, 2:28 PM EDT
Terminated No phase listed Observational

Corticosteroid Injection as a Predictor of Outcome in Carpal Tunnel Release

NCT00655915
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Corticosteroid Injection- 1ml of Betamethasone and 1 ml of 1% Lidocaine
Other
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 8, 2011 · Synced Sep 24, 2026, 2:28 PM EDT