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Showing 1–24 of 28 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2027
U.S. locations
3
States / cities
Rochester, Minnesota • New York, New York • Nashville, Tennessee
Conditions
Osteoarthritis
Interventions
sodium hyaluronate, placebo
Device
Lead sponsor
Ferring Pharmaceuticals
Industry
Eligibility
40 Years and older
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
St. Petersburg, Florida
Completed No phase listed Observational Accepts healthy volunteers Results available

Thumb Osteoarthritis: A Cross-Sectional Study of Mechanisms

NCT04104477
Conditions
Carpometacarpal Osteoarthritis
Interventions
Range of Motion Tasks, Strength Tasks
Other
Lead sponsor
University of Florida
Other
Eligibility
40 Years to 90 Years · Female only
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Osteoarthritis
Interventions
Cartiva
Device
Lead sponsor
Cartiva, Inc.
Industry
Eligibility
22 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
5
States / cities
San Diego, California • Atlanta, Georgia • Indianapolis, Indiana + 2 more
Conditions
Carpometacarpal Osteoarthritis
Interventions
Synvisc (hylan G-F20)
Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
45 Years to 95 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
New York, New York
Conditions
Osteoarthritis
Interventions
Synvisc (Hylan G-F20; hyaluronan injection), Bupivicaine (local anesthesia injection), Kenalog (triamcinolone; corticosteroid injection)
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
45 Years to 95 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
New York, New York
Conditions
Carpometacarpal Osteoarthritis
Interventions
Acetaminophen, Placebo: Multivitamin
Drug · Other
Lead sponsor
Indiana Hand to Shoulder Center
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Indianapolis, Indiana
Recruiting No phase listed Observational

TOUCH® CMC 1 New Enrollment US Study

NCT07405983
Conditions
Osteoarthritis Thumb, Thumb Carpometacarpal Joint Osteoarthritis
Interventions
TOUCH® CMC 1 Prosthesis
Device
Lead sponsor
Keri Medical SA
Industry
Eligibility
22 Years and older
Enrollment
163 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
4
States / cities
Aurora, Colorado • Indianapolis, Indiana • Morrisville, North Carolina + 1 more
Conditions
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Interventions
casts for the thumb, Motion group
Other
Lead sponsor
University of Utah
Other
Eligibility
40 Years to 80 Years
Enrollment
234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2019
U.S. locations
1
States / cities
Murray, Utah
Conditions
Osteoarthritis, Osteoarthritis Thumb Base Joint, Carpometacarpal Osteoarthritis, Thumb
Interventions
CTM, Placebo
Device · Other
Lead sponsor
Indiana Hand to Shoulder Center
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Indianapolis, Indiana
Conditions
Arthritis of Carpometacarpal Joint of Left Thumb, Arthritis of Carpometacarpal Joint of Right Thumb
Interventions
Curcumin, Placebo
Drug
Lead sponsor
Brent DeGeorge
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Conditions
Thumb Osteoarthritis
Interventions
Denervation of the thumb CMC joint, trapeziectomy with ligament reconstruction (LRTI)
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
53 participants
Timeline
2018 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Thumb Osteoarthritis
Interventions
Video assisted home therapy
Other
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Roanoke, Virginia
Conditions
Carpometacarpal (CMC) Osteoarthritis
Interventions
Triamcinolone Acetonide extended release suspension
Drug
Lead sponsor
Marie Badalamente
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Stony Brook, New York
Completed Phase 2 Interventional Results available

Mechanisms of a Dynamic Stability Approach

NCT05247398
Conditions
Thumb Carpometacarpal Osteoarthritis, Thumb Basal Joint Osteoarthritis
Interventions
Dynamic Stability Exercise Program
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Arthritis
Interventions
Meniscal allograft arthroplasty of the carpometacarpal joint of the thumb
Procedure
Lead sponsor
Corewell Health East
Other
Eligibility
25 Years to 95 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Royal Oak, Michigan
Conditions
Thumb Arthritis
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 80 Years
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Thumb Carpometacarpal Joint Osteoarthritis
Interventions
Platelet-rich plasma
Biological
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Interventions
Arthroplasty
Procedure
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Thumb Osteoarthritis
Interventions
Immobilization for 2-weeks postoperative, Immobilization for 6-weeks postoperative
Other
Lead sponsor
University of Chicago
Other
Eligibility
40 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Completed Not applicable Interventional Accepts healthy volunteers Results available

Influence of Custom Orthosis Post Carpometacarpal (CMC) Arthroplasty

NCT05307510
Conditions
Thumb Osteoarthritis
Interventions
Prefabricated splint, Custom Orthosis
Device
Lead sponsor
University of Toledo
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Toledo, Ohio
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Prolotherapy Versus Steroids for Thumb Carpo-metacarpal Joint Arthritis

NCT00685880
Conditions
Thumb Carpometacarpal Joint Osteoarthritis
Interventions
Prolotherapy (10% dextrose solution), Betamethasone
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
45 Years and older
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Pain, Osteoarthritis
Interventions
Standard of Care Hand Therapy
Other
Lead sponsor
Gannon University
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Ruskin, Florida
Completed Not applicable Interventional Results available

LRTI vs Internal Brace for CMC OA

NCT03971188
Conditions
Thumb Carpometacarpal Osteoarthritis
Interventions
Trapeziectomy with Internal Brace
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
50 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
3
States / cities
St Louis, Missouri