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ClinicalTrials.gov public records Last synced Jul 22, 2026, 2:48 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cartilage Clear all
Completed No phase listed Observational

Longitudinal Evaluation of Hip Cartilage Degeneration: FAI

NCT02408276
View directory record Official record
Conditions
Femoroacetabular Impingement
Interventions
dGEMERIC MRI technique
Other
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
10 Years to 35 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 21, 2025 · Synced Jul 22, 2026, 2:48 PM EDT
Not listed Not applicable Interventional

Safety and Effectiveness of Cartiva Implant in the Treatment of First CMC Joint Osteoarthritis Compared to LRTI (GRIP 2)

NCT03247439
View directory record Official record
Conditions
Osteoarthritis
Interventions
Cartiva
Device
Lead sponsor
Cartiva, Inc.
Industry
Eligibility
22 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
5
States / cities
San Diego, California • Atlanta, Georgia • Indianapolis, Indiana + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 2, 2020 · Synced Jul 22, 2026, 2:48 PM EDT
Active, not recruiting Not applicable Interventional

Evaluate the Safety and Effectiveness of the Polymotion Hip Resurfacing (PHR) System Compared to Total Hip Arthroplasty

NCT06792539
View directory record Official record
Conditions
Osteoarthritis of the Hip, Degenerative Joint Disease of Hip, Dysplasia; Hip
Interventions
Polymotion Hip Resurfacing (PHR) System
Device
Lead sponsor
JointMedica Inc.
Other
Eligibility
21 Years to 65 Years
Enrollment
238 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
8
States / cities
Tampa, Florida • Chicago, Illinois • Baltimore, Maryland + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Jul 22, 2026, 2:48 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Everyday Activity Shoes: a Quantification of Impact Forces While Walking

NCT04197362
View directory record Official record
Conditions
Impact Forces
Interventions
Evaluation
Other
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 8, 2024 · Synced Jul 22, 2026, 2:48 PM EDT
Completed Not applicable Interventional

Changes in Quadriceps Function Following Local or Distant Interventions in Individuals With Patellofemoral Pain

NCT01434966
View directory record Official record
Conditions
Patellofemoral Pain Syndrome, Chondromalacia Patellae, Anterior Knee Pain Syndrome
Interventions
Lumbopelvic Manipulation, TENS- Spine, TENS- Knee
Other
Lead sponsor
Creighton University
Other
Eligibility
15 Years to 50 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Dec 13, 2015 · Synced Jul 22, 2026, 2:48 PM EDT
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

Impact of Mesenchymal Stem Cells in Knee Osteoarthritis

NCT03477942
View directory record Official record
Conditions
Musculoskeletal Pain, Knee Osteoarthritis, Cartilage Injury, Cartilage Degeneration
Interventions
Autologous Mesenchymal Stem Cells
Biological
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Jul 22, 2026, 2:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Unloader Bracing in Clinical Outcome and Cartilage Physiology Following Microfracture of Chondral Defects

NCT02016300
View directory record Official record
Conditions
Cartilage Loss, Microfracture
Interventions
Unloader Bracing, Non-Bracing
Device
Lead sponsor
Stanford University
Other
Eligibility
15 Years to 40 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Jun 26, 2019 · Synced Jul 22, 2026, 2:48 PM EDT
Recruiting Phase 3 Interventional

Phase 3 Pivotal Trial Comparing CARTISTEM® and Surgical Comparator for Knee Cartilage Lesions and Osteoarthritis

NCT07339111
View directory record Official record
Conditions
Knee Cartilage Defects
Interventions
CARTISTEM® + Debridement, Debridement
Biological · Procedure
Lead sponsor
Medipost, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
20
States / cities
Birmingham, Alabama • Tempe, Arizona • El Cajon, California + 16 more
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Jul 22, 2026, 2:48 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Evaluation of Safety and Exploratory Efficacy of CARTISTEM®, a Cell Therapy Product for Articular Cartilage Defects

NCT01733186
View directory record Official record
Conditions
Degeneration Articular Cartilage Knee
Interventions
CARTISTEM®
Biological
Lead sponsor
Medipost, Inc.
Industry
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
2
States / cities
Chicago, Illinois • Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Jul 22, 2026, 2:48 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Longitudinal Assessment of Cartilage Injury and Remodeling After Anterior Cruciate Ligament Rupture and Reconstruction:

NCT03497780
View directory record Official record
Conditions
ACL - Anterior Cruciate Ligament Rupture, ACL Injury, Healthy
Interventions
Anterior cruciate ligament reconstruction
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 30 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
2
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 4, 2023 · Synced Jul 22, 2026, 2:48 PM EDT
Completed No phase listed Observational

Quantitative MRI of Glenohumeral Cartilage & Labrum in Shoulder Instability

NCT05431114
View directory record Official record
Conditions
Instability, Joint, Shoulder Dislocation, Shoulder Injuries, Shoulder Subluxation, Anterior Shoulder Instability, Glenoid; Dislocation
Interventions
MRI
Diagnostic Test
Lead sponsor
Duke University
Other
Eligibility
18 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 14, 2025 · Synced Jul 22, 2026, 2:48 PM EDT
Terminated Not applicable Interventional

Autologous Adipose-Derived Stromal Cells Delivered Intra-articularly in Patients With Osteoarthritis.

NCT01739504
View directory record Official record
Conditions
Osteoarthritis
Interventions
Liposuction with Local Anesthesia, Intra articular infusion of AD-SVF
Procedure · Biological
Lead sponsor
Ageless Regenerative Institute
Industry
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Aventura, Florida
Source: ClinicalTrials.gov public record
Updated Nov 23, 2017 · Synced Jul 22, 2026, 2:48 PM EDT
Terminated No phase listed Observational

IRF-PAI Functional Outcomes Data(With FIM Instrument Variables)

NCT01779037
View directory record Official record
Conditions
Heart and Blood Disease, Muscle, Bone and Cartilage Disease, Nervous System Diseases, Skin and Connective Tissue Disease, Wounds and Injuries
Interventions
Not listed
Lead sponsor
Uniform Data System for Medical Rehabilitation
Other
Eligibility
7 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2018
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated May 3, 2018 · Synced Jul 22, 2026, 2:48 PM EDT
Recruiting No phase listed Observational

Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry

NCT04536103
View directory record Official record
Conditions
Bone Diseases, Infectious, Musculoskeletal Diseases, Joint Diseases, Osteoarthritis, ACL Tear, Cartilage Degeneration
Interventions
MRI
Diagnostic Test
Lead sponsor
Xiaojuan Li
Other
Eligibility
18 Years to 50 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Jul 22, 2026, 2:48 PM EDT
Not listed Not applicable Interventional

Microfracture Versus Adipose Derived Stem Cells for the Treatment of Articular Cartilage Defects

NCT02090140
View directory record Official record
Conditions
Degenerative Lesion of Articular Cartilage of Knee
Interventions
ADSC Application, Microfracture
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 50 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2025
U.S. locations
3
States / cities
Redwood City, California • Santa Monica, California • Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 24, 2024 · Synced Jul 22, 2026, 2:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Study of Orthotic Shoe Inserts for Controlling Osteoarthritic Knee Pain

NCT00076453
View directory record Official record
Conditions
Osteoarthritis
Interventions
Lateral wedge orthotic shoe inserts, Standard orthotic shoe inserts
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
25 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2007
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 26, 2011 · Synced Jul 22, 2026, 2:48 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Senolytic Drugs Attenuate Osteoarthritis-Related Articular Cartilage Degeneration: A Clinical Trial

NCT04210986
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Fisetin, Placebo oral capsule
Dietary Supplement · Drug
Lead sponsor
Steadman Philippon Research Institute
Other
Eligibility
40 Years to 80 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Vail, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jul 22, 2026, 2:48 PM EDT
Not listed Not applicable Interventional

NuTech Affinity™ for the Treatment of Chondral Defects

NCT02837484
View directory record Official record
Conditions
Chondral Lesions, Cartilage
Interventions
NuTech Affinity™ Membrane
Other
Lead sponsor
NuTech Medical, Inc
Industry
Eligibility
18 Years to 55 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Jan 17, 2020 · Synced Jul 22, 2026, 2:48 PM EDT
Terminated Not applicable Interventional

Evaluation of the Auryzon Devices in the Optimization of Ear and Nose Reconstruction Procedures

NCT03624608
View directory record Official record
Conditions
Ear Deformities, Acquired, Ear; Deformity, Congenital, Microtia, Nose Deformity, Nose Deformities, Acquired, Nose; Deformity, Congenital, Nose; Deformity, Congenital, Bent or Squashed, Nose; Deformity, Syphilitic, Congenital, Nose; Deformity, Bone (Nose Cartilage), Nose; Deformity, Septum, Congenital, Nose; Deformity, Sinus (Wall), Congenital, Nose; Deformity, Syphilitic, Late (Etiology), Ear; Deformity, External, Ear; Deformity, Auricle, Ear, Acquired, Ear; Deformity, Auricle, Ear (Congenital)
Interventions
AuryzoN Family of Devices
Device
Lead sponsor
Reconstrata, LLC
Industry
Eligibility
Not listed
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 22, 2025 · Synced Jul 22, 2026, 2:48 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Treatment of Children With Obstructive Sleep Apnea and Laryngomalacia: the Role of Laser Supraglottoplasty

NCT00394550
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Respiration Disorders
Interventions
supraglottoplasty with laser
Procedure
Lead sponsor
Indiana University
Other
Eligibility
1 Year to 18 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2019
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 24, 2022 · Synced Jul 22, 2026, 2:48 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Autologous Chondrocyte Implantation in the Patellofemoral Joint

NCT00212849
View directory record Official record
Conditions
Chondrosis, Patellar Articular Cartilage Lesions, Trochlear Articular Cartilage Lesions
Interventions
Not listed
Lead sponsor
Orthopaedic Research Foundation
Other
Eligibility
18 Years to 50 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1995 – 2005
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 20, 2005 · Synced Jul 22, 2026, 2:48 PM EDT
Recruiting Not applicable Interventional

Cartilage Remodeling Using Low-Temperature Radiofrequency for Nasal Airway Reconstruction

NCT07032675
View directory record Official record
Conditions
Nasal Valve Collapse, Nose Enhancement
Interventions
Low-temperature radio-frequency reshaping of autologous cartilage nasal and/or auricular cartilage
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
6
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 30, 2025 · Synced Jul 22, 2026, 2:48 PM EDT
Completed No phase listed Observational

Correlation Between Trachebroncho Malacia/Hyperdynamic Airway Collapse And Obstructive Sleep Apnea

NCT02097212
View directory record Official record
Conditions
Trachebronchomalacia (TBM), Hyper Dynamic Airway Collapse (HDAC), Obstructive Sleep Apnea (OSA)
Interventions
Not listed
Lead sponsor
National Jewish Health
Other
Eligibility
18 Years to 80 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 28, 2017 · Synced Jul 22, 2026, 2:48 PM EDT
Completed No phase listed Observational

Prospective Registry of Anterior Cruciate Ligament Reconstructions

NCT04135950
View directory record Official record
Conditions
Anterior Cruciate Ligament Tear, Meniscal Tear, Cartilage Injury, Bone Bruising
Interventions
Not listed
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
Not listed
Enrollment
1,646 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2025
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Nov 19, 2025 · Synced Jul 22, 2026, 2:48 PM EDT