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ClinicalTrials.gov public records Last synced Jul 22, 2026, 1:37 AM EDT

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Showing 1–12 of 12 matching trials from the live ClinicalTrials.gov search.
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Conditions
Cartilage Injury, Knee Injuries, Arthropathy of Knee, Cartilage Damage, Knee Pain Swelling
Interventions
7 Tesla Magnetic Resonance Imaging Test
Diagnostic Test
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Houston, Texas
Conditions
Articular Cartilage Defects in the Knee Joint
Interventions
GelrinC, Microfracture historical control arm
Device · Other
Lead sponsor
Regentis Biomaterials
Industry
Eligibility
18 Years to 50 Years
Enrollment
181 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
13
States / cities
La Mesa, California • Orange, California • Denver, Colorado + 10 more
Conditions
Articular Cartilage Disorder, Degeneration; Articular Cartilage, Chronic Cartilage Injury, Acute Cartilage Injury, Defect of Articular Cartilage
Interventions
Neocartilage Implant/DeNovo® ET (Engineered Tissue Graft), Microfracture
Biological · Other
Lead sponsor
ISTO Technologies, Inc.
Industry
Eligibility
18 Years to 60 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2020
U.S. locations
9
States / cities
Los Angeles, California • Santa Monica, California • Chicago, Illinois + 5 more
Conditions
Knee Injury
Interventions
Anakinra
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 30 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Knee Osteoarthristis, Cartilage Damage, Platelet Rich Plasma, Platelet Rich Plasma Injection
Interventions
Platelet Rich Plasma, Emcyte PurePRP Supraphysiologic Concentrating System, APEX Biologix XCELL PRP System
Biological · Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
San Francisco, California
Conditions
Articular Cartilage Damage
Interventions
NeoCart, microfracture
Biological · Procedure
Lead sponsor
Histogenics Corporation
Industry
Eligibility
18 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2014
U.S. locations
6
States / cities
San Francisco, California • Bloomington, Minnesota • New York, New York + 3 more
Terminated No phase listed Observational Accepts healthy volunteers

ProChondrix® CR Articular Cartilage Restoration Evaluation (PACE) Registry

NCT04301258
Conditions
Cartilage Injury, Cartilage Damage
Interventions
Articular cartilage repair
Other
Lead sponsor
AlloSource
Industry
Eligibility
Not listed
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
5
States / cities
Mobile, Alabama • Wheat Ridge, Colorado • Washington D.C., District of Columbia + 2 more
Conditions
Cartilage Injury, Cartilage Damage
Interventions
Cryopreserved Osteochondral Allograft
Procedure
Lead sponsor
AlloSource
Industry
Eligibility
18 Years to 60 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
3
States / cities
Chicago, Illinois • Lexington, Kentucky • Cincinnati, Ohio
Terminated Phase 1Phase 2 Interventional Results available

Losartan to Improve Hip Microfracture

NCT04212650
Conditions
Hip Osteoarthritis, Hip Impingement Syndrome, Cartilage Damage, Fibrosis
Interventions
Losartan, Placebo
Drug · Other
Lead sponsor
Steadman Philippon Research Institute
Other
Eligibility
18 Years to 60 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Vail, Colorado
Completed No phase listed Observational Accepts healthy volunteers

MRI Markers of Cartilage Damage in Knee With Osteoarthritis

NCT00820430
Conditions
Osteoarthritis, Knee
Interventions
Magnetic Resonance Imaging
Other
Lead sponsor
American College of Radiology
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
5
States / cities
Hershey, Pennsylvania • Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania
Conditions
Knee Pain Chronic, Knee Osteoarthritis, Cartilage Damage, Cartilage Defects of the Knee, Cartilage or Osteochondral Defects in the Knee, Cartilage Lesion
Interventions
BioPoly, surgical standard of care (SSOC)
Device · Procedure
Lead sponsor
BioPoly LLC
Industry
Eligibility
30 Years to 65 Years
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
4
States / cities
Fort Wayne, Indiana • Indianapolis, Indiana • Rochester, Minnesota + 1 more
Conditions
Articular Cartilage Disorder of Knee, Cartilage Damage, Microfractures
Interventions
microfracture surgery + HST003
Biological
Lead sponsor
Histogen
Industry
Eligibility
18 Years to 50 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
5
States / cities
Vail, Colorado • Bradenton, Florida • Bethesda, Maryland + 2 more