- Conditions
- Injuries, Knee
- Interventions
- Single Portal Knee Arthroscopy, Two Portal Knee Arthroscopy
- Procedure
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- Winston-Salem, North Carolina
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Showing 25–48
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- Conditions
- Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, Knee Osteoarthritis, Osteo Arthritis Knee, Knee Injuries, Cartilage, Articular, Gait
- Interventions
- Real-time gait biofeedback, Sham real-time gait biofeedback
- Behavioral
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 16 Years to 35 Years
- Enrollment
- 70 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Microtia, Congenital, Microtia, Microtia-Anotia, Ear Deformities, Acquired, Ear Deformity External, Ear Malformation, Ear Cartilage
- Interventions
- Use of AuryzoN™ EAR 2.0 device, Hand carving
- Procedure
- Lead sponsor
- Nemours Children's Clinic
- Other
- Eligibility
- 5 Years to 20 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2030
- U.S. locations
- 1
- States / cities
- Orlando, Florida
- Conditions
- Sprain, Strain
- Interventions
- Ketoprofen Topical Patch 20%
- Drug
- Lead sponsor
- APR Applied Pharma Research s.a.
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2007
- U.S. locations
- 1
- States / cities
- Austin, Texas
- Conditions
- Meniscus Tear, Meniscus Lesion, Cartilage Injury
- Interventions
- Ceftriaxone, Placebo
- Drug · Other
- Lead sponsor
- Austin V Stone
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 5 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Lexington, Kentucky
- Conditions
- Articular Cartilage Defect Grade III or IV of the Knee
- Interventions
- Autologous Cell, Standard microfracture arthroscopic surgery
- Procedure
- Lead sponsor
- Fondren Orthopedic Group L.L.P.
- Other
- Eligibility
- 18 Years to 68 Years
- Enrollment
- 48 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2017
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Sprain, Strain, Acute Soft Tissue Injury
- Interventions
- Topical Ketoprofen 10% Cream, Topical Placebo Cream
- Drug
- Lead sponsor
- Imprimis Pharmaceuticals, Inc.
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 364 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2009
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, Knee Osteoarthritis, Knee Injuries, Cartilage, Articular, Gait
- Interventions
- Real-time gait biofeedback, Sham real-time gait biofeedback
- Behavioral
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 18 Years to 35 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Heart and Blood Disease, Muscle, Bone and Cartilage Disease, Nervous System Diseases, Skin and Connective Tissue Disease, Wounds and Injuries
- Interventions
- Not listed
- Lead sponsor
- Uniform Data System for Medical Rehabilitation
- Other
- Eligibility
- 7 Years to 100 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2018
- U.S. locations
- 1
- States / cities
- Buffalo, New York
- Conditions
- Articular Cartilage Damage
- Interventions
- NeoCart, microfracture
- Biological · Procedure
- Lead sponsor
- Histogenics Corporation
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2014
- U.S. locations
- 6
- States / cities
- San Francisco, California • Bloomington, Minnesota • New York, New York + 3 more
- Conditions
- Degenerative Lesion of Articular Cartilage of Knee
- Interventions
- ADSC Application, Microfracture
- Procedure
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 17 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2025
- U.S. locations
- 3
- States / cities
- Redwood City, California • Santa Monica, California • Denver, Colorado
- Conditions
- Knee Injury
- Interventions
- Placement of allograft CR Plug in primary injury site
- Procedure
- Lead sponsor
- RTI Surgical
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2012
- U.S. locations
- 3
- States / cities
- Los Angeles, California • Denver, Colorado • Indianapolis, Indiana
- Conditions
- Knee Injuries, Joint Surface Knee Lesions
- Interventions
- Marketed Product - MP01, Other Surgical Treatments
- Device · Procedure
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2034
- U.S. locations
- 6
- States / cities
- Parker, Colorado • Washington D.C., District of Columbia • Indianapolis, Indiana + 3 more
- Conditions
- Articular Cartilage Disorder, Degeneration; Articular Cartilage, Chronic Cartilage Injury, Acute Cartilage Injury, Defect of Articular Cartilage
- Interventions
- Chondrofix Osteochondral Allograft
- Procedure
- Lead sponsor
- Zimmer Orthobiologics, Inc.
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 29 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2014
- U.S. locations
- 5
- States / cities
- Cos Cob, Connecticut • New Haven, Connecticut • Greenwood, Indiana + 2 more
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout, Crohn Disease, Juvenile Idiopathic Arthritis, Lupus Erythematosus, Myositis, Osteoarthritis, Osteoporosis, Psoriasis, Psoriatic Arthritis, Scleroderma, Dermatomyositis, Inflammatory Bowel Diseases, Polymyositis, Axial Spondyloarthritis, Diffuse Idiopathic Skeletal Hyperostosis, Polymyalgia Rheumatica, Giant Cell Arteritis, Temporal Arteritis, Wegener, Relapsing Polychondritis, Undifferentiated Connective Tissue Disease, Spinal Cord Injuries, Alzheimer Disease, Amyotrophic Lateral Sclerosis, Ataxia, Bell Palsy, Brain Tumor, Cerebral Aneurysm, Epilepsy, Guillain-Barre Syndrome, Headache, Head Injury, Hydrocephalus, Lumbar Disc Disease, Meningitis, Multiple Sclerosis, Muscular Dystrophy, Neurocutaneous Syndromes, Parkinson Disease, Stroke, Cluster Headache, Tension-Type Headache, Chronic Obstructive Pulmonary Disease, Asthma, Lung Cancer, Cystic Fibrosis, Sleep Apnea, Eczema, Alopecia, Chronic Inflammation, Unstable Angina, Heart Attack, Heart Failure, Arrythmia, Valve Heart Disease, High Blood Pressure, Congenital Heart Disease, Peripheral Arterial Disease, Diabetes, Chronic Liver Disease, Obesity
- Interventions
- Not listed
- Lead sponsor
- Global Healthy Living Foundation
- Other
- Eligibility
- 19 Years and older
- Enrollment
- 40,000 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2025
- U.S. locations
- 1
- States / cities
- Upper Nyack, New York
- Conditions
- Defect of Articular Cartilage, Osteochondral Lesion of Talus, Osteochondritis Dissecans
- Interventions
- DeNovo NT Natural Tissue Graft
- Other
- Lead sponsor
- Zimmer Orthobiologics, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 205 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2019
- U.S. locations
- 8
- States / cities
- Sacramento, California • Honolulu, Hawaii • Baltimore, Maryland + 5 more
- Conditions
- Anterior Cruciate Ligament Tear, Meniscal Tear, Cartilage Injury, Bone Bruising
- Interventions
- Not listed
- Lead sponsor
- State University of New York at Buffalo
- Other
- Eligibility
- Not listed
- Enrollment
- 1,646 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2025
- U.S. locations
- 1
- States / cities
- Buffalo, New York
- Conditions
- Knee Injuries, Cartilage Injury, Cartilage Disease, Knee Discomfort
- Interventions
- Microfracture, Microfracture plus placement of Chondro-Gide® ACC
- Procedure · Device
- Lead sponsor
- Geistlich Pharma AG
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 82 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2025
- U.S. locations
- 3
- States / cities
- Phoenix, Arizona • Stamford, Connecticut • Johns Creek, Georgia
- Conditions
- Knee Injury
- Interventions
- CR Plug
- Other
- Lead sponsor
- RTI Surgical
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 9 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2012
- U.S. locations
- 4
- States / cities
- Birmingham, Alabama • Phoenix, Arizona • Englewood, Colorado + 1 more
- Conditions
- Cartilage Injury, Knee Injuries, Arthropathy of Knee, Cartilage Damage, Knee Pain Swelling
- Interventions
- 7 Tesla Magnetic Resonance Imaging Test
- Diagnostic Test
- Lead sponsor
- The Methodist Hospital Research Institute
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 112 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Meniscus Tears, Loose Bodies, Articular Osteoarthritis, Articular or Capsular Trauma
- Interventions
- VisionScope Imaging (VSI) Exam
- Procedure
- Lead sponsor
- VisionScope Technologies
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 105 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2013
- U.S. locations
- 7
- States / cities
- Los Angeles, California • Redwood City, California • Santa Monica, California + 4 more
- Conditions
- Knee Injuries, Joint Surface Knee Lesions
- Interventions
- Marketed Product - MP01, Surgical Standard of Care
- Device · Procedure
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- 21 Years to 75 Years
- Enrollment
- 170 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2030
- U.S. locations
- 1
- States / cities
- La Mesa, California
- Conditions
- Anterior Cruciate Ligament Rupture
- Interventions
- Initial graft tension during ACL reconstruction surgery
- Procedure
- Lead sponsor
- Rhode Island Hospital
- Other
- Eligibility
- 15 Years to 50 Years
- Enrollment
- 168 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2004 – 2024
- U.S. locations
- 2
- States / cities
- Providence, Rhode Island
- Conditions
- Acute Injury of Anterior Cruciate Ligament
- Interventions
- Not listed
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 13 Years to 70 Years
- Enrollment
- 89 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2017
- U.S. locations
- 1
- States / cities
- San Francisco, California