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ClinicalTrials.gov public records Last synced Oct 21, 2026, 1:35 PM EDT

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Showing 1–20 of 20 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Caseins Clear all
Completed Not applicable Interventional

A Study to Assess the Role of a Gluten Free-dairy Free (GFCF) Diet in the Dietary Management of Autism Associated Gastrointestinal Disorders

NCT01116388
View directory record Official record
Conditions
Autism, Gastrointestinal Symptoms
Interventions
GFCF product with GFCF diet, product containing gluten and casein (milk protein) with GFCF diet
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
2 Years to 17 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
2
States / cities
Boston, Massachusetts • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 8, 2015 · Synced Oct 21, 2026, 1:35 PM EDT
Completed Not applicable Interventional

Milk Beta Caseins on Digestive Discomfort, Gastric Emptying

NCT07884123
View directory record Official record
Conditions
Lactose Intolerants, Lactose Malabsorption, Caseins
Interventions
A1/A2 milk with oral naloxone, A1PF milk with oral naloxone
Other
Lead sponsor
Purdue University
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 21, 2026, 1:35 PM EDT
Completed Not applicable Interventional

Hydrolyzed Casein and Whey Protein Supplementation and the Addition of Leucine to Induce Protein Anabolism in Malnourished COPD Patients

NCT01154400
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Casein protein hydrolysates, Whey protein hydrolysates, Casein protein hydrolysates + LEU, Whey protein hydrolysates + LEU
Dietary Supplement
Lead sponsor
Texas A&M University
Other
Eligibility
45 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Oct 15, 2012 · Synced Oct 21, 2026, 1:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparing the Adaptation of Commercial Milk and A2 Milk in Lactose Maldigesters

NCT05669274
View directory record Official record
Conditions
Lactose Intolerance
Interventions
Milk containing A1 and A2 beta-casein, Milk containing only A2 beta-casein
Other
Lead sponsor
Purdue University
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 21, 2026, 1:35 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Extensively Hydrolyzed Formula Growth Monitioring Study (GMS)

NCT07513506
View directory record Official record
Conditions
Growth
Interventions
Extensively hydrolyzed casein formula (C-eHCF), commercially available, Extensively hydrolyzed casein formula (INV-eHCF)
Other
Lead sponsor
Mead Johnson Nutrition
Industry
Eligibility
10 Days to 14 Days
Enrollment
214 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
11
States / cities
Birmingham, Alabama • Jonesboro, Arkansas • Harbor Beach, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 21, 2026, 1:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Protein Blend Supplementation During Exercise Training on Muscle Growth and Strength

NCT01749189
View directory record Official record
Conditions
Muscle
Interventions
Blend, Whey, Placebo
Dietary Supplement
Lead sponsor
DuPont Nutrition and Health
Industry
Eligibility
18 Years to 35 Years · Male only
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 7, 2019 · Synced Oct 21, 2026, 1:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Eicosapentaenoic Acid and Protein Modulation to Induce Anabolism in Chronic Obstructive Pulmonary Disease (COPD): Aim 2

NCT01624792
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease, Muscle Wasting
Interventions
Olive oil, Fish oil, Fish oil and placebo
Dietary Supplement
Lead sponsor
Texas A&M University
Other
Eligibility
45 Years and older
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
College Station, Texas
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Oct 21, 2026, 1:35 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Nutritional and Dietary Treatment Study for Children/Adults With Autism

NCT02059577
View directory record Official record
Conditions
Autism
Interventions
Nutritional and Dietary Interventions
Dietary Supplement
Lead sponsor
Arizona State University
Other
Eligibility
30 Months to 60 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 11, 2014 · Synced Oct 21, 2026, 1:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Double Crossover Casein Type Tolerance Trial

NCT06315517
View directory record Official record
Conditions
Dairy Intolerance, Healthy Adults
Interventions
Conventional lactose-free cow's milk, Nonconventional (A2) cow's milk, Nonconventional (A2) lactose-free cow's milk
Other
Lead sponsor
Auburn University
Other
Eligibility
18 Years to 85 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 4, 2025 · Synced Oct 21, 2026, 1:35 PM EDT
Active, not recruiting Early Phase 1 Interventional Accepts healthy volunteers

Effects of Casein Protein on Metabolism When Taken Prior to Sleep and in the Morning

NCT06250270
View directory record Official record
Conditions
Metabolism
Interventions
protein or placebo
Dietary Supplement
Lead sponsor
Ohio University
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Athens, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 30, 2025 · Synced Oct 21, 2026, 1:35 PM EDT
Completed Not applicable Interventional

A1 Beta-casein-free Milk in Milk-intolerant Participants

NCT06763185
View directory record Official record
Conditions
Digestive Discomfort
Interventions
Dietary Supplement: conventional cow's milk consumption, and then A1PF milk consumption, Dietary Supplement: A1PF milk consumption, and then conventional cow's milk consumption
Other
Lead sponsor
a2 Milk Company Ltd.
Industry
Eligibility
18 Years to 68 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Jan 8, 2025 · Synced Oct 21, 2026, 1:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Protein Blends (Soy, Whey and Casein) for Muscle Synthesis

NCT01358305
View directory record Official record
Conditions
Muscle Synthesis
Interventions
Protein Blend
Other
Lead sponsor
DuPont Nutrition and Health
Industry
Eligibility
18 Years to 35 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 7, 2019 · Synced Oct 21, 2026, 1:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Infants Fed Extensively Hydrolyzed Casein-Based Infant Formulas

NCT04006236
View directory record Official record
Conditions
Infant Development
Interventions
Experimental Infant Formula, Control Infant Formula
Other
Lead sponsor
Abbott Nutrition
Industry
Eligibility
0 Days to 14 Days
Enrollment
245 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
17
States / cities
Phoenix, Arizona • Tucson, Arizona • College Park, Georgia + 14 more
Source: ClinicalTrials.gov public record
Updated Sep 24, 2021 · Synced Oct 21, 2026, 1:35 PM EDT
Completed Phase 1 Interventional

Diet and Behavior in Young Children With Autism

NCT00090428
View directory record Official record
Conditions
Autism, Autistic Disorder
Interventions
Gluten- and casein-free diet, Placebo controlled diet
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
30 Months to 54 Months
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Feb 1, 2013 · Synced Oct 21, 2026, 1:35 PM EDT
Completed Not applicable Interventional Results available

Double-Blind Trial of a Probiotic Supplement to Reduce the Symptoms of Schizophrenia

NCT01242371
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder
Interventions
Probiotic Supplement, Identical-appearing Placebo
Dietary Supplement
Lead sponsor
Sheppard Pratt Health System
Other
Eligibility
18 Years to 65 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Towson, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 5, 2019 · Synced Oct 21, 2026, 1:35 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Assessing the Presence of Casomorphins in Human Plasma After Dairy Ingestion

NCT00360919
View directory record Official record
Conditions
Food Habits
Interventions
cheese ingestion
Behavioral
Lead sponsor
Physicians Committee for Responsible Medicine
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Aug 7, 2012 · Synced Oct 21, 2026, 1:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparing the Gastric Transit of Commercial Milk and A2 Milk

NCT05658861
View directory record Official record
Conditions
Lactose Intolerance, Adult Type
Interventions
Milk containing A1 and A2 beta-casein, Milk containing only A2 beta-casein
Other
Lead sponsor
Purdue University
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 21, 2023 · Synced Oct 21, 2026, 1:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Casein Protein and Leucine Supplementation in Chronic Obstructive Pulmonary Disease (COPD)

NCT01734473
View directory record Official record
Conditions
COPD
Interventions
Hydrolyzed casein protein, Hydrolyzed casein protein + carbohydrates, Hydrolyzed casein protein + leucine, Hydrolyzed casein protein + carbohydrates + leucine, 4 levels of hydrolyzed casein protein + carbohydrates
Dietary Supplement
Lead sponsor
Texas A&M University
Other
Eligibility
45 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
College Station, Texas
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Oct 21, 2026, 1:35 PM EDT
Completed Not applicable Interventional

Comparing the Digestion of Milk With Different Beta-casein Protein Content by Dairy Intolerant Persons

NCT03713346
View directory record Official record
Conditions
Dairy Intolerance
Interventions
Lactose free milk, Jersey milk, High A1 β-casein milk, High A2 β-casein milk
Other
Lead sponsor
Purdue University
Other
Eligibility
18 Years to 65 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 8, 2021 · Synced Oct 21, 2026, 1:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Casein Timing on Body Composition and Performance

NCT03352583
View directory record Official record
Conditions
Body Composition
Interventions
Protein
Dietary Supplement
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Denton, Texas
Source: ClinicalTrials.gov public record
Updated Nov 24, 2017 · Synced Oct 21, 2026, 1:35 PM EDT