- Conditions
- Catheter-Related Infections
- Interventions
- Mino-Lok Therapy (MLT)
- Drug
- Lead sponsor
- Leonard-Meron Biosciences, Inc.
- Industry
- Eligibility
- 12 Years and older
- U.S. locations
- 27
- States / cities
- Phoenix, Arizona • New Haven, Connecticut • Washington D.C., District of Columbia + 21 more
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Showing 1–24
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- Conditions
- Urinary Tract Infections, Catheter-Related Infections
- Interventions
- methenamine hippurate, Ciprofloxacin
- Drug
- Lead sponsor
- University of Pennsylvania
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 201 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2020
- U.S. locations
- 4
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Catheter Related Infections, Short Bowel Syndrome
- Interventions
- 70% ethanol
- Drug
- Lead sponsor
- Boston Children's Hospital
- Other
- Eligibility
- 3 Months and older
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Catheter-related Bloodstream Infection
- Interventions
- Chlorhexidine-impregnated foam dressing
- Device
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1,088 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2009
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Cervical Cancer, Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Precancerous/Nonmalignant Condition, Unspecified Adult Solid Tumor, Protocol Specific, Veno-occlusive Disease
- Interventions
- Fragmin, placebo
- Drug · Other
- Lead sponsor
- Jonsson Comprehensive Cancer Center
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2000
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Catheter-related Bloodstream Infection (CRBSI) Nos, Bloodstream Infection Due to Central Venous Catheter, Bloodstream Infection Due to Hickman Catheter
- Interventions
- Ethanol, Heparin Lock, Normal Saline
- Drug
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 39 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Urinary Tract Infections, Catheter Infection, Catheter-Related Infections
- Interventions
- Catheter insertion with Povidone Iodine, Standard of care catheter insertion
- Drug · Procedure
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 18 Years to 89 Years · Female only
- Enrollment
- 99 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Urinary Retention, Urinary Tract Infections
- Interventions
- Tamsulosin, Placebo
- Drug
- Lead sponsor
- University of Wisconsin, Madison
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 158 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2018
- U.S. locations
- 1
- States / cities
- Madison, Wisconsin
- Conditions
- Catheter-Related Fungal Infections
- Interventions
- Micafungin lock therapy
- Drug
- Lead sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- NIH
- Eligibility
- 6 Months to 18 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2008
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Infection Associated With Catheter, Bacteremia, Sepsis
- Interventions
- Ethanol lock, Heparinized saline
- Drug
- Lead sponsor
- East Carolina University
- Other
- Eligibility
- Up to 32 Weeks
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2010
- U.S. locations
- 1
- States / cities
- Greenville, North Carolina
- Conditions
- Catheter-related Bloodstream Infection
- Interventions
- SQ53 Wipe, Ethanol Wipe
- Device
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 59 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Sepsis, Bacteremia, Fungemia
- Interventions
- MBI 226
- Drug
- Lead sponsor
- BioWest Therapeutics Inc
- Industry
- Eligibility
- 16 Years and older
- Enrollment
- 1,400 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2000 – 2003
- U.S. locations
- 1
- States / cities
- Lake Bluff, Illinois
- Conditions
- Staphylococcal Infections
- Interventions
- Tigecycline
- Drug
- Lead sponsor
- CPL Associates
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2008
- U.S. locations
- 3
- States / cities
- Huntsville, Alabama • Marietta, Georgia • Cumberland, Maryland
- Conditions
- Catheter-Associated Infections, Catheter-Related Infections
- Interventions
- Nitroglycerin-citrate-ethanol (NiCE)
- Drug
- Lead sponsor
- Novel Anti-Infective Technologies, LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Bacteremia
- Interventions
- dalbavancin
- Drug
- Lead sponsor
- Vicuron Pharmaceuticals
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 88 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2003
- U.S. locations
- 1
- States / cities
- Marietta, Georgia
- Conditions
- Children in the Pediatric Intensive Care Unit or General Pediatric Care Unit Requiring a Central Venous Catheter
- Interventions
- Cook Spectrum Pediatric Central Venous Catheter Anti-microbial Impregnated Polyurethane and Arrow Pediatric Central Venous Catheter
- Device
- Lead sponsor
- Corewell Health West
- Other
- Eligibility
- Up to 18 Years
- Enrollment
- 500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2005
- U.S. locations
- 1
- States / cities
- Grand Rapids, Michigan
- Conditions
- Catheter Related Infections
- Interventions
- The Integra External Drainage Catheter., The Ventriclear EVD Antibiotic Catheter, The Codman Bactiseal EVD Catheter Set
- Device
- Lead sponsor
- University of Oklahoma
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- Oklahoma City, Oklahoma
- Conditions
- Bacterial Infections
- Interventions
- Central Venous Catheter
- Device
- Lead sponsor
- Angiotech Pharmaceuticals
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 960 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2007
- U.S. locations
- 21
- States / cities
- Birmingham, Alabama • Orange, California • San Diego, California + 17 more
- Conditions
- Catheter-Related Infections
- Interventions
- 25% ethanol, heparin lock
- Drug · Other
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 6 Months to 21 Years
- Enrollment
- 16 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2014
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- End-Stage Renal Disease, Hemodialysis Catheter-associated Infection
- Interventions
- catheter lock solution consisting of N-acetylcystein, tigecycline and heparin
- Drug
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years to 100 Years
- Enrollment
- 18 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2009
- U.S. locations
- 3
- States / cities
- Houston, Texas
- Conditions
- Urinary Tract Infections
- Interventions
- Not listed
- Lead sponsor
- Children's Mercy Hospital Kansas City
- Other
- Eligibility
- 1 Day to 17 Years
- Enrollment
- 321 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2011
- U.S. locations
- 1
- States / cities
- Kansas City, Missouri
- Conditions
- Intestinal Failure, CRBSI - Catheter Related Bloodstream Infection
- Interventions
- Sodium bicarb lock
- Drug
- Lead sponsor
- Riad Rahhal
- Other
- Eligibility
- 1 Year to 18 Years
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa
- Conditions
- Vascular Access Complication, Vascular Access Related Infection
- Interventions
- Arrow PICC with Chloragard Technology
- Device
- Lead sponsor
- Teleflex
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 2
- States / cities
- Lexington, Kentucky • Detroit, Michigan
- Conditions
- Bacteremia, Gram-Positive Bacterial Infections
- Interventions
- Cefazolin IV, Linezolid IV, Vancomycin (IV)
- Drug
- Lead sponsor
- Pfizer
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 61 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2006
- U.S. locations
- 3
- States / cities
- Baltimore, Maryland