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Showing 1–24 of 33 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cefazolin Clear all
Not listed Phase 4 Interventional Accepts healthy volunteers

Vascular Surgical Antibiotic Prophylaxis Study (VSAPS 2)

NCT01612052
View directory record Official record
Conditions
MRSA - Methicillin Resistant Staphylococcus Aureus Infection
Interventions
Antibiotic Prophylaxis
Drug
Lead sponsor
CAMC Health System
Other
Eligibility
18 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Charleston, West Virginia
Source: ClinicalTrials.gov public record
Updated Feb 19, 2013 · Synced Jul 21, 2026, 4:04 PM EDT
Not listed Phase 1 Interventional

Safety and Therapeutic Drug Monitoring of Cefazolin in Continuous Renal Replacement Therapy

NCT03672149
View directory record Official record
Conditions
Renal Replacement Therapy, Pharmacokinetics
Interventions
Cefazolin
Drug
Lead sponsor
Drexel University
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 18, 2020 · Synced Jul 21, 2026, 4:04 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Vancomycin and Daptomycin Plus Cefazolin for Preoperative Vascular Surgery Prophylaxis

NCT00967941
View directory record Official record
Conditions
MRSA Infections
Interventions
Not listed
Lead sponsor
CAMC Health System
Other
Eligibility
18 Years to 90 Years
Enrollment
169 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
Charleston, West Virginia
Source: ClinicalTrials.gov public record
Updated Feb 27, 2020 · Synced Jul 21, 2026, 4:04 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Pharmacokinetics and Safety of Cefazolin 2g in DUPLEX

NCT01121354
View directory record Official record
Conditions
Infection
Interventions
Cefazolin 2g for Injection USP and Dextrose Injection USP, Cefazolin 1.5g
Drug
Lead sponsor
B. Braun Medical Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 15, 2013 · Synced Jul 21, 2026, 4:04 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Peri-operative Cefazolin Prophylaxis at Time of Cesarean Delivery in the Obese Gravida

NCT01904500
View directory record Official record
Conditions
Obesity, Pregnancy
Interventions
Pre-operative cefazolin
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 17, 2014 · Synced Jul 21, 2026, 4:04 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Trial Comparing the Optimal Timing of Antibiotic Prophylaxis at the Time of Cesarean Delivery

NCT00811603
View directory record Official record
Conditions
Cesarean Section, Infection
Interventions
Cefazolin (Timing of Antibiotic Prophylaxis)
Drug
Lead sponsor
MemorialCare
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
2
States / cities
Long Beach, California • Orange, California
Source: ClinicalTrials.gov public record
Updated Sep 17, 2009 · Synced Jul 21, 2026, 4:04 PM EDT
Completed No phase listed Observational

Study of Drug Concentration of Ondansetron and Cefazolin in Mothers and Neonates

NCT01357369
View directory record Official record
Conditions
Pregnancy Complications
Interventions
Phlebotomy
Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Apr 20, 2016 · Synced Jul 21, 2026, 4:04 PM EDT
Terminated Phase 3 Interventional Results available

Linezolid in the Treatment of Hemodialysis Patients With Catheter-Related Gram-Positive Bloodstream Infections

NCT00108433
View directory record Official record
Conditions
Bacteremia, Gram-Positive Bacterial Infections
Interventions
Cefazolin IV, Linezolid IV, Vancomycin (IV)
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
3
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 6, 2012 · Synced Jul 21, 2026, 4:04 PM EDT
Terminated Phase 4 Interventional Results available

Safety of 1 g and 2 g of Cefazolin in Pediatric Subjects

NCT03231228
View directory record Official record
Conditions
Postoperative Infection
Interventions
Cefazolin 1 g Infusion, Cefazolin 2 g Infusion
Drug
Lead sponsor
B. Braun Medical Inc.
Industry
Eligibility
10 Years to 17 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
5
States / cities
Little Rock, Arkansas • Columbia, Missouri • Dallas, Texas + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2020 · Synced Jul 21, 2026, 4:04 PM EDT
Completed Not applicable Interventional

Pharmacokinetics of Bolus Versus Continuous Cefazolin Infusion in Patients Undergoing Major Surgery

NCT02058979
View directory record Official record
Conditions
Plasma Concentration of Antibiotics
Interventions
BOLUS INFUSION (Ancef), CONTINUOUS INFUSION (Ancef)
Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 25, 2016 · Synced Jul 21, 2026, 4:04 PM EDT
Completed Not applicable Interventional

Subcutaneous Injection and Ultrasonic Dispersion of Cefazolin Into Chronic Pelvic-Region Pressure Ulcers in Persons With Spinal Cord Injury

NCT02584426
View directory record Official record
Conditions
Spinal Cord Injury, Chronic Pressure Ulcers
Interventions
Ultrasonic Distribution of Cefazolin
Device
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 79 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 24, 2022 · Synced Jul 21, 2026, 4:04 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Pharmacokinetics and Safety of Cefazolin 3gm DUPLEX in Adults

NCT05205486
View directory record Official record
Conditions
Infections
Interventions
Cefazolin 3gm for Injection USP and Dextrose Injection USP
Drug
Lead sponsor
B. Braun Medical Inc.
Industry
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
2
States / cities
Columbus, Georgia • Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Feb 27, 2025 · Synced Jul 21, 2026, 4:04 PM EDT
Terminated Phase 4 Interventional

Noninferiority Comparison of Prophylactic Open Fracture Antimicrobial Regimens

NCT03560232
View directory record Official record
Conditions
Open Fracture, Post-Op Wound Infection
Interventions
Ceftriaxone, Ampicillin/sulbactam, Piperacillin/tazobactam, Cefazolin + Gentamicin, Clindamycin + Gentamicin
Drug
Lead sponsor
Mercy Health Ohio
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
2
States / cities
Warren, Ohio • Youngstown, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 10, 2020 · Synced Jul 21, 2026, 4:04 PM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Azithromycin to Improve Latency in Exam Indicated Cerclage Control Trial

NCT05132829
View directory record Official record
Conditions
Preterm Birth, Obstetric Labor, Premature, Obstetric Labor Complications, Pregnancy Complications, Physiological Effects of Drugs, Uterine Cervical Incompetence, Anti-Bacterial Agents, Azithromycin, Cefazolin
Interventions
Azithromycin 1 gram IV, Cefazolin and indomethacin
Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
2
States / cities
Chicago, Illinois • New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 25, 2023 · Synced Jul 21, 2026, 4:04 PM EDT
No Longer Available No phase listed Expanded access Accepts healthy volunteers

Direct Antibiotic Delivery of Cefazolin Into Soft Tissue Infections Using Subcutaneous Injection and Ultrasonic Dispersion

NCT01238276
View directory record Official record
Conditions
Infection, Soft Tissue, Infection, Wound, Cellulitis, Diabetic Foot Ulcer
Interventions
Cefazolin, Silberg Tissue Preparation System
Drug · Device
Lead sponsor
Sonescence, Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
U.S. locations
1
States / cities
Sebastopol, California
Source: ClinicalTrials.gov public record
Updated Oct 22, 2018 · Synced Jul 21, 2026, 4:04 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Cefazolin PK Study 3g vs 2g

NCT05309304
View directory record Official record
Conditions
Healthy
Interventions
Cefazolin
Drug
Lead sponsor
Baxter Healthcare Corporation
Industry
Eligibility
18 Years to 55 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 11, 2022 · Synced Jul 21, 2026, 4:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

PROPHYLACTIC ANTIBIOTICS PRIOR TO CESAREAN SECTION IN OBESE WOMEN

NCT01810354
View directory record Official record
Conditions
Infection Prevention
Interventions
Cefazolin
Drug
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
Female only
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 23, 2014 · Synced Jul 21, 2026, 4:04 PM EDT
Enrolling by invitation Phase 4 Interventional

Efficacy and Safety of Intraosseous Antibiotic Prophylaxis in Total Hip Replacement

NCT07549542
View directory record Official record
Conditions
Antibiotic Prophylaxis Surgery
Interventions
CeFAZolin 1000 MG, Saline (0.9%, sterile, for infusion)
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Somerset, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Jul 21, 2026, 4:04 PM EDT
Completed Phase 4 Interventional Results available

Skeletal Muscle and Adipose Tissue Study

NCT03190668
View directory record Official record
Conditions
Idiopathic Scoliosis
Interventions
Bolus dose of Cefazolin, Continuous Cefazolin drip, Paraspinal muscle microdialysis catheters, Subcutaneous microdialysis catheters
Drug · Device
Lead sponsor
University of Florida
Other
Eligibility
12 Years to 20 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 10, 2023 · Synced Jul 21, 2026, 4:04 PM EDT
Completed Phase 4 Interventional Results available

Serum and Tissue Cefazolin Concentrations in Patients Undergoing Cesarean Delivery

NCT01755026
View directory record Official record
Conditions
Cesarean Delivery, Wound Infection, Obesity
Interventions
cefazolin
Drug
Lead sponsor
Michael Stitely
Other
Eligibility
18 Years and older · Female only
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Aug 20, 2013 · Synced Jul 21, 2026, 4:04 PM EDT
Withdrawn Phase 4 Interventional

Comparison Study of Cefazolin Versus Cefazolin Plus Azithromycin Prophylaxis in Post-Cesarean Endometritis

NCT01721616
View directory record Official record
Conditions
Endometritis
Interventions
Azithromycin, Cefazolin
Drug
Lead sponsor
University of Missouri, Kansas City
Other
Eligibility
Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated May 4, 2015 · Synced Jul 21, 2026, 4:04 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Supracondylar Pinning Antibiotic Stewardship (SPAS) Trial

NCT04288206
View directory record Official record
Conditions
Supracondylar Humerus Fracture, Infection
Interventions
Cefazolin, normal saline
Drug
Lead sponsor
Legacy Health System
Other
Eligibility
0 Years to 18 Years
Enrollment
1,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 11, 2022 · Synced Jul 21, 2026, 4:04 PM EDT
Completed Phase 4 Interventional

Comparison of a Morphomic-Based to the Standard-of-Care-Based Cefazolin Dose for Antimicrobial Prophylaxis

NCT06005168
View directory record Official record
Conditions
Surgical Prophylaxis
Interventions
Cefazolin for Injection
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Jul 21, 2026, 4:04 PM EDT
Withdrawn Phase 4 Interventional

Adequacy of Perioperative Cefazolin for Surgery Antibiotic Prophylaxis in Obese Patients

NCT01886742
View directory record Official record
Conditions
Obesity
Interventions
Standard Dose Group, Weight Based Group
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 5, 2017 · Synced Jul 21, 2026, 4:04 PM EDT