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ClinicalTrials.gov public records Last synced Oct 13, 2026, 11:36 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 73–96 of 296 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Central Adiposity Clear all
Completed No phase listed Observational

Association of Genes to Resistance to Weight Loss in Obese Patients

NCT00858221
View directory record Official record
Conditions
Obesity, Metabolic Syndrome, Dyslipidemia
Interventions
Not listed
Lead sponsor
Interleukin Genetics, Inc.
Industry
Eligibility
21 Years to 70 Years
Enrollment
824 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 20, 2009 · Synced Oct 13, 2026, 11:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family-Centered Diabetes Project - Sharing Wisdom

NCT00438126
View directory record Official record
Conditions
Prediabetes, Metabolic Syndrome, Overweight, Obesity
Interventions
A lifestyle educational program
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 40 Years · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2006
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Mar 2, 2010 · Synced Oct 13, 2026, 11:36 AM EDT
Not yet recruiting Phase 2 Interventional

Safety and Efficacy of NA-931 and Tirzepatide in Adults Who Are Overweight or Obese

NCT06732245
View directory record Official record
Conditions
Obesity and Overweight
Interventions
NA-931, Tirzepatide, NA-931 150 mg + no Tirzepatide
Drug
Lead sponsor
Biomed Industries, Inc.
Industry
Eligibility
19 Years to 80 Years
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
8
States / cities
Los Angeles, California • San Diego, California • San Francisco, California + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 13, 2026, 11:36 AM EDT
Recruiting Not applicable Interventional

Community Connections Through Native Hawaiian Cultural Values to Strengthen Youth Resilience, Health, and Well-Being

NCT07536256
View directory record Official record
Conditions
Chronic Disease, Adolescent Asthma, Obesity & Overweight, Youth Mental Health, Youth Obesity, Prediabetes, Asthma
Interventions
Community Referral to Kaiona Programs
Behavioral
Lead sponsor
Waianae Coast Comprehensive Health Center
Other
Eligibility
12 Years to 25 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Waianae, Hawaii
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 13, 2026, 11:36 AM EDT
Completed Phase 2 Interventional

Safety and Benefit of MBX-8025 With and Without Commonly Used Statins in Moderately Overweight Patients With High Cholesterol

NCT00701883
View directory record Official record
Conditions
Hyperlipidemia
Interventions
Placebo, MBX-8025, Atorvastatin
Drug
Lead sponsor
Gilead Sciences
Industry
Eligibility
18 Years to 75 Years
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
28
States / cities
Birmingham, Alabama • Phoenix, Arizona • Huntington Beach, California + 24 more
Source: ClinicalTrials.gov public record
Updated Jun 12, 2015 · Synced Oct 13, 2026, 11:36 AM EDT
Completed No phase listed Observational

Johns Hopkins Weight Management Center Patient Data

NCT03321565
View directory record Official record
Conditions
Obesity
Interventions
Behavioral counseling and optional meal replacement program
Other
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years and older
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1990 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 10, 2021 · Synced Oct 13, 2026, 11:36 AM EDT
Not listed Not applicable Interventional

Efficacy of IV Acetaminophen in Acute Post-Operative Pain Control in Laparoscopic Roux-en-Y Gastric Bypass Surgery (LRYGBP) Patients

NCT01460667
View directory record Official record
Conditions
Morbid Obesity
Interventions
IV acetaminophen, IV normal saline
Drug
Lead sponsor
McLaren Regional Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
1
States / cities
Flint, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 27, 2011 · Synced Oct 13, 2026, 11:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Almased Multi-Center Diabetes Intervention Trial

NCT01702012
View directory record Official record
Conditions
Type 2 Diabetes, Obesity
Interventions
Almased Meal Replacement Powder, Group-Based Lifestyle Intervention
Dietary Supplement · Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years and older
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 31, 2020 · Synced Oct 13, 2026, 11:36 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Retrospective Chart Review of the 5 & 2 & 2 and 4 & 2 & 1 Plans

NCT02150837
View directory record Official record
Conditions
Obesity
Interventions
5 & 2 & 2 Plan, 4 & 2 & 1 Plan
Other
Lead sponsor
Medifast, Inc.
Industry
Eligibility
18 Years and older
Enrollment
372 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Owings Mills, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 13, 2019 · Synced Oct 13, 2026, 11:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Multicenter Endoscopic Sleeve Gastrectomy (ESG) Trial (MERIT Trial)

NCT03406975
View directory record Official record
Conditions
Obesity, Hypertension, Diabetes Mellitus, Type 2
Interventions
Overstitch Endoscopic Suture System, Lifestyle Intervention
Device · Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years to 65 Years
Enrollment
208 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
9
States / cities
Orlando, Florida • Chicago, Illinois • Evanston, Illinois + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 18, 2022 · Synced Oct 13, 2026, 11:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Behavioral Weight Loss as a Treatment for Migraine in Obese Women

NCT01197196
View directory record Official record
Conditions
Migraine, Obesity
Interventions
Behavioral Weight Loss Intervention, Migraine Education
Behavioral · Other
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 31, 2021 · Synced Oct 13, 2026, 11:36 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Identifying Genes That May Increase the Risk for Heart Disease in African Americans

NCT00344136
View directory record Official record
Conditions
Heart Diseases
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
21 Years to 95 Years
Enrollment
5,302 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2004
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Jul 29, 2016 · Synced Oct 13, 2026, 11:36 AM EDT
Not listed Not applicable Interventional

Impact of a Ketogenic Diet on Metabolic and Psychiatric Health in Patients With Bipolar Illness

NCT05705063
View directory record Official record
Conditions
Bipolar Disorder I, Bipolar II Disorder, Bipolar I Disorder, Bipolar Disorder, Bipolar Depression, Bipolar and Related Disorders, Bipolar Disorder, Type 1, Bipolar Disorder, Type 2, Bipolar Disorder, Mixed, Obesity, Metabolic Syndrome, Ketogenic Dieting, Weight Gain, Brain Metabolic Disorder, Psychotropic Agents Causing Adverse Effects in Therapeutic Use
Interventions
LCHF Ketogenic Diet
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jan 30, 2023 · Synced Oct 13, 2026, 11:36 AM EDT
Completed Not applicable Interventional

The Hypothalamic-Pituitary-Adrenal (HPA) Axis as an Effector System in Weight Regulation

NCT00688987
View directory record Official record
Conditions
Obesity, Addison's Disease
Interventions
Hydrocortisone, Isocaloric Diet
Drug · Dietary Supplement
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2004
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 5, 2008 · Synced Oct 13, 2026, 11:36 AM EDT
Completed Not applicable Interventional

Effectiveness of Patient-centered Community Health Worker Support to Help Patients Control Chronic Disease

NCT01900470
View directory record Official record
Conditions
Obesity, Diabetes, Hypertension, Asthma/COPD With Tobacco Dependence
Interventions
CHW Goal Support
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
Not listed
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 3, 2017 · Synced Oct 13, 2026, 11:36 AM EDT
Completed No phase listed Observational

Primary Care, Communication, and Improving Children's Health

NCT02277899
View directory record Official record
Conditions
Childhood Obesity, Overweight, Communication, Weight Loss
Interventions
Communication regarding overweight status, Risk-factor assessment and counseling, Lifestyle behavior assessment and counseling, Interval follow-up to readdress weight, Patient-centered communication
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
6 Years to 12 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 19, 2020 · Synced Oct 13, 2026, 11:36 AM EDT
Not yet recruiting Not applicable Interventional

ENLIGHT Trial: ESG With Fundal Mucosal Ablation

NCT07792226
View directory record Official record
Conditions
Obesity, Obesity (Body Mass Index >30 kg/m2)
Interventions
Endoscopic Sleeve Gastroplasty (ESG), Fundal Mucosal Ablation
Procedure
Lead sponsor
West Virginia University
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 13, 2026, 11:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Eon™ FR 1064 Full Abdomen Clinical Study Protocol

NCT04842110
View directory record Official record
Conditions
Abdominal Obesity
Interventions
Experimental: eonTM FR 1064 nm device
Device
Lead sponsor
Dominion Aesthetic Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Altamonte Springs, Florida
Source: ClinicalTrials.gov public record
Updated Apr 13, 2021 · Synced Oct 13, 2026, 11:36 AM EDT
Recruiting Not applicable Interventional

Feasibility of a Nutrition Intervention for Patients With Prediabetes at a Federally Qualified Health Center

NCT06897982
View directory record Official record
Conditions
Prediabetic State, PreDiabetes, Health Knowledge, Attitudes, Practice, Nutrition, Healthy, Acceptability of Health Care, Obesity Prevention
Interventions
One-arm feasibility pilot of a nutrition intervention to recruit, engage, and retain DPP participants in the safety-net setting in Los Angeles
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 99 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 13, 2026, 11:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Community Outreach - Obesity Prevention Trial (CO-OPT)

NCT02024360
View directory record Official record
Conditions
Obesity, Overweight, Children
Interventions
Patient navigation
Behavioral
Lead sponsor
Denver Health and Hospital Authority
Other
Eligibility
2 Years to 6 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Oct 13, 2026, 11:36 AM EDT
Suspended Not applicable Interventional

Bariatric Embolization of Arteries in Obese Patients With HCC to Allow Salvage Liver Transplantation

NCT02935478
View directory record Official record
Conditions
Obesity, Weight Loss, Body Weight, Hepatocellular Carcinoma, HCC, Hepatitis C, Cirrhosis
Interventions
Embospheres Microspheres
Device
Lead sponsor
St. Louis University
Other
Eligibility
18 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 6, 2025 · Synced Oct 13, 2026, 11:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Primary Care Pediatrics Learning Activity and Nutrition With Families

NCT02873715
View directory record Official record
Conditions
Pediatric Obesity
Interventions
Family-based treatment, Usual Care
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
6 Years and older
Enrollment
1,010 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
4
States / cities
St Louis, Missouri • Buffalo, New York • Rochester, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 26, 2024 · Synced Oct 13, 2026, 11:36 AM EDT
Completed Phase 2 Interventional

A Study of Enicepatide (CT-388) in Participants With Obesity or Overweight With at Least One Weight-Related Comorbidity

NCT06525935
View directory record Official record
Conditions
Obesity, Overweight
Interventions
Placebo, Enicepatide
Drug
Lead sponsor
Carmot Therapeutics, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
469 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
34
States / cities
Birmingham, Alabama • Homewood, Alabama • Mesa, Arizona + 29 more
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 13, 2026, 11:36 AM EDT
Completed Not applicable Interventional

New Media Obesity Treatment in Community Health Centers

NCT01827800
View directory record Official record
Conditions
Obesity
Interventions
eHealth weight loss intervention
Behavioral
Lead sponsor
Duke University
Other
Eligibility
21 Years and older
Enrollment
351 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 13, 2018 · Synced Oct 13, 2026, 11:36 AM EDT