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ClinicalTrials.gov public records Last synced Oct 14, 2026, 2:46 PM EDT

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Showing 169–192 of 296 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Central Adiposity Clear all
Recruiting Phase 2 Interventional

Efficacy and Safety of Phentermine/Topiramate in Youth With Hypothalamic Obesity

NCT06299891
View directory record Official record
Conditions
Hypothalamic Obesity, Hypothalamic Tumor, Craniopharyngioma
Interventions
Phentermine / Topiramate Extended Release Oral Capsule [Qsymia], Placebo
Drug · Other
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
6 Years to 28 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 28, 2025 · Synced Oct 14, 2026, 2:46 PM EDT
Completed Phase 3 Interventional Results available

Safety and Effectiveness Study of The Swedish Adjustable Gastric Band (SAGB) in the Treatment of Morbid Obesity

NCT00166205
View directory record Official record
Conditions
Obesity, Morbid
Interventions
Swedish Adjustable Gastric Band
Device
Lead sponsor
Ethicon Endo-Surgery
Industry
Eligibility
18 Years to 60 Years
Enrollment
276 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
12
States / cities
Los Angeles, California • San Diego, California • Fort Lauderdale, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2015 · Synced Oct 14, 2026, 2:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

SDSU MOVE/Me Muevo Project

NCT00381069
View directory record Official record
Conditions
Childhood Obesity
Interventions
Family & Community Recreation Center Intervention
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
5 Years to 10 Years
Enrollment
541 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 30, 2024 · Synced Oct 14, 2026, 2:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Healthy Families: Transforming Care for Obese Children at NYU Lutheran Family Health Centers

NCT02817009
View directory record Official record
Conditions
Childhood Obesity
Interventions
Social Support, Nutrition Session, Physical Activity Session
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
9 Years to 11 Years
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Sep 21, 2016 · Synced Oct 14, 2026, 2:46 PM EDT
Active, not recruiting Phase 4 Interventional

A Study of a Novel Precision Medicine Approach For Obesity

NCT06814938
View directory record Official record
Conditions
Obesity
Interventions
Semaglutide, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 14, 2026, 2:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Preventing Diabetes in the Deep South: Extending Partnerships and Adapting Interventions to Reach Rural Communities at High Risk.

NCT04343872
View directory record Official record
Conditions
Pre-diabetes
Interventions
Receive lifestyle modification alone, Metformin therapy
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 5, 2024 · Synced Oct 14, 2026, 2:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Low-level Laser and Lifestyle Modifications

NCT05083442
View directory record Official record
Conditions
Overweight and Obesity, Weight Loss
Interventions
Low Level Laser Therapy, Sham (placebo)
Device · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 3, 2025 · Synced Oct 14, 2026, 2:46 PM EDT
Completed Phase 4 Interventional

A Phase IV, Multi-Center, Open-Label Trial of Sibutramine in Combination With a Hypocaloric Diet in Obese and Overweight Thai Subjects.

NCT00234988
View directory record Official record
Conditions
Obesity
Interventions
sibutramine hydochloride monohydrate
Drug
Lead sponsor
Abbott
Industry
Eligibility
18 Years to 65 Years
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2004
U.S. locations
1
States / cities
North Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 15, 2008 · Synced Oct 14, 2026, 2:46 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Effect of VI-0521 (Qsymia®) on Glomerular Filtration Rate (GFR) in Overweight or Obese Healthy Subjects

NCT02229214
View directory record Official record
Conditions
Obesity
Interventions
Qsymia, Placebo
Drug
Lead sponsor
VIVUS LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Lakewood, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 7, 2017 · Synced Oct 14, 2026, 2:46 PM EDT
Terminated Not applicable Interventional Results available

Safety and Efficacy of EndoBarrier in Subjects With Type 2 Diabetes Who Are Obese

NCT01728116
View directory record Official record
Conditions
Type 2 Diabetes, Obesity
Interventions
EndoBarrier, Sham Procedure
Device · Procedure
Lead sponsor
Morphic Medical Inc.
Industry
Eligibility
21 Years to 65 Years
Enrollment
325 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
25
States / cities
Birmingham, Alabama • Scottsdale, Arizona • Little Rock, Arkansas + 20 more
Source: ClinicalTrials.gov public record
Updated Feb 1, 2017 · Synced Oct 14, 2026, 2:46 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Prevalence and Cardiovascular Effects of Growth Hormone Deficiency in Abdominal Obesity

NCT00562796
View directory record Official record
Conditions
Obesity, Growth Hormone
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 55 Years
Enrollment
149 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 23, 2011 · Synced Oct 14, 2026, 2:46 PM EDT
Not listed Not applicable Interventional

Efficacy of IV Acetaminophen in Acute Post-Operative Pain Control in Laparoscopic Roux-en-Y Gastric Bypass Surgery (LRYGBP) Patients

NCT01460667
View directory record Official record
Conditions
Morbid Obesity
Interventions
IV acetaminophen, IV normal saline
Drug
Lead sponsor
McLaren Regional Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
1
States / cities
Flint, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 27, 2011 · Synced Oct 14, 2026, 2:46 PM EDT
Completed No phase listed Observational

Linking Activity, Nutrition, and Child Health

NCT04189926
View directory record Official record
Conditions
Obesity, Child Obesity
Interventions
Not listed
Lead sponsor
University of South Carolina
Other
Eligibility
6 Months to 36 Months
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 18, 2024 · Synced Oct 14, 2026, 2:46 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

DELPHI in Subjects at Risk for Stroke and Dementia

NCT03884647
View directory record Official record
Conditions
Stroke, Hypertension, Diabete Mellitus, Dyslipidemias, Sleep Disorder, Smoking, Overweight and Obesity, Familial Alzheimer Disease, Atrial Fibrillation, Cardiac Disease, Cognitive Impairment, Transient Ischemic Attack
Interventions
DELPhI system
Device
Lead sponsor
QuantalX Neuroscience
Industry
Eligibility
50 Years to 75 Years
Enrollment
335 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
3
States / cities
Walnut Creek, California • Atlanta, Georgia • Norwood, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 14, 2022 · Synced Oct 14, 2026, 2:46 PM EDT
Completed Not applicable Interventional Results available

Reducing Metabolic Dysregulation in Obese Latina Breast Cancer Survivors Using Physical Activity

NCT04717050
View directory record Official record
Conditions
Breast Cancer, Coronary Artery Disease, Stroke, Type2 Diabetes
Interventions
Progressive combine training (PCT), Attention Control (AC)
Behavioral
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 14, 2026, 2:46 PM EDT
Completed No phase listed Observational

Pharmacokinetics of Anti-epileptic Drugs in Obese Children

NCT02993861
View directory record Official record
Conditions
Epilepsy, Obese
Interventions
Anti-epileptics
Other
Lead sponsor
Christoph P Hornik, MD MPH
Other
Eligibility
2 Years to 18 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
10
States / cities
Aurora, Colorado • Wilmington, Delaware • Atlanta, Georgia + 7 more
Source: ClinicalTrials.gov public record
Updated Jun 4, 2020 · Synced Oct 14, 2026, 2:46 PM EDT
Completed Phase 3 Interventional Results available

Study of VI-0521 Compared to Placebo in Treatment of Diabetes and Obesity in Adults With Obesity-Related Co-Morbid Conditions

NCT00553787
View directory record Official record
Conditions
Obesity, Type 2 Diabetes
Interventions
VI-0521
Drug
Lead sponsor
VIVUS LLC
Industry
Eligibility
18 Years to 70 Years
Enrollment
2,487 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
6
States / cities
Birmingham, Alabama • Ridgefield, Connecticut • New York, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 10, 2012 · Synced Oct 14, 2026, 2:46 PM EDT
Completed No phase listed Observational

Johns Hopkins Weight Management Center Patient Data

NCT03321565
View directory record Official record
Conditions
Obesity
Interventions
Behavioral counseling and optional meal replacement program
Other
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years and older
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1990 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 10, 2021 · Synced Oct 14, 2026, 2:46 PM EDT
Not listed Early Phase 1 Interventional

Effect of Intense Multi-modal Training on Bone Health and Quality of Life in Persons With Spinal Cord Injury

NCT01386762
View directory record Official record
Conditions
Spinal Cord Injury, Obesity
Interventions
Exercise training
Other
Lead sponsor
California State University, San Marcos
Other
Eligibility
18 Years to 45 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
San Marcos, California
Source: ClinicalTrials.gov public record
Updated Jul 1, 2011 · Synced Oct 14, 2026, 2:46 PM EDT
Completed Not applicable Interventional Results available

Spatz Adjustable Balloon for Obesity (SABO)

NCT02812160
View directory record Official record
Conditions
Obesity
Interventions
Spatz3 Adjustable Balloon
Device
Lead sponsor
Spatz FGIA, Inc
Other
Eligibility
22 Years to 65 Years
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
7
States / cities
Chicago, Illinois • Metairie, Louisiana • Towson, Maryland + 4 more
Source: ClinicalTrials.gov public record
Updated May 28, 2021 · Synced Oct 14, 2026, 2:46 PM EDT
Completed Phase 3 Interventional

Evaluating the Safety and Efficacy of LIPO-202 for the Reduction of Central Abdominal Bulging Due to Subcutaneous Fat

NCT02397499
View directory record Official record
Conditions
Central Abdominal Bulging
Interventions
LIPO-202, Placebo
Drug
Lead sponsor
Neothetics, Inc
Industry
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2015
U.S. locations
31
States / cities
Tucson, Arizona • Hot Springs, Arkansas • Beverly Hills, California + 26 more
Source: ClinicalTrials.gov public record
Updated Jan 8, 2016 · Synced Oct 14, 2026, 2:46 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Garden-fresh Produce and Exercise Reduce Colon Cancer Risk

NCT03976284
View directory record Official record
Conditions
Garden-fresh Produce and Exercise (GFPE)
Interventions
Garden-fresh produce and exercise
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 6, 2019 · Synced Oct 14, 2026, 2:46 PM EDT
Not yet recruiting No phase listed Observational

Scale-Up Evaluation Trial of the Diabetes Prevention Program to Improve Obesity and Cardiometabolic Health After Traumatic Brain Injury

NCT07648901
View directory record Official record
Conditions
Traumatic Brain Injury, Brain Injuries, Traumatic, Brain Injury, Chronic
Interventions
Group Lifestyle Balance for People with TBI (GLB-TBI)
Behavioral
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 80 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Oct 14, 2026, 2:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Low-intensity Resistance Exercise and Diet on Arterial Function and Blood Pressure

NCT01371370
View directory record Official record
Conditions
Obesity, Pre-hypertension, Hypertension
Interventions
Resistance exercise training, Hypocaloric diet, Resistance exercise training & diet
Other
Lead sponsor
Florida State University
Other
Eligibility
40 Years to 65 Years · Female only
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Aug 5, 2014 · Synced Oct 14, 2026, 2:46 PM EDT